Nutrient reference values for bioactives: New approaches needed? A conference report

European Journal of Nutrition

Volumn 52, Issue 1 SUPPL., 2013, Pages 1-9

  Biesalski, Hans Konrad ^a   Erdman Jr , John W ^b   Hathcock, John ^c   Ellwood, Kathleen ^d   Beatty, Stephen ^e   Johnson, Elizabeth ^f   Marchioli, Roberto ^g   Lauritzen, Lotte ^h   Rice, Harry B ⁱ   Shao, Andrew ^j   Griffiths, James C ^c  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c International and Scientific Affairs   (United States)

^d Department of Social Sciences   (United States)

^e Ireland   (Ireland)

^f TUFTS UNIVERSITY   (United States)

^g Consorzio Mario Negri Sud ^*  (Italy)

^h UNIVERSITY OF COPENHAGEN   (Denmark)

ⁱ Global Organization for EPA and DHA Omega 3s (GOED)   (United States)

^j Herbalife   (United States)

more..

Author keywords

Adequate intake; Lutein; Mesozeaxanthin; N 3 long chain polyunsaturated fatty acids; Non essential nutrients; Nutrient reference values; Zeaxanthin

Indexed keywords

CAROTENOID; POLYUNSATURATED FATTY ACID; XANTHOPHYLL; ZEAXANTHIN; OMEGA 3 FATTY ACID;

ARTICLE; BRAIN; DIET; DIETARY FIBER; FOOD; HEALTH; HUMAN; NUTRIENT; REFERENCE VALUE; RETINA MACULA DEGENERATION; UNITED STATES; VISION; CHILD; CONFERENCE PAPER; FOOD PACKAGING; HEALTH CARE POLICY; HEALTH PROMOTION; NUTRITIONAL REQUIREMENT; PHYSIOLOGY;

BRAIN; CAROTENOIDS; CHILD; DIET; FATTY ACIDS, OMEGA-3; FOOD; FOOD LABELING; HEALTH PROMOTION; HUMANS; LUTEIN; MACULAR DEGENERATION; NUTRITION POLICY; NUTRITIONAL REQUIREMENTS; REFERENCE VALUES; UNITED STATES; VISION, OCULAR; XANTHOPHYLLS;

EID: 84874348502     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-013-0503-0     Document Type: Article

References (43)

1. Office of Disease Prevention and Health Promotion (2013) Dietary guidelines for Americans. Office of disease prevention and health promotion. http://health.gov/dietaryguidelines. Accessed 10 January 2013.
2. Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, Dhariwal KR, Park JB, Lazarev A, Graumlich JF, King J, Cantilena LR (1996) Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proc Natl Acad Sci USA 93:3704-3709. (Pubitemid 26125678)
3. EFSA Panel on Food Additives and Nutrient Sources Added to Food (2012) Scientific opinion on the re-evaluation of mixed carotenes (E 160a (i)) and beta-carotene (E 160a (ii)) as a food additive. EFSA J 10(3):2593. doi:10.2903/j.efsa.2012.259.3.
4. Johnson EJ, Neuringer M, Russell RM, Schalch W, Snodderly DM (2005) Nutritional manipulation of primate retinas. III Effects of lutein or zeaxanthin supplementation on adipose tissue and retina of xanthophyll-free monkeys. Invest Ophthalmol Vis Sci 46(2):692-702. (Pubitemid 40270354)
5. Bone RA, Landrum JT, Hime GW, Cains A, Zamor J (1993) Stereochemistry of the human macular carotenoids. Invest Ophthalmol Vis Sci 34(6):2033-2040. (Pubitemid 23148640)
6. Li B, Ahmed F, Bernstein PS (2010) Studies on the singlet oxygen scavenging mechanism of human macular pigment. Arch Biochem Biophys 504(1):56-60. doi:10.1016/j.abb.2010.07.024.
7. National Eye Institute (2011) Age-related eye disease study- results. National Eye Institute, National Institutes of Health. http://nei.nih.gov/amd. Accessed 10 January 2013.
8. Evans JR, Lawrenson JG (2012) Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane Database Syst Rev. doi:10.1002/14651858.CD000254.pub3.
9. Loughman J, Nolan JM, Howard AN, Connolly E, Meagher K, Beatty S (2012) The impact of macular pigment augmentation on visual performance using different carotenoid formulations. Invest Ophthalmol Vis Sci 53(12):7871-7878. doi:10.1167/iovs.12-10690.
10. Loughman J, Akkali MC, Beatty S, Scanlon G, Davison PA, O'Dwyer V, Cantwell T, Major P, Stack J, Nolan JM (2010) The relationship between macular pigment and visual performance. Vision Res 50(13):1249-1256. doi:10.1016/j.visres.2010.04.009.
11. Meagher KA, Thurnham DI, Beatty S, Howard AN, Connelly E, Cummins W, Nolan JM (2012) Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration. Br J Nutr 1-12. doi:10.1017/S0007114512 004837.
12. Connelly EE, Beatty S, Loughman J, Howard AN, Louw MS, Nolan JM (2011) Supplementation with all three macular carotenoids: response, stability, and safety. Invest Ophthalmol Vis Sci 52(12):9207-9217.
13. Johnson EJ (2012) A possible role for lutein and zeaxanthin in cognitive function in the elderly. Am J Clin Nutr 96(5):1161s- 1165s. doi:10.3945/ajcn. 112.034611.
14. Johnson EJ, Vishwanathan R, Schach W et al (2011) Brain levels of lutein (L) and zeaxanthin (Z) are related to cognitive function in centenarians. FASEB J 25(975):21.
15. Renzi LM, Iannaccone A, Johnson E, Kritchevsky S et al (2008) The relation between serum xanthophylls, fatty acids, macular pigment and cognitive function in the Health ABC Study. FASEB J 22(877):5.
16. Vishwanathan R, Neuringer M, Snodderly DM, Schalch W, Johnson EJ (2012) Macular lutein and zeaxanthin are related to brain lutein and zeaxanthin in primates. Nutr Neurosci. doi: 10.1179/14768230512Y.0000000024.
17. Johnson EJ, McDonald K, Caldarella SM, Chung HY, Troen AM, Snodderly DM (2008) Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Nutr Neurosci 11(2):75-83.
18. Lee YH, Bae SC, Song GG (2012) Omega-3 polyunsaturated fatty acids and the treatment of rheumatoid arthritis: A metaanalysis. Arch Med Res 43(5):356-362. doi:10.1016/j.arcmed. 2012.06.011.
19. Palmer DJ, Sullivan T, Gold MS, Prescott SL, Heddle R, Gibson RA, Makrides M (2012) Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial. BMJ 344:e184. doi: 10.1136/bmj.e184.
20. Nwaru BI, Erkkola M, Lumia M, Kronberg-Kippila C, Ahonen S, Kaila M, Ilonen J, Simell O, Knip M, Veijola R, Virtanen SM (2012) Maternal intake of fatty acids during pregnancy and allergies in the offspring. Br J Nutr 108(4):720-732. doi:10.1017/S0007114511005940.
21. Mozaffarian D, Wu JH (2011) Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol 58(20):2047-2067. doi: 10.1016/j.jacc.2011.06.063.
22. Mozaffarian D (2009) Fish, mercury, selenium and cardiovascular risk: current evidence and unanswered questions. Int J Environ Res Public Health 6(6):1894-1916. doi:10.3390/ijerph6061894.
23. Trial Investigators ORIGIN, Bosch J, Gerstein HC, Dagenais GR, Diaz R, Dyal L, Jung H, Maggiono AP, Probstfield J, Ramachandran A, Riddle MC, Ryden LE, Yusuf S (2012) n-3 Fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med 367(4):309-318. doi:10.1056/NEJMoa1203859.
24. Eussen SR, Geleijnse JM, Giltay EJ, Rompelberg CJ, Klungel OH, Kromhout D (2012) Effects of n-3 fatty acids on major cardiovascular events in statin users and non-users with a history of myocardial infarction. Eur Heart J 33(13):1582-1588. doi: 10.1093/eurheartj/ehr499.
25. Zheng J, Huang T, Yu Y, Hu X, Yang B, Li D (2012) Fish consumption and CHD mortality: An updated meta-analysis of seventeen cohort studies. Public Health Nutr 15(4):725-737. doi: 10.1017/S1368980011002254.
26. Harris WS, Klurfeld DM (2011) Twentieth-century trends in essential fatty acid intakes and the predicted omega-3 index: evidence versus estimates. Am J Clin Nutr 93(5):907-908. doi: 10.3945/ajcn.111.014365.
27. Harris WS (2007) Omega-3 fatty acids and cardiovascular disease: A case for omega-3 index as a new risk factor. Pharmacol Res 55(3):217-223. (Pubitemid 46518155)
28. Block RC, Harris WS, Pottala JV (2008) Determinants of blood cell omega-3 fatty acid content. Open Biomark J 1:1-6.
29. Mozaffarian D, Geelen A, Brouwer IA, Geleijnse JM, Zock PL, Katan MB (2005) Effects of fish oil on heart rate in humans: A meta-analysis of randomized controlled trials. Circulation 112(13):1945-1952. (Pubitemid 41377412)
30. Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM (2010) n-6 Fatty acid-specific and mixed polyunsaturated dietary interventions have different effects on CHD risk: A meta-analysis of randomised controlled trials. Br J Nutr 104(11):1586-1600. doi: 10.1017/S0007114510004010.
31. Virtanen JK, Mozaffarian D, Chiuve SE, Rimm EB (2008) Fish consumption and risk of major chronic disease in men. Am J Clin Nutr 88(6):1618-1625. doi:10.3945/ajcn.2007.25816.
32. Vedtofte MS, Jakobsen MU, Lauritzen L, Heitmann BL (2011) Dietary a-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease. Am J Clin Nutr 94(4): 1097-1103. doi:10.3945/ajcn.111.018762.
33. Codex Alimentarius (1985) Codex guidelines on nutrition labelling (CAC/GL 2-1985, Rev. 1997). FAO corporate document repository. http://www.fao.org/ docrep/005/Y2770E/y2770e06.htm. Accessed 10 January 2013.
34. US Food and Drug Administration (1997) Substances affirmed as generally recognized as safe: menhaden oil. Fed Reg 62(10): 30751-30757.
35. Mitre Corporation (1989) Health effects of refined menhaden oil. National Technical Information Service, order no. PB89-182398.
36. IOM (2005) Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids (Macronutrients). National Academies Press, Washington, DC.
37. German Federal Institute for Risk Assessment (BfR) (2009) Fur die Anreicherung von Lebensmitteln mit Omega-3-Fettsauren empfiehlt das BfR die Festsetzung von Hochstmengen. Bundesinstitut fur Risikobewertung. http://www.bfr.bund.de/cm/343/fuer-die-anreicherung-von-lebensmitteln-mit-omega- 3-fettsaeuren-empfiehlt-das-bfr-die-festsetzung-von-hoechstmengen.pdf. Accessed 14 January 2013.
38. Norwegian Scientific Committee for Food Safety (VKM) (2011) Evaluation of negative and positive health effects of n-3 fatty acids as constituents of food supplements and fortified foods. Norwegian Scientific Committee for Food Safety. http://www.vkm.no/dav/c7a41adb79.pdf. Accessed 14 January 2013.
39. EFSA Panel on Dietetic Products, Nutrition and Allergies (2012) Scientific Opinion related to the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA). EFSA J 10(7):2815. doi:10.2903/j.efsa.2012.2815.
40. Spherix Consulting, Inc. for and on behalf of the Global Organization for EPA and DHA Omega-3s (GOED) (2012) Hazard characterization of the long-chain polyunsaturated n-3 fatty acids, DHA, EPA and DPA. Executive Summary available upon request from GOED.
41. Shao A, Hathcock JN (2006) Risk assessment for the carotenoids lutein and lycopene. Regul Toxicol Pharmacol 45(3):289-298. (Pubitemid 44066631)
42. Shao A, Hathcock JN (2008) Risk assessment for the amino acids taurine, L-glutamine and L-arginine. Regul Toxicol Pharmacol 50(3):376-399.
43. Hathcock JN, Shao A (2006) Risk assessment for coenzyme Q10 (Ubiquinone). Regul Toxicol Pharmacol 45(3):282-288. (Pubitemid 44066629)