Early changes in Homer1 proteins in the spinal dorsal horn are associated with loose ligation of the rat sciatic nerve

Anesthesia and Analgesia

Volumn 109, Issue 6, 2009, Pages 2000-2007

  Miletic, Gordana ^a   Driver, Ashley M ^b   Miyabe Nishiwaki, Takako ^c   Miletic, Vjekoslav ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; DIZOCILPINE; PROTEIN HOMER 1A; PROTEIN HOMER 1B; PROTEIN HOMER 1C; SMALL INTERFERING RNA; U 01026; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LEVEL; CENTRIFUGATION; CONTROLLED STUDY; HYPERALGESIA; IMMUNOBLOTTING; MALE; NERVE CELL PLASTICITY; NERVE INJURY; NERVE LIGATION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; RNA INTERFERENCE; SCIATIC NERVE; SHAM PROCEDURE; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; THERMAL STIMULATION; WEIGHT BEARING; WESTERN BLOTTING;

EID: 73949093272     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3181beea9b     Document Type: Article

References (22)

1. Boeckers TM. The postsynaptic density. Cell Tissue Res 2006;326:409-422
2. Sheng M, Hoogenraad CC. The postsynaptic architecture of excitatory synapses: a more quantitative view. Annu Rev Biochem 2007;76:823-847
3. de Bartolomeis A, Iasevoli F. The homer family and the signal transduction system at glutamatergic postsynaptic density: potential role in behavior and pharmacotherapy. Psychopharmacol Bull 2003;37:51-83
4. 2+ signaling by excitable and non-excitable cells. Cell Calcium 2007;42:363-371
5. Sandkuhler J. Models and mechanisms of hyperalgesia and allodynia. Prog Brain Res 2009;89:707-758
6. Miletic G, Miyabe T, Gebhardt GJ, Miletic V. Increased levels of Homer1b/c and Shank1a in the post-synaptic density of spinal dorsal horn neurons are associated with neuropathic pain in rats. Neurosci Lett 2005;386:189-193
7. Miyabe T, Miletic G, Miletic V. Loose ligation of the sciatic nerve in rats elicits transient up-regulation of Homer1a gene expression in the spinal dorsal horn. Neurosci Lett 2006;398:296-299
8. Tappe A, Klugmann M, Luo C, Hirlinger D, Agarwal N, Benrath J, Ehrengruber MU, During MJ, Kuner R. Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain. Nat Med 2006;12:677-681
9. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983;16:109-110
10. Hargreaves K, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988;32:77-88
11. Mestre C, Pelissier T, Fialip J, Wilcox G, Eschalier AJ. A method to perform direct transcutaneous intrathecal injection in rats. J Pharmacol Toxicol Methods 1994;32:197-200
12. Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988;33:87-107
13. Miletic G, Miletic V. Loose ligation of the sciatic nerve is associated with TrkB receptor-dependent decreases in KCC2 protein levels in the ipsilateral spinal dorsal horn. Pain 2008;137:532-539
14. Keuren-Jensen KV, Cline HT. Visual experience regulates metabotropic glutamate receptor-mediated plasticity of AMPA receptor synaptic transmission by homer1a induction. J Neurosci 2006;26:7575-7580
15. Zhang GC, Mao LM, Liu XY, Parelkar NK, Arora A, Yang L, Hains M, Fibuch EE, Wang JQ. In vivo regulation of homer1a expression in the striatum by cocaine. Mol Pharmacol 2007;71:1148-1158
16. Inoue Y, Udo H, Inokuchi K, Sugiyama H. Homer1a regulates the activity-induced remodeling of synaptic structures in cultured hippocampal neurons. Neuroscience 2007;150:841-852
17. Szumlinski KK, Ary AW, Lominac KD. Homers regulate druginduced neuroplasticity: implications for addiction. Biochem Pharmacol 2008;75:112-133
18. Inoue Y, Honkura N, Kato A, Ogawa S, Udo H, Inokuchi K, Sugiyama H. Activity-inducible protein Homer1a/Vesl-1S promotes redistribution of postsynaptic protein Homer1c/Vesl-1L in cultured rat hippocampal neurons. Neurosci Lett 2004;354:143-147
19. Malenka RC, Bear MF. LTP and LTD: an embarrassment of riches. Neuron 2004;44:5-21
20. Millan MJ. The induction of pain: an integrative review. Prog Neurobiol 1999;57:1-164
21. Ehrengruber MU, Kato A, Inokuchi K, Hennou S. Homer/Vesl proteins and their roles in CNS neurons. Mol Neurobiol 2004;29:213-227
22. Worley PF, Zeng W, Huang G, Kim JY, Shin DM, Kim MS, Yuan JP, Kiselyov K, Muallem S. Homer proteins in Ca2+ signaling by excitable and non-excitable cells. Cell Calcium 2007;42:363-371