Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 162, Issue 2, 2013, Pages 87-95

  Myles Worsley, Marina ^a   Tiobech, Josepha ^b   Browning, Sharon R ^c   Korn, Jeremy ^a   Goodman, Sarah ^a   Gentile, Karen ^a   Melhem, Nadine ^d   Byerley, William ^e   Faraone, Stephen V ^a   Middleton, Frank A ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b Republic of Palau Ministry of Health   (Palau)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bipolar schizoaffective disorder; Copy number variant; Extended multiplex pedigree; Glutamate; Population isolate; Psychotic disorders; Schizophrenia

Indexed keywords

AMINO ACID; EXCITATORY AMINO ACID TRANSPORTER 3;

AMPLICON; ARTICLE; COPY NUMBER VARIATION; GENE DELETION; GENE MAPPING; GENE MUTATION; GENETIC RISK; GENETIC SCREENING; HUMAN; LINKAGE ANALYSIS; MEDICAL GENETICS; MICROARRAY ANALYSIS; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SIBLING; TRANSCRIPTION INITIATION SITE;

BIPOLAR DISORDER; CHROMOSOME SEGREGATION; CHROMOSOMES, HUMAN, PAIR 9; DNA COPY NUMBER VARIATIONS; EXCITATORY AMINO ACID TRANSPORTER 3; FAMILY CHARACTERISTICS; FEMALE; GENE DELETION; GENETIC ASSOCIATION STUDIES; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PEDIGREE; PHYSICAL CHROMOSOME MAPPING; REPRODUCIBILITY OF RESULTS; SCHIZOPHRENIA;

EID: 84874161631     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32125     Document Type: Article

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