-
1
-
-
0034702026
-
Disruption of two novel genes by a translocation co-segregating with schizophrenia
-
Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, et al. (2000) Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 9: 1415-1423.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1415-1423
-
-
Millar, J.K.1
Wilson-Annan, J.C.2
Anderson, S.3
Christie, S.4
Taylor, M.S.5
-
2
-
-
0034927864
-
Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family
-
Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ, et al. (2001) Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet 69: 428-433.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 428-433
-
-
Blackwood, D.H.1
Fordyce, A.2
Walker, M.T.3
St Clair, D.M.4
Porteous, D.J.5
-
3
-
-
81555203199
-
Linking neurodevelopmental and synaptic theories of mental illness through DISC1
-
Brandon NJ, Sawa A, (2011) Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat Rev Neurosci 12: 707-722.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 707-722
-
-
Brandon, N.J.1
Sawa, A.2
-
4
-
-
81455155113
-
DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness
-
Soares DC, Carlyle BC, Bradshaw NJ, Porteous DJ, (2011) DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness. ACS Chem Neurosci 2: 609-632.
-
(2011)
ACS Chem Neurosci
, vol.2
, pp. 609-632
-
-
Soares, D.C.1
Carlyle, B.C.2
Bradshaw, N.J.3
Porteous, D.J.4
-
5
-
-
28544453286
-
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
-
Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, et al. (2005) A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol 7: 1167-1178.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 1167-1178
-
-
Kamiya, A.1
Kubo, K.2
Tomoda, T.3
Takaki, M.4
Youn, R.5
-
6
-
-
34548806900
-
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain
-
Duan X, Chang JH, Ge S, Faulkner RL, Kim JY, et al. (2007) Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell 130: 1146-1158.
-
(2007)
Cell
, vol.130
, pp. 1146-1158
-
-
Duan, X.1
Chang, J.H.2
Ge, S.3
Faulkner, R.L.4
Kim, J.Y.5
-
7
-
-
62149083806
-
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling
-
Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, et al. (2009) Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 136: 1017-1031.
-
(2009)
Cell
, vol.136
, pp. 1017-1031
-
-
Mao, Y.1
Ge, X.2
Frank, C.L.3
Madison, J.M.4
Koehler, A.N.5
-
8
-
-
77649192502
-
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
-
Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, et al. (2010) Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat Neurosci 13: 327-332.
-
(2010)
Nat Neurosci
, vol.13
, pp. 327-332
-
-
Hayashi-Takagi, A.1
Takaki, M.2
Graziane, N.3
Seshadri, S.4
Murdoch, H.5
-
9
-
-
76849102959
-
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits
-
Niwa M, Kamiya A, Murai R, Kubo K, Gruber AJ, et al. (2010) Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron 65: 480-489.
-
(2010)
Neuron
, vol.65
, pp. 480-489
-
-
Niwa, M.1
Kamiya, A.2
Murai, R.3
Kubo, K.4
Gruber, A.J.5
-
10
-
-
35448988145
-
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans
-
Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, et al. (2007) Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci U S A 104: 14501-14506.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14501-14506
-
-
Hikida, T.1
Jaaro-Peled, H.2
Seshadri, S.3
Oishi, K.4
Hookway, C.5
-
11
-
-
79951813355
-
Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders
-
Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, et al. (2011) Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. Mol Psychiatry.
-
(2011)
Mol Psychiatry
-
-
Ayhan, Y.1
Abazyan, B.2
Nomura, J.3
Kim, R.4
Ladenheim, B.5
-
12
-
-
33744985583
-
DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex
-
Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, et al. (2006) DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J Comp Neurol 497: 436-450.
-
(2006)
J Comp Neurol
, vol.497
, pp. 436-450
-
-
Kirkpatrick, B.1
Xu, L.2
Cascella, N.3
Ozeki, Y.4
Sawa, A.5
-
13
-
-
80053132702
-
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function
-
Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, et al. (2011) The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Mol Psychiatry 16: 1006-1023.
-
(2011)
Mol Psychiatry
, vol.16
, pp. 1006-1023
-
-
Wang, Q.1
Charych, E.I.2
Pulito, V.L.3
Lee, J.B.4
Graziane, N.M.5
-
14
-
-
52949109794
-
Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain
-
Faulkner RL, Jang MH, Liu XB, Duan X, Sailor KA, et al. (2008) Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain. Proc Natl Acad Sci U S A 105: 14157-14162.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14157-14162
-
-
Faulkner, R.L.1
Jang, M.H.2
Liu, X.B.3
Duan, X.4
Sailor, K.A.5
-
15
-
-
83755183704
-
Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice
-
Kvajo M, McKellar H, Drew LJ, Lepagnol-Bestel AM, Xiao L, et al. (2011) Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice. Proc Natl Acad Sci U S A 108: E1349-1358.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
-
-
Kvajo, M.1
McKellar, H.2
Drew, L.J.3
Lepagnol-Bestel, A.M.4
Xiao, L.5
-
16
-
-
79960916466
-
DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway
-
Flores R 3rd, Hirota Y, Armstrong B, Sawa A, Tomoda T, (2011) DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway. Neurosci Res 71: 71-77.
-
(2011)
Neurosci Res
, vol.71
, pp. 71-77
-
-
Flores 3rd., R.1
Hirota, Y.2
Armstrong, B.3
Sawa, A.4
Tomoda, T.5
-
17
-
-
79151471696
-
Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons
-
121
-
Atkin TA, MacAskill AF, Brandon NJ, Kittler JT, (2011) Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons. Mol Psychiatry 16: 122-124, 121.
-
(2011)
Mol Psychiatry
, vol.16
, pp. 122-124
-
-
Atkin, T.A.1
MacAskill, A.F.2
Brandon, N.J.3
Kittler, J.T.4
-
18
-
-
79955479720
-
Regulation of axonal mitochondrial transport and its impact on synaptic transmission
-
Cai Q, Davis ML, Sheng ZH, (2011) Regulation of axonal mitochondrial transport and its impact on synaptic transmission. Neurosci Res 70: 9-15.
-
(2011)
Neurosci Res
, vol.70
, pp. 9-15
-
-
Cai, Q.1
Davis, M.L.2
Sheng, Z.H.3
-
19
-
-
58149343267
-
Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of neuronal migration disorder
-
Manent JB, Wang Y, Chang Y, Paramasivam M, LoTurco JJ, (2009) Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of neuronal migration disorder. Nat Med 15: 84-90.
-
(2009)
Nat Med
, vol.15
, pp. 84-90
-
-
Manent, J.B.1
Wang, Y.2
Chang, Y.3
Paramasivam, M.4
LoTurco, J.J.5
-
20
-
-
77957265898
-
Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi
-
Kubo K, Tomita K, Uto A, Kuroda K, Seshadri S, et al. (2010) Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi. Biochem Biophys Res Commun 400: 631-637.
-
(2010)
Biochem Biophys Res Commun
, vol.400
, pp. 631-637
-
-
Kubo, K.1
Tomita, K.2
Uto, A.3
Kuroda, K.4
Seshadri, S.5
-
21
-
-
34250800258
-
Evidence for activity-dependent cortical wiring: formation of interhemispheric connections in neonatal mouse visual cortex requires projection neuron activity
-
Mizuno H, Hirano T, Tagawa Y, (2007) Evidence for activity-dependent cortical wiring: formation of interhemispheric connections in neonatal mouse visual cortex requires projection neuron activity. J Neurosci 27: 6760-6770.
-
(2007)
J Neurosci
, vol.27
, pp. 6760-6770
-
-
Mizuno, H.1
Hirano, T.2
Tagawa, Y.3
-
22
-
-
77955395763
-
Visualizing the distribution of synapses from individual neurons in the mouse brain
-
Li L, Tasic B, Micheva KD, Ivanov VM, Spletter ML, et al. (2010) Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS One 5: e11503.
-
(2010)
PLoS One
, vol.5
-
-
Li, L.1
Tasic, B.2
Micheva, K.D.3
Ivanov, V.M.4
Spletter, M.L.5
-
24
-
-
77955057373
-
Cell biology of Ca2+-triggered exocytosis
-
Pang ZP, Sudhof TC, (2010) Cell biology of Ca2+-triggered exocytosis. Curr Opin Cell Biol 22: 496-505.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 496-505
-
-
Pang, Z.P.1
Sudhof, T.C.2
-
25
-
-
70349465009
-
DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
-
Nakata K, Lipska BK, Hyde TM, Ye T, Newburn EN, et al. (2009) DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc Natl Acad Sci U S A 106: 15873-15878.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 15873-15878
-
-
Nakata, K.1
Lipska, B.K.2
Hyde, T.M.3
Ye, T.4
Newburn, E.N.5
-
26
-
-
27844499290
-
Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release
-
Maximov A, Sudhof TC, (2005) Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release. Neuron 48: 547-554.
-
(2005)
Neuron
, vol.48
, pp. 547-554
-
-
Maximov, A.1
Sudhof, T.C.2
-
27
-
-
33646800207
-
Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release
-
Pang ZP, Sun J, Rizo J, Maximov A, Sudhof TC, (2006) Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release. EMBO J 25: 2039-2050.
-
(2006)
EMBO J
, vol.25
, pp. 2039-2050
-
-
Pang, Z.P.1
Sun, J.2
Rizo, J.3
Maximov, A.4
Sudhof, T.C.5
-
28
-
-
36749078085
-
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
-
Sun J, Pang ZP, Qin D, Fahim AT, Adachi R, et al. (2007) A dual-Ca2+-sensor model for neurotransmitter release in a central synapse. Nature 450: 676-682.
-
(2007)
Nature
, vol.450
, pp. 676-682
-
-
Sun, J.1
Pang, Z.P.2
Qin, D.3
Fahim, A.T.4
Adachi, R.5
-
29
-
-
37749053855
-
Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation
-
Kang JS, Tian JH, Pan PY, Zald P, Li C, et al. (2008) Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell 132: 137-148.
-
(2008)
Cell
, vol.132
, pp. 137-148
-
-
Kang, J.S.1
Tian, J.H.2
Pan, P.Y.3
Zald, P.4
Li, C.5
-
30
-
-
70350444463
-
KIF5B motor adaptor syntabulin maintains synaptic transmission in sympathetic neurons
-
Ma H, Cai Q, Lu W, Sheng ZH, Mochida S, (2009) KIF5B motor adaptor syntabulin maintains synaptic transmission in sympathetic neurons. J Neurosci 29: 13019-13029.
-
(2009)
J Neurosci
, vol.29
, pp. 13019-13029
-
-
Ma, H.1
Cai, Q.2
Lu, W.3
Sheng, Z.H.4
Mochida, S.5
|