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Volumn 3, Issue MAR, 2012, Pages

Subversion and utilization of host innate defense by Leishmania amazonensis

Author keywords

Immunopathogenesis; Innate immunity; Leishmania amazonensis; Parasite adaptation

Indexed keywords


EID: 84874140962     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2012.00058     Document Type: Review
Times cited : (46)

References (53)
  • 2
    • 33744965065 scopus 로고    scopus 로고
    • Endosome sorting and autophagy are essential for dif-ferentiation and virulence of Leish-mania major
    • Besteiro, S., Williams, R. A., Morrison, L. S., Coombs, G. H., and Mot-Tram,J. C. (2006). Endosome sorting and autophagy are essential for dif-ferentiation and virulence of Leish-mania major. J. Biol. Chem. 281, 11384-11396.
    • (2006) J. Biol. Chem. , vol.281 , pp. 11384-11396
    • Besteiro, S.1    Williams, R.A.2    Morrison, L.S.3    Coombs, G.H.4    Mot-Tram, J.C.5
  • 3
    • 77952470243 scopus 로고    scopus 로고
    • Leishmania interferes with host cell signaling to devise a survival strategy
    • 109189
    • Bhardwaj, S., Srivastava, N., Sudan, R., and Saha, B. (2010). Leishmania interferes with host cell signaling to devise a survival strategy. J. Biomed. Biotechnol. 109189, 1-3.
    • (2010) J. Biomed. Biotechnol. , pp. 1-3
    • Bhardwaj, S.1    Srivastava, N.2    Sudan, R.3    Saha, B.4
  • 4
    • 65649113275 scopus 로고    scopus 로고
    • Altered dendritic cell phe-notype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase ERK
    • Boggiatto, P. M., Jie, F., Ghosh, M., Gibson-Corley,K. N.,Ramer-Tait,A. E., Jones, D. E., and Petersen, C. A. (2009). Altered dendritic cell phe-notype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase, ERK. Am. J. Pathol. 174, 1818-1826.
    • (2009) Am. J. Pathol. , vol.174 , pp. 1818-1826
    • Boggiatto, P.M.1    Jie, F.2    Ghosh, M.3    Gibson-Corley, K.N.4    Ramer-Tait, A.E.5    Jones, D.E.6    Petersen, C.A.7
  • 5
    • 34248217509 scopus 로고    scopus 로고
    • Leishmania amazonensis: multiple receptor-ligand interac-tions are involved in amastigote infection of human dendritic cells
    • Bosetto, M. C., and Giorgio, S. (2007). Leishmania amazonensis: multiple receptor-ligand interac-tions are involved in amastigote infection of human dendritic cells. Exp. Parasitol. 116, 306-310.
    • (2007) Exp. Parasitol. , vol.116 , pp. 306-310
    • Bosetto, M.C.1    Giorgio, S.2
  • 8
    • 79951910694 scopus 로고    scopus 로고
    • Autophagy in immu-nity and cell-autonomous defense against intracellular microbes
    • Deretic,V. (2011). Autophagy in immu-nity and cell-autonomous defense against intracellular microbes. Immunol. Rev. 240, 92-104.
    • (2011) Immunol. Rev. , vol.240 , pp. 92-104
    • Deretic, V.1
  • 9
    • 67649607465 scopus 로고    scopus 로고
    • Autophagy, immunity, and micro-bial adaptations
    • Deretic, V., and Levine, B. (2009). Autophagy, immunity, and micro-bial adaptations. Cell Host Microbe 5, 527-549.
    • (2009) Cell Host Microbe , vol.5 , pp. 527-549
    • Deretic, V.1    Levine, B.2
  • 10
    • 82255195421 scopus 로고    scopus 로고
    • Phos-phatidylserine exposure by Tox-oplasma gondii is fundamental to balance the immune response granting survival of the parasite and of the host
    • doi:10.1371/journal.pone. 0027867
    • Dos Santos, T. A., Portes Jde, A., Damasceno-Sa, J. C., Caldas, L. A., de Souza, W., Damatta, R. A., and Seabra, S. H. (2011). Phos-phatidylserine exposure by Tox-oplasma gondii is fundamental to balance the immune response granting survival of the parasite and of the host. PLoS ONE 6, e27867. doi:10.1371/journal.pone. 0027867
    • (2011) PLoS ONE , vol.6
    • Dos Santos, T.A.1    Portes Jde, A.2    Damasceno-Sa, J.C.3    Caldas, L.A.4    de Souza, W.5    Damatta, R.A.6    Seabra, S.H.7
  • 11
    • 69449085100 scopus 로고    scopus 로고
    • GM-CSF-and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling
    • Fleetwood, A. J., Dinh, H., Cook, A. D., Hertzog, P. J., and Hamilton, J. A. (2009). GM-CSF-and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling. J. Leukoc. Biol. 86, 411-421.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 411-421
    • Fleetwood, A.J.1    Dinh, H.2    Cook, A.D.3    Hertzog, P.J.4    Hamilton, J.A.5
  • 12
    • 78549259414 scopus 로고    scopus 로고
    • Histopatho-logical analysis of initial cellular response in TLR-2 deficient mice experimentally infected by Leishma-nia (L ) amazonensis
    • Guerra, C. S., Silva, R. M., Carvalho, L. O., Calabrese, K. S., Bozza, P. T., and Corte-Real, S. (2010). Histopatho-logical analysis of initial cellular response in TLR-2 deficient mice experimentally infected by Leishma-nia (L.) amazonensis. Int. J. Exp. Pathol. 91, 451-459.
    • (2010) Int. J. Exp. Pathol. , vol.91 , pp. 451-459
    • Guerra, C.S.1    Silva, R.M.2    Carvalho, L.O.3    Calabrese, K.S.4    Bozza, P.T.5    Corte-Real, S.6
  • 14
    • 0043267774 scopus 로고    scopus 로고
    • Impaired expression of inflamma-tory cytokines and chemokines at early stages of infection with Leish-mania amazonensis
    • Ji, J., Sun, J., and Soong, L. (2003). Impaired expression of inflamma-tory cytokines and chemokines at early stages of infection with Leish-mania amazonensis. Infect. Immun. 71, 4278-4288.
    • (2003) Infect. Immun. , vol.71 , pp. 4278-4288
    • Ji, J.1    Sun, J.2    Soong, L.3
  • 15
    • 62749130608 scopus 로고    scopus 로고
    • Leishmania commandeers the host inflammatory response through neutrophils
    • Jochim, R. C., and Teixeira, C. (2009). Leishmania commandeers the host inflammatory response through neutrophils. Trends Para-sitol. 25, 145-147.
    • (2009) Trends Para-sitol , vol.25 , pp. 145-147
    • Jochim, R.C.1    Teixeira, C.2
  • 17
    • 61549139110 scopus 로고    scopus 로고
    • IFN-beta impairs superoxide-dependent par-asite killing in human macrophages: evidence for a deleterious role of SOD1 in cutaneous leishmaniasis
    • Khouri, R., Bafica, A., Silva Mda, P., Noronha, A., Kolb, J. P., Wietzerbin, J., Barral, A., Barral-Netto, M., and Van Weyenbergh,J. (2009). IFN-beta impairs superoxide-dependent par-asite killing in human macrophages: evidence for a deleterious role of SOD1 in cutaneous leishmaniasis. J. Immunol. 182, 2525-2531.
    • (2009) J. Immunol. , vol.182 , pp. 2525-2531
    • Khouri, R.1    Bafica, A.2    Silva Mda, P.3    Noronha, A.4    Kolb, J.P.5    Wietzerbin, J.6    Barral, A.7    Barral-Netto, M.8    Van Weyenbergh, J.9
  • 18
    • 37549051275 scopus 로고    scopus 로고
    • TLR9 signaling is essen-tial for the innate NK cell response in murine cutaneous leishmaniasis
    • Liese, J., Schleicher, U., and Bogdan, C. (2007). TLR9 signaling is essen-tial for the innate NK cell response in murine cutaneous leishmaniasis. Eur. J. Immunol. 37, 3424-3434.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 3424-3434
    • Liese, J.1    Schleicher, U.2    Bogdan, C.3
  • 19
    • 41649111868 scopus 로고    scopus 로고
    • The innate immune response against Leishmania para-sites
    • Liese, J., Schleicher, U., and Bogdan, C. (2008). The innate immune response against Leishmania para-sites. Immunobiology 213, 377-387.
    • (2008) Immunobiology , vol.213 , pp. 377-387
    • Liese, J.1    Schleicher, U.2    Bogdan, C.3
  • 20
    • 80053242785 scopus 로고    scopus 로고
    • Metabolic pathways required for the intracellular survival of Leish-mania
    • McConville, M. J., and Naderer, T. (2011). Metabolic pathways required for the intracellular survival of Leish-mania. Annu.Rev.Microbiol.65, 543-561.
    • (2011) Annu. Rev. Microbiol. , vol.65 , pp. 543-561
    • McConville, M.J.1    Naderer, T.2
  • 21
    • 4844223738 scopus 로고    scopus 로고
    • Does the Leishmania major paradigm of pathogenesis and pro-tection hold for New World cuta-neous leishmaniases or the vis-ceral disease?
    • McMahon-Pratt, D., and Alexander, J. (2004). Does the Leishmania major paradigm of pathogenesis and pro-tection hold for New World cuta-neous leishmaniases or the vis-ceral disease? Immunol. Rev. 201, 206-224.
    • (2004) Immunol Rev , vol.201 , pp. 206-224
    • McMahon-Pratt, D.1    Alexander, J.2
  • 22
    • 34249669128 scopus 로고    scopus 로고
    • Macrophage killing of Leishmania amazonensis amastig-otes requires both nitric oxide and superoxide
    • Mukbel, R. M., Patten, C. Jr., Gibson, K., Ghosh, M., Petersen, C., and Jones, D. E. (2007). Macrophage killing of Leishmania amazonensis amastig-otes requires both nitric oxide and superoxide. Am. J. Trop. Med. Hyg. 76, 669-675.
    • (2007) Am. J. Trop. Med. Hyg. , vol.76 , pp. 669-675
    • Mukbel, R.M.1    Patten Jr., C.2    Gibson, K.3    Ghosh, M.4    Petersen, C.5    Jones, D.E.6
  • 23
    • 80455130023 scopus 로고    scopus 로고
    • The Coxiella burnetii Dot/Icm system creates a comfortable home through lysosomal renovation
    • e00226-11
    • Newton, H. J., and Roy, C. R. (2011). The Coxiella burnetii Dot/Icm system creates a comfortable home through lysosomal renovation. MBio. e00226-11, 1-3.
    • (2011) MBio , pp. 1-3
    • Newton, H.J.1    Roy, C.R.2
  • 25
    • 64549137195 scopus 로고    scopus 로고
    • Transcriptional signatures of BALB/c mouse macrophages hous-ing multiplying Leishmania amazo-nensis amastigotes
    • doi:10.1186/1471-2164-10-119
    • Osorio y Fortea, J., de La Llave, E., Regnault, B., Coppee, J. Y., Milon, G., Lang, T., and Prina, E. (2009). Transcriptional signatures of BALB/c mouse macrophages hous-ing multiplying Leishmania amazo-nensis amastigotes. BMC Genomics 10, 119. doi:10.1186/1471-2164-10-119
    • (2009) BMC Genomics , vol.10 , pp. 119
    • Osorio, F.J.1    de La Llave, E.2    Regnault, B.3    Coppee, J.Y.4    Milon, G.5    Lang, T.6    Prina, E.7
  • 26
    • 34548570210 scopus 로고    scopus 로고
    • Unveiling pathways used by Leishmania amazonensis amastigotes to subvert macrophage function
    • Osorio y Fortea, J., Prina, E., de La Llave, E., Lecoeur, H., Lang, T., and Milon, G. (2007). Unveiling pathways used by Leishmania amazonensis amastigotes to subvert macrophage function. Immunol. Rev. 219, 66-74.
    • (2007) Immunol. Rev. , vol.219 , pp. 66-74
    • Osorio, F.J.1    Prina, E.2    de La Llave, E.3    Lecoeur, H.4    Lang, T.5    Milon, G.6
  • 29
    • 4644249049 scopus 로고    scopus 로고
    • The T-cell anergy induced by Leishmania ama-zonensis antigens is related with defective antigen presentation and apoptosis
    • Pinheiro, R. O., Pinto, E. F., Bened-Ito, A. B., Lopes, U. G., and Rossi-Bergmann, B. (2004). The T-cell anergy induced by Leishmania ama-zonensis antigens is related with defective antigen presentation and apoptosis. An. Acad. Bras. Cienc. 76, 519-527.
    • (2004) An. Acad. Bras. Cienc. , vol.76 , pp. 519-527
    • Pinheiro, R.O.1    Pinto, E.F.2    Bened-Ito, A.B.3    Lopes, U.G.4    Rossi-Bergmann, B.5
  • 30
    • 27644492094 scopus 로고    scopus 로고
    • TGF-β-associated enhanced suscep-tibility to leishmaniasis following intramuscular vaccination of mice with Leishmania amazonensis anti-gens
    • Pinheiro, R. O., Pinto, E. F., Lopes, J. R., Guedes, H. L., Fentanes, R. F., and Rossi-Bergmann, B. (2005). TGF-β-associated enhanced suscep-tibility to leishmaniasis following intramuscular vaccination of mice with Leishmania amazonensis anti-gens. Microbes Infect. 7, 1317- 1323.
    • (2005) Microbes Infect , vol.7 , pp. 1317-1323
    • Pinheiro, R.O.1    Pinto, E.F.2    Lopes, J.R.3    Guedes, H.L.4    Fentanes, R.F.5    Rossi-Bergmann, B.6
  • 31
    • 0343267814 scopus 로고    scopus 로고
    • Cohabitation of Leishmania amazo-nensis and Coxiella burnetii
    • Rabinovitch, M., and Veras, P. S. (1996). Cohabitation of Leishmania amazo-nensis and Coxiella burnetii. Trends Microbiol. 4, 158-161.
    • (1996) Trends Microbiol , vol.4 , pp. 158-161
    • Rabinovitch, M.1    Veras, P.S.2
  • 32
    • 77149132187 scopus 로고    scopus 로고
    • Induction of IFN-α/β enables Listeria monocytogenes to suppress macrophage activa-tion by IFN-γ
    • Rayamajhi, M., Humann, J., Pen-Heiter, K., Andreasen, K., and Lenz, L. L. (2010a). Induction of IFN-α/β enables Listeria monocytogenes to suppress macrophage activa-tion by IFN-γ. J. Exp. Med. 207, 327-337.
    • (2010) J. Exp. Med. , vol.207 , pp. 327-337
    • Rayamajhi, M.1    Humann, J.2    Pen-Heiter, K.3    Andreasen, K.4    Lenz, L.L.5
  • 33
    • 78349283456 scopus 로고    scopus 로고
    • Antagonistic crosstalk between type I and II interferons and increased host susceptibility to bacterial infec-tions
    • Rayamajhi, M., Humann, J., Kearney, S., Hill, K. K., and Lenz, L. L. (2010b). Antagonistic crosstalk between type I and II interferons and increased host susceptibility to bacterial infec-tions. Virulence 1, 418-422.
    • (2010) Virulence , vol.1 , pp. 418-422
    • Rayamajhi, M.1    Humann, J.2    Kearney, S.3    Hill, K.K.4    Lenz, L.L.5
  • 34
    • 78650680797 scopus 로고    scopus 로고
    • Fusion between Leish-mania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages
    • doi:10.1371/journal.pntd.0000905
    • Real,F.,Mortara,R.A.,and Rabinovitch, M. (2010). Fusion between Leish-mania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. PLoS Negl. Trop. Dis. 4, e905. doi:10.1371/journal.pntd.0000905
    • (2010) PLoS Negl. Trop. Dis. , vol.4
    • Real, F.1    Mortara, R.A.2    Rabinovitch, M.3
  • 35
    • 3042612202 scopus 로고    scopus 로고
    • Clinical and immunopathological spectrum of American cutaneous leishmania-sis with special reference to the disease in Amazonian Brazil: a review
    • Silveira, F. T., Lainson, R., and Cor-Bett, C. E. (2004). Clinical and immunopathological spectrum of American cutaneous leishmania-sis with special reference to the disease in Amazonian Brazil: a review. Mem. Inst. Oswaldo Cruz 99, 239-251.
    • (2004) Mem. Inst. Oswaldo Cruz , vol.99 , pp. 239-251
    • Silveira, F.T.1    Lainson, R.2    Cor-Bett, C.E.3
  • 36
    • 68249162071 scopus 로고    scopus 로고
    • Immunopath-ogenic competences of Leishma-nia (V ) braziliensis and L. (L.) amazonensis in American cutaneous leishmaniasis
    • Silveira, F. T., Lainson, R., De Castro Gomes, C. M., Laurenti, M. D., and Corbett, C. E. (2009). Immunopath-ogenic competences of Leishma-nia (V.) braziliensis and L. (L.) amazonensis in American cutaneous leishmaniasis. Parasite Immunol. 31, 423-431.
    • (2009) Parasite Immunol , vol.31 , pp. 423-431
    • Silveira, F.T.1    Lainson, R.2    De Castro Gomes, C.M.3    Laurenti, M.D.4    Corbett, C.E.5
  • 37
    • 44449089588 scopus 로고    scopus 로고
    • Modulation of den-dritic cell function by Leishma-nia parasites
    • Soong, L. (2008). Modulation of den-dritic cell function by Leishma-nia parasites. J. Immunol. 180, 4355-4360.
    • (2008) J. Immunol. , vol.180 , pp. 4355-4360
    • Soong, L.1
  • 39
    • 70049088449 scopus 로고    scopus 로고
    • Vibrio cholerae proteome-wide screen for immunostimulatory proteins identifies phosphatidylserine decar-boxylase as a novel Toll-like receptor 4 agonist
    • doi:10.1371/journal.ppat.1000556e1000556
    • Thanawastien, A., Montor, W. R., Labaer, J., Mekalanos, J. J., and Yoon, S. S. (2009). Vibrio cholerae proteome-wide screen for immunostimulatory proteins identifies phosphatidylserine decar-boxylase as a novel Toll-like receptor 4 agonist. PLoS Pathog. 5, e1000556. doi:10.1371/journal.ppat.1000556
    • (2009) PLoS Pathog , vol.5
    • Thanawastien, A.1    Montor, W.R.2    Labaer, J.3    Mekalanos, J.J.4    Yoon, S.S.5
  • 40
    • 67650080586 scopus 로고    scopus 로고
    • Distinct roles for MyD88 and Toll-like receptor 2 dur-ing Leishmania braziliensis infec-tion in mice
    • Vargas-Inchaustegui, D. A., Tai, W., Xin, L., Hogg, A. E., Corry, D. B., and Soong, L. (2009). Distinct roles for MyD88 and Toll-like receptor 2 dur-ing Leishmania braziliensis infec-tion in mice. Infect. Immun. 77, 2948-2956.
    • (2009) Infect. Immun. , vol.77 , pp. 2948-2956
    • Vargas-Inchaustegui, D.A.1    Tai, W.2    Xin, L.3    Hogg, A.E.4    Corry, D.B.5    Soong, L.6
  • 41
    • 47249165577 scopus 로고    scopus 로고
    • Leishmania braziliensis infection induces den-dritic cell activation, ISG15 tran-scription, and the generation of protective immune responses
    • Vargas-Inchaustegui, D. A., Xin, L., and Soong, L. (2008). Leishmania braziliensis infection induces den-dritic cell activation, ISG15 tran-scription, and the generation of protective immune responses. J. Immunol. 180, 7537-7545.
    • (2008) J. Immunol. , vol.180 , pp. 7537-7545
    • Vargas-Inchaustegui, D.A.1    Xin, L.2    Soong, L.3
  • 42
    • 34447332875 scopus 로고    scopus 로고
    • Effect of insulin-like growth factor-I on Leishmania amazonensis promastig-ote arginase activation and recip-rocal inhibition of NOS2 pathway in macrophage in vitro
    • Vendrame, C. M., Carvalho, M. D., Rios, F. J., Manuli, E. R., Petitto-Assis, F., and Goto, H. (2007). Effect of insulin-like growth factor-I on Leishmania amazonensis promastig-ote arginase activation and recip-rocal inhibition of NOS2 pathway in macrophage in vitro. Scand. J. Immunol. 66, 287-296.
    • (2007) Scand. J. Immunol. , vol.66 , pp. 287-296
    • Vendrame, C.M.1    Carvalho, M.D.2    Rios, F.J.3    Manuli, E.R.4    Petitto-Assis, F.5    Goto, H.6
  • 43
    • 34249898879 scopus 로고    scopus 로고
    • L-arginine and cationic amino acid transporter 2B regulate growth and survival of Leishmania amazonensis amastigotes in macrophages
    • Wanasen, N., MacLeod, C. L., Ellies, L. G., and Soong, L. (2007). L-arginine and cationic amino acid transporter 2B regulate growth and survival of Leishmania amazonensis amastigotes in macrophages. Infect. Immun. 75, 2802-2810.
    • (2007) Infect. Immun. , vol.75 , pp. 2802-2810
    • Wanasen, N.1    MacLeod, C.L.2    Ellies, L.G.3    Soong, L.4
  • 44
    • 77951899942 scopus 로고    scopus 로고
    • Apoptosis and apop-totic mimicry: the Leishmania con-nection
    • Wanderley, J. L., and Barcinski, M. A. (2010). Apoptosis and apop-totic mimicry: the Leishmania con-nection. Cell.Mol.LifeSci.67, 1653-1659.
    • (2010) Cell.Mol.LifeSci. 67 , pp. 1653-1659
    • Wanderley, J.L.1    Barcinski, M.A.2
  • 45
    • 31144454859 scopus 로고    scopus 로고
    • Mim-icry of apoptotic cells by expos-ing phosphatidylserine participates in the establishment of amastigotes of Leishmania (L) amazonensis in mammalian hosts
    • Wanderley, J. L., Moreira, M. E., Ben-Jamin, A., Bonomo, A. C., and Barcinski, M. A. (2006). Mim-icry of apoptotic cells by expos-ing phosphatidylserine participates in the establishment of amastigotes of Leishmania (L) amazonensis in mammalian hosts. J. Immunol. 176, 1834-1839.
    • (2006) J. Immunol. , vol.176 , pp. 1834-1839
    • Wanderley, J.L.1    Moreira, M.E.2    Ben-Jamin, A.3    Bonomo, A.C.4    Barcinski, M.A.5
  • 46
    • 79952306488 scopus 로고    scopus 로고
    • Differential microbicidal effects of human histone proteins H2A and H2B on Leishmania pro-mastigotes and amastigotes
    • Wang, Y., Chen, Y., Xin, L., Beverley, S. M., Carlsen, E. D., Popov, V., Chang, K. P., Wang, M., and Soong, L. (2011). Differential microbicidal effects of human histone proteins H2A and H2B on Leishmania pro-mastigotes and amastigotes. Infect. Immun. 79, 1124-1133.
    • (2011) Infect. Immun. , vol.79 , pp. 1124-1133
    • Wang, Y.1    Chen, Y.2    Xin, L.3    Beverley, S.M.4    Carlsen, E.D.5    Popov, V.6    Chang, K.P.7    Wang, M.8    Soong, L.9
  • 47
    • 61649127283 scopus 로고    scopus 로고
    • Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major
    • Williams, R. A.,Woods, K. L., Juliano, L., Mottram, J. C., and Coombs, G. H. (2009). Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major. Autophagy 5, 159-172.
    • (2009) Autophagy , vol.5 , pp. 159-172
    • Williams, R.A.1    Woods, K.L.2    Juliano, L.3    Mottram, J.C.4    Coombs, G.H.5
  • 48
    • 55449112725 scopus 로고    scopus 로고
    • Control of para-sitophorous vacuole expansion by LYST/Beige restricts the intracellular growth of Leishmania amazonen-sis
    • doi:10.1371/journal.ppat.1000179 e1000179
    • Wilson, J., Huynh, C., Kennedy, K. A., Ward, D. M., Kaplan, J., Aderem, A., and Andrews, N. W. (2008). Control of para-sitophorous vacuole expansion by LYST/Beige restricts the intracellular growth of Leishmania amazonen-sis. PLoS Pathog. 4, e1000179. doi:10.1371/journal.ppat.1000179
    • (2008) PLoS Pathog , vol.4
    • Wilson, J.1    Huynh, C.2    Kennedy, K.A.3    Ward, D.M.4    Kaplan, J.5    Aderem, A.6    Andrews, N.W.7
  • 50
    • 77953633983 scopus 로고    scopus 로고
    • Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites
    • Xin, L., Vargas-Inchaustegui, D. A., Raimer, S. S., Kelly, B. C., Hu, J., Zhu, L.,Sun,J.,and Soong,L. (2010). Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J. Immunol. 184, 7047-7056.
    • (2010) J. Immunol. , vol.184 , pp. 7047-7056
    • Xin, L.1    Vargas-Inchaustegui, D.A.2    Raimer, S.S.3    Kelly, B.C.4    Hu, J.5    Zhu, L.6    Sun, J.7    Soong, L.8
  • 51
    • 79751483819 scopus 로고    scopus 로고
    • + T-cell activation rather than TCR diversity determines the Soong Subversion of host defense by L. amazonensis outcome of Leishmania infection in mice
    • + T-cell activation rather than TCR diversity determines the Soong Subversion of host defense by L. amazonensis outcome of Leishmania infection in mice. Parasite Immunol. 33, 170-180.
    • (2011) Parasite Immunol , vol.33 , pp. 170-180
    • Xin, L.1    Wanderley, J.L.2    Wang, Y.3    Vargas-Inchaustegui, D.A.4    Soong, L.5
  • 52
    • 79961118829 scopus 로고    scopus 로고
    • Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host
    • Xu, W., Xin, L., Soong, L., and Zhang, K. (2011). Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host. Infect. Immun. 79, 3377-3387.
    • (2011) Infect. Immun. , vol.79 , pp. 3377-3387
    • Xu, W.1    Xin, L.2    Soong, L.3    Zhang, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.