Role of heat shock protein 70 in innate alloimmunity

Frontiers in Immunology

Volumn 2, Issue JAN, 2012, Pages

  Land, Walter G ^a  

^a German Academy of Transplantation Medicine   (Germany)

Author keywords

DAMPs; HSP72; Injury hypothesis; Innate alloimmunity

Indexed keywords

EID: 84874102568     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2011.00089     Document Type: Article

References (47)

1. Arbogast, H., Arbogast, S., Fertmann, J., and Land, W. (2002). Expression of heat shock proteins in cadaveric human renal allografts - a role in activation of innate immunity? Transplantation 74(Suppl.), 266.
2. Bauernfeind, F., Ablasser, A., Bartok, E., Kim, S., Schmid-Burgk, J., Cavlar, T., and Hornung, V. (2011). Inflamma-somes: current understanding and open questions. Cell. Mol. Life Sci. 68, 765-783.
3. Bethke, K., Staib, F., Distler, M., Schmitt, U., Jonuleit, H., Enk, A. H., Galle, P. R., and Heike, M. (2002). Different efficiency of heat shock proteins (HSP) to activate human monocytes and dendritic cells: superiority of HSP60. J. Immunol. 169, 6141-6148.
4. Beutler, B. (2007). Neo-ligands for innate immune receptors and the etiology of sterile inflammatory disease. Immunol. Rev. 220, 113-128.
5. Binder, R. J. (2006). Heat shock protein vaccines: from bench to bedside. Int. Rev. Immunol. 25, 353-375.
6. Borges, T. J., Porto, B. N., Teixeira, C. A., Rodrigues, M., Machado, E D., Ornaghi, A. P., de Souza, A. P., Maito, F., Pavanelli, W. R., Silva, J. S., and Bonorino, C. (2010). Prolonged survival of allografts induced by mycobacterial HSP70 is dependent on CD4CD25 regulatory T cells. PLoS ONE 5, e14264. doi: 10.1371/journal.pone.00 14264.
7. Bours, M. J., Dagnelie, P. C., Giuliani, A. L., Wesselius, A., and Di Virgilio, E (2011). P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation. Front. Biosci. (Schol. Ed). 3, 1443-1456.
8. Castelli, C., Ciupitu, A. M., Rini, F., Rivoltini, L., Mazzocchi, A., Kiessling, R., and Parmiani, G. (2001). Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells. Cancer Res. 61, 222-227.
9. Chen, G. Y., and Nuñez, G. (2010). Sterile inflammation: sensing and reacting to damage. Nat. Rev. Immunol. 10, 826-837.
10. Fang, H., Wu, Y., Huang, X., Wang, W., Ang, B., Cao, X., and Wan, T. (2011). Toll-like receptor 4 (TLR4) is essential for Hsp70-like protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response. J. Biol. Chem. 286, 30393-30400.
11. Fu, H., Song, S., Liu, F., Ni, Z., Tang, Y., Shen, X., Xiao, L., Ding, G., and Wang, Q. (2009). Dendritic cells transduced withSOCS1 geneexhibit regulatory DC properties and prolong allograft survival. Cell. Mol. Immunol. 6, 87-95.
12. Iyer, S., Pulskensc, W., Sadler, J., Butter, L. M., Teske, G. J., Ulland, T. K., Eisenbarth, S. C., Florquin, S., Flavell, R. A., Leemans, J. C., and Sutterwala, E S. (2009). Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflam-masome. Proc. Nat. Acad. Sci. U.S.A. 106, 20388-20393.
13. Jaeschke, H. (2011). Reactive oxygen and mechanisms of inflammatory liver injury: present concepts. J. Gastroenterol. Hepatol. 26(Suppl. 1), 173-179.
14. Jo, S. K., Ko, G. J., Boo, C. S., Cho, W. Y., and Kim, H. K. (2006). Heat preconditioning attenuates renal injury in ischemic ARF in rats: role of heat-shock protein 70 on NF-kappaB-mediated inflammation and on tubular cell injury. J. Am. Soc. Nephrol. 17, 3082-3092.
15. Jurewicz, M., Takakura, A., Augello, A., Naini, S. M., Ichimura, T., Zandi-Nejad, K., and Abdi, R. (2010). Ischemic injury enhances dendritic cell immunogenicity via TLR4 and NF-kappa B activation. J. Immunol. 184, 2939-2948.
16. Kaczorowski, D. J., Nakao, A., Val-labhaneni, R., Mollen, K. P., Sug-imoto, R., Kohmoto, J., Zucker-braun, B. S., McCurry, K. R., and Billiar, T. R. (2009). Mechanisms of Toll-like receptor 4 (TLR4) mediated inflammation after cold ischemia/reperfusion in the heart. Transplantation 87, 1455-1463.
17. Kaminska, D., Koscielska-Kasprzak, K., Drulis-Fajdasz, D., Halon, A., Polak, W., Chudoba, P., Janczak, D., Mazanowska, O., Patrzalek, D., and Klinger, M. (2011). Kidney ischemic injury genes expressed after donor brain death are predictive for the outcome of kidney transplantation. Transplant. Proc. 43, 2891-2894.
18. Karikó, K., Weissman, D., and Welsh, E A. (2004). Inhibition of Toll-like receptor and cytokine signaling - a unifying theme in ischemic tolerance. J. Cereb. Blood Flow Metab. 24, 1288-1304.
19. Kis-Toth, K., Szanto, A., Thai, T. H., and Tsokos, G. C. (2011). Cytoso-lic DNA-activated human dendritic cells are potent activators of the adaptive immune response. J. Immunol. 187, 1222-1234.
20. Klune, J. R., and Tsung, A. (2010). Molecular biology of liver ischemia/reperfusion injury: established mechanisms and recent advancements. Surg. Clin. North Am. 90, 665-677.
21. Koide, T., Iinuma, H., and Fukushima, R. (2009). Efficient CTL productivity of modified fusion cells by increase of heat shock protein 70. Oncol. Rep. 21, 737-746.
22. Krüger, B., Krick, S., Dhillon, N., Lerner, S. M., Ames, S., Bromberg, J. S., Lin, M., Walsh, L., Vella, J., Fischereder, M., Krämer, B. K., Colvin, R. B., Heeger, P. S., Murphy, B. T., and Schröppel, B. (2009). Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc. Natl. Acad. Sci. U.S.A. 106, 3390-3395.
23. Kumar, H., Kawai, T., and Akira, S. (2011). Pathogen recognition by the innate immune system. Int. Rev. Immunol. 30, 16-34.
24. Kuppner, M. C., Gastpar, R., Gelwer, S., Nössner, E., Ochmann, O., Scharner, A., and Issels, R. D. (2001). The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors. Eur. I Immunol. 31, 1602-1609.
25. Land, W (2002). Postischemic reperfusion injury to allografts - a case for "innate immunity"? Eur. Surg. Res. 34, 160-169.
26. Land, W (2003a). Allograft injury mediated by reactive oxygen species: from conserved proteins of Drosophila to acute and chronic rejection of human transplants. Part III: interaction of (oxidative) stress-induced heat shock proteins with Toll-like receptor-bearing cells of innate immunity and its consequences for the development of acute and chronic allograft rejection. Transplant. Rev. 17, 67-86.
27. Land, W. (2003b). Allograft injury mediated by reactive oxygen species: from conserved proteins of Drosophila to acute and chronic rejection of human transplants. Part II: role of reactive oxygen species in the induction of the heat shock response as a regulator of innate immunity. Transplant. Rev. 17, 31-44.
28. Land, W., Schneeberger, H., Schleib-ner, S., Illner, W. D., Abendroth, D., Rutili, G., Arfors, K. E., and Messmer, K. (1994). The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants. Transplantation 57, 211-217.
29. Land, W. G. (2011a). Emerging role of innate immunity in organ transplantation. Part I: evolution of innate immunity and oxidative allograft injury. Transplant. Rev. (Orlando). doi: 10.1016/j.trre.2011.05.001. [Epub ahead of print].
30. Land, W. G. (2011b). Emerging role of innate immunity in organ transplantation. Part II: Potential of DAMPs to generate immunostimulatory dendritic cells. Transplant. Rev. (Orlando). doi: 10.1016/jtrre.2011.02.003. [Epub ahead of print].
31. Land, W. G. (2011c). Emerging role of innate immunity in organ transplantation. Part III: the quest for transplant tolerance via prevention of oxidative allograft injury and its consequences. Transplant. Rev. (Orlando). doi: 10.1016/j.trre.2011.07.001. [Epub ahead of print].
32. Land, W. G. (2011d). "Negative regulation of TLR-signaling pathways, " in Innate Alloimmunity, Part I: Innate Immunity and Host Defence, ed. W. G. Land (Lengerich: Baskent University, Pabst Science Publishers), 267-285.
33. Land, W. G. (2011e). "Oxidative injury-induced, damage-associated molecular pattern molecules and their pattern recognition receptors, " in Innate Alloimmunity, Part II: Innate Immunity and Allograft Rejection, ed. W. G. Land (Lengerich: Baskent University, Pabst Science Publishers), 229-337.
34. Maldonado, R. A., and von Andrian, U. H. (2010). How tolerogenic dendritic cells induce regulatory T cells. Adv. Immunol. 108, 111-165.
35. Manfredi, A. A., Capobianco, A., Bianchi, M. E., and Rovere-Querini, P. (2009). Regulation of dendritic-and T-cell fate by injury-associated endogenous signals. Crit. Rev. Immunol. 29, 69-86.
36. Matzinger, P. (1994). Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12, 991-1045.
37. Milani, V., Noessner, E., Ghose, S., Kup-pner, M., Ahrens, B., Scharner, A., Gastpar, R., and Issels, R. D. (2002). Heat shock protein 70 role in antigen presentation and immune stimulation. Int. J. Hyperthermia 18, 563.
38. Mun, H. S., Aosai, F., Norose, K., Piao, L. X., Fang, H., Akira, S., and Yano, A. (2005). Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derivedheat shock protein 70. Infect. Immun. 73, 4634-4642.
39. Oh, K. H., Kim, J. Y., Kim, D., Lee, E. M., Oh, H. Y., Seo, J. S., Han, J. S., Kim, S., Lee, J.S., andAhn, C. (2004). Targeted gene disruption of the heat shock protein 72 gene (hsp70.1) in the donor tissue is associated with a prolonged rejection-free survival in the murine skin allograft model. Transpl. Immunol. 13, 273-281.
40. Posselt, G., Schwarz, H., Duschl, A., and Horejs-Hoeck, J. (2011). Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells. J. Immunol. 187, 2875-2884.
41. Sano, T., Izuishi, K., Hossain, M. A., Inoue, T., Kakinoki, K., Hagiike, M., Okano, K., Masaki, T., and Suzuki, Y. (2011). Hepatic preconditioning using lipopolysaccharide: association with specific negative regulators of the Toll-like receptor 4 signaling pathway. Transplantation 91, 1082-1089.
42. Schröder, K., Zhou, R., and Tschopp, J. (2010). The NLRP3 inflamma-some: a sensor for metabolic danger? Science 327, 296-300.
43. Srivastava, P. (2002). Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. 20, 395-425.
44. Stocki, P., Morris, N. J., Preisinger, C., Wang, X. N., Kolch, W., Multhoff, G., and Dickinson, A.M. (2010). Identification of potential HLA class I and class II epitope precursors associated with heat shock protein 70 (HSPA). Cell Stress Chaperones 15, 729-741.
45. Ueda, G., Tamura, Y., Hirai, I., Kamiguchi, K., Ichimiya, S., Torigoe, T., Hiratsuka, H., Sunakawa, H., and Sato, N. (2004). Tumor-derived heat shock protein 70-pulsed dendritic cells elicit tumor-specific cytotoxic T lymphocytes (CTLs) and tumor immunity. CancerSci. 95, 248-253.
46. van Eden, W., van der Zee, R., and Prakken, B. (2005). Heat-shock proteins induce T cell regulation of chronic inflammation. Nat. Rev. Immunol. 5, 318-330.
47. Yanai, H., Ban, T., and Taniguchi, T. (2011). Essential role of high-mobility group box proteins in nucleic acid-mediated innate immune responses. J. Intern. Med. 270, 301-308.