HGF stimulation of Rac1 signaling enhances pharmacological correction of the most prevalent cystic fibrosis mutant F508del-CFTR

ACS Chemical Biology

Volumn 8, Issue 2, 2013, Pages 432-442

  Moniz, Sónia ^a,b   Sousa, Marisa ^a,b   Moraes, Bruno José ^a,b   Mendes, Ana Isabel ^a,b   Palma, Marta ^b   Barreto, Celeste ^c   Fragata, José I ^d   Amaral, Margarida D ^a,b   Matos, Paulo ^a,b  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b UNIVERSITY OF LISBON   (Portugal)

^c HOSPITAL DE SANTA MARIA   (Portugal)

^d HOSPITAL DE SANTA MARTA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EZRIN; F ACTIN; LUMACAFTOR; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SCATTER FACTOR; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR DELTA F508; RAC1 PROTEIN, HUMAN;

ACTIN FILAMENT; ARTICLE; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; MUCOCILIARY CLEARANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CHEMICAL STRUCTURE; GENETICS; METABOLISM; MOUSE; MUTATION;

ANIMALS; CELLS, CULTURED; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HEPATOCYTE GROWTH FACTOR; HUMANS; MICE; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; MUTATION; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84874094442     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300484r     Document Type: Article

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