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Volumn 26, Issue 2, 2013, Pages 203-212

Protein synthesis inhibition and oxidative stress induced by cylindrospermopsin elicit apoptosis in primary rat hepatocytes

Author keywords

[No Author keywords available]

Indexed keywords

CYLINDROSPERMOPSIN; REACTIVE OXYGEN METABOLITE;

EID: 84874080781     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx3003438     Document Type: Article
Times cited : (48)

References (34)
  • 1
    • 77952515545 scopus 로고    scopus 로고
    • Cylindrospermopsin: A decade of progress on bioaccumulation research
    • Kinnear, S. (2010) Cylindrospermopsin: a decade of progress on bioaccumulation research Mar. Drugs 8, 542-564
    • (2010) Mar. Drugs , vol.8 , pp. 542-564
    • Kinnear, S.1
  • 2
    • 0019191617 scopus 로고
    • Palm Island mystery disease
    • Byth, S. (1980) Palm Island mystery disease Med. J. Aust. 2 (40) 42
    • (1980) Med. J. Aust. , vol.2 , Issue.40 , pp. 42
    • Byth, S.1
  • 4
    • 0038508656 scopus 로고    scopus 로고
    • The Palm Island mystery disease 20 years on: A review of research on the cyanotoxin cylindrospermopsin
    • DOI 10.1002/tox.10103
    • Griffiths, D. J. and Saker, M. L. (2003) The Palm Island mystery disease 20 years on: a review of research on the cyanotoxin cylindrospermopsin Environ. Toxicol. 18, 78-93 (Pubitemid 44793764)
    • (2003) Environmental Toxicology , vol.18 , Issue.2 , pp. 78-93
    • Griffiths, D.J.1    Saker, M.L.2
  • 5
    • 0022402504 scopus 로고
    • Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir
    • Hawkins, P. R., Runnegar, M. T., Jackson, A. R., and Falconer, I. R. (1985) Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir Appl. Environ. Microbiol. 50, 1292-1295 (Pubitemid 16193446)
    • (1985) Applied and Environmental Microbiology , vol.50 , Issue.5 , pp. 1292-1295
    • Hawkins, P.R.1    Runnegar, M.T.C.2    Jackson, A.R.B.3    Falconer, I.R.4
  • 6
    • 0038706470 scopus 로고    scopus 로고
    • First report and toxicological assessment of the cyanobacterium Cylindrospermopsis raciborskii from Portuguese freshwaters
    • DOI 10.1016/S0147-6513(02)00043-X
    • Saker, M. L., Nogueira, I. C., Vasconcelos, V. M., Neilan, B. A., Eaglesham, G. K., and Pereira, P. (2003) First report and toxicological assessment of the cyanobacterium Cylindrospermopsis raciborskii from Portuguese freshwaters Ecotoxicol. Environ. Saf. 55, 243-250 (Pubitemid 36555411)
    • (2003) Ecotoxicology and Environmental Safety , vol.55 , Issue.2 , pp. 243-250
    • Saker, M.L.1    Nogueira, I.C.G.2    Vasconcelos, V.M.3    Neilan, B.A.4    Eaglesham, G.K.5    Pereira, P.6
  • 7
    • 0032152219 scopus 로고    scopus 로고
    • Cyanobacterium Cylindrospermopsis raciborskii as a probable cause of death in cattle in northern Queensland
    • Thomas, A. D., Saker, M. L., Norton, J. H., and Olsen, R. D. (1998) Cyanobacterium Cylindrospermopsis raciborskii as a probable cause of death in cattle in northern Queensland Aust. Vet. J. 76, 592-594
    • (1998) Aust. Vet. J. , vol.76 , pp. 592-594
    • Thomas, A.D.1    Saker, M.L.2    Norton, J.H.3    Olsen, R.D.4
  • 8
    • 80052850108 scopus 로고
    • Cylindrospermopsin: A potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii
    • Ohtani, I., Moore, R. E., and Runnegar, M. T. C. (1992) Cylindrospermopsin: a potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii J. Am. Chem. Soc. 114, 7941-7942
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 7941-7942
    • Ohtani, I.1    Moore, R.E.2    Runnegar, M.T.C.3
  • 9
    • 0028158344 scopus 로고
    • Isolation of cylindrospermopsin from a cyanobacterium Umezakia natans and its screening method
    • DOI 10.1016/0041-0101(94)90023-X
    • Harada, K. I., Ohtani, I., Iwamoto, K., Suzuki, M., Watanabe, M. F., Watanabe, M., and Terao, K. (1994) Isolation of cylindrospermopsin from a cyanobacterium Umezakia natans and its screening method Toxicon 32, 73-84 (Pubitemid 24047963)
    • (1994) Toxicon , vol.32 , Issue.1 , pp. 73-84
    • Harada, K.-I.1    Ohtani, I.2    Iwamoto, K.3    Suzuki, M.4    Watanabe, M.F.5    Watanabe, M.6    Terao, K.7
  • 10
    • 79955104001 scopus 로고    scopus 로고
    • Genotoxicity and potential carcinogenicity of cyanobacterial toxins: A review
    • Zegura, B., Straser, A., and Filipic, M. (2011) Genotoxicity and potential carcinogenicity of cyanobacterial toxins: a review Mutat. Res. 727, 16-41
    • (2011) Mutat. Res. , vol.727 , pp. 16-41
    • Zegura, B.1    Straser, A.2    Filipic, M.3
  • 12
    • 33746701372 scopus 로고    scopus 로고
    • Cyanobacterial (blue-green algal) toxins in water supplies: Cylindrospermopsins
    • DOI 10.1002/tox.20194
    • Falconer, I. R. and Humpage, A. R. (2006) Cyanobacterial (blue-green algal) toxins in water supplies: Cylindrospermopsins Environ. Toxicol. 21, 299-304 (Pubitemid 44167699)
    • (2006) Environmental Toxicology , vol.21 , Issue.4 , pp. 299-304
    • Falconer, I.R.1    Humpage, A.R.2
  • 13
    • 0033980562 scopus 로고    scopus 로고
    • Cylindrospermopsin, a cyanobacterial alkaloid: Evaluation of its toxicologic activity
    • DOI 10.1097/00007691-200002000-00019
    • Shaw, G. R., Seawright, A. A., Moore, M. R., and Lam, P. K. (2000) Cylindrospermopsin, a cyanobacterial alkaloid: evaluation of its toxicologic activity Ther. Drug Monit. 22, 89-92 (Pubitemid 30083105)
    • (2000) Therapeutic Drug Monitoring , vol.22 , Issue.1 , pp. 89-92
    • Shaw, G.R.1    Seawright, A.A.2    Moore, M.R.3    Lam, P.K.S.4
  • 14
    • 84859742065 scopus 로고    scopus 로고
    • Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection
    • Bazin, E., Huet, S., Jarry, G., Hegarat, L. L., Munday, J. S., Humpage, A. R., and Fessard, V. (2010) Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection Environ. Toxicol. 27, 277-284
    • (2010) Environ. Toxicol. , vol.27 , pp. 277-284
    • Bazin, E.1    Huet, S.2    Jarry, G.3    Hegarat, L.L.4    Munday, J.S.5    Humpage, A.R.6    Fessard, V.7
  • 15
    • 0034695122 scopus 로고    scopus 로고
    • Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin
    • Humpage, A. R., Fenech, M., Thomas, P., and Falconer, I. R. (2000) Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin Mutat. Res., Genet. Toxicol. Environ. Mutagen. 472, 155-161
    • (2000) Mutat. Res., Genet. Toxicol. Environ. Mutagen. , vol.472 , pp. 155-161
    • Humpage, A.R.1    Fenech, M.2    Thomas, P.3    Falconer, I.R.4
  • 17
    • 77951653083 scopus 로고    scopus 로고
    • Morphological cell transformation of Syrian hamster embryo (SHE) cells by the cyanotoxin, cylindrospermopsin
    • Maire, M. A., Bazin, E., Fessard, V., Rast, C., Humpage, A. R., and Vasseur, P. (2010) Morphological cell transformation of Syrian hamster embryo (SHE) cells by the cyanotoxin, cylindrospermopsin Toxicon 55, 1317-1322
    • (2010) Toxicon , vol.55 , pp. 1317-1322
    • Maire, M.A.1    Bazin, E.2    Fessard, V.3    Rast, C.4    Humpage, A.R.5    Vasseur, P.6
  • 18
    • 82355182748 scopus 로고    scopus 로고
    • Genotoxic effects of the cyanobacterial hepatotoxin cylindrospermopsin in the HepG2 cell line
    • Straser, A., Filipic, M., and Zegura, B. (2011) Genotoxic effects of the cyanobacterial hepatotoxin cylindrospermopsin in the HepG2 cell line Arch. Toxicol. 85, 1617-1626
    • (2011) Arch. Toxicol. , vol.85 , pp. 1617-1626
    • Straser, A.1    Filipic, M.2    Zegura, B.3
  • 19
    • 0035072467 scopus 로고    scopus 로고
    • Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue-green alga cylindrospermopsis raciborskil containing the toxin cylindrospermopsin
    • DOI 10.1002/tox.1024
    • Falconer, I. R. and Humpage, A. R. (2001) Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue-green alga cylindrospermopsis raciborskii containing the toxin cylindrospermopsin Environ. Toxicol. 16, 192-195 (Pubitemid 32294157)
    • (2001) Environmental Toxicology , vol.16 , Issue.2 , pp. 192-195
    • Falconer, I.R.1    Humpage, A.R.2
  • 20
    • 0033034115 scopus 로고    scopus 로고
    • Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice
    • Falconer, I. R., Hardy, S. J., Humpage, A. R., Froscio, S. M., Tozer, G. J., and Hawkins, P. R. (1999) Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice Environ. Toxicol. 14, 143-150
    • (1999) Environ. Toxicol. , vol.14 , pp. 143-150
    • Falconer, I.R.1    Hardy, S.J.2    Humpage, A.R.3    Froscio, S.M.4    Tozer, G.J.5    Hawkins, P.R.6
  • 21
    • 0028200062 scopus 로고
    • Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans
    • DOI 10.1016/0041-0101(94)90008-6
    • Terao, K., Ohmori, S., Igarashi, K., Ohtani, I., Watanabe, M. F., Harada, K. I., Ito, E., and Watanabe, M. (1994) Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans Toxicon 32, 833-843 (Pubitemid 24193482)
    • (1994) Toxicon , vol.32 , Issue.7 , pp. 833-843
    • Terao, K.1    Ohmori, S.2    Igarashi, K.3    Ohtani, I.4    Watanabe, M.F.5    Harada, K.I.6    Ito, E.7    Watanabe, M.8
  • 22
    • 0028853288 scopus 로고
    • Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
    • Runnegar, M. T., Kong, S. M., Zhong, Y. Z., and Lu, S. C. (1995) Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes Biochem. Pharmacol. 49, 219-225
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 219-225
    • Runnegar, M.T.1    Kong, S.M.2    Zhong, Y.Z.3    Lu, S.C.4
  • 23
    • 0042978772 scopus 로고    scopus 로고
    • Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes
    • DOI 10.1002/tox.10121
    • Froscio, S. M., Humpage, A. R., Burcham, P. C., and Falconer, I. R. (2003) Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes Environ. Toxicol. 18, 243-251 (Pubitemid 37009916)
    • (2003) Environmental Toxicology , vol.18 , Issue.4 , pp. 243-251
    • Froscio, S.M.1    Humpage, A.R.2    Burcham, P.C.3    Falconer, I.R.4
  • 24
    • 0036094367 scopus 로고    scopus 로고
    • In vitro hepatotoxicity of the cyanobacterial alkaloid cyclindrospermopsin and related synthetic analogues
    • DOI 10.1093/toxsci/67.1.81
    • Runnegar, M. T., Xie, C., Snider, B. B., Wallace, G. A., Weinreb, S. M., and Kuhlenkamp, J. (2002) In vitro hepatotoxicity of the cyanobacterial alkaloid cylindrospermopsin and related synthetic analogues Toxicol. Sci. 67, 81-87 (Pubitemid 34520812)
    • (2002) Toxicological Sciences , vol.67 , Issue.1 , pp. 81-87
    • Runnegar, M.T.1    Xie, C.2    Snider, B.B.3    Wallace, G.A.4    Weinreb, S.M.5    Kuhlenkamp, J.6
  • 25
    • 84856658679 scopus 로고    scopus 로고
    • Biochemical and pathological toxic effects induced by the cyanotoxin cylindrospermopsin on the human cell line Caco-2
    • Gutierrez-Praena, D., Pichardo, S., Jos, A., Moreno, F. J., and Camean, A. M. (2012) Biochemical and pathological toxic effects induced by the cyanotoxin cylindrospermopsin on the human cell line Caco-2 Water Res. 46, 1566-1575
    • (2012) Water Res. , vol.46 , pp. 1566-1575
    • Gutierrez-Praena, D.1    Pichardo, S.2    Jos, A.3    Moreno, F.J.4    Camean, A.M.5
  • 26
    • 0036027412 scopus 로고    scopus 로고
    • Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes
    • DOI 10.1016/S0041-0101(01)00228-8, PII S0041010101002288
    • Chong, M. W., Wong, B. S., Lam, P. K., Shaw, G. R., and Seawright, A. A. (2002) Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes Toxicon 40, 205-211 (Pubitemid 33016550)
    • (2002) Toxicon , vol.40 , Issue.2 , pp. 205-211
    • Chong, M.W.K.1    Wong, B.S.F.2    Lam, P.K.S.3    Shaw, G.R.4    Seawright, A.A.5
  • 27
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen, P. O. (1976) Preparation of isolated rat liver cells Methods Cell Biol. 13, 29-83
    • (1976) Methods Cell Biol. , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 28
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72, 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 30
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno, G. and Joris, I. (1995) Apoptosis, oncosis, and necrosis. An overview of cell death Am. J. Pathol. 146, 3-15
    • (1995) Am. J. Pathol. , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 31
    • 77950351190 scopus 로고    scopus 로고
    • Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco-2 and HepaRG
    • Bazin, E., Mourot, A., Humpage, A. R., and Fessard, V. (2010) Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco-2 and HepaRG Environ. Mol. Mutagen. 51, 251-259
    • (2010) Environ. Mol. Mutagen. , vol.51 , pp. 251-259
    • Bazin, E.1    Mourot, A.2    Humpage, A.R.3    Fessard, V.4
  • 32
    • 36749081135 scopus 로고    scopus 로고
    • Resveratrol as an antioxidant and pro-oxidant agent: Mechanisms and clinical implications
    • DOI 10.1042/BST0351156
    • de la Lastra, C. A. and Villegas, I. (2007) Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications Biochem. Soc. Trans. 35, 1156-1160 (Pubitemid 350206449)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1156-1160
    • Alarcon De La Lastra, C.1    Villegas, I.2
  • 33
    • 54049145855 scopus 로고    scopus 로고
    • Resveratrol protects primary rat hepatocytes against necrosis induced by reactive oxygen species
    • Rubiolo, J. A. and Vega, F. V. (2008) Resveratrol protects primary rat hepatocytes against necrosis induced by reactive oxygen species Biomed. Pharmacother. 62, 606-612
    • (2008) Biomed. Pharmacother. , vol.62 , pp. 606-612
    • Rubiolo, J.A.1    Vega, F.V.2


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