-
2
-
-
77950351190
-
Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two 1 human cell lines: Caco-2 and HepaRG
-
in press.
-
Bazin, E., Mourot, A., Humpage, A.R., Fessard V. Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two 1 human cell lines: Caco-2 and HepaRG, Environ. Mol. Mutagen, in press.
-
Environ. Mol. Mutagen
-
-
Bazin, E.1
Mourot, A.2
Humpage, A.R.3
Fessard, V.4
-
3
-
-
0035936887
-
Uracil moiety is required for toxicity of the cyanobacterial hepatotoxin cylindrospermopsin
-
Banker R., Carmeli S., Werman M., Teltsch B., Porat R., Sukenik A. Uracil moiety is required for toxicity of the cyanobacterial hepatotoxin cylindrospermopsin. J. Toxicol. Environ. Health Part A. 2001, 62(4):281-288.
-
(2001)
J. Toxicol. Environ. Health Part A.
, vol.62
, Issue.4
, pp. 281-288
-
-
Banker, R.1
Carmeli, S.2
Werman, M.3
Teltsch, B.4
Porat, R.5
Sukenik, A.6
-
4
-
-
0001283359
-
In vitro cell transformation with chemical carcinogens
-
Berwald Y., Sachs L. In vitro cell transformation with chemical carcinogens. Nature 1963, 200:1182-1184.
-
(1963)
Nature
, vol.200
, pp. 1182-1184
-
-
Berwald, Y.1
Sachs, L.2
-
5
-
-
0013808158
-
In vitro transformation of normal cells to tumor cells by carcinogenic hydrocarbons
-
Berwald Y., Sachs L. In vitro transformation of normal cells to tumor cells by carcinogenic hydrocarbons. J. Natl. Cancer Inst. 1965, 35:641-661.
-
(1965)
J. Natl. Cancer Inst.
, vol.35
, pp. 641-661
-
-
Berwald, Y.1
Sachs, L.2
-
6
-
-
0028559881
-
Chlorothalonil promotes morphological transformation in hamster embryo cells but does not inhibit GAP junctional intercellular communication either in SHE cells or in the V79 cell line
-
Bessi H., Rast C., Nguyen-Ba G., Vasseur P. Chlorothalonil promotes morphological transformation in hamster embryo cells but does not inhibit GAP junctional intercellular communication either in SHE cells or in the V79 cell line. Cancer J. 1994, 7:248-253.
-
(1994)
Cancer J.
, vol.7
, pp. 248-253
-
-
Bessi, H.1
Rast, C.2
Nguyen-Ba, G.3
Vasseur, P.4
-
7
-
-
0034741820
-
Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins
-
Carmichael W.W., Azevedo S.M., An J.S., Molica R.J., Jochimsen E.M., Lau S., Rinehart K.L., Shaw G.R., Eaglesham G. Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins. Environ. Health Persp. 2001, 109:663-668.
-
(2001)
Environ. Health Persp.
, vol.109
, pp. 663-668
-
-
Carmichael, W.W.1
Azevedo, S.M.2
An, J.S.3
Molica, R.J.4
Jochimsen, E.M.5
Lau, S.6
Rinehart, K.L.7
Shaw, G.R.8
Eaglesham, G.9
-
8
-
-
0036027412
-
Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes
-
Chong M.W., Wong B.S., Lam P.K., Shaw G.R., Seawright A.A. Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes. Toxicon 2002, 40(2):205-211.
-
(2002)
Toxicon
, vol.40
, Issue.2
, pp. 205-211
-
-
Chong, M.W.1
Wong, B.S.2
Lam, P.K.3
Shaw, G.R.4
Seawright, A.A.5
-
9
-
-
0032716592
-
Cell transformation assay as predictors of human carcinogenicity, the reports and recommendations of ECVAM, workshop 39
-
Combes R., Balls M., Curren R.D., Fischbach M., Fusenig N., Kirkland D., Lasne C., Landolph J., LeBoeuf R.A., Marquardt H., McCormick J., Müller L., Rivedal E., Sabbioni E., Tanaka N., Vasseur P., Yamasaki H. Cell transformation assay as predictors of human carcinogenicity, the reports and recommendations of ECVAM, workshop 39. Altern. Lab. Anim. 1999, 27:745-767.
-
(1999)
Altern. Lab. Anim.
, vol.27
, pp. 745-767
-
-
Combes, R.1
Balls, M.2
Curren, R.D.3
Fischbach, M.4
Fusenig, N.5
Kirkland, D.6
Lasne, C.7
Landolph, J.8
LeBoeuf, R.A.9
Marquardt, H.10
McCormick, J.11
Müller, L.12
Rivedal, E.13
Sabbioni, E.14
Tanaka, N.15
Vasseur, P.16
Yamasaki, H.17
-
10
-
-
0015110824
-
Morphological, oncogenic, and karyological characteristics of Syrian hamster embryo cells transformed in vitro by carcinogenic polycyclic hydrocarbons
-
DiPaolo J.A., Nelson R.L., Donovan P.J. Morphological, oncogenic, and karyological characteristics of Syrian hamster embryo cells transformed in vitro by carcinogenic polycyclic hydrocarbons. Cancer Res. 1971, 31(8):1118-1127.
-
(1971)
Cancer Res.
, vol.31
, Issue.8
, pp. 1118-1127
-
-
DiPaolo, J.A.1
Nelson, R.L.2
Donovan, P.J.3
-
11
-
-
0033841646
-
Cytotoxic and transforming effects of silica particles with different surface properties in Syrian hamster embryo (SHE) cells
-
Elias Z., Poirot O., Daniere M.C., Terzetti F., Marande A.M., Dzwigaj S., Pezerat H., Fenoglio I., Fubini B. Cytotoxic and transforming effects of silica particles with different surface properties in Syrian hamster embryo (SHE) cells. Toxicol. In Vitro 1989, 14:409-422.
-
(1989)
Toxicol. In Vitro
, vol.14
, pp. 409-422
-
-
Elias, Z.1
Poirot, O.2
Daniere, M.C.3
Terzetti, F.4
Marande, A.M.5
Dzwigaj, S.6
Pezerat, H.7
Fenoglio, I.8
Fubini, B.9
-
12
-
-
0033034115
-
Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice
-
Falconer I.R., Hardy S.J., Humpage A.R., Froscio S.M., Tozer G.J., Hawkins P.R. Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice. Environ. Toxicol. 1999, 14:143-150.
-
(1999)
Environ. Toxicol.
, vol.14
, pp. 143-150
-
-
Falconer, I.R.1
Hardy, S.J.2
Humpage, A.R.3
Froscio, S.M.4
Tozer, G.J.5
Hawkins, P.R.6
-
13
-
-
0035072467
-
Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue-green alga Cylindrospermopsis raciborskii containing the toxin cylindrospermopsin
-
Falconer I.R., Humpage A.R. Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue-green alga Cylindrospermopsis raciborskii containing the toxin cylindrospermopsin. Environ. Toxicol 2001, 16:192-195.
-
(2001)
Environ. Toxicol
, vol.16
, pp. 192-195
-
-
Falconer, I.R.1
Humpage, A.R.2
-
15
-
-
33746701372
-
Cyanobacterial (blue-green algal) toxins in water supplies: cylindrospermopsins
-
Falconer I.R., Humpage A.R. Cyanobacterial (blue-green algal) toxins in water supplies: cylindrospermopsins. Environ. Toxicol. 2006, 21:299-304.
-
(2006)
Environ. Toxicol.
, vol.21
, pp. 299-304
-
-
Falconer, I.R.1
Humpage, A.R.2
-
16
-
-
0141927335
-
Cell alterations but no DNA strand breaks induced in vitro by cylindrospermopsin in CHO K1 cells
-
Fessard V., Bernard C. Cell alterations but no DNA strand breaks induced in vitro by cylindrospermopsin in CHO K1 cells. Environ. Toxicol. 2003, 18(5):353-359.
-
(2003)
Environ. Toxicol.
, vol.18
, Issue.5
, pp. 353-359
-
-
Fessard, V.1
Bernard, C.2
-
17
-
-
0034767498
-
Cell-free protein synthesis inhibition assay for the cyanobacterial toxin cylindrospermopsin
-
Froscio S.M., Humpage A.R., Burcham P.C., Falconer I.R. Cell-free protein synthesis inhibition assay for the cyanobacterial toxin cylindrospermopsin. Environ. Toxicol. 2001, 16(5):408-412.
-
(2001)
Environ. Toxicol.
, vol.16
, Issue.5
, pp. 408-412
-
-
Froscio, S.M.1
Humpage, A.R.2
Burcham, P.C.3
Falconer, I.R.4
-
18
-
-
0042978772
-
Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes
-
Froscio S.M., Humpage A.R., Burcham P.C., Falconer I.R. Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes. Environ. Toxicol. 2003, 18(4):243-251.
-
(2003)
Environ. Toxicol.
, vol.18
, Issue.4
, pp. 243-251
-
-
Froscio, S.M.1
Humpage, A.R.2
Burcham, P.C.3
Falconer, I.R.4
-
19
-
-
67349129142
-
Comparative study of cyanotoxins affecting cytoskeletal and chromatin structures in CHO-K1 cells
-
Gácsi M., Antal O., Vasas G., Máthé C., Borbély G., Saker M.L., Gyo{double acute}ri J., Farkas A., Vehovszky A., Bánfalvi G. Comparative study of cyanotoxins affecting cytoskeletal and chromatin structures in CHO-K1 cells. Toxicol. In Vitro 2009, 23(4):710-718.
-
(2009)
Toxicol. In Vitro
, vol.23
, Issue.4
, pp. 710-718
-
-
Gácsi, M.1
Antal, O.2
Vasas, G.3
Máthé, C.4
Borbély, G.5
Saker, M.L.6
Gyori, J.7
Farkas, A.8
Vehovszky, A.9
Bánfalvi, G.10
-
20
-
-
0038508656
-
The Palm Island mystery disease 20 years on: a review of research on the cyanotoxin cylindrospermopsin
-
Griffiths D.J., Saker M.L. The Palm Island mystery disease 20 years on: a review of research on the cyanotoxin cylindrospermopsin. Environ. Toxicol. 2003, 18:78-93.
-
(2003)
Environ. Toxicol.
, vol.18
, pp. 78-93
-
-
Griffiths, D.J.1
Saker, M.L.2
-
21
-
-
33748068451
-
Carcinogenicity of nitrate, nitrite, and cyanobacterial peptide toxins
-
WHO International Agency for Research on Cancer Monograph Working Group
-
Grosse Y., Baan R., Straif K., Secretan B., El Ghissassi F., Cogliano V. Carcinogenicity of nitrate, nitrite, and cyanobacterial peptide toxins. Lancet Oncol. 2006, 7(8):628-629. WHO International Agency for Research on Cancer Monograph Working Group.
-
(2006)
Lancet Oncol.
, vol.7
, Issue.8
, pp. 628-629
-
-
Grosse, Y.1
Baan, R.2
Straif, K.3
Secretan, B.4
El Ghissassi, F.5
Cogliano, V.6
-
22
-
-
0022402504
-
Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir
-
Hawkins P.R., Runnegar M.T., Jackson A.R., Falconer I.R. Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir. Appl. Environ. Microbiol. 1985, 50:1292-1295.
-
(1985)
Appl. Environ. Microbiol.
, vol.50
, pp. 1292-1295
-
-
Hawkins, P.R.1
Runnegar, M.T.2
Jackson, A.R.3
Falconer, I.R.4
-
23
-
-
0025201229
-
Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases
-
Honkanen R.E., Zwiller J., Moore R.E., Daily S.L., Khatra B.S., Dukelow M., Boynton A.L. Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J. Biol. Chem. 1990, 265(32):19401-19404.
-
(1990)
J. Biol. Chem.
, vol.265
, Issue.32
, pp. 19401-19404
-
-
Honkanen, R.E.1
Zwiller, J.2
Moore, R.E.3
Daily, S.L.4
Khatra, B.S.5
Dukelow, M.6
Boynton, A.L.7
-
24
-
-
0034695122
-
Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin
-
Humpage A.R., Fenech M., Thomas P., Falconer I.R. Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mut. Res. 2000, 472(1-2):155-161.
-
(2000)
Mut. Res.
, vol.472
, Issue.1-2
, pp. 155-161
-
-
Humpage, A.R.1
Fenech, M.2
Thomas, P.3
Falconer, I.R.4
-
25
-
-
77951652282
-
-
Cylindrospermopsin genotoxicity and cytotoxicity: role of cytochrome P-450 and oxidative.
-
Humpage, A.R., Fontaine, F., Froscio, S., Burcham, P., Falconer, I.R., 2005. Cylindrospermopsin genotoxicity and cytotoxicity: role of cytochrome P-450 and oxidative.
-
(2005)
-
-
Humpage, A.R.1
Fontaine, F.2
Froscio, S.3
Burcham, P.4
Falconer, I.R.5
-
26
-
-
36048984373
-
No induction of structural chromosomal aberrations in cylindrospermopsin-treated CHO-K1 cells without and with metabolic activation
-
Lankoff A., Wojcik A., Lisowska H., Bialczyk J., Dziga D., Carmichael W.W. No induction of structural chromosomal aberrations in cylindrospermopsin-treated CHO-K1 cells without and with metabolic activation. Toxicon 2007, 50(8):1105-1115.
-
(2007)
Toxicon
, vol.50
, Issue.8
, pp. 1105-1115
-
-
Lankoff, A.1
Wojcik, A.2
Lisowska, H.3
Bialczyk, J.4
Dziga, D.5
Carmichael, W.W.6
-
27
-
-
0025333146
-
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants
-
MacKintosh C., Beattie K.A., Klumpp S., Cohen P., Codd G.A. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Lett. 1990, 264(2):187-192.
-
(1990)
FEBS Lett.
, vol.264
, Issue.2
, pp. 187-192
-
-
MacKintosh, C.1
Beattie, K.A.2
Klumpp, S.3
Cohen, P.4
Codd, G.A.5
-
29
-
-
23044502608
-
Di-(2-ethylhexyl)phthalate (DEHP) modifies Bcl-2/Bax ratio and changes c-myc expression in Syrian hamster embryo (SHE) cells
-
Maire M.A., Rast C., Vasseur P. Di-(2-ethylhexyl)phthalate (DEHP) modifies Bcl-2/Bax ratio and changes c-myc expression in Syrian hamster embryo (SHE) cells. Toxicol. Lett. 2005, 158:237-245.
-
(2005)
Toxicol. Lett.
, vol.158
, pp. 237-245
-
-
Maire, M.A.1
Rast, C.2
Vasseur, P.3
-
30
-
-
34250330392
-
2,4-dichlorophenoxyacetic acid: effects on Syrian hamster embryo (SHE) cell transformation, c-Myc expression, apoptosis and DNA damage
-
Maire M.A., Rast C., Landkocz Y., Vasseur P. 2,4-dichlorophenoxyacetic acid: effects on Syrian hamster embryo (SHE) cell transformation, c-Myc expression, apoptosis and DNA damage. Mut. Res. 2007, 631(2):124-136.
-
(2007)
Mut. Res.
, vol.631
, Issue.2
, pp. 124-136
-
-
Maire, M.A.1
Rast, C.2
Landkocz, Y.3
Vasseur, P.4
-
31
-
-
59849102430
-
Detailed review paper on cell transformation assays for detection of chemical carcinogens
-
ENV/JM/MONO 18, 2007-08-13, OECD, Paris, , OECD
-
OECD Detailed review paper on cell transformation assays for detection of chemical carcinogens. Series on Testing and Assessment 2007, No 31. ENV/JM/MONO 18, 2007-08-13, OECD, Paris, 164 pp. http://www.oecd.org/dataoecd/56/5/37863750.pdf.
-
(2007)
Series on Testing and Assessment
, vol.31
, pp. 164
-
-
-
32
-
-
0017395256
-
Morphological transformation of early passage golden Syrian hamster embryo cells derived from cryopreserved primary cultures as a reliable in vitro bioassay for identifying diverse carcinogens
-
Pienta R.J., Poiley J.A., Lebherz W.B. Morphological transformation of early passage golden Syrian hamster embryo cells derived from cryopreserved primary cultures as a reliable in vitro bioassay for identifying diverse carcinogens. Int. J. Cancer 1977, 19:642-655.
-
(1977)
Int. J. Cancer
, vol.19
, pp. 642-655
-
-
Pienta, R.J.1
Poiley, J.A.2
Lebherz, W.B.3
-
33
-
-
34247130037
-
The cyanobacterial toxin cylindrospermopsin, induces fetal toxicity in the mouse after exposure late in gestation
-
Rogers E.H., Zehr R.D., Gage M.I., Humpage A.R., Falconer I.R., Marr M., Chernoff N. The cyanobacterial toxin cylindrospermopsin, induces fetal toxicity in the mouse after exposure late in gestation. Toxicon 2007, 49(6):855-864.
-
(2007)
Toxicon
, vol.49
, Issue.6
, pp. 855-864
-
-
Rogers, E.H.1
Zehr, R.D.2
Gage, M.I.3
Humpage, A.R.4
Falconer, I.R.5
Marr, M.6
Chernoff, N.7
-
34
-
-
0028853288
-
Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
-
Runnegar M.T., Kong S.M., Zhong Y.Z., Lu S.C. Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes. Biochem. Pharmacol. 1995, 49:219-225.
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 219-225
-
-
Runnegar, M.T.1
Kong, S.M.2
Zhong, Y.Z.3
Lu, S.C.4
-
35
-
-
0028352665
-
The role of glutathione in the toxicity of a novel cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
-
Runnegar M.T., Kong S.M., Zhong Y.Z., Ge J.L., Lu S.C. The role of glutathione in the toxicity of a novel cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes. Biochem. Biophys. Res. Com. 1994, 201:235-241.
-
(1994)
Biochem. Biophys. Res. Com.
, vol.201
, pp. 235-241
-
-
Runnegar, M.T.1
Kong, S.M.2
Zhong, Y.Z.3
Ge, J.L.4
Lu, S.C.5
-
36
-
-
0036802862
-
Genotoxicity investigation of a cyanobacterial toxin, cylindrospermopsin
-
Shen X., Lam P.K., Shaw G.R., Wickramasinghe W. Genotoxicity investigation of a cyanobacterial toxin, cylindrospermopsin. Toxicon 2002, 40(10):1499-1501.
-
(2002)
Toxicon
, vol.40
, Issue.10
, pp. 1499-1501
-
-
Shen, X.1
Lam, P.K.2
Shaw, G.R.3
Wickramasinghe, W.4
-
37
-
-
0028200062
-
Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans
-
Terao K., Ohmori S., Igarashi K., Ohtani I., Watanabe M.F., Harada K.I., Ito E., Watanabe M. Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans. Toxicon 1994, 32(7):833-843.
-
(1994)
Toxicon
, vol.32
, Issue.7
, pp. 833-843
-
-
Terao, K.1
Ohmori, S.2
Igarashi, K.3
Ohtani, I.4
Watanabe, M.F.5
Harada, K.I.6
Ito, E.7
Watanabe, M.8
-
38
-
-
35448936434
-
Chemically induced carcinogenesis affecting chromatin structure in rat hepatocarcinoma cells
-
Trencsényi G., Kertai P., Somogyi C., Nagy G., Dombradi Z., Gacsi M., Banfalvi G. Chemically induced carcinogenesis affecting chromatin structure in rat hepatocarcinoma cells. DNA Cell Biol. 2007, 26(9):649-655.
-
(2007)
DNA Cell Biol.
, vol.26
, Issue.9
, pp. 649-655
-
-
Trencsényi, G.1
Kertai, P.2
Somogyi, C.3
Nagy, G.4
Dombradi, Z.5
Gacsi, M.6
Banfalvi, G.7
-
39
-
-
0022630578
-
An interlaboratory comparison of transformation in Syrian hamster embryo cells with model and coded chemicals
-
Tu A., Hallowell W., Pallotta S., Sivak A., Lubet R.A., Curren R.D., Avery M.D., Jones C., Sedita B.A., Huberman E., et al. An interlaboratory comparison of transformation in Syrian hamster embryo cells with model and coded chemicals. Environ. Mutagen. 1986, 8(1):77-98.
-
(1986)
Environ. Mutagen.
, vol.8
, Issue.1
, pp. 77-98
-
-
Tu, A.1
Hallowell, W.2
Pallotta, S.3
Sivak, A.4
Lubet, R.A.5
Curren, R.D.6
Avery, M.D.7
Jones, C.8
Sedita, B.A.9
Huberman, E.10
-
40
-
-
33846457375
-
Toxins of cyanobacteria
-
Van Apeldoorn M.E., Van Egmond H.P., Speijers G.J., Bakker G.J. Toxins of cyanobacteria. Mol. Nutr. Food Res. 2007, 51(1):7-60.
-
(2007)
Mol. Nutr. Food Res.
, vol.51
, Issue.1
, pp. 7-60
-
-
Van Apeldoorn, M.E.1
Van Egmond, H.P.2
Speijers, G.J.3
Bakker, G.J.4
-
41
-
-
0030103319
-
Promoting activity of microcystins extracted from waterblooms in SHE cell transformation assay
-
Wangth H.B., Zhuth H.G. Promoting activity of microcystins extracted from waterblooms in SHE cell transformation assay. Biomed. Environ. Sci. 1996, 9(1):46-51.
-
(1996)
Biomed. Environ. Sci.
, vol.9
, Issue.1
, pp. 46-51
-
-
Wangth, H.B.1
Zhuth, H.G.2
-
43
-
-
43849110966
-
Effects of blue-green algal toxin cylindrospermopsin (CYN) on human granulosa cells in vitro
-
Young F.M., Micklem J., Humpage A.R. Effects of blue-green algal toxin cylindrospermopsin (CYN) on human granulosa cells in vitro. Reprod. Toxicol. 2008, 25(3):374-380.
-
(2008)
Reprod. Toxicol.
, vol.25
, Issue.3
, pp. 374-380
-
-
Young, F.M.1
Micklem, J.2
Humpage, A.R.3
|