Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection

Environmental Toxicology

Volumn 27, Issue 5, 2012, Pages 277-284

  Bazin, Emmanuelle ^a   Huet, Sylvie ^a   Jarry, Gérard ^a   Hégarat, Ludovic Le ^a   Munday, John S ^b   Humpage, Andrew R ^c,d   Fessard, Valérie ^a  

^a Healthy Pigs Production and Experimentation Section   (France)

^b MASSEY UNIVERSITY   (New Zealand)

^c Cooperative Research Center for Water Quality and Treatment ^*  (Australia)

^d Australian Water Quality Center   (Australia)

Author keywords

Cylindrospermopsin; Genotoxicity; In vivo alkaline comet assay; In vivo micronucleus assay

Indexed keywords

AFTER-TREATMENT; ALKALINE COMET ASSAY; BONE MARROW; CHRONIC EFFECTS; COLON CELLS; CYLINDROSPERMOPSIN; CYTOTOXIC; DAMAGE EVENTS; DNA BREAKS; DNA DAMAGES; DOUBLE STRAND BREAKS; GENOTOXIC EFFECTS; GENOTOXICITIES; HEPATOTOXINS; HISTOLOGICAL EXAMINATION; IN-VIVO; INTRAPERITONEAL; INTRAPERITONEAL INJECTIONS; ORAL ADMINISTRATION;

AGRICULTURE; BONE; CELL DEATH; CHROMOSOMES; DNA; MAMMALS; METHANE; WATER SUPPLY;

DAMAGE DETECTION;

CYLINDROSPERMOPSIN; METHYL METHANE SULFONATE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

BIOASSAY; BLOOD; CHROMOSOME; CYANOBACTERIUM; ECOTOXICOLOGY; GENOTOXICITY; HISTOLOGY; MORTALITY; RODENT; TOXICITY TEST; TOXIN; WATER SUPPLY;

ALKALINE COMET ASSAY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BONE MARROW; CHROMOSOME BREAKAGE; COLON; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; ERYTHROCYTE; GENOTOXICITY; IN VIVO STUDY; INTESTINE; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; BACTERIAL TOXINS; BONE MARROW; COMET ASSAY; CYANOBACTERIA; DNA BREAKS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAPERITONEAL; KIDNEY; LIVER; MALE; MARINE TOXINS; METHYL METHANESULFONATE; MICE; MICROCYSTINS; MICRONUCLEUS TESTS; MUTAGENS; URACIL;

CYANOBACTERIA; CYLINDROSPERMOPSIS RACIBORSKII; MUS;

EID: 84859742065     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20640     Document Type: Article

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