Aliskiren, at low doses, reduces the electrical remodeling in the heart of the TGR(mRen2)27 rat independently of blood pressure

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 14, Issue 1, 2013, Pages 23-33

  De Mello, Walmor ^a   Rivera, Marielis ^b   Rabell, Andres ^a   Gerena, Yamil ^c  

^a UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

^b San Juan Bautista School of Medicine   (Puerto Rico)

^c School of Pharmacy   (United States)

Author keywords

cardiac electrophysiological remodeling; Direct renin inhibition; mechanical stretch; TGR(mRen2) 27 rat

Indexed keywords

ALISKIREN; ANGIOTENSIN II;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR PARAMETERS; CIRCADIAN RHYTHM; COMPETITIVE INHIBITION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROSING ALVEOLITIS; HEART EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE POSTERIOR WALL THICKNESS; HEART MUSCLE; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HYPERTENSION; LOW DRUG DOSE; MALE; MECHANICAL STRESS; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE;

ACTION POTENTIALS; AMIDES; ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGICAL PHENOMENA; FIBROSIS; FUMARATES; HEART; HEART VENTRICLES; MALE; MYOCARDIUM; RATS; RATS, TRANSGENIC; RECEPTOR, ANGIOTENSIN, TYPE 1; STRESS, MECHANICAL; SYSTOLE; VENTRICULAR REMODELING;

EID: 84874075137     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320312463832     Document Type: Article

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