Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: Pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate

Chemical Research in Toxicology

Volumn 26, Issue 2, 2013, Pages 213-220

  Harris, Stephanie R ^a   Zhang, Guo Fang ^a   Sadhukhan, Sushabhan ^b   Wang, Hua ^b   Shi, Chuan ^b   Puchowicz, Michelle A ^a   Anderson, Vernon E ^a   Salomon, Robert G ^b   Tochtrop, Gregory P ^b   Brunengraber, Henri ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,6 DIKETOHEPTANOYL COENZYME A; ACETYL COENZYME A; ACYL COENZYME A; ALCOHOL; CALCIUM LEVULINATE; CARBON; CYCLOPENTADIENYLACYL COENZYME A; CYCLOPENTENYL DERIVATIVE; CYCLOPENTENYLACYL COENZYME A; LEVULINIC ACID; LEVULINYL COENZYME A; LYSINE; METHYLPYRROLYLACETYL COENZYME A; NITROGEN; PYRROLYL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CATABOLISM; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYCLIZATION; DRUG ABUSE; FATTY ACID OXIDATION; LIVER; MALE; METABOLOMICS; NONHUMAN; RAT;

ANIMALS; BRAIN; COENZYME A; CYCLIZATION; ENZYME INHIBITORS; LEVULINIC ACIDS; LIVER; MALE; METABOLOMICS; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84874062913     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx3003643     Document Type: Article

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