메뉴 건너뛰기




Volumn 17, Issue , 1997, Pages 559-596

Applications of mass isotopomer analysis to nutrition research

Author keywords

Intermediary metabolism; Metabolic regulation; Nutrient metabolism; Stable isotopes; Tracer methodology

Indexed keywords

ISOTOPE;

EID: 0030746169     PISSN: 01999885     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.nutr.17.1.559     Document Type: Review
Times cited : (94)

References (136)
  • 1
    • 0029964729 scopus 로고    scopus 로고
    • Contributions of de novo synthesis of fatty acids and lipolysis to VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man
    • Aarsland A, Chinkes DL, Wolfe R. 1996. Contributions of de novo synthesis of fatty acids and lipolysis to VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man. J. Clin. Invest. 98:1-10
    • (1996) J. Clin. Invest. , vol.98 , pp. 1-10
    • Aarsland, A.1    Chinkes, D.L.2    Wolfe, R.3
  • 2
    • 0030938195 scopus 로고    scopus 로고
    • Hepatic and whole body fat synthesis in humans during carbohydrate overfeeding
    • Aarsland A, Wolfe RR, Chinkes D. 1997. Hepatic and whole body fat synthesis in humans during carbohydrate overfeeding. Am. J. Clin. Nutr. 65:1774-82
    • (1997) Am. J. Clin. Nutr. , vol.65 , pp. 1774-1782
    • Aarsland, A.1    Wolfe, R.R.2    Chinkes, D.3
  • 4
    • 0026784371 scopus 로고
    • Forearm ketone body metabolism in normal and in insulin-dependent diabetic patients
    • Avogaro A, Doria A, Gnudi L, Carrara A, Duner E, Brocco E, et al. 1992. Forearm ketone body metabolism in normal and in insulin-dependent diabetic patients. Am. J. Physiol. 263:E261-67
    • (1992) Am. J. Physiol. , vol.263
    • Avogaro, A.1    Doria, A.2    Gnudi, L.3    Carrara, A.4    Duner, E.5    Brocco, E.6
  • 5
    • 0025322353 scopus 로고
    • Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labeled with stable isotopes
    • Avogaro A, Nosadini R, Bier DM, Cobelli C, Toffolo G, et al. 1990. Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labeled with stable isotopes. Acta Diabetol. Lat. 27:41-51
    • (1990) Acta Diabetol. Lat. , vol.27 , pp. 41-51
    • Avogaro, A.1    Nosadini, R.2    Bier, D.M.3    Cobelli, C.4    Toffolo, G.5
  • 6
    • 0028839537 scopus 로고
    • Evidence for incorporation of intact dietary pyrimidine (but not purine) nucleosides into hepatic RNA
    • Berthold HK, Crain PF, Gouni I, Reeds PJ, Klein PD. 1995. Evidence for incorporation of intact dietary pyrimidine (but not purine) nucleosides into hepatic RNA. Proc. Natl. Acad. Sci. USA 92:10123-27
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10123-10127
    • Berthold, H.K.1    Crain, P.F.2    Gouni, I.3    Reeds, P.J.4    Klein, P.D.5
  • 8
    • 0028948918 scopus 로고
    • Isotopic evidence for the differential regulation of arginine and proline synthesis in man
    • Berthold HK, Reeds PJ, Klein PD. 1995. Isotopic evidence for the differential regulation of arginine and proline synthesis in man. Metabolism 44:466-73
    • (1995) Metabolism , vol.44 , pp. 466-473
    • Berthold, H.K.1    Reeds, P.J.2    Klein, P.D.3
  • 9
    • 0028473068 scopus 로고
    • The use of uniformly labeled substrates and mass isotopomer analysis to study intermediary metabolism
    • Berthold HK, Wykes LJ, Jahoor F, Klein PD, Reeds PJ. 1994. The use of uniformly labeled substrates and mass isotopomer analysis to study intermediary metabolism. Proc. Nutr. Soc. 53:345-54
    • (1994) Proc. Nutr. Soc. , vol.53 , pp. 345-354
    • Berthold, H.K.1    Wykes, L.J.2    Jahoor, F.3    Klein, P.D.4    Reeds, P.J.5
  • 11
    • 0026624926 scopus 로고
    • Leucine and phenylalanine kinetics during mixed meal ingestion: A multiple tracer approach
    • Biolo G, Tessari P, Inchiostro S, Bruttomesso D, Foncher C, et al. 1992. Leucine and phenylalanine kinetics during mixed meal ingestion: a multiple tracer approach. Am. J. Physiol. 262:E455-63
    • (1992) Am. J. Physiol. , vol.262
    • Biolo, G.1    Tessari, P.2    Inchiostro, S.3    Bruttomesso, D.4    Foncher, C.5
  • 12
    • 0029901757 scopus 로고    scopus 로고
    • Ribonucleic acid nucleotides in maternal and fetal tissues derive almost exclusively from synthesis de nova in pregnant mice
    • Boza JJ, Jahoor F, Reeds PJ. 1996. Ribonucleic acid nucleotides in maternal and fetal tissues derive almost exclusively from synthesis de nova in pregnant mice. J. Nutr. 126:1749-58
    • (1996) J. Nutr. , vol.126 , pp. 1749-1758
    • Boza, J.J.1    Jahoor, F.2    Reeds, P.J.3
  • 13
    • 0028982224 scopus 로고
    • 2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in the rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24 hydroxy-, and 25-hydrocholesterol
    • 2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in the rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24 hydroxy-, and 25-hydrocholesterol. J. Biol. Chem. 270:20278-84
    • (1995) J. Biol. Chem. , vol.270 , pp. 20278-20284
    • Breuer, O.1    Bjorkhelm, I.2
  • 15
    • 0017849474 scopus 로고
    • Fatty acid, 3-β-hydroxysterol, and ketone synthesis in the perfused rat liver. II. Effects of (-)-hydroxycitrate and oleate
    • Brunengraber H, Boutry M, Lowenstein JM. 1978. Fatty acid, 3-β-hydroxysterol, and ketone synthesis in the perfused rat liver. II. Effects of (-)-hydroxycitrate and oleate. Eur. J. Biochem. 82:373-84
    • (1978) Eur. J. Biochem. , vol.82 , pp. 373-384
    • Brunengraber, H.1    Boutry, M.2    Lowenstein, J.M.3
  • 17
    • 0029136533 scopus 로고
    • The role of nucleotides in human nutrition
    • Carver JD, Walker WA. 1995. The role of nucleotides in human nutrition. J. Nutr. Biochem. 6:58-72
    • (1995) J. Nutr. Biochem. , vol.6 , pp. 58-72
    • Carver, J.D.1    Walker, W.A.2
  • 20
    • 0029761104 scopus 로고    scopus 로고
    • A comparison of mass isotopomer dilution methods used to compute production of VLDL fatty acids in vivo in human subjects
    • Chinkes DL, Aarsland A, Rosenblatt J, Wolfe RR. 1996. A comparison of mass isotopomer dilution methods used to compute production of VLDL fatty acids in vivo in human subjects. Am. J. Physiol. 271:E373-83
    • (1996) Am. J. Physiol. , vol.271
    • Chinkes, D.L.1    Aarsland, A.2    Rosenblatt, J.3    Wolfe, R.R.4
  • 21
    • 0028845267 scopus 로고
    • Mass and positional isotopomer analysis of glucose metabolism in periportal and pericentral hepatocytes
    • Cline GW, Shulman GI. 1995. Mass and positional isotopomer analysis of glucose metabolism in periportal and pericentral hepatocytes. J. Biol. Chem. 270:28062-67
    • (1995) J. Biol. Chem. , vol.270 , pp. 28062-28067
    • Cline, G.W.1    Shulman, G.I.2
  • 22
    • 0023511517 scopus 로고
    • Models to interpret kinetic data in stable isotope tracer studies
    • Cobelli C, Toffolo G, Bier DM, Nosadini R. 1987. Models to interpret kinetic data in stable isotope tracer studies. Am. J. Physiol. 253:E551-64
    • (1987) Am. J. Physiol. , vol.253
    • Cobelli, C.1    Toffolo, G.2    Bier, D.M.3    Nosadini, R.4
  • 23
    • 0028350061 scopus 로고
    • Prediction of positional isotopomers of the citric acid cycle: The syntactic approach
    • Cohen DM, Bergman RN. 1994. Prediction of positional isotopomers of the citric acid cycle: the syntactic approach. Am. J. Physiol. 266:E341-50
    • (1994) Am. J. Physiol. , vol.266
    • Cohen, D.M.1    Bergman, R.N.2
  • 27
    • 0019359657 scopus 로고
    • The metabolic effects of dichloroacetate
    • Crabb DW, Yount EA, Harris RA. 1981. The metabolic effects of dichloroacetate. Metabolism 30:1024-39
    • (1981) Metabolism , vol.30 , pp. 1024-1039
    • Crabb, D.W.1    Yount, E.A.2    Harris, R.A.3
  • 28
    • 0028902940 scopus 로고
    • Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver: Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis
    • Des Rosiers C, Di Donato L, Comte B, Laplante A, Marcoux C, et al. 1995. Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver: Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis. J. Biol. Chem. 270:10027-36
    • (1995) J. Biol. Chem. , vol.270 , pp. 10027-10036
    • Des Rosiers, C.1    Di Donato, L.2    Comte, B.3    Laplante, A.4    Marcoux, C.5
  • 29
    • 0028006816 scopus 로고
    • Reversibility of the mitochondrial isocitrate dehydrogenase reaction in the perfused rat liver: Evidence from isotopomer analysis of citric acid cycle intermediates
    • Des Rosiers C, Fernandez CA, David F, Brunengraber H. 1994. Reversibility of the mitochondrial isocitrate dehydrogenase reaction in the perfused rat liver: Evidence from isotopomer analysis of citric acid cycle intermediates. J. Biol. Chem. 269:27179-82
    • (1994) J. Biol. Chem. , vol.269 , pp. 27179-27182
    • Des Rosiers, C.1    Fernandez, C.A.2    David, F.3    Brunengraber, H.4
  • 31
    • 0023688777 scopus 로고
    • Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry
    • Des Rosiers C, Montgomery JA, Desrochers S, Garneau M, David F, et al. 1988. Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry. Anal. Biochem. 173:96-105
    • (1988) Anal. Biochem. , vol.173 , pp. 96-105
    • Des Rosiers, C.1    Montgomery, J.A.2    Desrochers, S.3    Garneau, M.4    David, F.5
  • 34
    • 0029888309 scopus 로고    scopus 로고
    • In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water:determination of the average number of deuterium atoms incorporated
    • Diraison F, Pachiaudi C, Beylot M. 1996. In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water:determination of the average number of deuterium atoms incorporated. Metabolism 45:817-21
    • (1996) Metabolism , vol.45 , pp. 817-821
    • Diraison, F.1    Pachiaudi, C.2    Beylot, M.3
  • 35
    • 0031033070 scopus 로고    scopus 로고
    • Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: Use of simple gas chromatographic/mass spectrometric techniques
    • Diraison F, Pachiaudi C, Beylot M. 1997. Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: use of simple gas chromatographic/mass spectrometric techniques. J. Mass Spectrom. 32:81-86
    • (1997) J. Mass Spectrom. , vol.32 , pp. 81-86
    • Diraison, F.1    Pachiaudi, C.2    Beylot, M.3
  • 36
    • 0028814869 scopus 로고
    • Gluconeogenesis and glucuronidation in liver in vivo and the heterogeneity of hepatocyte function
    • Ekberg K, Chandramouli V, Kumaran K, Schumann WC, Wahren J, et al. 1995. Gluconeogenesis and glucuronidation in liver in vivo and the heterogeneity of hepatocyte function. J. Biol. Chem. 270:21715-17
    • (1995) J. Biol. Chem. , vol.270 , pp. 21715-21717
    • Ekberg, K.1    Chandramouli, V.2    Kumaran, K.3    Schumann, W.C.4    Wahren, J.5
  • 37
    • 0019975590 scopus 로고
    • Lipogenesis from ketone bodies in the isolated perfused rat liver; evidence for the cytosolic activation of acetoacetate
    • Endemann G, Goetz PG, Edmond J, Brunengraber H. 1982. Lipogenesis from ketone bodies in the isolated perfused rat liver; evidence for the cytosolic activation of acetoacetate. J. Biol. Chem. 257:3434-40
    • (1982) J. Biol. Chem. , vol.257 , pp. 3434-3440
    • Endemann, G.1    Goetz, P.G.2    Edmond, J.3    Brunengraber, H.4
  • 39
    • 0028901694 scopus 로고
    • 13C mass isotopomer distribution analysis of intermediates
    • 13C mass isotopomer distribution analysis of intermediates. J. Biol. Chem. 270:10037-42
    • (1995) J. Biol. Chem. , vol.270 , pp. 10037-10042
    • Fernandez, C.A.1    Des Rosiers, C.2
  • 41
    • 0021923458 scopus 로고
    • Kelone body production and disposal in diabetic ketosis. A comparison with fasting ketosis
    • Féry F, Balasse EO. 1985. Kelone body production and disposal in diabetic ketosis. A comparison with fasting ketosis. Diabetes 34:326-32
    • (1985) Diabetes , vol.34 , pp. 326-332
    • Féry, F.1    Balasse, E.O.2
  • 43
    • 0026164988 scopus 로고
    • Isoptopic determination of organic keto acid pentafluorobenzyl esters in biological fluids by negative chemical ionization gas chromatography/raass spectrometry
    • Hachey DL, Patterson BW, Reeds PJ, Elsas LJ. 1991. Isoptopic determination of organic keto acid pentafluorobenzyl esters in biological fluids by negative chemical ionization gas chromatography/raass spectrometry. Anal. Chem. 63:919-23
    • (1991) Anal. Chem. , vol.63 , pp. 919-923
    • Hachey, D.L.1    Patterson, B.W.2    Reeds, P.J.3    Elsas, L.J.4
  • 44
    • 0031570354 scopus 로고    scopus 로고
    • Tracing gluconeogenesis with deuterated water: Measurement of low deuterium enrichments on carbons 6 and 2 of glucose
    • Hazey JW, Powers L, Previs SF, Yang D, David F, et al. 1997. Tracing gluconeogenesis with deuterated water: measurement of low deuterium enrichments on carbons 6 and 2 of glucose. Anal. Biochem. 248:158-67
    • (1997) Anal. Biochem. , vol.248 , pp. 158-167
    • Hazey, J.W.1    Powers, L.2    Previs, S.F.3    Yang, D.4    David, F.5
  • 45
    • 0026425183 scopus 로고
    • Relationship between precursor enrichment and ratio of excess M2/excess M1 isotopomer frequencies in a secreted polymer
    • Hellerstein MK. 1991. Relationship between precursor enrichment and ratio of excess M2/excess M1 isotopomer frequencies in a secreted polymer. J. Biol. Chem. 266:10920-24
    • (1991) J. Biol. Chem. , vol.266 , pp. 10920-10924
    • Hellerstein, M.K.1
  • 47
    • 0022525686 scopus 로고
    • Glucuronides as noninvasive probes of intrahepatic metabolism: Pathways of glucose entry into compartmentalized hepatic UDP-glucose pools during glycogen accumulation
    • Hellerstein MK, Greenblatt DJ, Munro HN. 1986. Glucuronides as noninvasive probes of intrahepatic metabolism: pathways of glucose entry into compartmentalized hepatic UDP-glucose pools during glycogen accumulation. Proc. Natl. Acad. Sci. USA 83:7044-48
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7044-7048
    • Hellerstein, M.K.1    Greenblatt, D.J.2    Munro, H.N.3
  • 48
    • 0028926483 scopus 로고
    • Rate of glucose entry into hepatic undine diphosphoglucose by the direct pathway in fasted and fed states in normal humans
    • Hellerstein MK, Kaempfer S, Reid JS, Wu K, Shackelton CH. 1995. Rate of glucose entry into hepatic undine diphosphoglucose by the direct pathway in fasted and fed states in normal humans. Metabolism 44:172-82
    • (1995) Metabolism , vol.44 , pp. 172-182
    • Hellerstein, M.K.1    Kaempfer, S.2    Reid, J.S.3    Wu, K.4    Shackelton, C.H.5
  • 49
    • 0025988275 scopus 로고
    • Use of mass isotopomer distributions in secreted lipids to sample lipogenic acetyl-CoA pool in humans
    • Hellerstein MK, Kletke C, Kaempfer S, Wu K, Shackelton CH. 1991. Use of mass isotopomer distributions in secreted lipids to sample lipogenic acetyl-CoA pool in humans. Am. J. Physiol. 261:E479-86
    • (1991) Am. J. Physiol. , vol.261
    • Hellerstein, M.K.1    Kletke, C.2    Kaempfer, S.3    Wu, K.4    Shackelton, C.H.5
  • 50
    • 0026448766 scopus 로고
    • Mass isotopomer distribution analysis:a technique for measuring biosynthesis and turnover of polymers
    • Hellerstein MK, Neese RA. 1992. Mass isotopomer distribution analysis:a technique for measuring biosynthesis and turnover of polymers. Am. J. Physiol. 263:E988-1001
    • (1992) Am. J. Physiol. , vol.263
    • Hellerstein, M.K.1    Neese, R.A.2
  • 51
    • 0027377603 scopus 로고
    • Model for measuring absolute rates of hepatic de nova lipogenesis and reesterification of free fatty acids
    • Hellerstein MK, Neese RA, Schwarz JM. 1993. Model for measuring absolute rates of hepatic de nova lipogenesis and reesterification of free fatty acids. Am. J. Physiol. 265 :E814-20
    • (1993) Am. J. Physiol. , vol.265
    • Hellerstein, M.K.1    Neese, R.A.2    Schwarz, J.M.3
  • 53
    • 0025859708 scopus 로고
    • Sampling the lipogenic hepatic acetyl-CoA pool in vivo in the rat. Comparison of xenobiotic probe to values predicted from isotopomeric distribution in circulating lipids and measurement of lipogenesis and acetyl-CoA dilution
    • Hellerstein MK, Wu K, Kaempfer S, Kletke C, Shackelton CH. 1991. Sampling the lipogenic hepatic acetyl-CoA pool in vivo in the rat. Comparison of xenobiotic probe to values predicted from isotopomeric distribution in circulating lipids and measurement of lipogenesis and acetyl-CoA dilution. J. Biol. Chem. 266:10912-19
    • (1991) J. Biol. Chem. , vol.266 , pp. 10912-10919
    • Hellerstein, M.K.1    Wu, K.2    Kaempfer, S.3    Kletke, C.4    Shackelton, C.H.5
  • 54
    • 0016670964 scopus 로고
    • Metabolic consequences of diving in animals and man
    • Hochachka PW, Storey KB. 1975. Metabolic consequences of diving in animals and man. Science 187:613-21
    • (1975) Science , vol.187 , pp. 613-621
    • Hochachka, P.W.1    Storey, K.B.2
  • 55
    • 0025291071 scopus 로고
    • Evidence for diurnal periodicity in human cholesterol synthesis
    • Jones PJH, Schoeller DA. 1990. Evidence for diurnal periodicity in human cholesterol synthesis. J. Lipid Res. 31:667-73
    • (1990) J. Lipid Res. , vol.31 , pp. 667-673
    • Jones, P.J.H.1    Schoeller, D.A.2
  • 56
    • 0014340534 scopus 로고
    • Fatty acid synthesis in adipose tissue incubated in tritiated water
    • Jungas RL. 1965. Fatty acid synthesis in adipose tissue incubated in tritiated water. Biochemistry 7:3708-17
    • (1965) Biochemistry , vol.7 , pp. 3708-3717
    • Jungas, R.L.1
  • 57
    • 0027080622 scopus 로고
    • Hepatocyte heterogeneity in the metabolism of carboydrates
    • Jungerman K, Thurman RG. 1992. Hepatocyte heterogeneity in the metabolism of carboydrates. Enzyme 46:33-58
    • (1992) Enzyme , vol.46 , pp. 33-58
    • Jungerman, K.1    Thurman, R.G.2
  • 58
    • 0022462194 scopus 로고
    • Metabolic pathways leading to liver glycogen repletion in vivo, studied by GCMS and NMR
    • Kalderon B, Gopher A, Lapidot A. 1986. Metabolic pathways leading to liver glycogen repletion in vivo, studied by GCMS and NMR. FEBS Lett. 204:29-32
    • (1986) FEBS Lett. , vol.204 , pp. 29-32
    • Kalderon, B.1    Gopher, A.2    Lapidot, A.3
  • 59
    • 0024451950 scopus 로고
    • Glucose recycling and production in glycogenosis type I and III:stable isotope technique study
    • Kalderon B, Korman SH, Gutman A, Lapidot A. 1989. Glucose recycling and production in glycogenosis type I and III:stable isotope technique study. Am. J. Physiol. 257:E346-53
    • (1989) Am. J. Physiol. , vol.257
    • Kalderon, B.1    Korman, S.H.2    Gutman, A.3    Lapidot, A.4
  • 61
    • 0030034667 scopus 로고    scopus 로고
    • Stable isotope tracers for studies of glucose metabolism
    • Kalhan SC. 1996. Stable isotope tracers for studies of glucose metabolism. J. Nutr. 126:S362-69
    • (1996) J. Nutr. , vol.126
    • Kalhan, S.C.1
  • 62
    • 0024478366 scopus 로고
    • 13C]glucose turnover into various metabolic pools for the differential diagnosis of lactic acidemias
    • 13C]glucose turnover into various metabolic pools for the differential diagnosis of lactic acidemias. Anal. Biochem. 176:382-89
    • (1989) Anal. Biochem. , vol.176 , pp. 382-389
    • Kassel, D.B.1    Glerum, M.2    Robinson, B.H.3    Sweely, C.C.4
  • 63
    • 0026058960 scopus 로고
    • Application of mass isotopomer analysis for determination of pathways of glycogen synthesis
    • Katz J, Lee WNP. 1991. Application of mass isotopomer analysis for determination of pathways of glycogen synthesis. Am. J. Physiol. 261:E332-36
    • (1991) Am. J. Physiol. , vol.261
    • Katz, J.1    Lee, W.N.P.2
  • 67
    • 5644232699 scopus 로고
    • Isotopomer spectral analysis: Encountering variable pool size and enrichment
    • Abstr.
    • Kelleher JK. 1995. Isotopomer spectral analysis: Encountering variable pool size and enrichment. Ann. Biomed. Eng. 23:S72 (Abstr.)
    • (1995) Ann. Biomed. Eng. , vol.23
    • Kelleher, J.K.1
  • 69
    • 0026522051 scopus 로고
    • Model equations for condensation biosynthesis using stable isotopes and radioisotopes
    • Kelleher JK, Masterson TM. 1992. Model equations for condensation biosynthesis using stable isotopes and radioisotopes. Am. J. Physiol. 262:E118-25
    • (1992) Am. J. Physiol. , vol.262
    • Kelleher, J.K.1    Masterson, T.M.2
  • 70
    • 0031032537 scopus 로고    scopus 로고
    • Glucose production and gluconeogenesis are negatively related to body weight in mechanically-ventilated very-low-birth-weight neonates
    • Keshen T, Miller R, Jahoor F, Jaksic T, Reeds PJ. 1997. Glucose production and gluconeogenesis are negatively related to body weight in mechanically-ventilated very-low-birth-weight neonates. Pediatr. Res. 41:132-38
    • (1997) Pediatr. Res. , vol.41 , pp. 132-138
    • Keshen, T.1    Miller, R.2    Jahoor, F.3    Jaksic, T.4    Reeds, P.J.5
  • 72
    • 0027487855 scopus 로고
    • Estimating gluconeogenic rates in NIDDM
    • Landau BR. 1993. Estimating gluconeogenic rates in NIDDM. Adv. Exp. Med. Biol. 334:209-20
    • (1993) Adv. Exp. Med. Biol. , vol.334 , pp. 209-220
    • Landau, B.R.1
  • 73
    • 0022615814 scopus 로고
    • A potential pitfall in the use of isotopes to measure ketone body production
    • Landau BR. 1986. A potential pitfall in the use of isotopes to measure ketone body production. Metabolism 35:94-95
    • (1986) Metabolism , vol.35 , pp. 94-95
    • Landau, B.R.1
  • 74
    • 0028831071 scopus 로고
    • A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans: Hepatic heterogeneity in glycerol metabolism
    • Landau BR, Fernandez CA, Previs SF, Ekberg K, Chandramouli V, et al. 1995. A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans: Hepatic heterogeneity in glycerol metabolism. Am. J. Physiol. 269:E18-E26
    • (1995) Am. J. Physiol. , vol.269
    • Landau, B.R.1    Fernandez, C.A.2    Previs, S.F.3    Ekberg, K.4    Chandramouli, V.5
  • 80
    • 0029949566 scopus 로고    scopus 로고
    • Stable isotopes and mass isotopomer study of fatty acid and cholesterol synthesis: A review of the MIDA approach
    • ed. D Heber, D Kritchevsky, New York: Plenum
    • Lee WNP. 1996. Stable isotopes and mass isotopomer study of fatty acid and cholesterol synthesis: a review of the MIDA approach. In Dietary Fats, Lipids, Hormones and Tumorogenesis, ed. D Heber, D Kritchevsky, pp. 95-114. New York: Plenum
    • (1996) Dietary Fats, Lipids, Hormones and Tumorogenesis , pp. 95-114
    • Lee, W.N.P.1
  • 81
    • 0027493834 scopus 로고
    • Appendix. Analysis of tricarboxylic acid cycle using mass isotopomer ratios
    • Lee WNP. 1993. Appendix. Analysis of tricarboxylic acid cycle using mass isotopomer ratios. J. Biol. Chem. 268:25522-26
    • (1993) J. Biol. Chem. , vol.268 , pp. 25522-25526
    • Lee, W.N.P.1
  • 84
    • 0026816626 scopus 로고
    • Mass isotopomer pattern and precursor-product relationship
    • Lee WNP, Bergner EA, Guo ZK. 1992. Mass isotopomer pattern and precursor-product relationship. Biol. Mass Spectrom. 21:114-22
    • (1992) Biol. Mass Spectrom. , vol.21 , pp. 114-122
    • Lee, W.N.P.1    Bergner, E.A.2    Guo, Z.K.3
  • 85
    • 0028961757 scopus 로고
    • Isotopomer study of lipogenesis in human hepatoma cells in culture: Contribution of carbon and hydrogen atoms from glucose
    • Lee WNP, Byerly LO, Bassilian S, Ajie HO, Clark I, et al. 1995. Isotopomer study of lipogenesis in human hepatoma cells in culture: contribution of carbon and hydrogen atoms from glucose. Anal. Biochem. 226:100-12
    • (1995) Anal. Biochem. , vol.226 , pp. 100-112
    • Lee, W.N.P.1    Byerly, L.O.2    Bassilian, S.3    Ajie, H.O.4    Clark, I.5
  • 88
    • 0000817091 scopus 로고
    • Appendix. Analysis of mass isotopomer data
    • Lee WNP. 1989. Appendix. Analysis of mass isotopomer data. J. Biol. Chem. 264:13002-4
    • (1989) J. Biol. Chem. , vol.264 , pp. 13002-13004
    • Lee, W.N.P.1
  • 89
    • 0027448162 scopus 로고
    • Measurement of human lipogenesis using deuterium incorporation
    • Leitch CA, Jones PJH. 1993. Measurement of human lipogenesis using deuterium incorporation. J. Lipid Res. 34:157-63
    • (1993) J. Lipid Res. , vol.34 , pp. 157-163
    • Leitch, C.A.1    Jones, P.J.H.2
  • 91
    • 0027174772 scopus 로고
    • Glucose metabolism in mammalian cells as determined by mass isotopomer analysis
    • Lin YY, Cheng WB, Wright CE. 1993. Glucose metabolism in mammalian cells as determined by mass isotopomer analysis. Anal. Biochem. 209:267-73
    • (1993) Anal. Biochem. , vol.209 , pp. 267-273
    • Lin, Y.Y.1    Cheng, W.B.2    Wright, C.E.3
  • 92
    • 0015217043 scopus 로고
    • Effect of (-)-hydroxycitrate on fatty acid synthesis by rat liver in vivo
    • Lowenstein JM. 1971. Effect of (-)-hydroxycitrate on fatty acid synthesis by rat liver in vivo. J. Biol. Chem. 246:629-32
    • (1971) J. Biol. Chem. , vol.246 , pp. 629-632
    • Lowenstein, J.M.1
  • 93
    • 0016410112 scopus 로고
    • Measurement of rates of lipogenesis with deuterated and tritiated water
    • Lowenstein JM, Brunengraber H, Wadke M. 1975. Measurement of rates of lipogenesis with deuterated and tritiated water. Methods Enzymol. 35:279
    • (1975) Methods Enzymol. , vol.35 , pp. 279
    • Lowenstein, J.M.1    Brunengraber, H.2    Wadke, M.3
  • 94
    • 0023484513 scopus 로고
    • Quantitation of the pathways of hepatic glycogen formation in ingesting a glucose load
    • Magnusson I, Chandramouli V, Schumann WC, Kumaran K, Wahren J, et al. 1987. Quantitation of the pathways of hepatic glycogen formation in ingesting a glucose load. J. Clin. Invest. 80:1748-54
    • (1987) J. Clin. Invest. , vol.80 , pp. 1748-1754
    • Magnusson, I.1    Chandramouli, V.2    Schumann, W.C.3    Kumaran, K.4    Wahren, J.5
  • 98
    • 0023847678 scopus 로고
    • Measurement of urinary lactic, 3-hydroxybutyric, pyruvic and acetoacetic acids in a single analysis using selcted ion monitoring and stable isotope labeling techniques
    • Mamer OA. 1988. Measurement of urinary lactic, 3-hydroxybutyric, pyruvic and acetoacetic acids in a single analysis using selcted ion monitoring and stable isotope labeling techniques. Biomed. Environ. Mass Spectrom. 15:57-62
    • (1988) Biomed. Environ. Mass Spectrom. , vol.15 , pp. 57-62
    • Mamer, O.A.1
  • 100
    • 0027988512 scopus 로고
    • Non-steady state model applicable to NMR studies for calculating flux rates in glycolysis, gluconeogenesis, and citric acid cycle
    • Martin G, Chauvin MF, Dugelay S, Baverel G. 1994. Non-steady state model applicable to NMR studies for calculating flux rates in glycolysis, gluconeogenesis, and citric acid cycle. J. Biol. Chem. 269:26034-39
    • (1994) J. Biol. Chem. , vol.269 , pp. 26034-26039
    • Martin, G.1    Chauvin, M.F.2    Dugelay, S.3    Baverel, G.4
  • 101
    • 0028592648 scopus 로고
    • Metabolic interactions between surplus dietary energy intake and cigarette smoking or its cessation
    • Neese RA, Benowitz NL, Hoh R, Faix D, LaBua A, et al. 1994. Metabolic interactions between surplus dietary energy intake and cigarette smoking or its cessation. Am. J. Physiol. 267:E1023-34
    • (1994) Am. J. Physiol. , vol.267
    • Neese, R.A.1    Benowitz, N.L.2    Hoh, R.3    Faix, D.4    LaBua, A.5
  • 102
    • 0027530502 scopus 로고
    • Measurement of endogenous synthesis of serum cholesterol in vivo rats and humans using mass isotopomer distribution analysis (MIDA)
    • Neese RA, Faix D, Kletke C, Wu K, Shackleton CHL, et al. 1993. Measurement of endogenous synthesis of serum cholesterol in vivo rats and humans using mass isotopomer distribution analysis (MIDA). Am. J. Physiol. 264:E136-47
    • (1993) Am. J. Physiol. , vol.264
    • Neese, R.A.1    Faix, D.2    Kletke, C.3    Wu, K.4    Shackleton, C.H.L.5
  • 103
    • 0029031755 scopus 로고
    • Appendix. Calculations for gluconeogenesis by MIDA
    • Neese RA, Hellerstein MK. 1995. Appendix. Calculations for gluconeogenesis by MIDA. J. Biol. Chem. 270:14464-66
    • (1995) J. Biol. Chem. , vol.270 , pp. 14464-14466
    • Neese, R.A.1    Hellerstein, M.K.2
  • 104
    • 0028980981 scopus 로고
    • Gluconeogenesis and intrahepatic triose phosphate flux in response to fasting or substrate loads
    • Neese RA, Schwartz JM, Faix D, Turner SM, Vu D, et al. 1995. Gluconeogenesis and intrahepatic triose phosphate flux in response to fasting or substrate loads. J. Biol. Chem. 270:14452-63
    • (1995) J. Biol. Chem. , vol.270 , pp. 14452-14463
    • Neese, R.A.1    Schwartz, J.M.2    Faix, D.3    Turner, S.M.4    Vu, D.5
  • 105
    • 0029664916 scopus 로고    scopus 로고
    • 3 enrichment in biological samples by gas chromatography/electron impact ionization mass spectrometry
    • 3 enrichment in biological samples by gas chromatography/electron impact ionization mass spectrometry. J. Mass. Spectrom. 31:289-94
    • (1996) J. Mass. Spectrom. , vol.31 , pp. 289-294
    • Nieto, R.1    Calder, A.G.2    Anderson, S.E.3    Lobley, G.E.4
  • 108
    • 0029360338 scopus 로고
    • 13C]glycerol and mass isotopomer distribution analysis of glucose
    • 13C]glycerol and mass isotopomer distribution analysis of glucose. Am. J. Physiol. 269:E516-23
    • (1995) Am. J. Physiol. , vol.269
    • Péroni, O.1    Large, V.2    Beylot, M.3
  • 110
    • 8544272954 scopus 로고    scopus 로고
    • Labeling heterogeneity of glucose in hepatocytes incubated with glycerol, lactate and pyruvate: Evaluation of limitations and hepatic zonation of glycerokinase activity
    • Abstr. 2525
    • Previs SF, Hallowell PT, David F, Neimanis K, Brunengraber H. 1997. Labeling heterogeneity of glucose in hepatocytes incubated with glycerol, lactate and pyruvate: Evaluation of limitations and hepatic zonation of glycerokinase activity. FASEB J. 11:A436 (Abstr. 2525)
    • (1997) FASEB J. , vol.11
    • Previs, S.F.1    Hallowell, P.T.2    David, F.3    Neimanis, K.4    Brunengraber, H.5
  • 111
    • 0029090128 scopus 로고
    • Limitations of mass isotopomer distribution analysis of glucose to study gluconeogenesis: Substrate cycling between glycerol and triose phosphates in liver
    • Previs SF, Fernandez CA, Yang D, Soloviev MV, David F, Brunengraber H. 1995. Limitations of mass isotopomer distribution analysis of glucose to study gluconeogenesis: Substrate cycling between glycerol and triose phosphates in liver. J. Biol. Chem. 270:19806-15
    • (1995) J. Biol. Chem. , vol.270 , pp. 19806-19815
    • Previs, S.F.1    Fernandez, C.A.2    Yang, D.3    Soloviev, M.V.4    David, F.5    Brunengraber, H.6
  • 113
    • 8544249590 scopus 로고    scopus 로고
    • Assay of the concentration and stable isotopic enrichment of formaldehyde by GC-MS of hexamethylenetetramine (HMT)
    • Abstr. 2227
    • Reszko AE, Yang D, Brunengraber H. 1997. Assay of the concentration and stable isotopic enrichment of formaldehyde by GC-MS of hexamethylenetetramine (HMT). FASEB J. 11:A385 (Abstr. 2227)
    • (1997) FASEB J. , vol.11
    • Reszko, A.E.1    Yang, D.2    Brunengraber, H.3
  • 114
    • 0001607995 scopus 로고
    • Acyl-CoA dehydrogenase deficiencies
    • ed. CR Scriver, New York: McGraw-Hill
    • Roe CR, Coates PM. 1989. Acyl-CoA dehydrogenase deficiencies. In The Metabolic Basis of Inherited Disease I, ed. CR Scriver, pp. 889-931. New York: McGraw-Hill
    • (1989) The Metabolic Basis of Inherited Disease , vol.1 , pp. 889-931
    • Roe, C.R.1    Coates, P.M.2
  • 115
    • 0026699650 scopus 로고
    • Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects
    • Rosenblatt J, Chinkes D, Wolfe M, Wolfe RR. 1992. Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects. Am. J. Physiol. 263:E584-96
    • (1992) Am. J. Physiol. , vol.263
    • Rosenblatt, J.1    Chinkes, D.2    Wolfe, M.3    Wolfe, R.R.4
  • 116
    • 0028849608 scopus 로고
    • Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting
    • Rother KI, Schwenk WF. 1995. Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting. Am. J. Physiol. 269:E766-73
    • (1995) Am. J. Physiol. , vol.269
    • Rother, K.I.1    Schwenk, W.F.2
  • 117
    • 0028339522 scopus 로고
    • Proton-translocating transhydrogenase and NAD- and NADP-linked isocitrate dehydrogenase operate in a substrate cycle which contributes to fine regulation of tricarboxylic acid cycle activity in mitochondria
    • Sazanov LA, Jackson JB. 1994. Proton-translocating transhydrogenase and NAD- and NADP-linked isocitrate dehydrogenase operate in a substrate cycle which contributes to fine regulation of tricarboxylic acid cycle activity in mitochondria. FEBS Lett. 344:109-16
    • (1994) FEBS Lett. , vol.344 , pp. 109-116
    • Sazanov, L.A.1    Jackson, J.B.2
  • 118
    • 0013162158 scopus 로고
    • Deuterium as an indicator in the study of intermediary metabolism
    • Schoenheimer R, Rittenberg DJ. 1937. Deuterium as an indicator in the study of intermediary metabolism. J. Biol. Chem. 114:381-96
    • (1937) J. Biol. Chem. , vol.114 , pp. 381-396
    • Schoenheimer, R.1    Rittenberg, D.J.2
  • 121
    • 0021986886 scopus 로고
    • A novel approach to the analysis of the mass spectrally assayed stable isotope-labeling experiments
    • Strong JM, Upton DK, Anderson LW, Monks A, Chisena CA, et al. 1988. A novel approach to the analysis of the mass spectrally assayed stable isotope-labeling experiments. J. Biol. Chem. 260:4276-81
    • (1988) J. Biol. Chem. , vol.260 , pp. 4276-4281
    • Strong, J.M.1    Upton, D.K.2    Anderson, L.W.3    Monks, A.4    Chisena, C.A.5
  • 123
    • 0025828305 scopus 로고
    • Metabolic conversion of dicarboxylic acids to succinate in rat liver homogenates. A stable isotope tracer study
    • Tserng KY, Jin SJ. 1991. Metabolic conversion of dicarboxylic acids to succinate in rat liver homogenates. A stable isotope tracer study. J. Biol. Chem. 266:2924-29
    • (1991) J. Biol. Chem. , vol.266 , pp. 2924-2929
    • Tserng, K.Y.1    Jin, S.J.2
  • 124
    • 0027686728 scopus 로고
    • Determination of the isotope enrichment of one or a mixture of two stable labeled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies
    • Vogt JA, Chapman TE, Wagner DA, Young VR, Burke JF. 1993. Determination of the isotope enrichment of one or a mixture of two stable labeled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies. Biol. Mass. Spectrom. 22:600-12
    • (1993) Biol. Mass. Spectrom. , vol.22 , pp. 600-612
    • Vogt, J.A.1    Chapman, T.E.2    Wagner, D.A.3    Young, V.R.4    Burke, J.F.5
  • 126
    • 0017782874 scopus 로고
    • Studies on fatty acid omega-oxidation. Antiketogenic effect and gluconeogenicity of dicarboxylic acids
    • Wada F, Usami M. 1977. Studies on fatty acid omega-oxidation. Antiketogenic effect and gluconeogenicity of dicarboxylic acids. Biochim. Biophys. Acta 487:361-68
    • (1977) Biochim. Biophys. Acta , vol.487 , pp. 361-368
    • Wada, F.1    Usami, M.2
  • 130
    • 8544222365 scopus 로고    scopus 로고
    • Deleted in proof
    • Deleted in proof.
  • 131
    • 8544280458 scopus 로고
    • Serine and alanine derive from different three-carbon presursor pools: Evidence from mass isotopomer-analysis
    • Abstr. #2676
    • Wykes LJ, Jahoor F, Reeds PJ, Fraser ME, DelRasio M. 1994. Serine and alanine derive from different three-carbon presursor pools: Evidence from mass isotopomer-analysis. FASEB J. 8:A462 (Abstr. #2676)
    • (1994) FASEB J. , vol.8
    • Wykes, L.J.1    Jahoor, F.2    Reeds, P.J.3    Fraser, M.E.4    DelRasio, M.5
  • 132
    • 33750146534 scopus 로고    scopus 로고
    • GC-MS assay of low concentration and stable isotopic enrichment of plasma ammonia
    • Abstr. 1552
    • Yang D, Hazey JH, Powers L, David F, Singh J, et al. 1997. GC-MS assay of low concentration and stable isotopic enrichment of plasma ammonia. FASEB J. II:A267(Abstr. 1552)
    • (1997) FASEB J. , vol.2
    • Yang, D.1    Hazey, J.H.2    Powers, L.3    David, F.4    Singh, J.5
  • 133
    • 15844413142 scopus 로고    scopus 로고
    • Non-invasive probing of liver citric acid cycle intermediates with phenylacetyl-glutamine
    • Yang D, Previs SF, Fernandez CA, Dugelay S, Soloviev MV, et al. 1996. Non-invasive probing of liver citric acid cycle intermediates with phenylacetyl-glutamine. Am. J. Physiol. 270:E882-89
    • (1996) Am. J. Physiol. , vol.270
    • Yang, D.1    Previs, S.F.2    Fernandez, C.A.3    Dugelay, S.4    Soloviev, M.V.5
  • 135
    • 0028346376 scopus 로고
    • Non-homogeneous labeling of liver extra-mitochondrial acetyl-CoA: Implications for the probing of lipogenic acetyl-CoA via drug acetylation and for the production of acetate by the liver
    • Zhang Y, Agarwal KC, Beylot M, Soloviev MV, David F, et al. 1994. Non-homogeneous labeling of liver extra-mitochondrial acetyl-CoA: Implications for the probing of lipogenic acetyl-CoA via drug acetylation and for the production of acetate by the liver. J. Biol. Chem. 269:11025-29
    • (1994) J. Biol. Chem. , vol.269 , pp. 11025-11029
    • Zhang, Y.1    Agarwal, K.C.2    Beylot, M.3    Soloviev, M.V.4    David, F.5
  • 136
    • 0027244362 scopus 로고
    • Assay of the acetyl-CoA probe acetyl-sulfamethoxazole and of sulfamethoxazole by gas chromatography-mass spectrometry
    • Zhang Y, Agarwal KC, Beylot, M, Soloviev MV, David F, et al. 1993. Assay of the acetyl-CoA probe acetyl-sulfamethoxazole and of sulfamethoxazole by gas chromatography-mass spectrometry. Anal. Biochem. 212:481-86
    • (1993) Anal. Biochem. , vol.212 , pp. 481-486
    • Zhang, Y.1    Agarwal, K.C.2    Beylot, M.3    Soloviev, M.V.4    David, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.