Benomyl and colchicine synergistically inhibit cell proliferation and mitosis: Evidence of distinct binding sites for these agents in tubulin

Biochemistry

Volumn 47, Issue 49, 2008, Pages 13016-13025

  Clément, Marie Jeanne ^a   Rathinasamy, Krishnan ^b   Adjadj, Elisabeth ^a   Toma, Flavio ^a   Curmi, Patrick A ^a   Panda, Dulal ^b  

^a UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^b INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENTS; CELL CULTURE; CELL PROLIFERATION; FUNGICIDES; LANTHANUM COMPOUNDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BENZIMIDAZOLE GROUPS; CELL-CYCLE PROGRESSION; COLCHICINE BINDING; COMPETITIVE BINDING; FLUORESCENCE STUDIES; SATURATION TRANSFER DIFFERENCE NMR; SYNERGISTIC ACTIVITY; SYNERGISTIC EFFECT;

BINDING SITES;

ANTIFUNGAL AGENT; ANTIMITOTIC AGENT; BENOMYL; BENZIMIDAZOLE; COLCHICINE; TUBULIN;

ARTICLE; BRAIN; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG POTENTIATION; DRUG PROTEIN BINDING; GOAT; HELA CELL; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; SHEEP; YEAST;

CAPRA HIRCUS;

EID: 57449091909     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801136q     Document Type: Article

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