Osprey: Protein design with ensembles, flexibility, and provable algorithms

Methods in Enzymology

Volumn 523, Issue , 2013, Pages 87-107

  Gainza, Pablo ^a   Roberts, Kyle E ^a   Georgiev, Ivelin ^a,e   Lilien, Ryan H ^b   Keedy, Daniel A ^c   Chen, Cheng Yu ^c   Reza, Faisal ^c,f   Anderson, Amy C ^d   Richardson, David C ^c   Richardson, Jane S ^c   Donald, Bruce R ^a,c  

^a Duke University   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF CONNECTICUT   (United States)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dead end elimination; K; minDEE; osprey; Protein design; Protein ensembles; Protein flexibility

Indexed keywords

DIHYDROFOLIC ACID; PROTEIN; TRANSCRIPTION FACTOR RUNX1;

ADENYLATION; ALGORITHM; AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BINDING AFFINITY; CHLORIDE TRANSPORT; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG RESISTANCE; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; MOLECULAR MODEL; MUTATION; NUCLEAR MAGNETIC RESONANCE; PARTITION COEFFICIENT; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 84874028898     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394292-0.00005-9     Document Type: Chapter

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