Preparation and evaluation of solid dispersion for nitrendipine-carbopol and nitrendipine-HPMCP systems using a twin screw extruder

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 10, 2005, Pages 1240-1245

  Wang, Liang ^a   De Cui, Fu ^a   Hayase, Tomokazu ^b   Sunada, Hisakazu ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Carbopol; Hydroxypropylmethylcellulosephthalate (HPMCP); Nitrendipine; Solid dispersion; Twin screw extruder

Indexed keywords

ACRYLIC ACID; CARBOMER; DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; NITRENDIPINE;

ARTICLE; CROSS LINKING; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STRUCTURE; EVALUATION; HYDROGEN BOND; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; SOLID; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG CARRIERS; HYDROGEN BONDING; METHYLCELLULOSE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NITRENDIPINE; POLYVINYLS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 26444493103     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.53.1240     Document Type: Article

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