Synthesis, characterization, anticancer, and antioxidant activity of some new thiazolidin-4-ones in MCF-7 cells

Medicinal Chemistry Research

Volumn 22, Issue 2, 2013, Pages 758-767

  Isloor, Arun M ^a   Sunil, Dhanya ^b   Shetty, Prakash ^b   Malladi, Shridhar ^a   Pai, K S R ^c   Maliyakkl, Naseer ^c  

^a NATIONAL INSTITUTE OF TECHNOLOGY KARNATAKA   (India)

^b MANIPAL INSTITUTE OF TECHNOLOGY   (India)

^c MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Antioxidant activity; Cytotoxicity; DNA fragmentation; Thiazolidin 4 one

Indexed keywords

2 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 (2 TOLYLOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 (4 TOLYLOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 (PHENOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 [(NAPHTHALEN 1 YLOXY)METHYL] 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 [(NAPHTHALEN 2 YLOXY)] 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 FLUOROPHENYL) 1H PYRAZOL 4 YL] 3 (3 MERCAPTO 5 (2 TOLYLOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 FLUOROPHENYL) 1H PYRAZOL 4 YL] 3 (3 MERCAPTO 5 (4 TOLYLOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 FLUOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 (PHENOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 FLUOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 [(NAPHTHALEN 1YLOXY)]METHYL] 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 2 [3 (4 FLUOROPHENYL) 1H PYRAZOL 4 YL] 3 [3 MERCAPTO 5 [(NAPHTHALEN 2 YLOXY)METHYL] 4H 1,2,4 TRIAZOL 4 YL]THIAZOLIDIN 4 ONE; 3 [3 MERCAPTO 5 (2 TOLYLOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL] 2 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL]THIAZOLIDIN 4 ONE; 3 [3 MERCAPTO 5 (4 TOLYLOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL] 2 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL]THIAZOLIDIN 4 ONE; 3 [3 MERCAPTO 5 (PHENOXYMETHYL) 4H 1,2,4 TRIAZOL 4 YL] 2 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL]THIAZOLIDIN 4 ONE; 3 [3 MERCAPTO 5 [(NAPHTHALEN 1 YLOXY)METHYL] 4H 1,2,4 TRIAZOL 4 YL] 2 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL]THIAZOLIDIN 4 ONE; 3 [3 MERCAPTO 5 [(NAPHTHALEN 2 YLOXY)METHYL] 4H 1,2,4 TRIAZOL 4 YL] 2 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL]THIAZOLIDIN 4 ONE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ASCORBIC ACID; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG BIOAVAILABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; INFRARED SPECTROSCOPY; LIPOPHILICITY; MASS SPECTROMETRY; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84873991174     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0071-5     Document Type: Article

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