Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives

European Journal of Medicinal Chemistry

Volumn 46, Issue 8, 2011, Pages 3531-3536

  Vijesh, A M ^a,b   Isloor, Arun M ^b   Telkar, Sandeep ^c   Peethambar, S K ^c   Rai, Sankappa ^d   Isloor, Nishitha ^b  

^a SeQuent Scientific Ltd   (India)

^b NATIONAL INSTITUTE OF TECHNOLOGY KARNATAKA   (India)

^c KUVEMPU UNIVERSITY   (India)

^d MANIPAL INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Antimicrobial studies; Imidazoles; Pyrazoles; Toxicity study

Indexed keywords

3 (2,4 DICHLOROPHENYL) 4 (4,5 DIPHENYL 1H IMIDAZOL 2 YL) 1H PYRAZOLE; 3 (2,5 DICHLOROTHIOPHEN 3 YL) 4 (4,5 DIPHENYL 1H IMIDAZOL 2 YL) 1H PYRAZOLE; 3 (BIPHENYL 4 YL) 4 (4,5 DIPHENYL 1H IMIDAZOL 2 YL) 1H PYRAZOLE; 3 (BIPHENYL 4 YL) 4 [4,5 BIS(4 BROMOPHENYL) 1H IMIDAZOL 2 YL] 1H PYRAZOLE; 4 (4,5 DIPHENYL 1H IMIDAZOL 2 YL) 3 (4 METHYLPHENYL) 1H PYRAZOLE; 4 (4,5 DIPHENYL 1H IMIDAZOL 2 YL) 3 [4 (METHYLSULFANYL)PHENYL] 1H PYRAZOLE; 4 [4,5 BIS(4 BROMOPHENYL) 1H IMIDAZOL 2 YL] 3 (2,4 DICHLOROPHENYL) 1H PYRAZOLE; 4 [4,5 BIS(4 BROMOPHENYL) 1H IMIDAZOL 2 YL] 3 (2,5 DICHLOROTHIOPHEN 3 YL) 1H PYRAZOLE; 4 [4,5 BIS(4 BROMOPHENYL) 1H IMIDAZOL 2 YL] 3 (4 METHYLPHENYL) 1H PYRAZOLE; 4 [4,5 BIS(4 BROMOPHENYL) 1H IMIDAZOL 2 YL] 3 [4 (METHYLSULFANYL)PHENYL] 1H PYRAZOLE; ANTIINFECTIVE AGENT; FLUCONAZOLE; IMIDAZOLE DERIVATIVE; M ETHYL 2 [5 OXO 2 THIOXO 3 [[3 (4 TOLYL)] 1H PYRAZOL 4 YL]METHYLENEAMINO]IMIDAZOLIDIN 4 YLIDENE)ACETATE; METHYL 2 [3 [[3 (2,4 DICHLOROPHENYL) 1H PYRAZOL 4 YL]METHYLENEAMINO] 5 OXO 2 THIOXOIMIDAZOLIDIN 4 YLIDENE]ACETATE; METHYL 2 [3 [[3 (2,5 DICHLOROTHIOPHEN 3 YL) 1H PYRAZOL 4 YL]METHYLENEAMINO] 5 OXO 2 THIOXOIMIDAZOLIDIN 4 YLIDENE]ACETATE; METHYL 2 [3 [[3 [4 (METHYLTHIO)PHENYL] 1H PYRAZOL 4 YL]METHYLENEAMINO] 5 OXO 2 THIOXOIMIDAZOLIDIN 4 YLIDENE]ACETATE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTHRODERMA GYPSEUM; ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; CLOSTRIDIUM PERFRINGENS; CONCENTRATION RESPONSE; DRUG POTENCY; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; TRICHOPHYTON RUBRUM;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIAL INFECTIONS; FEMALE; FUNGI; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; IMIDAZOLES; MAXIMUM TOLERATED DOSE; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOSES; PYRAZOLES;

EID: 79958258686     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.05.005     Document Type: Article

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