Hantzsch reaction: Synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents

European Journal of Medicinal Chemistry

Volumn 46, Issue 11, 2011, Pages 5591-5597

  Vijesh, A M ^a,b   Isloor, Arun M ^b   Peethambar, S K ^c   Shivananda, K N ^d   Arulmoli, T ^a   Isloor, Nishitha A ^b  

^a SeQuent Scientific Ltd   (India)

^b NATIONAL INSTITUTE OF TECHNOLOGY KARNATAKA   (India)

^c KUVEMPU UNIVERSITY   (India)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

1,3 Dicarbonylcompounds; 1,4 Dihydropyridine; Antimicrobial studies; Antioxidant studies; Pyrazoles; Toxicity study

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 1,4 DIHYDROPYRIDINE DERIVATIVE; 3 (2,4 DICHLOROPHENYL) 1H PYRAZOLE 4 CARBALDEHYDE; 3 (2,5 DICHLOROTHIOPHEN 3 YL) 1H PYRAZOLE 4 CARBALDEHYDE; 3 [4 (METHYLSULFANYL)PHENYL] 1H PYRAZOLE 4 CARBALDEHYDE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIOXIDANT; DIETHYL 4 [3 (2,4 DICHLOROPHENYL) 1H PYRAZOL 4 Y] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 [3 (2,5 DICHLOROTHIOPHEN 3 YL) 1H PYRAZOL 4 Y] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 Y] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 [3 (BIPHENYL 4 YL) 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 [3 [4 (METHYLSULFANYL)PHENYL] 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIMETHYL 4 [3 (2,4 DICHLOROPHENYL) 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIMETHYL 4 [3 (2,5 DICHLOROTHIOPHEN 3 YL) 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIMETHYL 4 [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIMETHYL 4 [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 Y] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIMETHYL 4 [3 (BIPHENYL 4 YL) 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIMIETHYL 4 [3 [4 (METHYLSULFANYL)PHENYL] 1H PYRAZOL 4 YL] 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SAFETY; DRUG SCREENING; DRUG SYNTHESIS; HANTZSCH REACTION; INFRARED SPECTROSCOPY; LD 50; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TOXICITY TESTING;

ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; BEHAVIOR, ANIMAL; BIPHENYL COMPOUNDS; CHEMISTRY TECHNIQUES, SYNTHETIC; DIHYDROPYRIDINES; FEMALE; FREE RADICAL SCAVENGERS; FUNGI; MICE; PICRATES;

EID: 80054941845     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.09.026     Document Type: Article

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