A fluorescent styrylquinoline with combined therapeutic and diagnostic activities against Alzheimer's and prion diseases

ACS Medicinal Chemistry Letters

Volumn 4, Issue 2, 2013, Pages 225-229

  Staderini, Matteo ^a   Aulić, Suzana ^b   Bartolini, Manuela ^c   Tran, Hoang Ngoc Ai ^b   González Ruiz, Víctor ^a   Pérez, Daniel I ^d   Cabezas, Nieves ^a   Martínez, Ana ^d   Martín, M Antonia ^a   Andrisano, Vincenza ^c   Legname, Giuseppe ^b   Menéndez, J Carlos ^a   Bolognesi, Maria Laura ^c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b SISSA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d INSTITUTO DE QUÍMICA MÉDICA   (Spain)

Author keywords

Aggregation; amyloid; fibrillation inhibitors; protein misfolding diseases

Indexed keywords

6 METHYL 4 AMINO 2 STYRYLQUINOLINE; AMYLOID BETA PROTEIN; CHLOROQUINE; MEFLOQUINE; PRION PROTEIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BETA SHEET; BLOOD BRAIN BARRIER; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIELECTRIC CONSTANT; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; PHARMACOKINETICS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; TREATMENT RESPONSE;

EID: 84873977399     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml3003605     Document Type: Article

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