The role of the Hsp90/Akt pathway in myocardial calpain-induced caspase-3 activation and apoptosis during sepsis

BMC Cardiovascular Disorders

Volumn 13, Issue , 2013, Pages

  Li, Xiaoping ^a,b   Luo, Rong ^c   Jiang, Rongjian ^b   Meng, Xianmin ^a   Wu, Xiushan ^c   Zhang, Shu ^a   Hua, Wei ^a  

^a FUWAI HOSPITAL   (China)

^b SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c HUNAN NORMAL UNIVERSITY   (China)

Author keywords

Apoptosis; Calpain; Caspase 3 activation; Hsp90 Akt; Sepsis

Indexed keywords

CALPAIN; CALPASTATIN; CASPASE 3; HEAT SHOCK PROTEIN 90; LIPOPOLYSACCHARIDE; PD 150606; PROTEIN KINASE B; TANESPIMYCIN; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HEART MUSCLE; MALE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SIGNAL TRANSDUCTION; WILD TYPE;

ACRYLATES; ANDROSTADIENES; ANIMALS; APOPTOSIS; BENZOQUINONES; CALPAIN; CASPASE 3; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HSP90 HEAT-SHOCK PROTEINS; IN SITU NICK-END LABELING; LACTAMS, MACROCYCLIC; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; MYOCARDIUM; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; SEPSIS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84873946023     PISSN: None     EISSN: 14712261     Source Type: Journal    
DOI: 10.1186/1471-2261-13-8     Document Type: Article

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