All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicology and Applied Pharmacology

Volumn 268, Issue 1, 2013, Pages 17-26

  Zhang, Qiang ^a   Kline, Douglas E ^b   Bhattacharya, Sudin ^a   Crawford, Robert B ^b   Conolly, Rory B ^c   Thomas, Russell S ^a   Andersen, Melvin E ^a   Kaminski, Norbert E ^b  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

AhR; All or none; Bach2; Bistable; Feed forward; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; IMMUNOGLOBULIN M; LIPOPOLYSACCHARIDE; PROTEIN BCL 6; RAP1 PROTEIN; TRANSCRIPTION FACTOR PAX5;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CELL FATE; CELL FUNCTION; GENE REGULATORY NETWORK; IN VITRO STUDY; MOUSE; NONHUMAN; PLASMA CELL; SIGNAL TRANSDUCTION;

ADAPTIVE IMMUNITY; ANIMALS; B-LYMPHOCYTES; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; COMPUTER SIMULATION; FEMALE; FLOW CYTOMETRY; IMMUNOGLOBULIN M; MICE; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; RANDOM ALLOCATION; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION FACTOR AP-1;

EID: 84873906214     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.01.015     Document Type: Article

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