Identification of a Drosophila Glucose Receptor Using Ca2+ Imaging of Single Chemosensory Neurons

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Miyamoto, Tetsuya ^a   Chen, Yan ^a   Slone, Jesse ^a,b   Amrein, Hubert ^a  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; GLUCORECEPTOR; GLUCOSE; GUSTATORY RECEPTOR PROTEIN; LIGAND; RECEPTOR PROTEIN; SUGAR; UNCLASSIFIED DRUG;

ANIMAL STRUCTURES; ANIMAL TISSUE; ARTICLE; BITTER TASTE; CALCIUM IMAGING; CHEMOSENSITIVITY; CHEMOSENSORY NEURON; DROSOPHILA MELANOGASTER; FEEDING BEHAVIOR; GUSTATORY RECEPTOR NEURON; IMAGING; NERVE CELL; NERVE CELL STIMULATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FAMILY; TASTE; TASTE BUD; TASTE SENSILLA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ARABINOSE; CALCIUM; CHEMORECEPTOR CELLS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FRUCTOSE; GLUCOSE; LUMINESCENT PROTEINS; MALTOSE; MICROSCOPY, CONFOCAL; MUTATION; NEURONS; RECEPTORS, CELL SURFACE; SENSILLA; SINGLE-CELL ANALYSIS; SUCROSE; TASTE;

EID: 84873896388     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056304     Document Type: Article

References (33)

1. Scott K, (2005) Taste recognition: food for thought. Neuron 48: 455-464.
2. Dahanukar A, Hallem EA, Carlson JR, (2005) Insect chemoreception. Curr Opin Neurobiol 15: 423-430.
3. Amrein H, Thorne N, (2005) Gustatory perception and behavior in Drosophila melanogaster. Curr Biol 15: R673-684.
4. Ishimoto H, Tanimura T, (2004) Molecular neurophysiology of taste in Drosophila. Cell Mol Life Sci 61: 10-18.
5. Tanimura T, Hiroi M, Inoshita T, Marion-Poll F, (2009) Neurophysiology of gustatory receptor neurones in Drosophila. SEB Exp Biol Ser 63: 59-76.
6. Weiss LA, Dahanukar A, Kwon JY, Banerjee D, Carlson JR, (2011) The molecular and cellular basis of bitter taste in Drosophila. Neuron 69: 258-272.
7. Lee Y, Moon SJ, Montell C, (2009) Multiple gustatory receptors required for the caffeine response in Drosophila. Proc Natl Acad Sci U S A 106: 4495-4500.
8. Jiao Y, Moon SJ, Wang X, Ren Q, Montell C, (2008) Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. Curr Biol 18: 1797-1801.
9. Slone J, Daniels J, Amrein H, (2007) Sugar receptors in Drosophila. Curr Biol 17: 1809-1816.
10. Jiao Y, Moon SJ, Montell C, (2007) A Drosophila gustatory receptor required for the responses to sucrose, glucose, and maltose identified by mRNA tagging. Proc Natl Acad Sci U S A 104: 14110-14115.
11. Dahanukar A, Lei YT, Kwon JY, Carlson JR, (2007) Two Gr genes underlie sugar reception in Drosophila. Neuron 56: 503-516.
12. Cameron P, Hiroi M, Ngai J, Scott K, (2010) The molecular basis for water taste in Drosophila. Nature 465: 91-95.
13. Chen Z, Wang Q, Wang Z, (2010) The amiloride-sensitive epithelial Na+ channel PPK28 is essential for drosophila gustatory water reception. J Neurosci 30: 6247-6252.
14. Liu L, Leonard AS, Motto DG, Feller MA, Price MP, et al. (2003) Contribution of Drosophila DEG/ENaC genes to salt taste. Neuron 39: 133-146.
15. Wang Z, Singhvi A, Kong P, Scott K, (2004) Taste representations in the Drosophila brain. Cell 117: 981-991.
16. Thorne N, Chromey C, Bray S, Amrein H, (2004) Taste perception and coding in Drosophila. Curr Biol 14: 1065-1079.
17. Ueno K, Ohta M, Morita H, Mikuni Y, Nakajima S, et al. (2001) Trehalose sensitivity in Drosophila correlates with mutations in and expression of the gustatory receptor gene Gr5a. Curr Biol 11: 1451-1455.
18. Dahanukar A, Foster K, van der Goes van Naters WM, Carlson JR, (2001) A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila. Nat Neurosci 4: 1182-1186.
19. Moon SJ, Lee Y, Jiao Y, Montell C, (2009) A Drosophila gustatory receptor essential for aversive taste and inhibiting male-to-male courtship. Curr Biol 19: 1623-1627.
20. Moon SJ, Kottgen M, Jiao Y, Xu H, Montell C, (2006) A taste receptor required for the caffeine response in vivo. Curr Biol 16: 1812-1817.
21. Meunier N, Marion-Poll F, Rospars JP, Tanimura T, (2003) Peripheral coding of bitter taste in Drosophila. J Neurobiol 56: 139-152.
22. Marella S, Fischler W, Kong P, Asgarian S, Rueckert E, et al. (2006) Imaging taste responses in the fly brain reveals a functional map of taste category and behavior. Neuron 49: 285-295.
23. Fischler W, Kong P, Marella S, Scott K, (2007) The detection of carbonation by the Drosophila gustatory system. Nature 448: 1054-1057.
24. Wang JW, Wong AM, Flores J, Vosshall LB, Axel R, (2003) Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain. Cell 112: 271-282.
25. Fiala A, Spall T, Diegelmann S, Eisermann B, Sachse S, et al. (2002) Genetically Expressed Cameleon in Drosophila melanogaster Is Used to Visualize Olfactory Information in Projection Neurons. Current Biology: Cb 12: 1877-1884.
26. Tian L, Hires SA, Mao T, Huber D, Chiappe ME, et al. (2009) Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat Methods 6: 875-881.
27. Hiroi M, Marion-Poll F, Tanimura T, (2002) Differentiated response to sugars among labellar chemosensilla in Drosophila. Zoolog Sci 19: 1009-1018.
28. Meunier N, Marion-Poll F, Lansky P, Rospars JP, (2003) Estimation of the individual firing frequencies of two neurons recorded with a single electrode. Chem Senses 28: 671-679.
29. Meunier N, Ferveur JF, Marion-Poll F, (2000) Sex-specific non-pheromonal taste receptors in Drosophila. Curr Biol 10: 1583-1586.
30. Croset V, Rytz R, Cummins SF, Budd A, Brawand D, et al. (2010) Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction. PLoS Genet 6: e1001064.
31. Robertson HM, Warr CG, Carlson JR, (2003) Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster. Proc Natl Acad Sci U S A 100 Suppl 2: 14537-14542.
32. Robertson HM, (2009) The insect chemoreceptor superfamily in Drosophila pseudoobscura: molecular evolution of ecologically-relevant genes over 25 million years. J Insect Sci 9: 18.
33. Miyamoto T, Slone J, Song X, Amrein H, (2012) A fructose receptor functions as a nutrient sensor in the Drosophila brain. Cell 151: 1113-1125.