The epigenetic mechanism of mechanically induced osteogenic differentiation

Journal of Biomechanics

Volumn 43, Issue 15, 2010, Pages 2881-2886

  Arnsdorf, Emily J ^a,b   Tummala, Padmaja ^a   Castillo, Alesha B ^a,b   Zhang, Fan ^c   Jacobs, Christopher R ^a,b,d  

^a VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^b Stanford University   (United States)

^c STANFORD UNIVERSITY   (United States)

^d Departments of Microbiology and Immunology ^*  (United States)

Author keywords

Epigenetic; Mechanotransduction; Mesenchymal stem cell; Osteogenic differentiation

Indexed keywords

BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; BONE TISSUE ENGINEERING; CELL DIVISIONS; CELLULAR DIFFERENTIATION; CHROMATIN PROTEINS; DAUGHTER CELLS; DNA METHYLATION; EPIGENETIC; EPIGENETIC MECHANISMS; EPIGENETIC REGULATION; EPIGENETICS; GENE REGULATIONS; GENE SILENCING; MECHANICAL SIGNALS; MECHANICAL STIMULATION; MECHANO-BIOLOGY; MECHANOTRANSDUCTION; MESENCHYMAL STEM CELL; OSTEOGENIC; OSTEOGENIC CELLS; OSTEOGENIC DIFFERENTIATION; PROMOTER REGION; REGENERATIVE MEDICINE; STEM CELL; TISSUE DIFFERENTIATION; TRANSIENT CHANGES;

ALKYLATION; BONE; CELL CULTURE; CELL PROLIFERATION; CHROMOSOMES; DNA; DNA SEQUENCES; GENETIC ENGINEERING; MECHANISMS; METHYLATION; STEM CELLS; TISSUE ENGINEERING; TRANSCRIPTION; TRANSCRIPTION FACTORS;

GENE EXPRESSION REGULATION;

MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN;

ANIMAL CELL; ARTICLE; BONE CELL; BONE TISSUE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL LINEAGE; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE CONTROL; GENE EXPRESSION; GENE SILENCING; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; STEM CELL; TISSUE ENGINEERING; UPREGULATION;

ANIMALS; BASE SEQUENCE; BIOMECHANICS; CELL DIFFERENTIATION; COLLAGEN TYPE I; DNA METHYLATION; DNA PRIMERS; EPIGENESIS, GENETIC; HEMATOPOIETIC STEM CELLS; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; OSTEOCALCIN; OSTEOGENESIS; OSTEOPONTIN; PROMOTER REGIONS, GENETIC;

EID: 78149281847     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2010.07.033     Document Type: Article

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