Deficiencies of the Lipid-Signaling Enzymes Phospholipase D1 and D2 Alter Cytoskeletal Organization, Macrophage Phagocytosis, and Cytokine-Stimulated Neutrophil Recruitment

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Ali, Wahida H ^a   Chen, Qin ^a,e   Delgiorno, Kathleen E ^a,f   Su, Wenjuan ^a   Hall, Jason C ^a,f   Hongu, Tsunaki ^b   Tian, Huasong ^c,d   Kanaho, Yasunori ^b   Di Paolo, Gilbert ^c   Crawford, Howard C ^a,f   Frohman, Michael A ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c Department of Medicine   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^f MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOCK2 PROTEIN; F ACTIN; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDIC ACID; PHOSPHOLIPASE D1; PHOSPHOLIPASE D2; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL ADHESION; CELL MIGRATION; CELL PHAGOCYTOSIS; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LIPODYSTROPHY; MACROPHAGE; MALE; MOLECULAR DYNAMICS; MOUSE; NEUTROPHIL; NEUTROPHIL COUNT; NONHUMAN; PHAGOSOME; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CYTOSKELETON; MACROPHAGES; MICE; NEUROPEPTIDES; NEUTROPHIL INFILTRATION; PANCREATITIS; PHAGOCYTOSIS; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; RAC GTP-BINDING PROTEINS;

EID: 84873801908     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055325     Document Type: Article

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