Cyclooxygenase, cancer stem cells and dna methylation play important roles in colorectal carcinogenesis

Digestion

Volumn 87, Issue 1, 2013, Pages 12-16

  Tsujii, Masahiko ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cancer stem cells; Colorectal cancer; COX 2; Hypermethylation; Hypomethylation; Stemness

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; DNA; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; CELECOXIB; CYCLOOXYGENASE 2; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B;

ANGIOGENESIS; APOPTOSIS; CANCER PREVENTION; CANCER RESISTANCE; CANCER STEM CELL; CANCER THERAPY; CANCER TISSUE; CARCINOGENESIS; CELL INVASION; CELL PROLIFERATION; COLORECTAL CARCINOGENESIS; CONFERENCE PAPER; DNA METHYLATION; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; METASTASIS; PRIORITY JOURNAL; RECURRENT CANCER; CANCER RECURRENCE; COLON CARCINOGENESIS; COLORECTAL CANCER; CYTOLOGY; DRUG RESISTANCE; EPIGENETICS; NONHUMAN;

ANTIGENS, CD; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; NEOPLASTIC STEM CELLS; PEPTIDES;

EID: 84873801718     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000343898     Document Type: Conference Paper

References (24)

1. Lamas MJ, Duran G, Gallardo E: Anti-EGFR therapy in first-line colorectal cancer. Expert Rev Anticancer Ther 2011; 11: 1499-1503
2. Kawai N, Tsujii M, Tsuji S: Cyclooxygenases and colon cancer. Prostaglandins Other Lipid Mediat 2002; 68-69: 187-196
3. Buczacki S, Davies RJ, Winton DJ: Stem cells, quiescence and rectal carcinoma: An unexplored relationship and potential therapeutic target. Br J Cancer 2011; 105: 1253-1259
4. Matsubara N: Epigenetic regulation and colorectal cancer. Dis Colon Rectum 2012; 55: 96-104
5. Xia D, Wang D, Kim SH, Katoh H, DuBois RN: Prostaglandin E2 promotes intestinal tumor growth via DNA methylation. Nat Med 2012; 18: 224-226
6. Miladi-Abdennadher I, Abdelmaksoud-Damak R, Ayadi L, Khabir A, Frikha F, Kallel L, Amouri A, Frikha M, Sellami-Boudawara T, Gargouri A, Mokdad-Gargouri R: Hypermethylation of RAR - 2 correlates with high COX-2 expression and poor prognosis in patients with colorectal carcinoma. Tumour Biol 2010; 31: 503-511
7. Shen R, Tao L, Xu Y, Chang S, Van Brocklyn J, Gao JX: Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer from cancer. Int J Clin Exp Pathol 2009; 2: 21-33
8. Ma HI, Chiou SH, Hueng DY, Tai LK, Huang PI, Kao CL, Chen YW, Sytwu HK: Celecoxib and radioresistant glioblastoma-derived CD133+ cells: improvement in radiotherapeutic effects - laboratory investigation. J Neurosurg 2011; 114: 651-662
9. Annabi B, Laflamme C, Sina A, Lachambre MP, Beliveau R: A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. J Neuroinflammation 2009; 6: 8
10. Ishimoto T, Oshima H, Oshima M, Kai K, Torii R, Masuko T, Baba H, Saya H, Nagano O: CD44+ slow-cycling tumor cell expansion is triggered by cooperative actions of Wnt and prostaglandin E2 in gastric tumorigenesis. Cancer Sci 2010; 101: 673-678
11. Chen KH, Hsu CC, Song WS, Huang CS, Tsai CC, Kuo CD, Hsu HS, Tsai TH, Tsai CY, Woung LC, Chiou SH, Lu KH, Chen YW: Celecoxib enhances radiosensitivity in medulloblastoma- derived CD133-positive cells. Childs Nerv Syst 2010; 26: 1605-1612
12. Singh B, Cook KR, Vincent L, Hall CS, Martin C, Lucci A: Role of COX-2 in tumorospheres derived from a breast cancer cell line. J Surg Res 2011; 168:e39-e49
13. Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ: Chromatin-modifying enzymes as modulators of reprogramming. Nature 2012; 483: 598-602
14. Loriot A, Parvizi GK, Reister S, De Smet C: Silencing of cancer-germline genes in human preimplantation embryos: Evidence for active de novo DNA methylation in stem cells. Biochem Biophys Res Commun 2012; 417: 187-191
15. Yang J, Corsello TR, Ma Y: Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases. J Biol Chem 2012; 287: 1996-2005
16. Trowbridge JJ, Sinha AU, Zhu N, Li M, Armstrong SA, Orkin SH: Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains. Genes Dev 2012; 26: 344-349
17. Trowbridge JJ, Orkin SH: Dnmt3a silences hematopoietic stem cell self-renewal. Nat Genet 2011; 44: 13-14
18. Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, Zern M: Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One 2011; 6:e27740
19. Yu F, Jiao Y, Zhu Y, Wang Y, Zhu J, Cui X, Liu Y, He Y, Park EY, Zhang H, Lv X, Ma K, Su F, Park JH, Song E: MicroRNA 34c gene downregulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells. J Biol Chem 2012; 287: 465-473
20. Zhang RP, Shao JZ, Xiang LX: GADD45A protein plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. J Biol Chem 2011; 286: 41083-41094
21. Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, De Marzo AM, Yegnasubramanian S: Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/ progenitor cell compartments and in human cancers. Oncotarget 2011; 2: 627-637
22. Zhuang J, Jones A, Lee SH, Ng E, Fiegl H, Zikan M, Cibula D, Sargent A, Salvesen HB, Jacobs IJ, Kitchener HC, Teschendorff AE, Widschwendter M: The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer. PLoS Genet 2012; 8:e1002517
23. Nazor KL, Altun G, Lynch C, Tran H, Harness JV, Slavin I, Garitaonandia I, Muller FJ, Wang YC, Boscolo FS, Fakunle E, Dumevska B, Lee S, Park HS, Olee T, D'Lima DD, Semechkin R, Parast MM, Galat V, Laslett AL, Schmidt U, Keirstead HS, Loring JF, Laurent LC: Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. Cell Stem Cell 2012; 10: 620-634
24. Teh MT, Gemenetzidis E, Patel D, Tariq R, Nadir A, Bahta AW, Waseem A, Hutchison IL: Foxm1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma. PLoS One 2012; 7:e34329