-
1
-
-
11844273837
-
Colorectal cancer
-
DOI 10.1016/S0140-6736(05)17706-X, PII S014067360517706X
-
Weitz J, Koch M, Debus J, Hohler T, Galle PR, Büchler M W. Colorectal cancer. Lancet 365(9454), 153-165 (2005). (Pubitemid 40091806)
-
(2005)
Lancet
, vol.365
, Issue.9454
, pp. 153-165
-
-
Weitz, J.1
Koch, M.2
Debus, J.3
Hohler, T.4
Galle, P.R.5
Buchler, M.W.6
-
2
-
-
4644320061
-
Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: Amodel to predict long-term survival
-
Adam R, Delvart V, Pascal G et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: amodel to predict long-term survival. Ann. Surg. 240(4), 644-657 (2004).
-
(2004)
Ann. Surg.
, vol.240
, Issue.4
, pp. 644-657
-
-
Adam, R.1
Delvart, V.2
Pascal, G.3
-
3
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
DOI 10.1200/JCO.2004.05.113
-
Tournigand C, André T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J. Clin. Oncol. 22(2), 229-237 (2004). (Pubitemid 41095086)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.2
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
Lledo, G.4
Flesh, M.5
Mery-Mignard, D.6
Quinaux, E.7
Couteau, C.8
Buyse, M.9
Ganem, G.10
Landi, B.11
Colin, P.12
Louvet, C.13
De Gramont, A.14
-
4
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- refractory metastatic colorectal cancer
-
DOI 10.1056/NEJMoa033025
-
Cunningham D, Humblet Y, Siena S et al. Cetuximab monotherapy and cetuximab plus irinotecan-refractory metastatic colorectal caner. N. Engl. J. Med. 351, 337-345 (2004). (Pubitemid 38944402)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
5
-
-
80054736438
-
Randomized Phase III trial of cetuximab plus irinotecan versus irinotecan alone for metastatic colorectal cancer in 1298 patients who have failed prior oxaliplatin-based therapy: The EPIC trial (Abstract LB-2)
-
Los Angeles, CA, USA 14-18 April
-
Sobrero AF, Fehrenbacher L, Rivera F et al. Randomized Phase III trial of cetuximab plus irinotecan versus irinotecan alone for metastatic colorectal cancer in 1298 patients who have failed prior oxaliplatin-based therapy: the EPIC trial (Abstract LB-2). Presented at: American Association for Cancer Research: 98th Annual Meeting. Los Angeles, CA, USA, 14-18 April 2007.
-
(2007)
Presented At: American Association for Cancer Research: 98th Annual Meeting
-
-
Sobrero, A.F.1
Fehrenbacher, L.2
Rivera, F.3
-
6
-
-
34547196454
-
Randomized Phase III trial of cetuximab monotherapy plus best supportive care (BSC) versus BSC alone in patients with pretreated metastatic epidermal growth factor receptor (EGFR)-positive colorectal carcinoma: A trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) and the Australasian Gastro-Intestinal Trials Group (AGITG) [Abstract LB-1]
-
Los Angeles CA USA 14-18 April
-
Jonker DJ, Karapetis CS, Moore M et al. Randomized Phase III trial of cetuximab monotherapy plus best supportive care (BSC) versus BSC alone in patients with pretreated metastatic epidermal growth factor receptor (EGFR)-positive colorectal carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) and the Australasian Gastro-Intestinal Trials Group (AGITG) [Abstract LB-1]. Presented at: American Association for Cancer Research: 98th Annual Meeting. Los Angeles, CA, USA, 14-18 April 2007.
-
(2007)
Presented At: American Association for Cancer Research: 98th Annual Meeting
-
-
Jonker, D.J.1
Karapetis, C.S.2
Moore, M.3
-
7
-
-
33645284166
-
Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: A single centre Phase II trial
-
Vincenzi B, Santini D, Rabitti C et al. Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre Phase II trial. Br. J. Cancer 94, 792-797 (2006).
-
(2006)
Br. J. Cancer
, vol.94
, pp. 792-797
-
-
Vincenzi, B.1
Santini, D.2
Rabitti, C.3
-
8
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Köhne CH, Hitre E et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N. Engl. J. Med. 360, 1408-1417 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
-
9
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the frst-line treatment of metastatic colorectal cancer
-
Bokemeyer C, Bondarenko I, Makhson A et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the frst-line treatment of metastatic colorectal cancer. J. Clin. Oncol. 27(5), 663-671 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.5
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
-
10
-
-
0343819997
-
Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERB B2, ERB B3) in colorectal adenocarcinomas and adenomas
-
Porebska I, Harlozmska A, Bojarowski T et al. Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERB B2, ERB B3) in colorectal adenocarcinomas and adenomas. Tumor Biol. 21(2), 105-115 (2000). (Pubitemid 30114656)
-
(2000)
Tumor Biology
, vol.21
, Issue.2
, pp. 105-115
-
-
Porebska, I.1
Harlozinska, A.2
Bojarowski, T.3
-
11
-
-
42649145667
-
Wild-type KRAS is required for panitumumab effcacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M et al. Wild-type KRAS is required for panitumumab effcacy in patients with metastatic colorectal cancer. J. Clin. Oncol. 26(10), 1626-1634 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.10
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
12
-
-
77955230826
-
Cetuximab with chemotherapy (CT) as frst-line treatment for metastatic colorectal cancer (mCRC): A meta-analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status. ASCO (Abstract 406)
-
Orlando, FL, USA 22-24 January
-
Kohne C, Rougier P, Stroh C et al Cetuximab with chemotherapy (CT) as frst-line treatment for metastatic colorectal cancer (mCRC): a meta-analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status. ASCO (Abstract 406). Presented at: Gastrointestinal Cancers Symposium. Orlando, FL, USA, 22-24 January 2010
-
(2010)
Presented At: Gastrointestinal Cancers Symposium
-
-
Kohne, C.1
Rougier, P.2
Stroh, C.3
-
13
-
-
79959616846
-
Impact of early tumor shrinkage on long-term outcome in metastatic colorectal cancer (mCRC) treated with FOLFOX4 with or without cetuximab: Lessons from the OPUS trial
-
Impact of early tumor shrinkage on long-term outcome in metastatic colorectal cancer (mCRC) treated with FOLFOX4 with or without cetuximab: lessons from the OPUS trial. J. Clin. Oncol. 29(Suppl. 4) (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.SUPPL. 4
-
-
-
14
-
-
60149091085
-
Randomized multicenter study of cetuximab plus FOLFOX or cetuximab plus FOLFIRI in neoadjuvant treatment of non-resectable colorectal liver metastases (CLM)
-
Abstract 510PD
-
Folprecht G, Gruenberger T, Hartmann JT et al. Randomized multicenter study of cetuximab plus FOLFOX or cetuximab plus FOLFIRI in neoadjuvant treatment of non-resectable colorectal liver metastases (CLM). Ann. Oncol. 19(8), 168 (2008) (Abstract 510PD).
-
(2008)
Ann. Oncol.
, vol.19
, Issue.8
, pp. 168
-
-
Folprecht, G.1
Gruenberger, T.2
Hartmann, J.T.3
-
15
-
-
84875006883
-
Cetuximab weekly (q1w) versus every two weeks (q2w) plus FOLFOX4 as frst-line therapy in patients (pts) with KRA S wild-type (wt) metastatic colorectal cancer (mCRC)
-
Abstract 494
-
Ciuleanu T, Nikolic V, Shmueli E et al Cetuximab weekly (q1w) versus every two weeks (q2w) plus FOLFOX4 as frst-line therapy in patients (pts) with KRA S wild-type (wt) metastatic colorectal cancer (mCRC). J. Clin. Oncol. 29(Suppl. 4) (2011) (Abstract 494).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.SUPPL. 4
-
-
Ciuleanu, T.1
Nikolic, V.2
Shmueli, E.3
-
16
-
-
73349094741
-
Analysis of PTEN BRAF, and EGFR status in determining beneft from cetuximab therapy in wild-type KRAS metastatic colon cancer
-
Laurent-Puig, Cayre A, Manceau G et al Analysis of PTEN, BRAF, and EGFR status in determining beneft from cetuximab therapy in wild-type KRAS metastatic colon cancer. J. Clin. Oncol. 27(35), 5924-5930 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.35
, pp. 5924-5930
-
-
Laurent-Puig1
Cayre, A.2
Manceau, G.3
-
17
-
-
78049341541
-
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
-
De Roock W, Jonker D, Di Nicolantonio F et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA 304(16), 1812-1820 (2010).
-
(2010)
JAMA
, vol.304
, Issue.16
, pp. 1812-1820
-
-
De Roock, W.1
Jonker, D.2
Di Nicolantonio, F.3
-
18
-
-
0024536437
-
Optimal two-stage designs for phase II clinical trials
-
DOI 10.1016/0197-2456(89)90015-9
-
Simon R. Optimal two-stage designs for Phase II clinical trials. Control. Clin. Trials 10(1), 1-10 (1989). (Pubitemid 19099520)
-
(1989)
Controlled Clinical Trials
, vol.10
, Issue.1
, pp. 1-10
-
-
Simon, R.1
-
19
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the effcacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
-
De Roock W, Claes B, Bernasconi D et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the effcacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol. 11(8), 753-762 (2010).
-
(2010)
Lancet Oncol.
, vol.11
, Issue.8
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
-
20
-
-
74249093155
-
PTEN status in advanced colorectal cancer treated with cetuximab
-
Negri FV, Bozzetti C, Lagrasta CA et al. PTEN status in advanced colorectal cancer treated with cetuximab. Br. J. Cancer 102(1), 162-164 (2010).
-
(2010)
Br. J. Cancer
, vol.102
, Issue.1
, pp. 162-164
-
-
Negri, F.V.1
Bozzetti, C.2
Lagrasta, C.A.3
-
21
-
-
79953250126
-
Use of a comprehensive panel of biomarkers to predict response to a fuorouracil-oxaliplatin regimen in patients with metastatic colorectal cancer
-
Lamas MJ, Duran G, Balboa E et al. Use of a comprehensive panel of biomarkers to predict response to a fuorouracil-oxaliplatin regimen in patients with metastatic colorectal cancer. Pharmacogenomics 12(3), 433-442 (2011).
-
(2011)
Pharmacogenomics
, vol.12
, Issue.3
, pp. 433-442
-
-
Lamas, M.J.1
Duran, G.2
Balboa, E.3
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