Effect of DOPE and cholesterol on the protein adsorption onto lipid nanoparticles

Journal of Nanoparticle Research

Volumn 15, Issue 3, 2013, Pages

  Caracciolo, Giulio ^a   Pozzi, Daniela ^a   Capriotti, Anna Laura ^b   Cavaliere, Chiara ^b   Laganà, Aldo ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Cationic liposomes; Drug delivery; Lipid nanoparticles; Nano liquid chromatography tandem mass spectrometry; Protein corona; Proteomics

Indexed keywords

ADSORPTION; CHOLESTEROL; LIPIDS; LIPOSOMES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NANOPARTICLES; PROTEINS; PROTEOMICS;

CATIONIC LIPOSOMES; HUMAN PLASMA PROTEINS; LIPID NANOPARTICLES; NANO LIQUID CHROMATOGRAPHY; PREFERENTIAL BINDING; PROTEIN CORONAS; PROTEIN INTERACTION; TRANSFECTION EFFICIENCY;

DRUG DELIVERY;

APOLIPOPROTEIN; CHOLESTEROL; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; IMMUNOGLOBULIN; LIPID; LIPOSOME; NANOPARTICLE; PROTEIN; PROTHROMBIN; RUSALATIDE;

ADSORPTION; ARTICLE; CIRCULATION; GENETIC TRANSFECTION; HUMAN; LIPID COMPOSITION; LIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION;

EID: 84873744700     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-013-1498-4     Document Type: Article

References (63)

1. Abe Y, Kuroda Y, Kuboki N, Matsushita M, Yokoyama N, Kojima N (2008) Contribution of complement component C3 and complement receptor type 3 to carbohydrate-dependent uptake of oligomannose-coated liposomes by peritoneal macrophages. J Biochem 144:563-570
2. Allen TM, Cullis PR (2004) Drug delivery systems: entering the mainstream. Science 303:1818e22 (Pubitemid 38374867)
3. Amenitsch H, Caracciolo G, Foglia P, Fuscoletti V, Giansanti P, Marianecci C, Pozzi D, Laganà A (2011) Existence of hybrid structures in cationic liposome/DNA complexes revealed by their interaction with plasma proteins. Colloids Surf B 82:141-146
4. Bisgaier CL, Siebenkas MV, Williams KJ (1989) Effects of apolipoproteins A-IV and A-I on the uptake of phospholipid liposomes by hepatocytes. J Biol Chem 264:862-866 (Pubitemid 19038065)
5. Caminiti R, Caracciolo G, Pisani M (2005) Effect of hydration on the structure of oriented lipid membranes investigated by in situ time-resolved Energy Dispersive X-ray Diffraction. Appl Phys Lett 86:253902-253904 (Pubitemid 41244112)
6. Capriotti AL, Caracciolo G, Caruso G, Cavaliere C, Pozzi D, Samperi R, Laganà A (2010) Analysis of plasma proteins adsorption onto DC-Chol-DOPE cationic liposomes by HPLC-CHIP coupled to a Q-TOF mass spectrometer. Anal Bioanal Chem 398:2895-2903
7. Capriotti AL, Caracciolo G, Caruso G, Foglia P, Pozzi D, Samperi R, Laganà A (2011a) Differential analysis of "protein corona" profile adsorbed onto different nonviral gene delivery systems. Anal Biochem 419:180-189
8. Capriotti AL, Caracciolo G, Caruso G, Foglia P, Pozzi D, Samperi R, Laganà A (2011b) DNA affects the composition of lipoplex protein corona: a proteomics approach. Proteomics 11:3349-3358
9. Capriotti AL, Caracciolo G, Cavaliere C, Crescenzi C, Pozzi D, Laganà A (2011c) Shotgun proteomics analytical approach for studying proteins adsorbed onto liposome surface. Anal Bioanal Chem 401:1195-1202
10. Capriotti AL, Caracciolo G, Caruso G, Cavaliere C, Pozzi D, Samperi R, Laganà A (2012a) Label-free quantitative analysis for studying the interactions between nanoparticles and plasma proteins. Anal Bioanal Chem. doi: 10.1007/s00216-011-5691-y
11. Capriotti AL, Caracciolo G, Cavaliere C, Foglia P, Pozzi D, Samperi R, Laganà A (2012b) Do plasma proteins distinguish between liposomes of varying charge density? J Proteomics 75:1924-1932
12. Caracciolo G (2012) The protein corona effect for targeted drug delivery. Bioinspired Biomim Nanobiomater. doi: 10.1680/bbn.12.00027
13. Caracciolo G, Caminiti R (2005) Do DC-Chol/DOPE-DNA complexes really form an inverted hexagonal phase? Chem Phys Lett 411:327-332 (Pubitemid 41042424)
14. Caracciolo G, Caminiti R, Pozzi D, Friello M, Boffi F, Congiu Castellano A (2002) Self-Assembly of cationic liposomes-DNA: a structural and thermodynamic study by Energy Dispersive X-ray Diffraction. Chem Phys Lett 351:222-228
15. Caracciolo G, Pozzi D, Amenitsch H, Caminiti R (2006) One dimensional thermotropic dilatation area of lipid headgroups within lamellar lipoplexes. Langmuir 22:4267-4273
16. Caracciolo G, Pozzi D, Amenitsch H, Caminiti R (2007) Interaction between lipoplexes and cellular lipids resulting in DNA release is a two-stage process. Langmuir 23:8713-8717 (Pubitemid 47294276)
17. Caracciolo G, Pozzi D, Caminiti R, Marchini C, Montani M, Amici A, Amenitsch H (2008) Enhanced transfection efficiency of multicomponent lipoplexes in the regime of optimal membrane charge density. J Phys Chem B 112:11298-11304
18. Caracciolo G, Caminiti R, Digman MA, Gratton E, Sanchez S (2009) Efficient escape from endosomes determines the superior efficiency of multicomponent lipoplexes. J Phys Chem B 113:4995-4997
19. Caracciolo G, Pozzi D, Capriotti AL, Marianecci C, Carafa M, Marchini C, Montani M, Amici A, Amenitsch H, Digman MA, Gratton E, Sanchez SS, Laganà A (2011a) Factors determining the superior performance of lipid/DNA/protammine nanoparticles over lipoplexes. J Med Chem 54:4160-4171
20. Caracciolo G, Pozzi D, Candeloro De Sanctis S, Capriotti AL, Caruso G, Samperi R, Laganà A (2011b) Effect of membrane charge density on the protein corona of cationic liposomes: interplay between cationic charge and surface area. Appl Phys Lett 99:033702
21. Caracciolo G, Pozzi D, Capriotti AL, Cavaliere C, Cardarelli F, Bifone A, Bardi G, Salomone F, Laganà A (2012) Cancer cell targeting of lipid gene vectors by protein corona. In: Nanotech Conference and Expo 2012: technical proceedings of the 2012 NSTI nanotechnology conference and expo, 18-21 June 2012. Santa Clara Convention Center, Santa Clara, pp 354-357
22. Cedervall T, Lynch I, Foy M, Berggard T, Donnelly SC, Cagney G, Linse S, Dawson KA (2007) Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angew Chem Int Ed 46:5754-5756 (Pubitemid 47172204)
23. Dell'Orco D, Lundqvist M, Oslakovic C, Cedervall T, Linse S (2010) Modeling the time evolution of the nanoparticle-protein corona in a body fluid. PLoS ONE 5(6):e10949
24. Duncan B, Kim C, Rotello VM (2010) Gold nanoparticle platforms as drug and biomacromolecule delivery systems. J Control Release 148:122-127
25. Even-Chen S, Cohen R, Barenholz Y (2012) Factors affecting DNA binding and stability of association to cationic liposomes. Chem Phys Lipids 165:414-423
26. Frisken BJ (2001) Revisiting the method of cumulants for the analysis of dynamic light-scattering data. Appl Opt 40:4087-4091
27. Gessner A, Lieske A, Paulke B, Müller R (2002) Influence of surface charge density on protein adsorption on polymeric nanoparticles: analysis by two-dimensional electrophoresis. Eur J Pharm Biopharm 54:165-170 (Pubitemid 34919390)
28. Gessner A, Lieske A, Paulke BR, Muller RH (2003) Functional groups on polystyrene model nanoparticles: influence on protein adsorption. J Biomed Mater Res A 65:319-326 (Pubitemid 37517267)
29. Gjetting T, Arildsen NS, Christensen CL, Poulsen TT, Roth JA, Handlos VN, Poulsen HS (2010) In vitro and in vivo effects of polyethylene glycol mediated gene transfection. Int J Nanomed 5:371-383
30. Han G, Ghosh P, De M, Rotello VM (2007a) Drug and gene delivery using gold nanoparticles. Nanobiotechnology 3:40-45 (Pubitemid 350135993)
31. Han G, Ghosh P, Rotello VM (2007b) Functionalized gold nanoparticles for drug delivery. Nanomedicine 2:113-123 (Pubitemid 46845782)
32. Ishida T, Kojima H, Harashima H, Kiwada H (2000) Biodistribution of liposomes and C3 fragments associated with liposomes: evaluation of their relationship. Int J Pharm 205:183-193
33. Ishida T, Harashima H, Kiwada H (2002) Liposome clearance. Biosci Rep 22:197-224 (Pubitemid 35222732)
34. Kim S, Shin D, Lee H, Ahn B-Y, Yoon Y, Kim M (2009) Targeted delivery of siRNA against hepatitis C virus by apolipoprotein A-I-bound cationic liposomes. J Hepatol 50:479-488
35. Kim SK, Foote MB, Huang L (2012) The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles. Biomaterials 33:3959-3966
36. Kuntsche J, Horst JC, Bunjes H (2011) Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems. Int J Pharm 417:120-137
37. Kwon OJ, Kang E, Kim S, Yun CO (2011) Viral genome DNA/lipoplexes elicit in situ oncolytic viral replication and potent antitumor efficacy via systemic delivery. J Control Release 155:317-325
38. Lesniak A, Campbell A, Monopoli M, Lynch I, Salvati A, Dawson KA (2010) Serum heat inactivation affects protein corona composition and nanoparticle uptake. Biomaterials 36:9511-9518
39. Lundqvist M, Stigler J, Cedervall T, Elia G, Lynch I, Dawson KA (2008) Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci USA 105:14265-14270
40. Lundqvist M, Stigler J, Cedervall T, Berggård T, Flanagan MB, Lynch I, Elia G, Dawson KA (2011) The evolution of the protein corona around nanoparticles: a test study. ACS Nano 5:7503-7509
41. Lynch I, Dawson KA (2008) Protein-nanoparticle interactions. Nano Today 3:40-47 (Pubitemid 351298587)
42. Lynch I, Cedervall T, Lundqvist M, Cabaleiro-Lago C, Linse S, Dawson KA (2007) The nanoparticle-protein complex as a biological entity; a complex fluids and surface science challenge for the 21st century. Adv Colloid Interface Sci 134-135:167-174 (Pubitemid 47614904)
43. Mahon E, Salvati A, Baldelli Bombelli F, Lynch I, Dawson KA (2012) Designing the nanoparticle-biomolecule interface for "targeting and therapeutic delivery". J Control Release 161:164-174
44. Marchini C, Pozzi D, Montani M, Alfonsi C, Amici A, Candeloro De Sanctis S, Digman MA, Sanchez S, Gratton E, Amenitsch H, Fabbretti A, Gualerzi CO, Caracciolo G (2011) Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes. Cancer Gene Ther 18:543-552
45. McLaughlin S, Whitaker M (1988) Cations that alter surface potentials of lipid bilayers increase the calcium requirement for exocytosis in sea urchin eggs. J Physiol 396:189-204 (Pubitemid 18027904)
46. Moghimi SM, Patel HM (1988) Tissue specific opsonins for phagocytic cells and their different affinity for cholesterol-rich liposomes. FEBS Lett 233:143-147
47. Monopoli MP, Baldelli Bombelli F, Dawson KA (2011a) Nanobiotechnology: nanoparticle coronas take shape. Nat Nanotechnol 6:11-12
48. Monopoli MP, Walczyk D, Campbell A, Elia G, Lynch I, Baldelli Bombelli F, Dawson KA (2011b) Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J Am Chem Soc 133:2525-2534
49. Morita SY, Sakurai A, Nakano M, Kitagawa S, Handa T (2011) Presence of apolipoprotein C-III attenuates apolipoprotein E-mediated cellular uptake of cholesterol-containing lipid particles by HepG2 cells. Lipids 46:323-332
50. Pitek AS, O'Connell D, Mahon E, Monopoli MP, Baldelli Bombelli F, Dawson KA (2012) Transferrin coated nanoparticles: study of the bionano interface in human plasma. PLoS ONE 7:e40685
51. Pozzi D, Amenitsch H, Caminiti R, Caracciolo G (2006) How lipid hydration and temperature affect the structure of DC-Chol/DOPE/DNA lipoplexes. Chem Phys Lett 422:439-445
52. Pozzi D, Marchini C, Cardarelli F, Amenitsch H, Garulli C, Bifone A, Caracciolo G (2012) Transfection efficiency boost of cholesterol-containing lipoplexes. Biochim Biophys Acta 1818:2335-2343
53. Puri A, Loomis K, Smith B, Lee J-H, Yavlovich A, Heldman E, Blumenthal R (2009) Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic. Crit Rev Ther Drug Carr Syst 26:523-580
54. Sandin P, Fitzpatrick LW, Simpson JC, Dawson KA (2012) High-speed imaging of rab family small GTpases reveals rare events in nanoparticle trafficking in living cells. ACS Nano 6:1513-1521
55. Scieszka JF, Maggiora LL, Wright SD, Cho MJ (1991) Role of complements C3 and C5 in the phagocytosis of liposomes by human neutrophils. Pharm Res 8:65-69
56. Simberg D, Danino D, Talmon Y, Minsky A, Ferrari ME, Wheeler CJ, Barenholz Y (2001) Phase behavior, DNA ordering, and size instability of cationic lipoplexes relevance to optimal transfection activity. J Biol Chem 276:47453-47459
57. Simberg D, Weisman S, Talmon Y, Faerman A, Shoshani T, Barenholz Y (2003) The role of organ vascularization and lipoplex-serum initial contact in intravenous murine lipofection. J Biol Chem 278:39858-39865 (Pubitemid 37248548)
58. Simberg D, Weiss A, Barenholz Y (2005) Reversible mode of binding of serum proteins to DOTAP/cholesterol lipoplexes: a possible explanation for intravenous lipofection efficiency. Hum Gene Ther 16:1087-1096 (Pubitemid 41324568)
59. Stark WJ (2011) Nanoparticles in biological systems. Angew Chem Int Ed Engl 50:1242e58
60. Wagner A, Vorauer-Uhl K (2011) Liposome technology for industrial purposes. J Drug Deliv 2011:591325
61. Williams KJ, Werth VP, Wolff JA (1984) Intravenously administered lecithin liposomes: a synthetic antiatherogenic lipid particle. Perspect Biol Med 27:417-431
62. Yoshikawa N, Sakamoto K, Mizuno S, Sakaguchi J, Miyamoto H, Mine T, Sasaki H, Fumoto S, Nishida K (2011) Multiple components in serum contribute to hepatic transgene expression by lipoplex in mice. J Gene Med 13:632-643
63. Zybailov B, Mosley AL, Sardiu ME, Coleman MK, Florens L, Washburn MP (2006) Statistical analysis of membrane proteome expression changes in Saccharomyces cerevisiae. J Proteome Res 5:2339-2347 (Pubitemid 44330827)