메뉴 건너뛰기




Volumn 133, Issue 3, 2013, Pages 647-657

Increased KGF expression promotes fibroblast activation in a double paracrine manner resulting in cutaneous fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; KERATINOCYTE GROWTH FACTOR; ONCOSTATIN M; STAT3 PROTEIN; UROKINASE;

EID: 84873743763     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.389     Document Type: Article
Times cited : (72)

References (42)
  • 1
    • 77955713805 scopus 로고    scopus 로고
    • Epithelial cells promote fibroblast activation via IL-1a in systemic sclerosis
    • Available at (accessed 17 June 2010
    • Aden N, Nuttall A, Shiwen X et al. (2010) Epithelial cells promote fibroblast activation via IL-1a in systemic sclerosis. J Invest Dermatol. Available at: http://dx.doi.org/10.1038/jid.2010.120, (accessed 17 June 2010
    • J Invest Dermatol , vol.2010
    • Aden, N.1    Nuttall, A.2    Shiwen, X.3
  • 2
    • 0034517417 scopus 로고    scopus 로고
    • Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair
    • Beer HD, Gassmann MG, Munz B et al. (2000) Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair. J Investig Dermatol Symp Proc 5: 34-9
    • (2000) J Investig Dermatol Symp Proc , vol.5 , pp. 34-39
    • Beer, H.D.1    Gassmann, M.G.2    Munz, B.3
  • 3
    • 79960228013 scopus 로고    scopus 로고
    • CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
    • Braig S, Wallner S, Junglas B et al. (2011) CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration. Br J Cancer 105: 231-8
    • (2011) Br J Cancer , vol.105 , pp. 231-238
    • Braig, S.1    Wallner, S.2    Junglas, B.3
  • 4
    • 70349576542 scopus 로고    scopus 로고
    • Keloids: Current concepts of pathogenesis (review
    • Bran GM, Goessler UR, Hormann K et al. (2009) Keloids: current concepts of pathogenesis (review). Int J Mol Med 24: 283-93
    • (2009) Int J Mol Med , vol.24 , pp. 283-293
    • Bran, G.M.1    Goessler, U.R.2    Hormann, K.3
  • 5
    • 38049092798 scopus 로고    scopus 로고
    • Use of organotypic coculture to study keloid biology
    • Butler PD, Ly DP, Longaker MT et al. (2008) Use of organotypic coculture to study keloid biology. Am J Surg 195: 144-8
    • (2008) Am J Surg , vol.195 , pp. 144-148
    • Butler, P.D.1    Ly, D.P.2    Longaker, M.T.3
  • 6
    • 0038753847 scopus 로고    scopus 로고
    • Decreased expression of fibroblast and keratinocyte growth factor isoforms and receptors during scarless repair
    • Dang CM, Beanes SR, Soo C et al. (2003) Decreased expression of fibroblast and keratinocyte growth factor isoforms and receptors during scarless repair. Plast Reconstr Surg 111: 1969-79
    • (2003) Plast Reconstr Surg , vol.111 , pp. 1969-1979
    • Dang, C.M.1    Beanes, S.R.2    Soo, C.3
  • 7
    • 19444385692 scopus 로고    scopus 로고
    • Stat3 regulates genes common to both wound healing and cancer
    • Dauer DJ, Ferraro B, Song L et al. (2005) Stat3 regulates genes common to both wound healing and cancer. Oncogene 24: 3397-408
    • (2005) Oncogene , vol.24 , pp. 3397-3408
    • Dauer, D.J.1    Ferraro, B.2    Song, L.3
  • 8
  • 9
    • 78649329385 scopus 로고    scopus 로고
    • Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: Implications for development of a novel treatment option
    • Dienus K, Bayat A, Gilmore BF et al. (2010) Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option. Arch Dermatol Res 302: 725-31
    • (2010) Arch Dermatol Res , vol.302 , pp. 725-731
    • Dienus, K.1    Bayat, A.2    Gilmore, B.F.3
  • 10
    • 19944426746 scopus 로고    scopus 로고
    • Interleukin-6-type cytokines upregulate expression of multidrug resistance-associated proteins in NHEK and dermal fibroblasts
    • Dreuw A, Hermanns HM, Heise R et al. (2005) Interleukin-6-type cytokines upregulate expression of multidrug resistance-associated proteins in NHEK and dermal fibroblasts. J Invest Dermatol 124: 28-37
    • (2005) J Invest Dermatol , vol.124 , pp. 28-37
    • Dreuw, A.1    Hermanns, H.M.2    Heise, R.3
  • 11
    • 0027468283 scopus 로고
    • Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice
    • Guo L, Yu QC, Fuchs E (1993) Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. EMBO J 12: 973-86
    • (1993) EMBO J , vol.12 , pp. 973-986
    • Guo, L.1    Yu, Q.C.2    Fuchs, E.3
  • 12
    • 84860376241 scopus 로고    scopus 로고
    • Fibroproliferative disorders and their mechanobiology
    • Available at accessed 28 March 2012
    • Huang C, Ogawa R (2012) Fibroproliferative disorders and their mechanobiology. Connect Tissue Res. Available at: http://www.ncbi.nlm.nih.gov/ pubmed/22329637, (accessed 28 March 2012).
    • (2012) Connect Tissue Res
    • Huang, C.1    Ogawa, R.2
  • 13
    • 0033079839 scopus 로고    scopus 로고
    • Keratinocyte growth factor-2 accelerates wound healing in incisional wounds
    • Jimenez PA, Rampy MA (1999) Keratinocyte growth factor-2 accelerates wound healing in incisional wounds. J Surg Res 81: 238-42
    • (1999) J Surg Res , vol.81 , pp. 238-242
    • Jimenez, P.A.1    Rampy, M.A.2
  • 14
    • 0020330066 scopus 로고
    • Hypertrophic scars and keloids: A review and new concept concerning their origin
    • Kischer CW, Shetlar MR, Chvapil M (1982) Hypertrophic scars and keloids: a review and new concept concerning their origin. Scan Electron Microsc 1699-713
    • (1982) Scan Electron Microsc , pp. 1699-1713
    • Kischer, C.W.1    Shetlar, M.R.2    Chvapil, M.3
  • 15
    • 35349030411 scopus 로고    scopus 로고
    • Fibrosis in connective tissue disease: The role of the myofibroblast and fibroblast-epithelial cell interactions
    • Krieg T, Abraham D, Lafyatis R (2007) Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions. Arthritis Res Ther 9(Suppl 2): S4
    • (2007) Arthritis Res Ther , vol.9 , Issue.SUPPL. 2
    • Krieg, T.1    Abraham, D.2    Lafyatis, R.3
  • 16
    • 0346220301 scopus 로고    scopus 로고
    • Expression of urokinase-type plasminogen activator and its receptor in keloids
    • Leake D, Doerr TD, Scott G (2003) Expression of urokinase-type plasminogen activator and its receptor in keloids. Arch Otolaryngol Head Neck Surg 129: 1334-8
    • (2003) Arch Otolaryngol Head Neck Surg , vol.129 , pp. 1334-1338
    • Leake, D.1    Doerr, T.D.2    Scott, G.3
  • 17
    • 58649106210 scopus 로고    scopus 로고
    • An in vitro analysis of mechanical wounding-induced ligand-independent KGFR activation
    • Li M, Firth JD, Putnins EE (2009) An in vitro analysis of mechanical wounding-induced ligand-independent KGFR activation. J Dermatol Sci 53: 182-91
    • (2009) J Dermatol Sci , vol.53 , pp. 182-191
    • Li, M.1    Firth, J.D.2    Putnins, E.E.3
  • 18
    • 33748312072 scopus 로고    scopus 로고
    • Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration
    • Lim CP, Phan T-T, Lim IJ et al. (2006) Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration. Oncogene 25: 5416-25
    • (2006) Oncogene , vol.25 , pp. 5416-5425
    • Lim, C.P.1    Phan, T.-T.2    Lim, I.J.3
  • 19
    • 63149096121 scopus 로고    scopus 로고
    • Cytokine profiling and Stat3 phosphorylation in epithelial-mesenchymal interactions between keloid keratinocytes and fibroblasts
    • Lim CP, Phan TT, Lim IJ et al. (2009) Cytokine profiling and Stat3 phosphorylation in epithelial-mesenchymal interactions between keloid keratinocytes and fibroblasts. J Invest Dermatol 129: 851-61
    • (2009) J Invest Dermatol , vol.129 , pp. 851-861
    • Lim, C.P.1    Phan, T.T.2    Lim, I.J.3
  • 20
    • 0032768526 scopus 로고    scopus 로고
    • Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism
    • Maas-Szabowski N, Shimotoyodome A, Fusenig NE (1999) Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism. J Cell Sci 112(Pt 12): 1843-53
    • (1999) J Cell Sci , vol.112 , Issue.PART 12 , pp. 1843-1853
    • Maas-Szabowski, N.1    Shimotoyodome, A.2    Fusenig, N.E.3
  • 21
    • 0026570847 scopus 로고
    • Determination of ligandbinding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene
    • Miki T, Bottaro DP, Fleming TP et al. (1992) Determination of ligandbinding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci USA 89: 246-50
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 246-250
    • Miki, T.1    Bottaro, D.P.2    Fleming, T.P.3
  • 22
    • 84856076539 scopus 로고    scopus 로고
    • Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced Collagen synthesis and resultant hypertrophy in rat heart
    • Mir SA, Chatterjee A, Mitra A et al. (2012) Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced Collagen synthesis and resultant hypertrophy in rat heart. J Biol Chem 287: 2666-77
    • (2012) J Biol Chem , vol.287 , pp. 2666-2677
    • Mir, S.A.1    Chatterjee, A.2    Mitra, A.3
  • 23
    • 58149198189 scopus 로고    scopus 로고
    • Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis
    • Mozaffarian A, Brewer AW, Trueblood ES et al. (2008) Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis. J Immunol 181: 7243-53
    • (2008) J Immunol , vol.181 , pp. 7243-7253
    • Mozaffarian, A.1    Brewer, A.W.2    Trueblood, E.S.3
  • 24
    • 34250352380 scopus 로고    scopus 로고
    • Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors
    • Niu J, Chang Z, Peng B et al. (2007) Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J Biol Chem 282: 6001-11
    • (2007) J Biol Chem , vol.282 , pp. 6001-6011
    • Niu, J.1    Chang, Z.2    Peng, B.3
  • 25
    • 77952739230 scopus 로고    scopus 로고
    • Comparative proteomic analysis between normal skin and keloid scar
    • Ong CT, Khoo YT, Mukhopadhyay A et al. (2010) Comparative proteomic analysis between normal skin and keloid scar. Br J Dermatol 162: 1302-15
    • (2010) Br J Dermatol , vol.162 , pp. 1302-1315
    • Ong, C.T.1    Khoo, Y.T.2    Mukhopadhyay, A.3
  • 26
    • 77954730368 scopus 로고    scopus 로고
    • A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy
    • Pang M, Ma L, Gong R et al. (2010) A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy. Kidney Int 78: 257-68
    • (2010) Kidney Int , vol.78 , pp. 257-268
    • Pang, M.1    Ma, L.2    Gong, R.3
  • 27
    • 51749085805 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway
    • Park G, Yoon BS, Moon J-H et al. (2008) Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway. J Invest Dermatol 128: 2429-41
    • (2008) J Invest Dermatol , vol.128 , pp. 2429-2441
    • Park, G.1    Yoon, B.S.2    Moon, J.-H.3
  • 28
    • 84859015820 scopus 로고    scopus 로고
    • STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF
    • Available at accessed 18 February 2012
    • Pechkovsky DV, Prêle CM, Wong J et al. (2012) STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF. Am J Pathol. Available at: http://www.ncbi.nlm.nih. gov/pubmed/22322297, (accessed 18 February 2012
    • (2012) Am J Pathol
    • Pechkovsky, D.V.1    Prêle, C.M.2    Wong, J.3
  • 29
    • 0036233318 scopus 로고    scopus 로고
    • Differences in collagen production between normal and keloid-derived fibroblasts in serum-media co-culture with keloid-derived keratinocytes
    • Phan T-T, Lim IJ, Bay B-H et al. (2002) Differences in collagen production between normal and keloid-derived fibroblasts in serum-media co-culture with keloid-derived keratinocytes. J Dermatol Sci 29: 26-34
    • (2002) J Dermatol Sci , vol.29 , pp. 26-34
    • Phan, T.-T.1    Lim, I.J.2    Bay, B.-H.3
  • 30
    • 78149269955 scopus 로고    scopus 로고
    • The plasminogen activator system in fibroblasts from systemic sclerosis
    • Postiglione L, Montuori N, Riccio A et al. (2010) The plasminogen activator system in fibroblasts from systemic sclerosis. Int J Immunopathol Pharmacol 23: 891-900
    • (2010) Int J Immunopathol Pharmacol , vol.23 , pp. 891-900
    • Postiglione, L.1    Montuori, N.2    Riccio, A.3
  • 32
    • 0035987792 scopus 로고    scopus 로고
    • Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts
    • Scaffidi AK, Mutsaers SE, Moodley YP et al. (2002) Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts. Br J Pharmacol 136: 793-801
    • (2002) Br J Pharmacol , vol.136 , pp. 793-801
    • Scaffidi, A.K.1    Mutsaers, S.E.2    Moodley, Y.P.3
  • 33
    • 25444457220 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: An epithelial/fibroblastic cross-talk disorder
    • Selman M, Pardo A (2002) Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder. Respir Res 3: 3
    • (2002) Respir Res , vol.3 , pp. 3
    • Selman, M.1    Pardo, A.2
  • 34
    • 78649741783 scopus 로고    scopus 로고
    • Gp130 at the nexus of inflammation, autoimmunity, and cancer
    • Silver JS, Hunter CA (2010) gp130 at the nexus of inflammation, autoimmunity, and cancer. J Leukoc Biol 88: 1145-56
    • (2010) J Leukoc Biol , vol.88 , pp. 1145-1156
    • Silver, J.S.1    Hunter, C.A.2
  • 35
    • 0027249367 scopus 로고
    • Human keratinocyte growth factor effects in a porcine model of epidermal wound healing
    • Staiano-Coico L, Krueger JG, Rubin JS et al. (1993) Human keratinocyte growth factor effects in a porcine model of epidermal wound healing. J Exp Med 178: 865-78
    • (1993) J Exp Med , vol.178 , pp. 865-878
    • Staiano-Coico, L.1    Krueger, J.G.2    Rubin, J.S.3
  • 36
    • 0033805794 scopus 로고    scopus 로고
    • Induction of the urokinase plasminogen activator system by oncostatin M promotes endothelial migration
    • Strand K, Murray J, Aziz S et al. (2000) Induction of the urokinase plasminogen activator system by oncostatin M promotes endothelial migration. J Cell Biochem 79: 239-48
    • (2000) J Cell Biochem , vol.79 , pp. 239-248
    • Strand, K.1    Murray, J.2    Aziz, S.3
  • 37
    • 78650496794 scopus 로고    scopus 로고
    • Fibroblasts from the growing margin of keloid scars produce higher levels of collagen i and III compared with intralesional and extralesional sites: Clinical implications for lesional site-directed therapy
    • Syed F, Ahmadi E, Iqbal SA et al. (2011) Fibroblasts from the growing margin of keloid scars produce higher levels of collagen I and III compared with intralesional and extralesional sites: clinical implications for lesional site-directed therapy. Br J Dermatol 164: 83-96
    • (2011) Br J Dermatol , vol.164 , pp. 83-96
    • Syed, F.1    Ahmadi, E.2    Iqbal, S.A.3
  • 38
    • 84856648815 scopus 로고    scopus 로고
    • Lipoprotein receptor-related protein 1 regulates collagen 1 expression, proteolysis, and migration in human pleural mesothelial cells
    • Tucker TA, Williams L, Koenig K et al. (2012) Lipoprotein receptor-related protein 1 regulates collagen 1 expression, proteolysis, and migration in human pleural mesothelial cells. Am J Respir Cell Mol Biol 46: 196-206
    • (2012) Am J Respir Cell Mol Biol , vol.46 , pp. 196-206
    • Tucker, T.A.1    Williams, L.2    Koenig, K.3
  • 39
    • 78049494644 scopus 로고    scopus 로고
    • Treatment of morphea or localized scleroderma: Review of the literature
    • Vilela FAS, Carneiro S, Ramos-e-Silva M (2010) Treatment of morphea or localized scleroderma: review of the literature. J Drugs Dermatol 9: 1213-9
    • (2010) J Drugs Dermatol , vol.9 , pp. 1213-1219
    • Vilela, F.A.S.1    Carneiro, S.2    Ramos-E-Silva, M.3
  • 40
    • 0038676258 scopus 로고    scopus 로고
    • Regulation of wound healing by growth factors and cytokines
    • Werner S, Grose R (2003) Regulation of wound healing by growth factors and cytokines. Physiol Rev 83: 835-70
    • (2003) Physiol Rev , vol.83 , pp. 835-870
    • Werner, S.1    Grose, R.2
  • 41
    • 34247192531 scopus 로고    scopus 로고
    • Keratinocyte-fibroblast interactions in wound healing
    • Werner S, Krieg T, Smola H (2007) Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol 127: 998-1008
    • (2007) J Invest Dermatol , vol.127 , pp. 998-1008
    • Werner, S.1    Krieg, T.2    Smola, H.3
  • 42
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • Wynn TA (2007) Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117: 524-9
    • (2007) J Clin Invest , vol.117 , pp. 524-529
    • Wynn, T.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.