Treatment of morphea or localized scleroderma: Review of the literature

Journal of Drugs in Dermatology

Volumn 9, Issue 10, 2010, Pages 1213-1219

  Santos Vilela, Fernanda Aguiar ^a   Carneiro, Sueli ^a   Ramos e Silva, Marcia ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIPOTRIOL; CALCITRIOL; COLCHICINE; CORTICOSTEROID; ETRETIN; GAMMA INTERFERON; IMIQUIMOD; MEPREDNISONE; METHOTREXATE; PENICILLAMINE; PENICILLIN G; PHENYTOIN; PREDNISONE; RETINOID DERIVATIVE; RETINOL DERIVATIVE; TACROLIMUS; TRIAMCINOLONE;

ABSENCE OF SIDE EFFECTS; ARTICLE; AUTOTRANSPLANTATION; CALCIUM METABOLISM; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTRACTURE; DISEASE COURSE; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG MECHANISM; HUMAN; KERATINOCYTE; LINEAR SCLERODERMA; LOW LEVEL LASER THERAPY; MORPHEA; PHOTODYNAMIC THERAPY; PHOTOTHERAPY; PHYSIOTHERAPY; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; SKIN SURGERY; SKIN TOXICITY; T LYMPHOCYTE; ULTRAVIOLET A RADIATION; UNSPECIFIED SIDE EFFECT; LOCALIZED SCLERODERMA; REVIEW;

ADRENAL CORTEX HORMONES; COLCHICINE; HUMANS; METHOTREXATE; PHOTOTHERAPY; SCLERODERMA, LOCALIZED; TACROLIMUS;

EID: 78049494644     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Carneiro SC, Earp APS, Brotas AM. [Scleroderma and sclerodermic states] Esclerodermia e estados esclerodermiformes. In: Ramose-Silva M, Castro MCR, ed. Fundamentos de Dermatologia. Rio de Janeiro: Atheneu. 2009:1259-1280.
2. rd ed. São Paulo: Artes Médicas, 2007;476-480.
3. Sapadin AN, Fleischmajer R. Treatment of Scleroderma. Arch Dermatol. 2002;138:99-105. (Pubitemid 34056240)
4. Sugiura K, Muro Y, Tomita Y. A case of a childhood linear scleroderma with limb asymmetry. Mod Rheumatol. 2004;14:254-256. (Pubitemid 39206673)
5. nd ed. New York: Mosby. 2008:1469-1483.
6. Seyger MMB, Van den Hoogen FHJ, De Boo T, et al. Low-dose methotrexate in the treatment of widespread morphea. J Am Acad Dermatol. 1998;39:220-225. (Pubitemid 28367333)
7. Uziel Y, Feldman BM, Krafchik BR, RS, et al. Methotrexate and corticosteroid therapy for pediatric localized scleroderma. J Pediatr. 2000;136:91-95. (Pubitemid 30468564)
8. Christen-Zaech S, Hakim MD, Afsar FS, Paller AS. Pediatric morphea (localized scleroderma): Review of 136 patients. J Am Acad Dermatol. 2008;59:385-396.
9. Kreuter A, Altmeyer P, Gambichler T. Treatment of localized scleroderma depends on the clinical subtype. Br J Dermatol. 2007;156:1363-1365.
10. Kroft EB, Creemers MC, Van den Hoogen FH, et al. Effectiveness, side-effects and period of remission after treatment with methotrexate in localized scleroderma and related sclerotic skin diseases: An inception cohort study. Br J Dermatol. 2009;160(5):1075-1082.
11. Kalaheb MB, Scharstein KK, LeRoy EC. Enhanced platelet adhesion to collagen in scleroderma. Effect of scleroderma plasma and scleroderma platelets. J Rheumatol. 1985;12(3):468-471. (Pubitemid 15004941)
12. Bibas R, Gaspar NK, Ramos-e-Silva M. Colchicine for dermatologic diseases. J Drugs Dermatol. 2005;4(2):196-204.
13. Alarcon-Segovia D, Ramos-Niembro F, Ibanez de Kasep G, Alcocer J, Tamayo RP. Long-term evaluation of colchicine in the treatment of scleroderma. J Rheumatol. 1979;6(6):705-712. (Pubitemid 10178207)
14. Sengezer M, Deveci M, Selmanpakoglu N. Repair of "coup de sabre," a linear form of scleroderma. Ann Plast Surg. 1996;37(4):428-432. (Pubitemid 26339861)
15. Lapiere J, Aasi S, Cook B, Montalvo A. Successful correction of depressed scars of the forehead secondary to trauma and morphea en coup do sabre by en bloc autologous dermal fat graft. Dermatol Surg. 2000;26(8):793-797. (Pubitemid 30620527)
16. Elst EF, Van Suijlekom-Smit LW, Oranje AP. Treatment of linear scleroderma with oral 1,25-dihydroxyvitamin D3 (calcitriol) in seven children. Pediatr Dermatol. 1999;16:53-58. (Pubitemid 29102635)
17. Cunningham BB, Landells ID, Langman C, et al. Topical calcipotriene for morphea/linear scleroderma. J Am Acad Dermatol. 1998;39(2 Pt 1):211-215. (Pubitemid 28367331)
18. Hulshof MM, Pavel S, Breedveld FC, et al. Oral calcitriol as a new therapeutic modality for generalized morphea. Arch Dermatol. 1994;130(10):1290-1293. (Pubitemid 24313289)
19. Bilen N, Apaydin R, Erçin C, et al. Coexistence of morphea and psoriasis responding to acitretin treatment. J Eur Acad Dermatol Venereol. 1999;13(2):113-117. (Pubitemid 29472350)
20. Man J, Dytoc MT. Use of imiquimod cream 5% in the treatment of localized morphea. J Cutan Med Surg. 2004;8(3):166-169. (Pubitemid 40063676)
21. Naiki Y, Maeda Y, Matsuo K, et al. Involvement of TGF-beta signal for peritoneal sclerosing in continuous ambulatory peritoneal dialysis. J Nephrol. 2003;16(1):95-102.
22. Ihn H. Pathogenesis of fibrosis: Role of TGF-beta and CTGF. Curr Opin Rheumatol. 2002;14(6):681-685. (Pubitemid 35191556)
23. Dytoc M, Ting PT, Man J, Sawyer D, Fiorillo L. First cases series on the use of imiquimod for morphoea. Br J Dermatol. 2005;153(4):815-820. (Pubitemid 41415912)
24. Campione E, Paternò EJ, Diluvio L, et AL. Localized morphea treated with imiquimod 5% and dermoscopic assessment of effectiveness. J Dermatolog Treat. 2009;20(1):10-13.
25. Hunzelmann N, Anders S, Fierlbeck G, et al. Double-blind, placebo-controlled study of intralesional interferon gamma for the treatment of localized scleroderma. J Am Acad Dermatol. 1997; 36(3 Pt 1):433-435. (Pubitemid 27131967)
26. Mancuso G, Berdondini RM. Topical tacrolimus in the treatment of localized scleroderma. Eur J Dermatol. 2003;13(6):590-592. (Pubitemid 38030805)
27. Stefanaki C, Stefanaki K, Kontochristopoulos G, et al. Topical tacrolimus 0.1% ointment in the treatment of localized scleroderma. An open label clinical and histological study. J Dermatol. 2008;35(11):712-718.
28. Kroft EB, Groeneveld TJ, Seyger MM, De Jong EM. Efficacy of topical tacrolimus 0.1% in active plaque morphea: Randomized, double-blind, emollient-controlled pilot study. Am J Clin Dermatol. 2009;10(3):181-187.
29. Wlaschek M, Briviba K, Stricklin P, et al. Singlet oxygen may mediate the ultraviolet-A - induced synthesis of interstitial collagenase. J Invest Dermatol. 1995;104:194-198.
30. Kerscher M, Volkenandt M, Gruss C, et al. Low-dose phototherapy for treatment of localized scleroderma. J Am Acad Dermatol. 1998;38(1):21-26. (Pubitemid 28100460)
31. Andres C, Kollmar A, Mempel M, et al. Successful ultraviolet A1 phototherapy in the treatment of localized scleroderma: A retrospective and prospective study. Br J Dermatol. 2009.
32. Sator PG, Radakovic S, Schulmeister K, et al. Medium-dose is more effective than low-dose ultraviolet A1 phototherapy for localized scleroderma as shown by 20-MHz ultrasound assessment. J Am Acad Dermatol. 2009;60(5):786-791.
33. Li SC, Liebling MS. The use of Doppler ultrasound to evaluate lesions of localized scleroderma. Curr Rheumatol Rep. 2009;11(3):205-211.
34. Kerscher M, Meurer M, Sander C, et al. PUVA bath photochemotherapy for localized scleroderma. Evaluation of 17 consecutive patients. Arch Dermatol. 1996;132(11):1280-1282. (Pubitemid 26386612)
35. Kreuter A, Hyun J, Stücker M, et al. A randomized controlled studyof low-dose UVA1, medium-dose UVA1, and narrowband UVB phototherapy in the treatment of localized scleroderma. J Am Acad Dermatol. 2006;54(3):440-447. (Pubitemid 43243447)
36. Babilas P, Landthaler M, Szeimies RM. Photodynamic therapy in dermatology. Eur J Dermatol. 2006;16(4) 340-348. (Pubitemid 44328972)
37. Babilas P, Karrer S, Sidoroff A, et al. Photodynamic therapy in dermatology - An update. Photodermatol Photoimmunol Photomed. 2005;21(3):142-149. (Pubitemid 40778615)
38. Karrer S, Abels C, Landthaler M, Szeimies RM. Topical photodynamic therapy for localized scleroderma. Acta Derm Venereol. 2000;80(1):26-27. (Pubitemid 30110844)
39. Eisen D, Alster TS. Use of a 585 nm pulsed dye laser for the treatment of morphea. Dermatol Surg. 2002;28(7):615-616. (Pubitemid 34816047)
40. Roh MR, Jung JY, Chung KY. Autologous fat transplantation for depressed linear scleroderma-induced facial atrophic scars. Dermatol Surg. 2008;34(12):1659-1665.