Multi-faceted characterization of pharmaceutical powders to discern the influence of surface modification

Powder Technology

Volumn 236, Issue , 2013, Pages 63-74

  Ghoroi, Chinmay ^a,b   Gurumurthy, Lakxmi ^a   McDaniel, D J ^a   Jallo, Laila J ^a   Davé, Rajesh N ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^b INDIAN INSTITUTE OF TECHNOLOGY GANDHINAGAR   (India)

Author keywords

Packing; Pharmaceutical powder; Phase map; Powder characterization; Powder flow; Surface modification

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; ANGLE OF REPOSE; BULK DENSITY; COHESIVITY; DIFFERENT PARTICLE SIZES; DRY COATING; FLOW FUNCTION; FLOW INDICES; FLOW REGIMES; FLOW REGIONS; FREE FLOW; MEASURED PROPERTIES; PHARMACEUTICAL POWDER; PHASE MAPS; POWDER CHARACTERIZATION; POWDER FLOW; PROPERTY IMPROVEMENT; RANK ORDER; SURFACE-MODIFIED;

CHARACTERIZATION; ORGANIC ACIDS; PACKING; SURFACE TREATMENT;

POWDERS;

ASCORBIC ACID; EXCIPIENT; IBUPROFEN; PARACETAMOL;

AERATIBILITY; ANALYTIC METHOD; ANGLE OF REPOSE; ARTICLE; BULK DENSITY; CARR INDEX; CHEMICAL MODIFICATION; COHESIVITY; DRUG COATING; DRUG PACKAGING; DRY COATING; FLOW FUNCTION COEFFICIENT; FLOW INDEX; HOUSNER RATIO; PARTICLE SIZE; PHARMACOLOGICAL PARAMETERS; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; POWDER; POWDER FLOW; SURFACE PROPERTY;

EID: 84873740107     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.05.039     Document Type: Article

References (53)

1. Jivraj I.I., Martini M.L., Thomson C. An overview of the different excipients useful for the direct compression of tablets. Pharmaceutical Science & Technology Today 2000, 3:58-63.
2. Guerin E., Tchoreloff P., Leclerc B., Tanguy D., Deleuil M., Couarraze G. Rheological characterization of pharmaceutical powders using tap testing, shear cell and mercury porosimeter. International Journal of Pharmaceutics 1999, 189:91-103.
3. Tan S., Newton J. Powder flowability as an indication of capsule filling performance. International Journal of Pharmaceutics 1990, 61:145-155.
4. Thalberg K., Lindholm D., Axelsson A. Comparison of different flowability tests for powders for inhalation. Powder Technology 2004, 146:206-213.
5. Li Q., Rudolph V., Weigl B., Earl A. Interparticle van der Waals force in powder flowability and compactibility. International Journal of Pharmaceutics 2004, 280:77-93.
6. Molerus O., Nywlt M. The influence of the fine particle content of the flow behaviour of bulk materials. Powder Technology 1984, 37:145-154.
7. Vasilenko A., Glasser B.J., Muzzio F.J. Shear and flow behavior of pharmaceutical blends-method comparison study. Powder Technology 2011, 208:628-636.
8. Deleuil M., Chulia D., Pourcelot Y. Particle and powder dynamics. Handbook of Powder Technology and Pharmaceutical Processes 1994, vol. 9:115-163. Elsevier Science B.V. M. Deleuil, D. Chulia, Y. Pourcelot (Eds.).
9. Prescott J.J., Barnum R.A. On powder flowability. Pharmaceutical Technology 2000, 24:60-84.
10. Krantz M., Zhang H., Zhu J. Characterization of powder flow: static and dynamic testing. Powder Technology 2009, 194:239-245.
11. Ridgway K., Scotton J.B. Aspects of pharmaceutical engineering. The Pharmaceutical Journal 1972, 208:574-576.
12. Castellanos A., Valverde J.M., P'erez A.T., Ramos A., Watson P.K. Flow regimes in fine cohesive powders. Physical Review Letters 1999, 82:1156-1159.
13. Rios M. Developments in powder flow testing. Pharmaceutical Technology 2006, 57:287-294.
14. Schwedes J. Consolidation and flow of cohesive bulk solids. Chemical Engineering Science 2002, 57:287-294.
15. Hiestand E.N. Tablet bond. I. A theoretical model. International Journal of Pharmaceutics 1991, 67:217-229.
16. Hiestand E.N., Smith D.P. Tablet bond. II. Experimental check of model. International Journal of Pharmaceutics 1991, 67:231-246.
17. Carr R.L. Classifying flow properties of solids. Chemical Engineer 1965, 72:69-72.
18. Hausner H.H. Friction conditions in a mass of metal powder. International Journal of Powder Metallurgy 1967, 3:7-13.
19. Lee Y.S.L., Poynter R., Podczeck F., Newton J.M. Development of a dual approach to assess powder flow from avalanching behavior. AAPS PharmSciTech 2000, 1(3):44-52.
20. Soh J.I., Liew C.V., Heng P. New indices to characterize powder flow based on their avalanching behavior. Pharmaceutical Development and Technology 2006, 11:13-21.
21. Liu L., Marziano I., Bentham A., Litster J., White E., Howes T. Effect of particle properties on the flowability of ibuprofen powders. International Journal of Pharmaceutics 2008, 362:109-117.
22. Seppälä K., Heinämäki J., Hatara J., Seppälä L., Yliruusi J. Development of a new method to get a reliable powder flow characteristics using only 1 to 2g of powder. AAPS PharmSciTech March 2010, 11(1). (# 2010). 10.1208/s12249-010-9397-9.
23. Mullarney M.P., Beach L.E., Dav'e R.N., Langdon B., Polizzi M., Blackwood D. Applying dry powder coatings to pharmaceutical powders using a comil for improving powder flow and bulk density. Powder Technology 2011, 212:397-402.
24. Jallo Laila, Ghoroi C., Gurumurthy L., Patel U., Dav'e R.N. Improvement in flowability and bulk density of pharmaceutical powders using surface modification. International Journal of Pharmaceutics 2011, 28:213-225.
25. Yang J., Sliva A., Banerjee A., Dave R.N., Pfeffer R. Dry particle coating for improving the flowability of cohesive powders. Powder Technology 2005, 158:21-33.
26. Ramlakhan M., Wu C.Y., Watano S., Dave R.N., Pfeffer R. Dry particle coating using magnetically assisted impaction coating: modification of surface properties and optimization of system and operating parameters. Powder Technology 2000, 112:137-148.
27. Pfeffer R., Dave R.N., Wei D., Ramlakhan M. Synthesis of engineered particulates with tailored properties using dry particle coating. Powder Technology 2001, 117:40-67.
28. Chen Y., Quintanilla M.A., Yang J.V.J.M., Dave R.N. Pull-off force of coated fine powders under small consolidation. Physical Review E 2009, 79. [041305-1 - 041305-14].
29. Chen Y., Jallo L., Quintanilla M.A., Dave R.N. Characterization of particle and bulk level cohesion reduction of surface modified fine aluminum powders. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2010, 361:66-80.
30. Ghoroi C., Jallo J.L., Gurumurthy L., Patel U., To D., Beach L., Dav'e R.N. Improvement in flowability and bulk density of pharmaceutical powders thorough surface modification. AIChE Annual Meeting, Salt Lake City, UT 2010.
31. Hancock Bruno C., Colvin Joshua T., Mullarney Matthew P., Zinchuk Andrey V. The relative densities of pharmaceutical powders, blends, dry granulations, and immediate release tablets. Pharmaceutical Technology April 2003, 64-80.
32. Lavoie F., Cartilier L., Thibert R. New methods characterizing avalanche behavior to determine powder flow. Pharmaceutical Research 2002, 19:887-893.
33. Geldart D., Abdullah E., Verlinden A. Characterisation of dry powders. Powder Technology 2009, 190:70-74.
34. Rambali B., Baert L., Massart D.L. Using experimental design to optimize the process parameters in fluidized bed granulation on a semi-full scale. International Journal of Pharmaceutics 2001, 220:149-160.
35. Santomaso A., Lazzaro P., Canu P. Powder flowability and density ratios: the impact of granules packing. Chemical Engineering Science 2003, 58:2857-2874.
36. Abdullah E.C., Geldart D. The use of bulk density measurements as flowability indicators. Powder Technology 1999, 102:151-165.
37. Castellanos A. The relationship between attractive interparticle forces and bulk behaviour in dry and uncharged fine powders. Advances in Physics 2005, 54:263-376.
38. Harnby N., Hawkins A., Vandame D. The use of bulk density determination as a means of typifying the flow characteristics of loosely compacted powders under conditions of variable relative humidity. Chemical Engineering Science 1987, 42:879-888.
39. Dutta A., Dullea L.V. A comparative evaluation of negatively and positively charged submicron particles as flow conditioners for a cohesive powder. AIChE Symposium Series 1990, 86:26-40.
40. Geldart D. Types of gas fluidization. Powder Technology 1973, 7:285-292.
41. Geldart D., Wong D.A.C.Y. Fluidization of powders showing degrees of cohesiveness-I. Bed expansion. Chemical Engineering Science 1984, 39:1481-1488.
42. Zou R.P., Yu A.B. Evaluation of the packing characteristics of mono-sized non-spherical particles. Powder Technology 1996, 88:71-79.
43. Freeman R.E. Predicting flowability and characterizing powders. Pharmaceutical Technology Europe 2004, 16:41-43.
44. Freeman R. Measuring the flow properties of consolidated, conditioned and aerated powders-a comparative study using a powder rheometer and a rotational shearcell. Powder Technology 2007, 174:25-33.
45. Schulze D. Powders and Bulk Solids 2008, Springer.
46. Freeman T., Price R. Dynamic powder characterization for DPI formulation. Drug Delivery Technology 2009, 9:50-55.
47. Dav'e R.N., Ghoroi C., Han X., D.To, Jallo L., Gurumurthy L. Dispersion of ultrafine powders through surface modification or rapid expansion. Nisshin Engineering Particle Technology International Seminar (NEPTIS), Sendai, Japan 2010.
48. Han Xi, Ghoroi C., D.To, Chen Y., Dav'e R.N. Simultaneous micronization and surface modification for improvement of flow and dissolution of drug particles. International Journal of Pharmaceutics 2011, 415:185-195.
49. C.Ghoroi, X.Han, L. Jallo, L. Gurumurthy, R.N. Dav'e, Dispersion of fine and ultrafine powders through surface modification and rapid expansion, Chemical Engineering Science, (In Press, Available online), http://dx.doi.org/10.1016/j.ces.2012.02.038.
50. Wong A.C.-Y. Characterisation of the flowability of glass beads by bulk densities ratio. Chemical Engineering Science 2000, 55:3855-3859.
51. Yu A.B., Bridgwater J., Burbidge A. On the modelling of the packing of fine particles. Powder Technology 1997, 92:185-194.
52. Podczeck F. Particle-particle adhesion in pharmaceutical powder handling 1998, London, Imperial College Press, London.
53. Geldart D., Abdullah E.C., Verlinden A. Characterization of dry powders. Powder Technology 2009, 190(1-2):70-74.