Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA

Cell Research

Volumn 23, Issue 2, 2013, Pages 213-224

  Wang, Zixi ^a   Wu, Yaling ^b   Li, Lanfen ^a   Su, Xiao Dong ^a  

^a PEKING UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

Author keywords

BMAL1; circadian; CLOCK; crystal structure; non canonical E box; phosphorylation

Indexed keywords

DNA; HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK;

ARTICLE; BINDING SITE; CHEMICAL PHENOMENA; CHEMISTRY; E BOX ELEMENT; GENETICS; HUMAN; HYDROGEN BOND; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PROTEIN BINDING;

ARNTL TRANSCRIPTION FACTORS; BASE SEQUENCE; BINDING SITES; CLOCK PROTEINS; DNA; E-BOX ELEMENTS; HELIX-LOOP-HELIX MOTIFS; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MUTATION; PHOSPHORYLATION; PROTEIN BINDING;

MAMMALIA;

EID: 84873738229     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2012.170     Document Type: Article

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