Formulation design space analysis for drug release from swelling polymer tablets

Powder Technology

Volumn 236, Issue , 2013, Pages 179-187

  Kimber, James A ^a   Kazarian, Sergei G ^a   Štěpánek, František ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

Author keywords

DEM; Drug release; FT IR spectroscopic imaging; Mathematical modelling; Tablet dissolution

Indexed keywords

ATTENUATED TOTAL REFLECTION FOURIER TRANSFORM INFRARED; BURST RELEASE; CONCENTRATION PROFILES; DEM; DISSOLUTION MODEL; DRUG DISTRIBUTION; DRUG LOADING; DRUG RELEASE; FORMULATION DESIGN; FT-IR SPECTROSCOPIC IMAGING; FTIR; GEL LAYERS; KEY PARAMETERS; MASS FRACTION; PARAMETRIC STUDY; POLYMER CONCENTRATIONS; POLYMER NETWORKS; POLYMER SWELLING; PURE COMPONENTS; RELEASE TIME; SPECTROSCOPIC IMAGING; SWELLING POLYMERS; SWELLING RATIO; UNSTRUCTURED GRID; WATER INGRESS;

AMIDES; DIFFUSION; DRUG DOSAGE; FINITE DIFFERENCE METHOD; LOADING; MATHEMATICAL MODELS; SWELLING;

POLYMERS;

NICOTINAMIDE; POLYMER;

ARTICLE; CONCENTRATION (PARAMETERS); DIFFUSION COEFFICIENT; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG RELEASE; INFRARED SPECTROSCOPY; PARAMETRIC TEST; SIMULATION; TABLET FORMULATION; THICKNESS; ULTRAVIOLET SPECTROSCOPY;

EID: 84873737001     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.02.027     Document Type: Article

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