Distribution and accessibility of binder in wet granules

Powder Technology

Volumn 189, Issue 2, 2009, Pages 376-384

  Stepanek F ^a   Rajniak, P ^b   Mancinelli, C ^b   Chern, R T ^b   Ramachandran, R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Agglomeration kernel; Computer simulation; Microstructure; Particle shape; Wet granulation

Indexed keywords

AGGLOMERATION KERNEL; DIGITAL IMAGE ANALYSIS (DIA); EQUILIBRIUM DISTRIBUTIONS; GRANULATION KINETICS; PARTICLE MORPHOLOGIES; PARTICLE SHAPE; PARTICLE SURFACES; PHARMACEUTICAL EXCIPIENTS; PORE SPACES; PRIMARY PARTICLES; RANDOM PACKINGS; SHAPE FACTORS; SPATIAL DISTRIBUTIONS; SURFACE COVERAGES; VOLUME-OF-FLUID (VOF); WET GRANULATION;

AGGLOMERATION; BINDERS; CALCIUM; CALCIUM PHOSPHATE; CELLULOSE DERIVATIVES; COMPUTER SIMULATION; IMAGE ANALYSIS; MICROSTRUCTURE; POLYDISPERSITY; SIZE DISTRIBUTION; SUGARS; SURFACE ROUGHNESS; THREE DIMENSIONAL;

GRANULATION;

CALCIUM PHOSPHATE; EXCIPIENT; LACTOSE; MANNITOL; MICROCRYSTALLINE CELLULOSE;

ARTICLE; COMPUTER; CONTROLLED STUDY; IMAGE ANALYSIS; KINETICS; LIQUID; PARTICLE SIZE; SIMULATION; SOLID; SPATIAL DISCRIMINATION; SURFACE PROPERTY; THREE DIMENSIONAL IMAGING;

AGGLOMERATION; BINDERS; CALCIUM PHOSPHATE; CELLULOSE DERIVATIVES; GRANULATION; GRANULES; IMAGE ANALYSIS; LIQUIDS; MICROSTRUCTURE; MOLECULAR WEIGHT DISTRIBUTION; ROUGHNESS; SIMULATION; SUGARS;

EID: 58749092020     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2008.04.015     Document Type: Article

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