Modelling of pharmaceutical tablet swelling and dissolution using discrete element method

Chemical Engineering Science

Volumn 69, Issue 1, 2012, Pages 394-403

  Kimber, James A ^a   Kazarian, Sergei G ^a   Štěpánek, František ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

Author keywords

Diffusion; Dissolution; FT IR spectroscopic imaging; Mathematical modelling; Pharmaceuticals; Polymer swelling

Indexed keywords

ATR FTIR; CHEMICAL IMAGES; CONCENTRATION PROFILES; CONCENTRATION-DEPENDENT; CONCENTRATION-DEPENDENT DIFFUSION; DEM SIMULATION; DISSOLUTION RATES; FT-IR SPECTROSCOPIC IMAGING; MATHEMATICAL MODELLING; METHYLCELLULOSE; NUMERICAL SOLUTION; PARAMETRIC STUDY; PHARMACEUTICAL TABLETS; PHYSICAL PARAMETERS; POLYMER SWELLING; RADIAL EXPANSIONS; SPECTROSCOPIC IMAGING; WATER DIFFUSION COEFFICIENTS;

CONCENTRATION (PROCESS); DIFFUSION; DIFFUSION IN LIQUIDS; DRUG PRODUCTS; NUMERICAL METHODS; POLYMERS; RATE CONSTANTS; SWELLING;

DISSOLUTION;

EID: 83955163648     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2011.10.066     Document Type: Article

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