Self-administration of cocaine induces dopamine-independent self-administration of sigma agonists

Neuropsychopharmacology

Volumn 38, Issue 4, 2013, Pages 605-615

  Hiranita, Takato ^a   Mereu, Maddalena ^a   Soto, Paul L ^b   Tanda, Gianluigi ^a   Katz, Jonathan L ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

receptor; cocaine; dopamine; drug reinforcement history; drug self administration; reinforcement mechanisms

Indexed keywords

1 PHENYLCYCLOHEXANECARBOXYLIC ACID 2 MORPHOLINOETHYL ESTER; BD 1063; COCAINE; DOPAMINE RECEPTOR BLOCKING AGENT; OPIATE AGONIST; OPIATE ANTAGONIST; PENTAZOCINE; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DRUG SELF ADMINISTRATION; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT;

ANALGESICS, OPIOID; ANIMALS; COCAINE; DOPAMINE; DOPAMINE ANTAGONISTS; MALE; PENTAZOCINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SIGMA; SELF ADMINISTRATION;

EID: 84873735908     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.224     Document Type: Article

References (53)

1. Aydar E, Palmer CP, Klyachko VA, Jackson MB (2002). The sigma receptor as a ligand-regulated auxiliary potassium channel subunit. Neuron 34: 399-410.
2. Barrett AC, Miller JR, Dohrmann JM, Caine SB (2004). Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats. Neuropharmacology 47(Suppl 1): 256-273.
3. Barrett JE (1977). Behavioral history as a determinant of the effects of d-amphetamine on punished behavior. Science 198: 67-69.
4. Collins GT, Woods JH (2007). Drug and reinforcement history as determinants of the response-maintaining effects of quinpirole in the rat. J Pharmacol Exp Ther 323: 599-605.
5. Collins GT, Woods JH (2009). Influence of conditioned reinforcement on the response-maintaining effects of quinpirole in rats. Behav Pharmacol 20: 492-504.
6. Cormaci G, Mori T, Hayashi T, Su TP (2007). Protein kinase A activation down-regulates, whereas extracellular signal-regulated kinase activation up-regulates sigma-1 receptors in B-104 cells: implication for neuroplasticity. J Pharmacol Exp Ther 320: 202-210.
7. Fontanilla D, Johannessen M, Hajipour AR, Cozzi NV, Jackson MB, Ruoho AE (2009). The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator. Science 323: 934-937.
8. Garcés-Ram?́rez L, Green J, Hiranita T, Kopajtic T, Mereu M, Thomas A et al 2011) Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis in rats. Biol Psychiatry 69,208-217.
9. Glowa JR, Barrett JE (1983). Drug history modifies the behavioral effects of pentobarbital. Science 220: 333-335.
10. Gorelick DA, Gardner EL, Xi ZX (2004). Agents in development for the management of cocaine abuse. Drugs 64: 1547-1573.
11. Gudelsky GA (1995). Effects of sigma receptor ligands on the extracellular concentration of dopamine in the striatum and prefrontal cortex of the rat. Eur J Pharmacol 286: 223-228.
12. Hayashi T, Justinova Z, Hayashi E, Cormaci G, Mori T, Tsai SY et al (2010). Regulation of sigma-1 receptors and endoplasmic reticulum chaperones in the brain of methamphetamine selfadministering rats. J Pharmacol Exp Ther 332: 1054-1063.
13. Hayashi T, Su TP (2007). Sigma-1 receptor chaperones at the ERmitochondrion interface regulate Ca(2\+) signaling and cell survival. Cell 131: 596-610.
14. Heikkila RE, Orlansky H, Cohen G (1975). Studies on the distinction between uptake inhibition and release of [3H]dopamine in rat brain tissue slices. Biochem Pharmacol 24: 847-852.
15. Hemby SE, Smith JE, Dworkin SI (1996). The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats. J Pharmacol Exp Ther 277: 1247-1258.
16. Hill RT (1970). Facilitation of conditioned reinforcement as a mechanism of psychomotor stimulation. In: Costa E, Garattini S (eds). Amphetamines and Related Compounds, Raven Press: New York, pp 781-795.
17. Hiranita T, Soto P, Tanda G, Katz J 2011a). Lack of cocaine-like discriminative-stimulus effects of s receptor agonists in rats. Behav Pharmacol 22: 525-530.
18. Hiranita T, Soto PL, Kohut SJ, Kopajtic T, Cao J, Newman AH et al 2011b). Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and {s} receptors. J Pharmacol Exp Ther 339: 662-677.
19. Hiranita T, Soto PL, Newman AH, Katz JL (2009). Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors. J Pharmacol Exp Ther 329: 677-686.
20. Hiranita T, Soto PL, Tanda G, Katz JL (2010). Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine. J Pharmacol Exp Ther 332: 515-524.
21. Katz JL, Su TP, Hiranita T, Hayashi T, Tanda G, Kopajtic T et al 2011). A role for sigma receptors in stimulant self administration and addiction. Pharmaceuticals 4: 880-914.
22. Li SM, Campbell BL, Katz JL (2006). Interactions of cocaine with dopamine uptake inhibitors or dopamine releasers in rats discriminating cocaine. J Pharmacol Exp Ther 317: 1088-1096.
23. Liu Y, Chen GD, Lerner MR, Brackett DJ, Matsumoto RR (2005). Cocaine up-regulates Fra-2 and sigma-1 receptor gene and protein expression in brain regions involved in addiction and reward. J Pharmacol Exp Ther 314: 770-779.
24. Liu Y, Matsumoto RR (2008). Alterations in fos-related antigen 2 and sigma1 receptor gene and protein expression are associated with the development of cocaine-induced behavioral sensitization: time course and regional distribution studies. J Pharmacol Exp Ther 327: 187-195.
25. Maj J, Rogoz Z, Skuza G (1996). Some behavioral effects of 1,3-dio-tolylguanidine, opipramol and sertraline, the sigma site ligands. Polish J Pharmacol 48: 379-395.
26. Martin-Fardon R, Maurice T, Aujla H, Bowen WD, Weiss F (2007). Differential effects of sigma1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward. Neuropsychopharmacology 32: 1967-1973.
27. Matsumoto RR (2009). Targeting sigma receptors: novel medication development for drug abuse and addiction. Expert Rev Clin Pharmacol 2: 351-358.
28. Matsumoto RR, McCracken KA, Friedman MJ, Pouw B, De Costa BR, Bowen WD (2001). Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice. Eur J Pharmacol 419: 163-174.
29. Maurice T, Su TP (2009). The pharmacology of sigma-1 receptors. Pharmacol Ther 124: 195-206.
30. McCracken KA, Bowen WD, de Costa BR, Matsumoto RR (1999). Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity. Eur J Pharmacol 370: 225-232.
31. Meunier J, Demeilliers B, Celerier A, Maurice T (2006). Compensatory effect by sigma1 (s1) receptor stimulation during alcohol withdrawal in mice performing an object recognition task. Behav Brain Res 166: 166-176.
32. Navarro G, Moreno E, Aymerich M, Marcellino D, McCormick PJ, Mallol J et al (2010). Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine. Proc Nat Acad Sci USA 107: 18676-18681.
33. Nuwayhid SJ, Werling LL (2003). Sigma1 receptor agonistmediated regulation of N-methyl-D-aspartate-stimulated [3H]dopamine release is dependent upon protein kinase C. J Pharmacol Exp Ther 304: 364-369.
34. O0Connell AW, Earley B, Leonard BE (1996). The sigma ligand JO 1784 prevents trimethyltin-induced behavioural and sigma-receptor dysfunction in the rat. Pharmacol Toxicol 78: 296-302.
35. Patrick SL, Walker JM, Perkel JM, Lockwood M, Patrick RL (1993). Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligands. Eur J Pharmacol 231: 243-249.
36. Paxinos G, Watson C (1998). The Rat Brain in Stereotaxic Coordinates. Sidney, Australia: Academic Press.
37. Pontieri FE, Tanda G, Di Chiara G (1995). Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proc Nat Acad Sci USA 92: 12304-12308.
38. Pontieri FE, Tanda G, Orzi F, Di Chiara G (1996). Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 382: 255-257.
39. Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987). Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237: 1219-1223.
40. Romieu P, Martin-Fardon R, Maurice T (2000). Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 11: 2885-2888.
41. Romieu P, Phan VL, Martin-Fardon R, Maurice T (2002). Involvement of the sigma(1) receptor in cocaine-induced conditioned place preference: possible dependence on dopamine uptake blockade. Neuropsychopharmacology 26: 444-455.
42. Sharkey J, Glen KA, Wolfe S, Kuhar MJ (1988). Cocaine binding at sigma receptors. Eur J Pharmacol 149: 171-174.
43. Stefanski R, Justinova Z, Hayashi T, Takebayashi M, Goldberg SR, Su TP (2004). Sigma1 receptor upregulation after chronic methamphetamine self-administration in rats: a study with yoked controls. Psychopharmacology 175: 68-75.
44. Stefanski R, Ladenheim B, Lee SH, Cadet JL, Goldberg SR (1999). Neuroadaptations in the dopaminergic system after active selfadministration but not after passive administration of methamphetamine. Eur J Pharmacol 371: 123-135.
45. Tanda G, Ebbs A, Newman AH, Katz JL (2005). Effects of 40-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine. J Pharmacol Exp Ther 313: 613-620.
46. Tanda G, Kopajtic TA, Katz JL (2008). Cocaine-like neurochemical effects of antihistaminic medications. J Neurochem 106: 147-157.
47. Tanda G, Pontieri FE, Di Chiara G (1997). Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism. Science 276: 2048-2050.
48. van Rossum JM, Hurkmans JAThM (1964). Mechanism of action of psychomotor stimulant drugs: significance of dopamine in locomotor stimulant action. Int J Neuropharmacol 3: 227-239.
49. Vocci FJ, Acri J, Elkashef A (2005a). Medication development for addictive disorders: the state of the science. Am J Psychiatry 162: 1432-1440.
50. Vocci FJ, Elkashef A (2005b). Pharmacotherapy and other treatments for cocaine abuse and dependence. Curr Opin Psychiatry 18: 265-270.
51. Witkin JM, Nichols DE, Terry P, Katz JL (1991). Behavioral effects of selective dopaminergic compounds in rats discriminating cocaine injections. J Pharmacol Exp Ther 257: 706-713.
52. Young AM, Woods JH (1981). Maintenance of behavior by ketamine and related compounds in rhesus monkeys with different selfadministration histories. J Pharmacol Exp Ther 218: 720-727.
53. Zhang D, Zhang L, Tang Y, Zhang Q, Lou D, Sharp FR et al (2005). Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology 30: 1443-1454.