Multi-component population balance modeling of granulation with continuous addition of binder

Powder Technology

Volumn 236, Issue , 2013, Pages 211-220

  Marshall, Carl L ^a   Rajniak, Pavol ^b   Matsoukas, Themis ^a  

^a The Pennsylvania State University   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Granulation; Monte Carlo; Multi component; Population balance

Indexed keywords

BINDER CONTENT; BINDER VISCOSITY; CONTINUOUS PROCESS; FLUID BED GRANULATION; GRANULE SIZE; MONTE CARLO; MONTE CARLO ALGORITHMS; MULTI-DIMENSIONAL POPULATION BALANCE MODELS; MULTICOMPONENTS; PARTICLE MORPHOLOGIES; PHARMACEUTICAL INDUSTRY; POPULATION BALANCE MODELING; POPULATION BALANCES;

BINDERS; GRANULATION; MONTE CARLO METHODS; MORPHOLOGY;

PARTICLES (PARTICULATE MATTER);

CALCIUM PHOSPHATE DIBASIC; MANNITOL; MICROCRYSTALLINE CELLULOSE;

ARTICLE; COMPUTER SIMULATION; DRUG GRANULATION; DRUG GRANULE; MONTE CARLO METHOD; MORPHOLOGY; MULTI COMPONENT POPULATION BALANCE MODEL; PARTICLE SIZE; PHYSICAL MODEL; POROSITY; VISCOSITY; WETTABILITY;

EID: 84873731672     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.01.027     Document Type: Article

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