Vitamin D and Parathyroid Hormone in Outpatients With Noncholestatic Chronic Liver Disease

Clinical Gastroenterology and Hepatology

Volumn 5, Issue 4, 2007, Pages 513-520

  Fisher, Leon ^a   Fisher, Alexander ^a  

^a CANBERRA HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; CREATININE; MAGNESIUM; PARATHYROID HORMONE; PHOSPHATE; SERUM ALBUMIN; VITAMIN D;

ADULT; ALCOHOLISM; ALKALINE PHOSPHATASE BLOOD LEVEL; ANEMIA; ARTICLE; AUTOIMMUNE HEPATITIS; BLOOD CLOTTING DISORDER; CALCIUM BLOOD LEVEL; CHEMICAL PARAMETERS; CHRONIC LIVER DISEASE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEMOGRAPHY; DISEASE SEVERITY; FEMALE; HEMOCHROMATOSIS; HEPATITIS B; HEPATITIS C; HORMONE BLOOD LEVEL; HUMAN; HYPERBILIRUBINEMIA; HYPERPARATHYROIDISM; HYPOALBUMINEMIA; INTERNATIONAL NORMALIZED RATIO; LIVER CIRRHOSIS; LIVER FUNCTION; LIVER FUNCTION TEST; MAGNESIUM BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; PHOSPHATE BLOOD LEVEL; PREVALENCE; THROMBOCYTOPENIA; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY;

ADULT; AGE FACTORS; AGED; BIOLOGICAL MARKERS; CHOLESTASIS; CHRONIC DISEASE; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; HUMANS; LINEAR MODELS; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OUTPATIENTS; PARATHYROID HORMONE; PROBABILITY; PROGNOSIS; REFERENCE VALUES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SEX FACTORS; VITAMIN D;

EID: 34147144615     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2006.10.015     Document Type: Article

References (59)

1. DeLuca H.F. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 80 (2004) S1689-S1696
2. Dusso A.S., Brown A.J., and Slatopolsky E. Vitamin D. Am J Physiol 289 (2005) F8-F28
3. Nagpal S., Na S., and Rathnachalam R. Noncalcemic actions of vitamin D receptor ligands. Endocr Rev 26 (2005) 662-687
4. Canaff L., Petit J.L., Kisiel M., et al. Extracellular calcium-sensing receptor is expressed in rat hepatocytes. Coupling to intracellular calcium mobilization and stimulation of bile flow. J Biol Chem 276 (2001) 4070-4079
5. Peterlik M., and Cross H.S. Vitamin D and calcium deficits predispose for multiple chronic diseases. Eur J Clin Invest 35 (2005) 290-304
6. Gascon-Barre M., Demers C., Mirshahi A., et al. The normal liver harbors the vitamin D nuclear receptor in nonparenchymal and biliary epithelial cells. Hepatology 37 (2003) 1034-1042
7. Funk J.L., Moser A.H., Grunfeld C., et al. Parathyroid hormone-related protein is induced in the adult liver during endotoxemia and stimulates the hepatic acute phase response. Endocrinology 138 (1997) 2665-2673
8. Mitnick M.A., Grey A., Masiukiewicz U., et al. Parathyroid hormone induces hepatic production of bioactive interleukin-6 and its soluble receptor. Am J Physiol 280 (2001) E405-E412
9. Hay J.E., and Guichelaar M.M. Evaluation and management of osteoporosis in liver disease. Clin Liver Dis 9 (2005) 747-766 viii
10. Leslie W.D., Bernstein C.N., and Leboff M.S. AGA technical review on osteoporosis in hepatic disorders. Gastroenterology 125 (2003) 941-966
11. Gallego-Rojo F.J., Gonzalez-Calvin J.L., Munoz-Torres M., et al. Bone mineral density, serum insulin-like growth factor I, and bone turnover markers in viral cirrhosis. Hepatology 28 (1998) 695-699
12. Hepner G.W., Roginsky M., and Moo H.F. Abnormal vitamin D metabolism in patients with cirrhosis. Am J Dig Dis 21 (1976) 527-532
13. Tsuneoka K., Tameda Y., Takase K., et al. Osteodystrophy in patients with chronic hepatitis and liver cirrhosis. J Gastroenterol 31 (1996) 669-678
14. Shiomi S., Masaki K., Habu D., et al. Calcitriol for bone disease in patients with cirrhosis of the liver. J Gastroenterol Hepatol 14 (1999) 547-552
15. Crosbie O.M., Freaney R., McKenna M.J., et al. Bone density, vitamin D status, and disordered bone remodeling in end-stage chronic liver disease. Calcif Tissue Int 64 (1999) 295-300
16. Crawford B.A., Kam C., Donaghy A.J., et al. The heterogeneity of bone disease in cirrhosis: a multivariate analysis. Osteoporos Int 14 (2003) 987-994
17. Ormarsdottir S., Ljunggren O., Mallmin H., et al. Increased rate of bone loss at the femoral neck in patients with chronic liver disease. Eur J Gastroenterol Hepatol 14 (2002) 43-48
18. Diamond T.H., Stiel D., Lunzer M., et al. Hepatic osteodystrophy. Static and dynamic bone histomorphometry and serum bone Gla-protein in 80 patients with chronic liver disease. Gastroenterology 96 (1989) 213-221
19. van der Merwe S.W., Attfield D., Fevery J., et al. Hepatic osteodystrophy: the influence of liver disease and portal hypertension on cytokine activation. Med Hypotheses 54 (2000) 842-845
20. Floreani A., Zappala F., Fries W., et al. A 3-year pilot study with 1,25-dihydroxyvitamin D, calcium, and calcitonin for severe osteodystrophy in primary biliary cirrhosis. J Clin Gastroenterol 24 (1997) 239-244
21. Floreani A., Mega A., Camozzi V., et al. Is osteoporosis a peculiar association with primary biliary cirrhosis?. World J Gastroenterol 11 (2005) 5347-5350
22. Duarte M.P., Farias M.L., Coelho H.S., et al. Calcium-parathyroid hormone-vitamin D axis and metabolic bone disease in chronic viral liver disease. J Gastroenterol Hepatol 16 (2001) 1022-1027
23. Compston J.E., Greer S., Skingle S.J., et al. Early increase in plasma parathyroid hormone levels following liver transplantation. J Hepatol 25 (1996) 715-718
24. Monegal A., Navasa M., Guanabens N., et al. Osteoporosis and bone mineral metabolism disorders in cirrhotic patients referred for orthotopic liver transplantation. Calcif Tissue Int 60 (1997) 148-154
25. Chen C.C., Wang S.S., Jeng F.S., et al. Metabolic bone disease of liver cirrhosis: is it parallel to the clinical severity of cirrhosis?. J Gastroenterol Hepatol 11 (1996) 417-421
26. Gonzalez-Calvin J.L., Gallego-Rojo F., Fernandez-Perez R., et al. Osteoporosis, mineral metabolism, and serum soluble tumor necrosis factor receptor p55 in viral cirrhosis. J Clin Endocrinol Metab 89 (2004) 4325-4330
27. Masuda S., Okano T., Osawa K., et al. Concentrations of vitamin D-binding protein and vitamin D metabolites in plasma of patients with liver cirrhosis. J Nutr Sci Vitaminol (Tokyo) 35 (1989) 225-234
28. Bouillon R., Auwerx J., Dekeyser L., et al. Serum vitamin D metabolites and their binding protein in patients with liver cirrhosis. J Clin Endocrinol Metab 59 (1984) 86-89
29. Dobak J., Grzybowski J., Liu F.T., et al. 1,25-dihydroxyvitamin D3 increases collagen production in dermal fibroblasts. J Dermatol Sci 8 (1994) 18-24
30. Koli K., and Keski-Oja J. 1alpha,25-dihydroxyvitamin D3 and its analogues down-regulate cell invasion-associated proteases in cultured malignant cells. Cell Growth Differ 11 (2000) 221-229
31. United Network for Organ Sharing (UNOS). MELD calculator. Available at: http://www.unos.org/resources/MeldPeldCalculator.asp?index=98. Accessed September 2, 2006.
32. Dawson-Hughes B., Heaney R.P., Holick M.F., et al. Estimates of optimal vitamin D status. Osteoporos Int 16 (2005) 713-716
33. Working Group of the Australian and New Zealand Bone and Mineral Society, Endocrine Society of Autralia, and Osteoporosis Australia. Vitamin D and adult bone health in Australia and New Zealand: a position statement. Med J Aust 182 (2005) 281-285
34. Mawer E.B., Klass H.J., Warnes T.W., et al. Metabolism of vitamin D in patients with primary biliary cirrhosis and alcoholic liver disease. Clin Sci (Lond) 69 (1985) 561-570
35. Mitchison H.C., Malcolm A.J., Bassendine M.F., et al. Metabolic bone disease in primary biliary cirrhosis at presentation. Gastroenterology 94 (1988) 463-470
36. Garcia-Valdecasas-Campelo E., Gonzalez-Reimers E., Santolaria-Fernandez F., et al. Serum osteoprotegerin and rank levels in chronic alcoholic liver disease. Alcohol Alcohol 41 (2006) 261-266
37. Schiefke I., Fach A., Wiedmann M., et al. Reduced bone mineral density and altered bone turnover markers in patients with non-cirrhotic chronic hepatitis B or C infection. World J Gastroenterol 11 (2005) 1843-1847
38. Gaudio A., Lasco A., Morabito N., et al. Hepatic osteodystrophy: does the osteoprotegerin/receptor activator of nuclear factor-kB ligand system play a role. J Endocrinol Invest 28 (2005) 677-682
39. Chow L.H., Frei J.V., Hodsman A.B., et al. Low serum 25-hydroxyvitamin D in hereditary hemochromatosis: relation to iron status. Gastroenterology 88 (1985) 865-869
40. Guggenbuhl P., Deugnier Y., Boisdet J.F., et al. Bone mineral density in men with genetic hemochromatosis and HFE gene mutation. Osteoporos Int 16 (2005) 1809-1814
41. Uretmen S., Gol M., Cimrin D., et al. Effects of chronic liver disease on bone mineral density and bone metabolism markers in postmenopausal women. Eur J Obstet Gynecol Reprod Biol 123 (2005) 67-71
42. Paliard P., Dumeril B., Romand-Monnier M., et al. [Influence of chronic alcoholism on plasma 25-hydroxycholecalciferol levels. Presse Med 12 (1983) 503-506
43. Bolt M.J., Sitrin M.D., Favus M.J., et al. Hepatic vitamin D 25-hydroxylase: inhibition by bile duct ligation or bile salts. Hepatology 1 (1981) 436-440
44. Caniggia A., Lore F., di Cairano G., et al. Main endocrine modulators of vitamin D hydroxylases in human pathophysiology. J Steroid Biochem 27 (1987) 815-824
45. Heaf J.G. Hepatic osteodystrophy. Scand J Gastroenterol 20 (1985) 1035-1040
46. Skinner R.K., Sherlock S., Long R.G., et al. 25-hydroxylation of vitamin D in primary biliary cirrhosis. Lancet 1 (1977) 720-721
47. Compston J.E. Hepatic osteodystrophy: vitamin D metabolism in patients with liver disease. Gut 27 (1986) 1073-1090
48. Ohyama Y., and Yamasaki T. Eight cytochrome P450s catalyze vitamin D metabolism. Front Biosci 9 (2004) 3007-3018
49. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 22 (2001) 477-501
50. Bischoff-Ferrari H.A., Willett W.C., Wong J.B., et al. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA 293 (2005) 2257-2264
51. Timms P.M., Mannan N., Hitman G.A., et al. Circulating MMP9, vitamin D and variation in the TIMP-1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders?. QJM 95 (2002) 787-796
52. Garciade Leon Mdel C., Montfort I., Tello Montes E., et al. Hepatocyte production of modulators of extracellular liver matrix in normal and cirrhotic rat liver. Exp Mol Pathol 80 (2006) 97-108
53. Khandoga A., Kessler J.S., Hanschen M., et al. Matrix metalloproteinase-9 promotes neutrophil and T cell recruitment and migration in the postischemic liver. J Leukoc Biol 79 (2006) 1295-1305
54. Selzner N., Rudiger H., Graf R., et al. Protective strategies against ischemic injury of the liver. Gastroenterology 125 (2003) 917-936
55. Millonig G., Graziadei I.W., Eichler D., et al. Alendronate in combination with calcium and vitamin D prevents bone loss after orthotopic liver transplantation: a prospective single-center study. Liver Transpl 11 (2005) 960-966
56. Binkley N., Krueger D., Cowgill C.S., et al. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab 89 (2004) 3152-3157
57. Heaney R.P. Functional indices of vitamin D status and ramifications of vitamin D deficiency. Am J Clin Nutr 80 (2004) 1706S-1709S
58. Fernandez E., Fibla J., Betriu A., et al. Association between vitamin D receptor gene polymorphism and relative hypoparathyroidism in patients with chronic renal failure. J Am Soc Nephrol 8 (1997) 1546-1552
59. Conigrave A.D., Mun H.C., Delbridge L., et al. L-amino acids regulate parathyroid hormone secretion. J Biol Chem 279 (2004) 38151-38159