Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes

Journal of Autoimmunity

Volumn 40, Issue 1, 2013, Pages 111-121

  Liubchenko, Ganna A ^a   Appleberry, Holly C ^a   Striebich, Christopher C ^a   Franklin, Karen E ^a   Derber, Lezlie A ^a   Holers, V Michael ^a   Lyubchenko, Taras ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

B cells; BCR signal transduction; Ca2+ signaling; Clonal anergy; Protein phosphorylation; Rheumatoid arthritis; Tolerance

Indexed keywords

AUTOANTIBODY; CALCIUM; CD19 ANTIGEN; CD27 ANTIGEN; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE SYK; PROTEIN TYROSINE PHOSPHATASE SHP 2; STRESS ACTIVATED PROTEIN KINASE;

ADULT; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CLINICAL ARTICLE; CLONAL ANERGY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MALE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGENS, CD19; ANTIGENS, CD27; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNITY; B-LYMPHOCYTES; CLONAL ANERGY; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION;

EID: 84873730087     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.09.001     Document Type: Article

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