Influence of particle size on the crystallization kinetics of amorphous felodipine powders

Powder Technology

Volumn 236, Issue , 2013, Pages 197-204

  Kestur, Umesh S ^a   Ivanesivic, Igor ^b   Alonzo, David E ^a   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

^b SSCI   (United States)

Author keywords

Amorphous; Dissolution; Growth rate; Particle size; Solid dispersion; Surface area

Indexed keywords

AMORPHOUS POWDERS; BULK CRYSTALLIZATION; CONCENTRATION-TIME; CRYSTALLINITIES; CRYSTALLIZATION RATES; DIFFERENT PARTICLE SIZES; DISSOLUTION PROFILES; FASTER RATES; FELODIPINE; FREE SURFACES; KINETIC PROFILES; POLYVINYL PYRROLIDONE; POWDER X-RAY DIFFRACTION (PXRD); RAPID CRYSTALLIZATION; SIZE DEPENDENT; SOLID DISPERSION; SURFACE AREA; SURFACE GROWTH; TIME-PERIODS;

AMORPHOUS MATERIALS; CRYSTALLIZATION KINETICS; DISPERSIONS; DISSOLUTION; GROWTH RATE; KINETICS; OPTICAL MICROSCOPY; POLYMERS; POWDERS; RAMAN SPECTROSCOPY; X RAY DIFFRACTION;

PARTICLE SIZE;

FELODIPINE; POVIDONE;

ARTICLE; CONCENTRATION (PARAMETERS); CRYSTALLIZATION; DISPERSION; DRUG SOLUBILITY; GLASS TRANSITION TEMPERATURE; KINETICS; MICROSCOPY; PARTICLE SIZE; POWDER; RAMAN SPECTROMETRY; X RAY POWDER DIFFRACTION;

EID: 84873729506     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.02.010     Document Type: Article

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