In vitro generation of a multilayered osteochondral construct with an osteochondral interface using rabbit bone marrow stromal cells and a silk peptide-based scaffold

Journal of Tissue Engineering and Regenerative Medicine

Volumn 10, Issue 4, 2016, Pages 284-293

  Chen, Kelei ^a   Shi, Pujiang ^a   Teh, Thomas Kok Hiong ^a   Toh, Siew Lok ^a   Goh, James Ch ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

BMSCs; Co culture; Multilayer; Osteochondral

Indexed keywords

BONE; CYTOLOGY; GENE EXPRESSION; PEPTIDES; SCAFFOLDS (BIOLOGY);

BIOCHEMICAL ANALYSIS; BMSC; BONE MARROW STROMAL CELLS; CHONDROGENIC; CO-CULTURES; IN-VITRO; MULTI-LAYERED; OSTEOCHONDRAL; OSTEOGENIC; TISSUES ENGINEERINGS;

CARTILAGE;

COLLAGEN TYPE 10; COLLAGENASE 3; SCAFFOLD PROTEIN; SILK FIBROIN; GLYCOSAMINOGLYCAN; PEPTIDE; SILK;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BONE MARROW STROMA CELL; BONE REGENERATION; BONE STRUCTURE; CARTILAGE CELL; COCULTURE; GENE EXPRESSION PROFILING; HISTOLOGY; IN VITRO STUDY; MARKER GENE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RABBIT; TISSUE ENGINEERING; ANIMAL; BOMBYX; BONE DEVELOPMENT; BONE MARROW CELL; CELL DIFFERENTIATION; CHEMISTRY; CHONDROGENESIS; CYTOLOGY; DRUG EFFECTS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STROMA CELL; METABOLISM; RABBITS AND HARES; TISSUE SCAFFOLD; ULTRASTRUCTURE;

ANIMALS; BOMBYX; BONE MARROW CELLS; CELL DIFFERENTIATION; CHONDROGENESIS; COCULTURE TECHNIQUES; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GLYCOSAMINOGLYCANS; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PEPTIDES; RABBITS; SILK; TISSUE SCAFFOLDS;

EID: 84873726444     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1708     Document Type: Article

References (55)

1. Allan KS, Pilliar RM, Wang J et al. 2007; Formation of biphasic constructs containing cartilage with a calcified zone interface. Tissue Eng 13(1): 167-177.
2. Bhosale AM, Richardson JB. 2008; Articular cartilage: structure, injuries and review of management. Br Med Bull 87(1): 77-95.
3. Boskey AL. 1992; Mineral-matrix interactions in bone and cartilage. Clin Orthop Relat Res 281: 244-274.
4. Cain EL, Clancy WG. 2001; Treatment algorithm for osteochondral injuries of the knee. Clin Sports Med 20(2): 321-+.
5. Cao T, Ho KH, Teoh SH. 2003; Scaffold design and in vitro study of osteochondral coculture in a three-dimensional porous polycaprolactone scaffold fabricated by fused deposition modeling. Tissue Eng 9: S103-S112.
6. Carlevaro MF, Cermelli S, Cancedda R et al. 2000; Vascular endothelial growth factor (VEGF) in cartilage neovascularization and chondrocyte differentiation: auto-paracrine role during endochondral bone formation. J Cell Sci 113(Pt 1): 59-69.
7. Chau Y, Luo Y, Cheung AC et al. 2008; Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides - A model for biofunctional scaffolds. Biomaterials 29(11): 1713-1719.
8. Chen K, Teh TK, Ravi S et al. 2012; Osteochondral interface generation by rabbit bone marrow stromal cells and osteoblasts coculture. Tissue Eng Part A 18(17-18): 1902-1911.
9. Cheng HW, Luk KD, Cheung KM et al. 2011; In vitro generation of an osteochondral interface from mesenchymal stem cell-collagen microspheres. Biomaterials 32(6): 1526-1535.
10. Csaki C, Schneider PR, Shakibaei M. 2008; Mesenchymal stem cells as a potential pool for cartilage tissue engineering. Ann Anat 190(5): 395-412.
11. Fan HB, Liu HF, Toh SL et al. 2008; Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold. Biomaterials 29(8): 1017-1027.
12. Galotto M, Campanile G, Banfi A et al. 1995; Chondrocyte and osteoblast differentiation stage-specific monoclonal antibodies as a tool to investigate the initial bone formation in developing chick embryo. Eur J Cell Biol 67(2): 99-105.
13. Gelain F, Horii A, Zhang SG. 2007; Designer self-assembling peptide scaffolds for 3-D tissue cell cultures and regenerative medicine. Macromol Biosci 7(5): 544-551.
14. Harley BA, Gibson LJ. 2008; In vivo and in vitro applications of collagen-GAG scaffolds. Chem Eng J 137(1): 102-121.
15. Ho ST, Cool SM, Hui JH et al. 2009; The influence of fibrin based hydrogels on the chondrogenic differentiation of human bone marrow stromal cells. Biomaterials 31(1): 38-47.
16. Hollister SJ. 2005; Porous scaffold design for tissue engineering. Nat Mater 4(7): 518-524.
17. Hunziker EB. 2002. Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthritis Cartilage 10(6): 432-463.
18. Jiang J, Nicoll SB, Lu HH. 2005; Co-culture of osteoblasts and chondrocytes modulates cellular differentiation in vitro. Biochem Biophys Res Commun 338(2): 762-770.
19. Karlsson C, Brantsing C, Svensson T et al. 2007; Differentiation of human mesenchymal stem cells and articular chondrocytes: analysis of chondrogenic potential and expression pattern of differentiation-related transcription factors. J Orthop Res 25(2): 152-163.
20. Keeney M, Pandit A. 2009; The osteochondral junction and its repair via bi-phasic tissue engineering scaffolds. Tissue Eng Part B Rev 15(1): 55-73.
21. Kellett CF, Boscainos PJ, Gross AE. 2006; Surgical options for articular defects of the knee. Expert Rev Med Devices 3(5): 585-593.
22. Khanarian NT, Jiang J, Wan LQ et al. 2012; A hydrogel-mineral composite scaffold for osteochondral interface tissue engineering. Tissue Eng Part A 18(5-6): 533-545
23. Kim YJ, Kim HJ, Im GI. 2008; PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs. Biochem Biophys Res Commun 373(1): 104-108.
24. Kisiday J, Jin M, Kurz B et al. 2002; Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci USA 99(15): 9996-10001.
25. Kon E, Delcogliano M, Filardo G et al. 2010; A novel nano-composite multi-layered biomaterial for treatment of osteochondral lesions: technique note and an early stability pilot clinical trial. Injury 41(7): 693-701.
26. Lefebvre V, Garofalo S, Decrombrugghe B. 1995; Type-x collagen gene-expression in mouse chondrocytes immortalized by a temperature-sensitive simian-virus-40 large tumor-antigen. J Cell Biol 128(1-2): 239-245.
27. Lewis PB, McCarty LP, Kang RW et al. 2006; Basic science and treatment options for articular cartilage injuries. J Orthop Sports Phys Ther 36(10): 717-727.
28. Liu HF, Fan HB, Toh SL et al. 2008; A comparison of rabbit mesenchymal stem cells and anterior cruciate ligament fibroblasts responses on combined silk scaffolds. Biomaterials 29(10): 1443-1453.
29. Liu W, Cui L, Cao YL. 2006; Bone reconstruction with bone marrow stromal cells. Methods Enzymol 420: 362-380.
30. Lu HH, Jiang J. 2006; Interface tissue engineering and the formulation of multiple-tissue systems. Adv Biochem Eng Biotechnol 102: 91-111.
31. Mackay AM, Beck SC, Murphy J et al. 1998; Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow. Tissue Eng 4(4): 415-428.
32. Mahmoudifar N, Doran PM. 2005; Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors. Biomaterials 26(34): 7012-7024.
33. Malafaya PB, Reis RL. 2009; Bilayered chitosan-based scaffolds for osteochondral tissue engineering: Influence of hydroxyapatite on in vitro cytotoxicity and dynamic bioactivity studies in a specific double-chamber bioreactor. Acta Biomater 5(2): 644-660.
34. Mandl EW, Jahr H, Koevoet JL et al. 2004; Fibroblast growth factor-2 in serum-free medium is a potent mitogen and reduces dedifferentiation of human ear chondrocytes in monolayer culture. Matrix Biol 23(4): 231-241.
35. Mano JF, Reis RL. 2007; Osteochondral defects: present situation and tissue engineering approaches. J Tissue Eng Regen Med 1(4): 261-273.
36. Martin I, Miot S, Barbero A et al. 2007; Osteochondral tissue engineering. J Biomech 40(4): 750-765.
37. Miao CL, Mu SC, Duan P et al. 2009; Effects of chondrogenic microenvironment on construction of cartilage tissues using marrow stromal cells in vitro. Artif Cell Blood Substit Biotechnol 37(5): 214-221.
38. Mohan N, Dormer NH, Caldwell KL et al. 2011; Continuous gradients of material composition and growth factors for effective regeneration of the osteochondral interface. Tissue Eng Part A 17(21-22): 2845-2855.
39. Mori G, Brunetti G, Oranger A et al. 2011; Dental pulp stem cells: osteogenic differentiation and gene expression. Ann N Y Acad Sci 1237: 47-52.
40. Moroni L, Schotel R, Hamann D et al. 2008; 3D fiber-deposited electrospun integrated scaffolds enhance cartilage tissue formation. Adv Funct Mater 18(1): 53-60.
41. Nanba Y, Nishida K, Yoshikawa T et al. 1997; Expression of osteonectin in articular cartilage of osteoarthritic knees. Acta Med Okayama 51(5): 239-243.
42. O'Shea TM, Miao XG. 2008; Bilayered scaffolds for osteochondral tissue engineering. Tissue Eng Part B Rev 14(4): 447-464.
43. Pick M, Azzola L, Mossman A et al. 2007; Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis. Stem Cells 25(9): 2206-2214.
44. Sahoo S, Toh SL, Goh JC. 2011; A bFGF-releasing silk/PLGA-based biohybrid scaffold for ligament/tendon tissue engineering using mesenchymal progenitor cells. Biomaterials 31(11):2990-2998.
45. Sanchez C, Deberg MA, Piccardi N et al. 2005; Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes. Osteoarthritis Cartilage 13(11): 988-997.
46. Spalazzi JP, Doty SB, Moffat KL et al. 2006; Development of controlled matrix heterogeneity on a triphasic scaffold for orthopedic interface tissue engineering. Tissue Eng 12(12): 3497-3508.
47. Tan PH, Aung KZ, Toh SL et al. 2011; Three-dimensional porous silk tumor constructs in the approximation of in vivo osteosarcoma physiology. Biomaterials 32(26): 6131-6137.
48. Vepari C, Kaplan DL. 2007; Silk as a biomaterial. Prog Polym Sci 32(8-9):991-1007.
49. Wang Y, Kim UJ, Blasioli DJ et al. 2005; In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells. Biomaterials 26(34): 7082-7294.
50. Wang YZ, Kim HJ, Vunjak-Novakovic G et al. 2006; Stem cell-based tissue engineering with silk biomaterials. Biomaterials 27(36): 6064-6082.
51. Wei L, Kanbe K, Lee M et al. 2010; Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation. Dev Biol 341(1): 236-245.
52. Wu YN, Yang Z, Hui JH et al. 2007; Cartilaginous ECM component-modification of the micro-bead culture system for chondrogenic differentiation of mesenchymal stem cells. Biomaterials 28(28): 4056-4067.
53. Yang PJ, Temenoff JS. 2009; Engineering orthopedic tissue interfaces. Tissue Eng Part B Rev 15(2): 127-141.
54. Zhang S, Gelain F, Zhao X. 2005; Designer self-assembling peptide nanofiber scaffolds for 3D tissue cell cultures. Semin Cancer Biol 15(5): 413-420.
55. Zou LJ, Zou XN, Chen L et al. 2008; Effect of hyaluronan on osteogenic differentiation of porcine bone marrow stromal cells in vitro. J Orthop Res 26(5): 713-720.