In vitro generation of an osteochondral interface from mesenchymal stem cell-collagen microspheres

Biomaterials

Volumn 32, Issue 6, 2011, Pages 1526-1535

  Cheng, Hiu wa ^a   Luk, Keith D K ^b   Cheung, Kenneth M C ^b   Chan, Barbara P ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Calcified cartilage; Collagen microspheres; Complex tissue engineering; Mesenchymal stem cells; Microencapsulation; Osteochondral interface

Indexed keywords

BIOCHEMISTRY; CARTILAGE; CELL CULTURE; CELL ENGINEERING; COLLAGEN; FAILURE (MECHANICAL); MICROENCAPSULATION; MICROSPHERES; STEM CELLS; SURFACE CHEMISTRY; TISSUE;

BIOLOGICAL INTERFACE; EXTRACELLULAR MATRICES; HYPERTROPHIC CHONDROCYTES; INTERFACE FORMATION; INTERFACE REGIONS; MECHANICAL FAILURES; MESENCHYMAL STEM CELL; OSTEOCHONDRAL;

TISSUE ENGINEERING;

COLLAGEN; MICROSPHERE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL INTERACTION; COCULTURE; COMPLEX FORMATION; CONTROLLED STUDY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MESENCHYMAL STEM CELL; MICROENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; TISSUE ENGINEERING;

BIOCHEMISTRY; CHEMISTRY; COLLAGEN; MICROSPHERES; PACKAGING; SURFACE PROPERTIES;

EID: 78650293523     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.10.021     Document Type: Article

References (44)

1. Place E.S., Evans N.D., Stevens M.M. Complexity in biomaterials for tissue engineering. Nat Mater 2009, 8:457-470.
2. Broom N.D., Poole C.A. A functional-morphological study of the tidemark region of articular cartilage maintained in a non-viable physiological condition. J Anat 1982, 135:65-82.
3. Yang P.J., Temenoff J.S. Engineering orthopedic tissue interfaces. Tissue Eng Part B Rev 2009, 15:127-141.
4. Keeney M., Pandit A. The osteochondral junction and its repair via bi-phasic tissue engineering scaffolds. Tissue Eng Part B Rev 2009, 15:55-73.
5. Oegema T.R., Carpenter R.J., Hofmeister F., Thompson R.C. The interaction of the zone of calcified cartilage and subchondral bone in osteoarthritis. Microsc Res Tech 1997, 37:324-332.
6. Wang I.N., Lu H.H. Role of cell-cell interactions on the regeneration of soft tissue-to-bone interface. Conf Proc IEEE Eng Med Biol Soc 2006, 1:783-786.
7. Lu H.H., Wang I.N.E. Multiscale coculture models for orthopedic interface tissue engineering. Biomedical Nanostructures 2008, 357-373. John Wiley & Sons, New Jersey. K.E. Gonsalves, C.R. Halberstadt, C.T. Laurencin, L.S. Nair (Eds.).
8. Martin I., Miot S., Barbero A., Jakob M., Wendt D. Osteochondral tissue engineering. J Biomech 2007, 40:750-765.
9. O'Shea T.M., Miao X. Bilayered scaffolds for osteochondral tissue engineering. Tissue Eng Part B Rev 2008, 14:447-464.
10. Sherwood J.K., Riley S.L., Palazzolo R., Brown S.C., Monkhouse D.C., Coates M., et al. A three-dimensional osteochondral composite scaffold for articular cartilage repair. Biomaterials 2002, 23:4739-4751.
11. Dormer N.H., Singh M., Wang L., Berkland C.J., Detamore M.S. Osteochondral interface tissue engineering using macroscopic gradients of bioactive signals. Ann Biomed Eng 2010, 38:2167-2182.
12. Alhadlaq A., Mao J.J. Tissue-engineered osteochondral constructs in the shape of an articular condyle. J Bone Joint Surg Am 2005, 87:936-944.
13. Jiang J., Nicoll S.B., Lu H.H. Co-culture of osteoblasts and chondrocytes modulates cellular differentiation in vitro. Biochem Biophys Res Commun 2005, 338:762-770.
14. Wang I.E., Shan J., Choi R., Oh S., Kepler C.K., Chen F.H., et al. Role of osteoblast-fibroblast interactions in the formation of the ligament-to-bone interface. J Orthop Res 2007, 25:1609-1620.
15. Chan B.P., Hui T.Y., Wong M.Y., Yip K.H., Chan G.C. Mesenchymal stem cell-encapsulated collagen microspheres for bone tissue engineering. Tissue Eng Part C Methods 2010, 16:225-235.
16. Chan B.P., Hui T.Y., Yeung C.W., Li J., Mo I., Chan G.C. Self-assembled collagen-human mesenchymal stem cell microspheres for regenerative medicine. Biomaterials 2007, 28:4652-4666.
17. Hui T.Y., Cheung K.M., Cheung W.L., Chan D., Chan B.P. In vitro chondrogenic differentiation of human mesenchymal stem cells in collagen microspheres: Influence of cell seeding density and collagen concentration. Biomaterials 2008, 29:3201-3212.
18. Barbosa I., Garcia S., Barbier-Chassefière V., Caruelle J.P., Martelly I., Papy-García D. Improved and simple micro assay for sulfated glycosaminoglycans quantification in biological extracts and its use in skin and muscle tissue studies. Glycobiology 2003, 13:647-653.
19. Manoury B., Nenan S., Guenon I., Boichot E., Planquois J.M., Bertrand C.P., et al. Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice. J Inflamm (Lond) 2006, 3:2-9.
20. D'Amore A., Stella J.A., Wagner W.R., Sacks M.S. Characterization of the complete fiber network topology of planar fibrous tissues and scaffolds. Biomaterials 2010, 31:5345-5354.
21. King K.B., Opel C.F., Rempel D.M. Cyclical articular joint loading leads to cartilage thinning and osteopontin production in a novel in vivo rabbit model of repetitive finger flexion. Osteoarthr Cartil 2005, 13:971-978.
22. Hoogendoorn R., Doulabi B.Z., Huang C.L., Wuisman P.I., Bank R.A., Helder M.N. Molecular changes in the degenerated goat intervertebral disc. Spine 2008, 33:1714-1721.
23. Mwale F., Roughley P., Antoniou J. Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc. Eur Cell Mater 2004, 8:58-64.
24. Young D.M., Fioravanti J.L., Olson H.M., Prieur D.J. Chemical and morphologic alterations of rabbit bone induced by adriamycin. Calcif Tissue Res 1975, 18:47-63.
25. Chachra D., Turner C.H., Dunipace A.J., Grynpas M.D. The effect of fluoride treatment on bone mineral in rabbits. Calcif Tissue Int 1999, 64:345-351.
26. Dorozhkin S.V., Epple M. Biological and medical significance of calcium phosphates. Angew Chem Int Ed Engl 2002, 41:3130-3146.
27. Ballock R.T., Heydemann A., Wakefield L.M., Flanders K.C., Roberts A.B., Sporn M.B. TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. Dev Biol 1993, 158:414-429.
28. Zhang X., Ziran N., Goater J.J., Schwarz E.M., Puzas J.E., Rosier R.N., et al. Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation. Bone 2004, 34:809-817.
29. Mackay A.M., Beck S.C., Murphy J.M., Barry F.P., Chichester C.O., Pittenger M.F. Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow. Tissue Eng 1998, 4:415-428.
30. Mueller M.B., Tuan R.S. Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells. Arthritis Rheum 2008, 58:1377-1388.
31. Wang L., Shao Y.Y., Ballock R.T. Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signaling. J Bone Miner Res 2010, 25:1138-1146.
32. Leboy P.S., Sullivan T.A., Nooreyazdan M., Venezian R.A. Rapid chondrocyte maturation by serum-free culture with BMP-2 and ascorbic acid. J Cell Biochem 1997, 66:394-403.
33. Steinert A.F., Proffen B., Kunz M., Hendrich C., Ghivizzani S.C., Nöth U., et al. Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther 2009, 11:R148.
34. Yu H., Grynpas M., Kandel R.A. Composition of cartilaginous tissue with mineralized and non-mineralized zones formed in vitro. Biomaterials 1997, 18:1425-1431.
35. Kandel R.A., Grynpas M., Pilliar R., Lee J., Wang J., Waldman S., et al. Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model. Biomaterials 2006, 27:4120-4131.
36. Allan K.S., Pilliar R.M., Wang J., Grynpas M.D., Kandel R.A. Formation of biphasic constructs containing cartilage with a calcified zone interface. Tissue Eng 2007, 13:167-177.
37. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284:143-147.
38. Le Blanc K., Rasmusson I., Sundberg B., Götherström C., Hassan M., Uzunel M., et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004, 363:1439-1441.
39. Augst A., Marolt D., Freed L.E., Vepari C., Meinel L., Farley M., et al. Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem cells, silk scaffolds and bioreactors. J R Soc Interface 2008, 5:929-939.
40. Tuli R., Nandi S., Li W.J., Tuli S., Huang X., Manner P.A. Human mesenchymal progenitor cell-based tissue engineering of a single-unit osteochondral construct. Tissue Eng 2004, 10:1169-1179.
41. Lindsey W.H., Ogle R.C., Morgan R.F., Cantrell R.W., Sweeney T.M. Nasal reconstruction using an osteoconductive collagen gel matrix. Arch Otolaryngol Head Neck Surg 1996, 122:37-40.
42. Zheng L., Fan H.S., Sun J., Chen X.N., Wang G., Zhang L., et al. Chondrogenic differentiation of mesenchymal stem cells induced by collagen-based hydrogel: an in vivo study. J Biomed Mater Res A 2010, 93:783-792.
43. Wong M., Carter D.R. Articular cartilage functional histomorphology and mechanobiology: a research perspective. Bone 2003, 33:1-13.
44. Au-Yeung K.L., Sze K.Y., Sham M.H., Chan B.P. Development of a micromanipulator-based loading device for mechanoregulation study of human mesenchymal stem cells in 3D collagen constructs. Tissue Eng Part C Methods 2010, 16:93-107.