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Volumn 1, Issue 4, 2012, Pages 289-297

Functional impairment of human resident cardiac stem cells by the cardiotoxic Antineoplastic agent trastuzumab

Author keywords

Adult stem cells; Angiogenesis; Cardiac; Chemotherapy

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; CD31 ANTIGEN; CD34 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR TBX5; TRASTUZUMAB; TROPOMYOSIN; TROPONIN I; ANTINEOPLASTIC AGENT; CARDIOTOXIN; ERBB2 PROTEIN, HUMAN; MESSENGER RNA; MONOCLONAL ANTIBODY; MUSCLE PROTEIN;

EID: 84873712445     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2011-0016     Document Type: Article
Times cited : (34)

References (47)
  • 2
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005;353:1659-1672.
    • (2005) N Engl J Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 3
    • 26844536978 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    • Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005;353:1673-1684.
    • (2005) N Engl J Med , vol.353 , pp. 1673-1684
    • Romond, E.H.1    Perez, E.A.2    Bryant, J.3
  • 4
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344:783-792.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 5
    • 0036498781 scopus 로고    scopus 로고
    • Cardiac dysfunction in the trastuzumab clinical trials experience
    • Seidman A, Hudis C, Pierri MK et al. Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 2002;20:1215-1221.
    • (2002) J Clin Oncol , vol.20 , pp. 1215-1221
    • Seidman, A.1    Hudis, C.2    Pierri, M.K.3
  • 6
    • 78649835433 scopus 로고    scopus 로고
    • Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair
    • Li TS, Cheng K, Lee ST et al. Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair. STEM CELLS 2010; 28:2088-2098.
    • (2010) STEM CELLS , vol.28 , pp. 2088-2098
    • Li, T.S.1    Cheng, K.2    Lee, S.T.3
  • 7
    • 7244261795 scopus 로고    scopus 로고
    • Isolation and expansion of adult cardiac stem cells from human and murine heart
    • Messina E, De Angelis L, Frati G et al. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 2004; 95:911-921.
    • (2004) Circ Res , vol.95 , pp. 911-921
    • Messina, E.1    de Angelis, L.2    Frati, G.3
  • 8
    • 33847145871 scopus 로고    scopus 로고
    • Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens
    • Smith RR, Barile L, Cho HC et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 2007;115:896-908.
    • (2007) Circulation , vol.115 , pp. 896-908
    • Smith, R.R.1    Barile, L.2    Cho, H.C.3
  • 9
    • 77950890007 scopus 로고    scopus 로고
    • Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    • Chimenti I, Smith RR, Li TS et al. Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 2010;106:971-980.
    • (2010) Circ Res , vol.106 , pp. 971-980
    • Chimenti, I.1    Smith, R.R.2    Li, T.S.3
  • 10
    • 56349146612 scopus 로고    scopus 로고
    • Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction
    • Takehara N, Tsutsumi Y, Tateishi K et al. Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction. J Am Coll Cardiol 2008;52:1858-1865.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1858-1865
    • Takehara, N.1    Tsutsumi, Y.2    Tateishi, K.3
  • 11
    • 66949162281 scopus 로고    scopus 로고
    • Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression
    • Tang YL, Zhu W, Cheng M et al. Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression. Circ Res 2009;104:1209-1216.
    • (2009) Circ Res , vol.104 , pp. 1209-1216
    • Tang, Y.L.1    Zhu, W.2    Cheng, M.3
  • 12
    • 70349663946 scopus 로고    scopus 로고
    • Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue
    • Davis DR, Zhang Y, Smith RR et al. Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLoS One 2009;4:e7195.
    • (2009) PLoS One , vol.4
    • Davis, D.R.1    Zhang, Y.2    Smith, R.R.3
  • 13
    • 42549156555 scopus 로고    scopus 로고
    • 2+ exchanger report cardiogenic differentiation in stem cells
    • 2+ exchanger report cardiogenic differentiation in stem cells. Mol Ther 2008;16: 957-964.
    • (2008) Mol Ther , vol.16 , pp. 957-964
    • Barth, A.S.1    Kizana, E.2    Smith, R.R.3
  • 14
    • 32944458087 scopus 로고    scopus 로고
    • Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts
    • du Manoir JM, Francia G, Man S et al. Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts. Clin Cancer Res 2006;12:904-916.
    • (2006) Clin Cancer Res , vol.12 , pp. 904-916
    • du Manoir, J.M.1    Francia, G.2    Man, S.3
  • 15
    • 43149119978 scopus 로고    scopus 로고
    • Cardiogenic small molecules that enhance myocardial repair by stem cells
    • Sadek H, Hannack B, Choe E et al. Cardiogenic small molecules that enhance myocardial repair by stem cells. Proc Natl Acad Sci USA 2008;105:6063-6068.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6063-6068
    • Sadek, H.1    Hannack, B.2    Choe, E.3
  • 16
    • 34447526684 scopus 로고    scopus 로고
    • Myocardial infarct size measurement in the mouse chronic infarction model: Comparison of area-and length-based approaches
    • Takagawa J, Zhang Y, Wong ML et al. Myocardial infarct size measurement in the mouse chronic infarction model: Comparison of area-and length-based approaches. J Appl Physiol 2007;102:2104-2111.
    • (2007) J Appl Physiol , vol.102 , pp. 2104-2111
    • Takagawa, J.1    Zhang, Y.2    Wong, M.L.3
  • 17
    • 33947310406 scopus 로고    scopus 로고
    • Cell isolation procedures matter: A comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction
    • Seeger FH, Tonn T, Krzossok N et al. Cell isolation procedures matter: A comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction. Eur Heart J 2007;28:766-772.
    • (2007) Eur Heart J , vol.28 , pp. 766-772
    • Seeger, F.H.1    Tonn, T.2    Krzossok, N.3
  • 18
    • 77953726551 scopus 로고    scopus 로고
    • Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies
    • Davis DR, Kizana E, Terrovitis J et al. Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies. J Mol Cell Cardiol 2010;49:312-321.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 312-321
    • Davis, D.R.1    Kizana, E.2    Terrovitis, J.3
  • 19
    • 77952242273 scopus 로고    scopus 로고
    • Human cardiospheres are a source of stem cells with cardiomyogenic potential
    • Davis DR, Ruckdeschel Smith R, Marban E. Human cardiospheres are a source of stem cells with cardiomyogenic potential. STEM CELLS 2010;28:903-904.
    • (2010) STEM CELLS , vol.28 , pp. 903-904
    • Davis, D.R.1    Ruckdeschel, S.R.2    Marban, E.3
  • 20
    • 70349661889 scopus 로고    scopus 로고
    • Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy
    • Johnston PV, Sasano T, Mills K et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 2009;120:1075-1083.
    • (2009) Circulation , vol.120 , pp. 1075-1083
    • Johnston, P.V.1    Sasano, T.2    Mills, K.3
  • 21
    • 74949120679 scopus 로고    scopus 로고
    • Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction
    • Tang XL, Rokosh G, Sanganalmath SK et al. Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 2010;121:293-305.
    • (2010) Circulation , vol.121 , pp. 293-305
    • Tang, X.L.1    Rokosh, G.2    Sanganalmath, S.K.3
  • 22
    • 77955169883 scopus 로고    scopus 로고
    • Transplantation of cardiac progenitor cell sheet onto infarcted heart promotes cardiogenesis and improves function
    • Zakharova L, Mastroeni D, Mutlu N et al. Transplantation of cardiac progenitor cell sheet onto infarcted heart promotes cardiogenesis and improves function. Cardiovasc Res 2010;87:40-49.
    • (2010) Cardiovasc Res , vol.87 , pp. 40-49
    • Zakharova, L.1    Mastroeni, D.2    Mutlu, N.3
  • 23
    • 70349728450 scopus 로고    scopus 로고
    • Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery
    • Terrovitis J, Lautamaki R, Bonios M et al. Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery. J Am Coll Cardiol 2009;54:1619-1626.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1619-1626
    • Terrovitis, J.1    Lautamaki, R.2    Bonios, M.3
  • 24
    • 77955284228 scopus 로고    scopus 로고
    • Longer-term assessment of trastuzumabrelated cardiac adverse events in the Herceptin Adjuvant (HERA) trial
    • Procter M, Suter TM, de Azambuja E et al. Longer-term assessment of trastuzumabrelated cardiac adverse events in the Herceptin Adjuvant (HERA) trial. J Clin Oncol 2010;28: 3422-3428.
    • (2010) J Clin Oncol , vol.28 , pp. 3422-3428
    • Procter, M.1    Suter, T.M.2    de Azambuja, E.3
  • 25
    • 77955284952 scopus 로고    scopus 로고
    • Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosphamide followed by trastuzumab adjuvant therapy: A combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials
    • Russell SD, Blackwell KL, Lawrence J et al. Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosphamide followed by trastuzumab adjuvant therapy: A combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials. J Clin Oncol 2010;28:3416-3421.
    • (2010) J Clin Oncol , vol.28 , pp. 3416-3421
    • Russell, S.D.1    Blackwell, K.L.2    Lawrence, J.3
  • 26
    • 33748642331 scopus 로고    scopus 로고
    • Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: The M.D. Anderson Cancer Center experience
    • Guarneri V, Lenihan DJ, Valero V et al. Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: The M.D. Anderson Cancer Center experience. J Clin Oncol 2006;24:4107-4115.
    • (2006) J Clin Oncol , vol.24 , pp. 4107-4115
    • Guarneri, V.1    Lenihan, D.J.2    Valero, V.3
  • 27
    • 34548152541 scopus 로고    scopus 로고
    • Trastuzumab-related cardiotoxicity: Calling into question the concept of reversibility
    • Telli ML, Hunt SA, Carlson RW, Guardino AE. Trastuzumab-related cardiotoxicity: Calling into question the concept of reversibility. J Clin Oncol 2007;25:3525-3533.
    • (2007) J Clin Oncol , vol.25 , pp. 3525-3533
    • Telli, M.L.1    Hunt, S.A.2    Carlson, R.W.3    Guardino, A.E.4
  • 28
    • 0028785406 scopus 로고
    • Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
    • Gassmann M, Casagranda F, Orioli D et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 1995;378:390-394.
    • (1995) Nature , vol.378 , pp. 390-394
    • Gassmann, M.1    Casagranda, F.2    Orioli, D.3
  • 29
    • 0028884413 scopus 로고
    • Requirement for neuregulin receptor erbB2 in neural and cardiac development
    • Lee KF, Simon H, Chen H et al. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995;378:394-398.
    • (1995) Nature , vol.378 , pp. 394-398
    • Lee, K.F.1    Simon, H.2    Chen, H.3
  • 30
    • 0028827104 scopus 로고
    • Multiple essential functions of neuregulin in development
    • Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995;378:386-390.
    • (1995) Nature , vol.378 , pp. 386-390
    • Meyer, D.1    Birchmeier, C.2
  • 31
    • 0032562770 scopus 로고    scopus 로고
    • Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
    • Zhao YY, Sawyer DR, Baliga RR et al. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 1998;273:10261-10269.
    • (1998) J Biol Chem , vol.273 , pp. 10261-10269
    • Zhao, Y.Y.1    Sawyer, D.R.2    Baliga, R.R.3
  • 32
    • 0037172982 scopus 로고    scopus 로고
    • Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
    • Ozcelik C, Erdmann B, Pilz B et al. Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci USA 2002;99: 8880-8885.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8880-8885
    • Ozcelik, C.1    Erdmann, B.2    Pilz, B.3
  • 33
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann O, Bhardwaj RD, Bernard S et al. Evidence for cardiomyocyte renewal in humans. Science 2009;324:98-102.
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1    Bhardwaj, R.D.2    Bernard, S.3
  • 34
    • 77955172516 scopus 로고    scopus 로고
    • Cardiomyogenesis in the adult human heart
    • Kajstura J, Urbanek K, Perl S et al. Cardiomyogenesis in the adult human heart. Circ Res 2010;107:305-315.
    • (2010) Circ Res , vol.107 , pp. 305-315
    • Kajstura, J.1    Urbanek, K.2    Perl, S.3
  • 35
    • 10744228523 scopus 로고    scopus 로고
    • Adult cardiac stem cells are multipotent and support myocardial regeneration
    • Beltrami AP, Barlucchi L, Torella D et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003; 114:763-776.
    • (2003) Cell , vol.114 , pp. 763-776
    • Beltrami, A.P.1    Barlucchi, L.2    Torella, D.3
  • 36
    • 0142027772 scopus 로고    scopus 로고
    • Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
    • Oh H, Bradfute SB, Gallardo TD et al. Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA 2003; 100: 12313-12318.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12313-12318
    • Oh, H.1    Bradfute, S.B.2    Gallardo, T.D.3
  • 37
    • 0347623124 scopus 로고    scopus 로고
    • Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart
    • Martin CM, Meeson AP, Robertson SM et al. Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. Develop Biol 2004;265:262-275.
    • (2004) Develop Biol , vol.265 , pp. 262-275
    • Martin, C.M.1    Meeson, A.P.2    Robertson, S.M.3
  • 38
    • 84864323035 scopus 로고    scopus 로고
    • Intrinsic cardiac origin of human cardiospherederived cells
    • (in press)
    • White AJ, Smith RR, Matsushita S, et al. Intrinsic cardiac origin of human cardiospherederived cells. Eur Heart J 2011 (in press).
    • (2011) Eur Heart J
    • White, A.J.1    Smith, R.R.2    Matsushita, S.3
  • 39
    • 77953023119 scopus 로고    scopus 로고
    • Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction
    • Cheng K, Li TS, Malliaras K, et al. Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction. Circ Res 2010;106:1570-1581.
    • (2010) Circ Res , vol.106 , pp. 1570-1581
    • Cheng, K.1    Li, T.S.2    Malliaras, K.3
  • 41
    • 79959858737 scopus 로고    scopus 로고
    • Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: Differential expression of microRNA
    • Sun M, Yan X, Bian Y et al. Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: Differential expression of microRNA. Am J Physiol Cell Physiol 2011;301:C21-C30.
    • (2011) Am J Physiol Cell Physiol , vol.301
    • Sun, M.1    Yan, X.2    Bian, Y.3
  • 42
    • 58549114851 scopus 로고    scopus 로고
    • Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells
    • Wang Z, Xu G, Wu Y et al. Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells. Med Biol Eng Comput 2009;47:41-48.
    • (2009) Med Biol Eng Comput , vol.47 , pp. 41-48
    • Wang, Z.1    Xu, G.2    Wu, Y.3
  • 43
    • 77957270888 scopus 로고    scopus 로고
    • Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells
    • Zhu WZ, Xie Y, Moyes KW et al. Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells. Circ Res 2010;107:776-786.
    • (2010) Circ Res , vol.107 , pp. 776-786
    • Zhu, W.Z.1    Xie, Y.2    Moyes, K.W.3
  • 44
    • 62649156293 scopus 로고    scopus 로고
    • The inhibitory effects of trastuzumab on corneal neovascularization
    • e2
    • Güler M, Yilmaz T, Ozercan I et al. The inhibitory effects of trastuzumab on corneal neovascularization. Am J Ophthalmol 2009; 147:703-708.e2.
    • (2009) Am J Ophthalmol , vol.147 , pp. 703-708
    • Güler, M.1    Yilmaz, T.2    Ozercan, I.3
  • 45
    • 0037149539 scopus 로고    scopus 로고
    • Tumour biology: Herceptin acts as an anti-angiogenic cocktail
    • Izumi Y, Xu L, et al.Tumour biology: Herceptin acts as an anti-angiogenic cocktail. Nature 2002;416:279-280.
    • (2002) Nature , vol.416 , pp. 279-280
    • Izumi, Y.1    Xu, L.2    di Tomaso, E.3
  • 46
    • 0037233190 scopus 로고    scopus 로고
    • Angiogenesis assays: A critical overview
    • Auerbach R, Lewis R, Shinners B et al. Angiogenesis assays: A critical overview. Clin Chem 2003;49:32-40.
    • (2003) Clin Chem , vol.49 , pp. 32-40
    • Auerbach, R.1    Lewis, R.2    Shinners, B.3
  • 47
    • 77949560537 scopus 로고    scopus 로고
    • Red blood cell contamination of the final cell product impairs the efficacy of autologous bone marrow mononuclear cell therapy
    • Assmus B, Tonn T, Seeger FH et al. Red blood cell contamination of the final cell product impairs the efficacy of autologous bone marrow mononuclear cell therapy. J Am Coll Cardiol 2010;55:1385-1394.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1385-1394
    • Assmus, B.1    Tonn, T.2    Seeger, F.H.3


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