Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cells

Nutrition and Cancer

Volumn 65, Issue 1, 2013, Pages 118-125

  Wang, Li Shu ^a   Kuo, Chieh Ti ^a   Cho, Seung Ju ^a   Seguin, Claire ^b   Siddiqui, Jibran ^a   Stoner, Kristen ^b   Yu IWeng, ^a   Huang, Tim H M ^c   Tichelaar, Jay ^a   Yearsley, Martha ^d   Stoner, Gary D ^a   Huang, Yi Wen ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c San Antonio Cancer Institute   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHOCYANIN; BETA CATENIN; CYANIDIN 3 O GLUCOSIDE; CYANIDIN 3 O SAMBUBIOSIDE; CYANIDIN 3 O XYLOSYLRUTINOSIDE; CYANIDINA 3 O RUTINOSIDE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; MESSENGER RNA; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 5; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER PATIENT; CELL PROLIFERATION; COLORECTAL CANCER; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LYMPHOMA; ONCOGENE C MYC; PROTEIN EXPRESSION; RASPBERRY; TREATMENT DURATION; TUMOR SUPPRESSOR GENE; WNT SIGNALING PATHWAY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTHOCYANINS; CACO-2 CELLS; CELL LINE, TUMOR; COLONIC NEOPLASMS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; ENZYME INHIBITORS; EYE PROTEINS; GENES, P16; GENES, TUMOR SUPPRESSOR; HUMANS; MEMBRANE PROTEINS; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; ROSACEAE;

RUBUS OCCIDENTALIS;

EID: 84873705144     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2013.741759     Document Type: Article

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