메뉴 건너뛰기




Volumn 103, Issue 10, 2004, Pages 3883-3889

Internal and external autocrine VEGF/KDR loops regulate survival of subsets of acute leukemia through distinct signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR REL; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

EID: 2342486598     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-05-1634     Document Type: Article
Times cited : (158)

References (34)
  • 1
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 1999;13:9-22.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 2
    • 0034499732 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and the regulation of angiogenesis
    • Ferrara N. Vascular endothelial growth factor and the regulation of angiogenesis. Recent Prog Horm Res. 2000;55:15-35.
    • (2000) Recent Prog Horm Res , vol.55 , pp. 15-35
    • Ferrara, N.1
  • 3
    • 0033604614 scopus 로고    scopus 로고
    • Signaling via vascular endothelial growth factor receptors
    • Petrova TV, Makinen T, Alitalo K. Signaling via vascular endothelial growth factor receptors. Exp Cell Res. 1999;253:117-130.
    • (1999) Exp Cell Res , vol.253 , pp. 117-130
    • Petrova, T.V.1    Makinen, T.2    Alitalo, K.3
  • 4
    • 0034681392 scopus 로고    scopus 로고
    • Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation
    • Wu LW, Mayo LD, Dunbar JD, et al. Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation. J Biol Chem. 2000;275:5096-5103.
    • (2000) J Biol Chem , vol.275 , pp. 5096-5103
    • Wu, L.W.1    Mayo, L.D.2    Dunbar, J.D.3
  • 5
    • 0035283119 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes
    • Bellamy WT, Richter L, Sirjani D, et al. Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes. Blood. 2001;97: 1427-1434.
    • (2001) Blood , vol.97 , pp. 1427-1434
    • Bellamy, W.T.1    Richter, L.2    Sirjani, D.3
  • 6
    • 0033861874 scopus 로고    scopus 로고
    • Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration
    • Dias S, Hattori K, Zhu Z, et al. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest. 2000;106: 511-521.
    • (2000) J Clin Invest , vol.106 , pp. 511-521
    • Dias, S.1    Hattori, K.2    Zhu, Z.3
  • 7
    • 0035845561 scopus 로고    scopus 로고
    • Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias
    • Dias S, Hattori K, Heissig B, et al. Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc Natl Acad Sci U S A. 2001;98:10857-10862.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10857-10862
    • Dias, S.1    Hattori, K.2    Heissig, B.3
  • 8
    • 0037137903 scopus 로고    scopus 로고
    • Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy
    • Lu D, Jimenez X, Zhang H, et al. Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy. Int J Cancer. 2002;97: 393-399.
    • (2002) Int J Cancer , vol.97 , pp. 393-399
    • Lu, D.1    Jimenez, X.2    Zhang, H.3
  • 9
    • 0035217589 scopus 로고    scopus 로고
    • Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases
    • Solorzano CC, Baker CH, Bruns CJ, et al. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biother Radiopharm. 2001;16:359-370.
    • (2001) Cancer Biother Radiopharm , vol.16 , pp. 359-370
    • Solorzano, C.C.1    Baker, C.H.2    Bruns, C.J.3
  • 10
    • 0037182861 scopus 로고    scopus 로고
    • VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
    • Gerber HP, Malik AK, Solar GP, et al. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature. 2002; 417:954-958.
    • (2002) Nature , vol.417 , pp. 954-958
    • Gerber, H.P.1    Malik, A.K.2    Solar, G.P.3
  • 11
    • 0035793623 scopus 로고    scopus 로고
    • Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2): A reassessment using novel receptor-specific vascular endothelial growth factor mutants
    • Gille H, Kowalski J, Li B, et al. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2): a reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem. 2001;276:3222-3230.
    • (2001) J Biol Chem , vol.276 , pp. 3222-3230
    • Gille, H.1    Kowalski, J.2    Li, B.3
  • 12
    • 0037313641 scopus 로고    scopus 로고
    • p38 MAP kinase-a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability
    • Issbrucker K, Marti HH, Hippenstiel S, et al. p38 MAP kinase-a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability. FASEB J. 2003;17:262-264.
    • (2003) FASEB J , vol.17 , pp. 262-264
    • Issbrucker, K.1    Marti, H.H.2    Hippenstiel, S.3
  • 13
    • 0034945841 scopus 로고    scopus 로고
    • Heterogeneity of the signal transduction pathways for VEGF-induced MAPKs activation in human vascular endothelial cells
    • Yashima R, Abe M, Tanaka K, et al. Heterogeneity of the signal transduction pathways for VEGF-induced MAPKs activation in human vascular endothelial cells. J Cell Physiol. 2001;188:201-210.
    • (2001) J Cell Physiol , vol.188 , pp. 201-210
    • Yashima, R.1    Abe, M.2    Tanaka, K.3
  • 14
    • 0034668149 scopus 로고    scopus 로고
    • Nuclear factor-kappa B, cancer, and apoptosis
    • Bours V, Bentires-Alj M, Hellin AC, et al. Nuclear factor-kappa B, cancer, and apoptosis. Biochem Pharmacol. 2000;60:1085-1089.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1085-1089
    • Bours, V.1    Bentires-Alj, M.2    Hellin, A.C.3
  • 15
    • 0034668151 scopus 로고    scopus 로고
    • Apoptosis and nuclear factor-kappa B: A tale of association and dissociation
    • Aggarwal BB. Apoptosis and nuclear factor-kappa B: a tale of association and dissociation. Biochem Pharmacol. 2000;60:1033-1039.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1033-1039
    • Aggarwal, B.B.1
  • 16
    • 0033231188 scopus 로고    scopus 로고
    • Modulation of cellular apoptotic potential: Contributions to oncogenesis
    • Stambolic V, Mak TW, Woodgett JR. Modulation of cellular apoptotic potential: contributions to oncogenesis. Oncogene. 1999;18:6094-6103.
    • (1999) Oncogene , vol.18 , pp. 6094-6103
    • Stambolic, V.1    Mak, T.W.2    Woodgett, J.R.3
  • 17
    • 0030884103 scopus 로고    scopus 로고
    • PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
    • Marte BM, Downward J. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem Sci. 1997;22:355-358.
    • (1997) Trends Biochem Sci , vol.22 , pp. 355-358
    • Marte, B.M.1    Downward, J.2
  • 18
    • 0036134017 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor in the treatment of solid tumors
    • Margolin K. Inhibition of vascular endothelial growth factor in the treatment of solid tumors. Curr Oncol Rep. 2002;4:20-28.
    • (2002) Curr Oncol Rep , vol.4 , pp. 20-28
    • Margolin, K.1
  • 19
    • 0029993747 scopus 로고    scopus 로고
    • Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma
    • Brown LF, Tognazzi K, Dvorak HF, Harrist TJ. Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/ vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma. Am J Pathol. 1996;148:1065-1074.
    • (1996) Am J Pathol , vol.148 , pp. 1065-1074
    • Brown, L.F.1    Tognazzi, K.2    Dvorak, H.F.3    Harrist, T.J.4
  • 20
    • 0032080427 scopus 로고    scopus 로고
    • Vascular endothelial growth factor as a marker of tumor endothelium
    • Brekken RA, Huang X, King SW, Thorpe PE. Vascular endothelial growth factor as a marker of tumor endothelium. Cancer Res. 1998;58:1952-1959.
    • (1998) Cancer Res , vol.58 , pp. 1952-1959
    • Brekken, R.A.1    Huang, X.2    King, S.W.3    Thorpe, P.E.4
  • 21
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Takahashi Y, Kitadal Y, Bucana CD, et al. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res. 1995;55:3964-3968.
    • (1995) Cancer Res , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadal, Y.2    Bucana, C.D.3
  • 22
    • 0029857184 scopus 로고    scopus 로고
    • Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer
    • Takahashi Y, Cleary KR, Mai M, et al. Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer. Clin Cancer Res. 1996;2:1679-1684.
    • (1996) Clin Cancer Res , vol.2 , pp. 1679-1684
    • Takahashi, Y.1    Cleary, K.R.2    Mai, M.3
  • 23
    • 0033083962 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies
    • Bellamy WT, Richter L, Frutiger Y, Grogan TM. Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Res. 1999;59:728-733.
    • (1999) Cancer Res , vol.59 , pp. 728-733
    • Bellamy, W.T.1    Richter, L.2    Frutiger, Y.3    Grogan, T.M.4
  • 24
    • 0035166971 scopus 로고    scopus 로고
    • Angiogenic growth factors: Autocrine and paracrine regulation of survival in hematologic malignancies
    • Gabrilove JL. Angiogenic growth factors: autocrine and paracrine regulation of survival in hematologic malignancies. Oncologist. 2001; 6(suppl 5):4-7.
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 5 , pp. 4-7
    • Gabrilove, J.L.1
  • 25
    • 0037015918 scopus 로고    scopus 로고
    • Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors
    • Wang Y, Pennock S, Chen X, Wang Z. Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Sci STKE. 2002;161: L17.
    • (2002) Sci STKE , vol.161
    • Wang, Y.1    Pennock, S.2    Chen, X.3    Wang, Z.4
  • 26
    • 0034859108 scopus 로고    scopus 로고
    • Internalization of the epidermal growth factor receptor: Role in signalling
    • Sorkin A. Internalization of the epidermal growth factor receptor: role in signalling. Biochem Soc Trans. 2001;29:480-484.
    • (2001) Biochem Soc Trans , vol.29 , pp. 480-484
    • Sorkin, A.1
  • 27
    • 0036727023 scopus 로고    scopus 로고
    • Signalling shortcuts: Cell-surface receptors in the nucleus?
    • Wells A, Marti U. Signalling shortcuts: cell-surface receptors in the nucleus? Nat Rev Mol Cell Biol. 2002;3:697-702.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 697-702
    • Wells, A.1    Marti, U.2
  • 28
    • 0033525718 scopus 로고    scopus 로고
    • VEGF induces nuclear translocation of Flk-1/KDR, endothelial nitric oxide synthase, and caveolin-1 in vascular endothelial cells
    • Feng Y, Venema VJ, Venema RC, Tsai N, Caldwell RB. VEGF induces nuclear translocation of Flk-1/KDR, endothelial nitric oxide synthase, and caveolin-1 in vascular endothelial cells. Biochem Biophys Res Commun. 1999;256:192-197.
    • (1999) Biochem Biophys Res Commun , vol.256 , pp. 192-197
    • Feng, Y.1    Venema, V.J.2    Venema, R.C.3    Tsai, N.4    Caldwell, R.B.5
  • 29
    • 0037237791 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol
    • Labrecque L, Royal I, Surprenant DS, Patterson C, Gingras D, Beliveau R. Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. Mol Biol Cell. 2003;14:334-347.
    • (2003) Mol Biol Cell , vol.14 , pp. 334-347
    • Labrecque, L.1    Royal, I.2    Surprenant, D.S.3    Patterson, C.4    Gingras, D.5    Beliveau, R.6
  • 30
    • 0036075106 scopus 로고    scopus 로고
    • Shear stress induces expression of vascular endothelial growth factor receptor Flk-1/KDR through the CT-rich Sp1 binding site
    • Abumiya T, Sasaguri T, Taba Y, Miwa Y, Miyagi M. Shear stress induces expression of vascular endothelial growth factor receptor Flk-1/KDR through the CT-rich Sp1 binding site. Arterioscler Thromb Vasc Biol. 2002;22:907-913.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 907-913
    • Abumiya, T.1    Sasaguri, T.2    Taba, Y.3    Miwa, Y.4    Miyagi, M.5
  • 31
    • 0037047090 scopus 로고    scopus 로고
    • VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells
    • Shay-Salit A, Shushy M, Wolfovitz E, et al. VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells. Proc Natl Acad Sci U S A. 2002;99:9462-9467.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9462-9467
    • Shay-Salit, A.1    Shushy, M.2    Wolfovitz, E.3
  • 32
    • 0036530301 scopus 로고    scopus 로고
    • VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition
    • Dias S, Shmelkov SV, Lam G, Rafii S. VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition. Blood. 2003;99:2532-2540.
    • (2003) Blood , vol.99 , pp. 2532-2540
    • Dias, S.1    Shmelkov, S.V.2    Lam, G.3    Rafii, S.4
  • 33
    • 0036709174 scopus 로고    scopus 로고
    • Nuclear factor-kappa B and cancer: Its role in prevention and therapy
    • 2902
    • Bharti AC, Aggarwal BB. Nuclear factor-kappa B and cancer: its role in prevention and therapy. Biochem Pharmacol. 2902;64:883-888.
    • Biochem Pharmacol , vol.64 , pp. 883-888
    • Bharti, A.C.1    Aggarwal, B.B.2
  • 34
    • 0141993064 scopus 로고    scopus 로고
    • A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia
    • Fiedler W, Mesters R, Tinnenfeld H, et al. A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia. Blood. 2003;102: 2763-2767
    • (2003) Blood , vol.102 , pp. 2763-2767
    • Fiedler, W.1    Mesters, R.2    Tinnenfeld, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.