메뉴 건너뛰기




Volumn 6, Issue 2, 2013, Pages 251-268

NMDA receptor modulators in the treatment of drug addiction

Author keywords

Antagonist; Glutamate; Glycine binding site; N methyl D aspartate receptor; Partial agonist

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ACAMPROSATE; ALCOHOL; AMFEBUTAMONE; CYCLOSERINE; DIAZEPAM; DISULFIRAM; ETHIONAMIDE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALTREXONE; PLACEBO; TRIHEXYPHENIDYL;

EID: 84873650190     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph6020251     Document Type: Review
Times cited : (51)

References (106)
  • 1
    • 0003992201 scopus 로고    scopus 로고
    • United Nations Office on Drugs and Crime. United Nations Pulication: Vienna, Austria
    • United Nations Office on Drugs and Crime. World Drug Report; United Nations Pulication: Vienna, Austria, 2009.
    • (2009) World Drug Report
  • 2
    • 77957904093 scopus 로고    scopus 로고
    • Results from the 2009 National Survey on Drug Use and Health, Volume 1
    • U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services: Rockville, MD, USA
    • Results from the 2009 National Survey on Drug Use and Health, Volume 1. Summary of National Findings; U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services: Rockville, MD, USA, 2010.
    • (2010) Summary of National Findings
  • 3
    • 80053131013 scopus 로고    scopus 로고
    • New medications for drug addiction hiding in glutamatergic neuroplasticity
    • Kalivas, P.W.; Volkow, N.D. New medications for drug addiction hiding in glutamatergic neuroplasticity. Mol. Psychiatry 2011, 16, 974-986.
    • (2011) Mol. Psychiatry , vol.16 , pp. 974-986
    • Kalivas, P.W.1    Volkow, N.D.2
  • 4
    • 84870489658 scopus 로고    scopus 로고
    • American Psychiatric Association. In 4th Ed.; American Psychiatric Press: Washington DC, USA
    • American Psychiatric Association. In Diagnostic and Statistical Manual of Mental Disorders, 4th Ed.; American Psychiatric Press: Washington DC, USA, 2002.
    • (2002) Diagnostic and Statistical Manual of Mental Disorders
  • 6
    • 0032228998 scopus 로고    scopus 로고
    • Age of onset of drug use and its association with DSM-IV drug abuse and dependence: Results from the National Longitudinal Alcohol Epidemiologic Survey
    • Grant, B.F.; Dawson, D.A. Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. J. Subst. Abuse 1998, 10, 163-173.
    • (1998) J. Subst. Abuse , vol.10 , pp. 163-173
    • Grant, B.F.1    Dawson, D.A.2
  • 7
    • 2942522762 scopus 로고    scopus 로고
    • The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002
    • Grant, B.F.; Dawson, D.A.; Stinson, F.S.; Chou, S.P.; Dufour, M.C.; Pickering, R.P. The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002. Drug Alcohol Depend. 2004, 74, 223-234.
    • (2004) Drug Alcohol Depend. , vol.74 , pp. 223-234
    • Grant, B.F.1    Dawson, D.A.2    Stinson, F.S.3    Chou, S.P.4    Dufour, M.C.5    Pickering, R.P.6
  • 8
    • 0034834576 scopus 로고    scopus 로고
    • Molecular neurobiology of addiction
    • Nestler, E.J. Molecular neurobiology of addiction. Am. J. Addict. 2001, 10, 201-217.
    • (2001) Am. J. Addict. , vol.10 , pp. 201-217
    • Nestler, E.J.1
  • 9
    • 84855534956 scopus 로고    scopus 로고
    • Glutamatergic medications for the treatment of drug and behavioral addictions
    • Olive, M.F.; Cleva, R.M.; Kalivas, P.W.; Malcolm, R.J. Glutamatergic medications for the treatment of drug and behavioral addictions. Pharmacol. Biochem. Behav. 2012, 100, 801-810.
    • (2012) Pharmacol. Biochem. Behav. , vol.100 , pp. 801-810
    • Olive, M.F.1    Cleva, R.M.2    Kalivas, P.W.3    Malcolm, R.J.4
  • 11
    • 79551635298 scopus 로고    scopus 로고
    • Prevalence of the addictions: A problem of the majority or the minority?
    • Sussman, S.; Lisha, N.; Griffiths, M. Prevalence of the addictions: a problem of the majority or the minority? Eval. Health Prof. 2011, 34, 3-56.
    • (2011) Eval. Health Prof. , vol.34 , pp. 3-56
    • Sussman, S.1    Lisha, N.2    Griffiths, M.3
  • 13
    • 36849072543 scopus 로고    scopus 로고
    • Glutamatergic substrates of drug addiction and alcoholism
    • Gass, J.T.; Olive, M.F. Glutamatergic substrates of drug addiction and alcoholism. Biochem. Pharmacol. 2008, 75, 218-265.
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 218-265
    • Gass, J.T.1    Olive, M.F.2
  • 14
    • 84873655127 scopus 로고    scopus 로고
    • Medications for the treatment of cocaine addiction: Focus on glutamatergic compounds
    • In Fang, X.C.; Yue, L. Eds.; Nova Biomedical: Hauppauge, NY, USA
    • Nemirovsky, N.E.; Olive, M.F. Medications for the treatment of cocaine addiction: focus on glutamatergic compounds In Cocaine Abuse: Pharmacology, Treatment and Relapse Prevention; Fang, X.C.; Yue, L. Eds.; Nova Biomedical: Hauppauge, NY, USA, 2012; pp 115-129.
    • (2012) Cocaine Abuse: Pharmacology, Treatment and Relapse Prevention , pp. 115-129
    • Nemirovsky, N.E.1    Olive, M.F.2
  • 15
    • 67651083577 scopus 로고    scopus 로고
    • The glutamate homeostasis hypothesis of addiction
    • Kalivas, P.W. The glutamate homeostasis hypothesis of addiction. Nat. Rev. Neurosci. 2009, 10, 561-572.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 561-572
    • Kalivas, P.W.1
  • 16
    • 78649650201 scopus 로고    scopus 로고
    • Glutamate receptors in extinction and extinction-based therapies for psychiatric illness
    • Myers, K.M.; Carlezon, W.A., Jr.; Davis, M. Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. Neuropsychopharmacology 2011, 36, 274-293.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 274-293
    • Myers, K.M.1    Carlezon Jr., W.A.2    Davis, M.3
  • 17
    • 0027234701 scopus 로고
    • The molecular biology of mammalian glutamate receptor channels
    • Seeburg, P.H. The molecular biology of mammalian glutamate receptor channels. Trends Neurosci. 1993, 16, 359-365.
    • (1993) Trends Neurosci. , vol.16 , pp. 359-365
    • Seeburg, P.H.1
  • 18
    • 0033047334 scopus 로고    scopus 로고
    • Expression mechanisms underlying NMDA receptor-dependent long-term potentiation
    • Nicoll, R.A.; Malenka, R.C. Expression mechanisms underlying NMDA receptor-dependent long-term potentiation. Ann. N. Y. Acad. Sci. 1999, 868, 515-525.
    • (1999) Ann. N. Y. Acad. Sci. , vol.868 , pp. 515-525
    • Nicoll, R.A.1    Malenka, R.C.2
  • 20
    • 34249099711 scopus 로고    scopus 로고
    • NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
    • Lau, C.G.; Zukin, R.S. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci. 2007, 8, 413-426.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 413-426
    • Lau, C.G.1    Zukin, R.S.2
  • 21
    • 36749012387 scopus 로고    scopus 로고
    • The NMDA receptor/ion channel complex: A drug target for modulating synaptic plasticity and excitotoxicity
    • Albensi, B.C. The NMDA receptor/ion channel complex: A drug target for modulating synaptic plasticity and excitotoxicity. Curr. Pharm. Des. 2007, 13, 3185-3194.
    • (2007) Curr. Pharm. Des. , vol.13 , pp. 3185-3194
    • Albensi, B.C.1
  • 22
    • 0037301661 scopus 로고    scopus 로고
    • The Yin and Yang of NMDA receptor signalling
    • Hardingham, G.E.; Bading, H. The Yin and Yang of NMDA receptor signalling. Trends Neurosci. 2003, 26, 81-89.
    • (2003) Trends Neurosci. , vol.26 , pp. 81-89
    • Hardingham, G.E.1    Bading, H.2
  • 24
    • 0142031078 scopus 로고    scopus 로고
    • Therapeutic N-methyl-D-aspartate receptor antagonists: Will reality meet expectation?
    • Smith, P.F. Therapeutic N-methyl-D-aspartate receptor antagonists: will reality meet expectation? Curr. Opin. Investig. Drugs 2003, 4, 826-832.
    • (2003) Curr. Opin. Investig. Drugs , vol.4 , pp. 826-832
    • Smith, P.F.1
  • 25
    • 8844263762 scopus 로고    scopus 로고
    • Positive and negative allosteric modulation of metabotropic glutamate receptors: Emerging therapeutic potential
    • Kew, J.N.C. Positive and negative allosteric modulation of metabotropic glutamate receptors: emerging therapeutic potential. Pharmacol. Ther. 2004, 104, 233-244.
    • (2004) Pharmacol. Ther. , vol.104 , pp. 233-244
    • Kew, J.N.C.1
  • 26
    • 33745034018 scopus 로고    scopus 로고
    • The chemical biology of clincially tolerated NMDA receptor antagonists
    • Chen, H.S.; Lipton, S.A. The chemical biology of clincially tolerated NMDA receptor antagonists. J. Neurochem. 2006, 97, 1611-1626.
    • (2006) J. Neurochem. , vol.97 , pp. 1611-1626
    • Chen, H.S.1    Lipton, S.A.2
  • 27
    • 13544268511 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor subtypes: Multiple roles in excitotoxicity and neurological disease
    • Waxman, E.A.; Lynch, D.R. N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease. Neuroscientist 2005, 11, 37-49.
    • (2005) Neuroscientist , vol.11 , pp. 37-49
    • Waxman, E.A.1    Lynch, D.R.2
  • 29
    • 0141502156 scopus 로고    scopus 로고
    • Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation
    • Law, A.J.; Weickert, C.S.; Webster, M.J.; Herman, M.M.; Kleinman, J.E.; Harrison, P.J. Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation. Eur. J. Neurosci. 2003, 18, 1197-1205.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1197-1205
    • Law, A.J.1    Weickert, C.S.2    Webster, M.J.3    Herman, M.M.4    Kleinman, J.E.5    Harrison, P.J.6
  • 30
    • 0035007671 scopus 로고    scopus 로고
    • In and out of the K-hole: A comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users
    • Curran, H.V.; Monaghan, L. In and out of the K-hole: a comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users. Addiction 2001, 96, 749-760.
    • (2001) Addiction , vol.96 , pp. 749-760
    • Curran, H.V.1    Monaghan, L.2
  • 31
    • 70350412253 scopus 로고    scopus 로고
    • Memantine binding to a superficial site on NMDA receptors contributes to partial trapping
    • Kotermanski, S.E.; Wood, J.T.; Johnson, J.W. Memantine binding to a superficial site on NMDA receptors contributes to partial trapping. J. Physiol. 2009, 587, 4589-4604.
    • (2009) J. Physiol. , vol.587 , pp. 4589-4604
    • Kotermanski, S.E.1    Wood, J.T.2    Johnson, J.W.3
  • 32
    • 0031868767 scopus 로고    scopus 로고
    • Mechanism of action of acamprosate. Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain
    • Naassila, M.; Hammoumi, S.; Legrand, E.; Durbin, P.; Daoust, M. Mechanism of action of acamprosate. Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain. Alcohol. Clin. Exp. Res. 1998, 22, 802-809.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 802-809
    • Naassila, M.1    Hammoumi, S.2    Legrand, E.3    Durbin, P.4    Daoust, M.5
  • 33
    • 0024502818 scopus 로고
    • D-cycloserine: A ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics
    • Hood, W.F.; Compton, R.P.; Monahan, J.B. D-cycloserine: a ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics. Neurosci. Lett. 1989, 98, 91-95.
    • (1989) Neurosci. Lett. , vol.98 , pp. 91-95
    • Hood, W.F.1    Compton, R.P.2    Monahan, J.B.3
  • 34
    • 0030766528 scopus 로고    scopus 로고
    • Molecular and cellular basis of addiction
    • Nestler, E.J.; Aghajanian, G.K. Molecular and cellular basis of addiction. Science 1997, 278, 58-63.
    • (1997) Science , vol.278 , pp. 58-63
    • Nestler, E.J.1    Aghajanian, G.K.2
  • 35
    • 0028979718 scopus 로고
    • N-methyl-D-aspartic acid-receptor antagonists block morphineinduced conditioned place preference in rats
    • Tzschentke, T.M.; Schmidt, W.J. N-methyl-D-aspartic acid-receptor antagonists block morphineinduced conditioned place preference in rats. Neurosci. Lett. 1995, 193, 37-40.
    • (1995) Neurosci. Lett. , vol.193 , pp. 37-40
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 36
    • 0027135373 scopus 로고
    • Blockade of the acquisition of cocaine self-administration by the NMDA antagonist MK-801 (dizocilpine)
    • Schenk, S.; Valadez, A.; Worley, C.M.; McNamara, C. Blockade of the acquisition of cocaine self-administration by the NMDA antagonist MK-801 (dizocilpine). Behav. Pharmacol. 1993, 4, 652-659.
    • (1993) Behav. Pharmacol. , vol.4 , pp. 652-659
    • Schenk, S.1    Valadez, A.2    Worley, C.M.3    McNamara, C.4
  • 37
    • 47749150634 scopus 로고    scopus 로고
    • A systematic review of off-label uses of memantine for psychiatric disorders
    • Zdanys, K.; Tampi, R.R. A systematic review of off-label uses of memantine for psychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32, 1362-1374.
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.32 , pp. 1362-1374
    • Zdanys, K.1    Tampi, R.R.2
  • 38
    • 33747423612 scopus 로고    scopus 로고
    • Memantine: A review of its use in alzheimer-s disease
    • Robinson, D.M.; Keating, G.M. Memantine: A review of its use in alzheimer-s disease. Drugs 2006, 66, 1515-1534.
    • (2006) Drugs , vol.66 , pp. 1515-1534
    • Robinson, D.M.1    Keating, G.M.2
  • 39
    • 0032812808 scopus 로고    scopus 로고
    • Low-affinity NMDA receptor channel blockers inhibit acquisition of intravenous morphine self-administration in naive mice
    • Semenova, S.; Danysz, W.; Bespalov, A. Low-affinity NMDA receptor channel blockers inhibit acquisition of intravenous morphine self-administration in naive mice. Eur. J. Pharmacol. 1999, 378, 1-8.
    • (1999) Eur. J. Pharmacol. , vol.378 , pp. 1-8
    • Semenova, S.1    Danysz, W.2    Bespalov, A.3
  • 40
    • 0344849494 scopus 로고    scopus 로고
    • Site-specific NMDA receptor antagonists produce differential effects on cocaine self-administration in rats
    • Hyytia, P.; Backstrom, P.; Liljequist, S. Site-specific NMDA receptor antagonists produce differential effects on cocaine self-administration in rats. Eur. J. Pharmacol. 1999, 378, 9-16.
    • (1999) Eur. J. Pharmacol. , vol.378 , pp. 9-16
    • Hyytia, P.1    Backstrom, P.2    Liljequist, S.3
  • 41
    • 13244299114 scopus 로고    scopus 로고
    • Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice
    • Blokhina, E.A.; Kashkin, V.A.; Zvartau, E.E.; Danysz, W.; Bespalov, A.Y. Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice. Eur. Neuropsychopharmacol. 2005, 15, 219-225.
    • (2005) Eur. Neuropsychopharmacol. , vol.15 , pp. 219-225
    • Blokhina, E.A.1    Kashkin, V.A.2    Zvartau, E.E.3    Danysz, W.4    Bespalov, A.Y.5
  • 42
    • 0030942167 scopus 로고    scopus 로고
    • Inhibition of reinforcing effects of morphine and motivational aspects of naloxone-precipitated opioid withdrawal by N-methyl-D-aspartate receptor antagonist, memantine
    • Popik, P.; Danysz, W. Inhibition of reinforcing effects of morphine and motivational aspects of naloxone-precipitated opioid withdrawal by N-methyl-D-aspartate receptor antagonist, memantine. J. Pharmacol. Exp. Ther. 1997, 280, 854-865.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 854-865
    • Popik, P.1    Danysz, W.2
  • 43
    • 0343962290 scopus 로고    scopus 로고
    • Memantine and ACPC affect conditioned place preference induced by cocaine in rats
    • Kotlinska, J.; Biala, G. Memantine and ACPC affect conditioned place preference induced by cocaine in rats. Pol. J. Pharmacol. 2000, 52, 179-185.
    • (2000) Pol. J. Pharmacol. , vol.52 , pp. 179-185
    • Kotlinska, J.1    Biala, G.2
  • 44
    • 0038348596 scopus 로고    scopus 로고
    • Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice
    • Popik, P.; Wrobel, M.; Rygula, R.; Bisaga, A.; Bespalov, A.Y. Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice. Behav. Pharmacol. 2003, 14, 237-244.
    • (2003) Behav. Pharmacol. , vol.14 , pp. 237-244
    • Popik, P.1    Wrobel, M.2    Rygula, R.3    Bisaga, A.4    Bespalov, A.Y.5
  • 46
    • 11444265610 scopus 로고    scopus 로고
    • NMDA glutamate but not dopamine antagonists blocks drug-induced reinstatement of morphine place preference
    • Ribeiro Do Couto, B.; Aguilar, M.A.; Manzanedo, C.; Rodriguez-Arias, M.; Minarro, J. NMDA glutamate but not dopamine antagonists blocks drug-induced reinstatement of morphine place preference. Brain Res. Bull. 2005, 64, 493-503.
    • (2005) Brain Res. Bull. , vol.64 , pp. 493-503
    • Ribeiro Do Couto, B.1    Aguilar, M.A.2    Manzanedo, C.3    Rodriguez-Arias, M.4    Minarro, J.5
  • 47
    • 32844465631 scopus 로고    scopus 로고
    • Reinstatement of morphine-conditioned reward is blocked by memantine
    • Popik, P.; Wrobel, M.; Bisaga, A. Reinstatement of morphine-conditioned reward is blocked by memantine. Neuropsychopharmacology 2006, 31, 160-170.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 160-170
    • Popik, P.1    Wrobel, M.2    Bisaga, A.3
  • 50
    • 0033998839 scopus 로고    scopus 로고
    • Effects of N-methyl-D-aspartate receptor antagonists on reinstatement of cocaine-seeking behavior by priming injections of cocaine or exposures to cocaine-associated cues in rats
    • Bespalov, A.Y.; Zvartau, E.E.; Balster, R.L.; Beardsley, P.M. Effects of N-methyl-D-aspartate receptor antagonists on reinstatement of cocaine-seeking behavior by priming injections of cocaine or exposures to cocaine-associated cues in rats. Behav. Pharmacol. 2000, 11, 37-44.
    • (2000) Behav. Pharmacol. , vol.11 , pp. 37-44
    • Bespalov, A.Y.1    Zvartau, E.E.2    Balster, R.L.3    Beardsley, P.M.4
  • 51
    • 1542284248 scopus 로고    scopus 로고
    • Acute effects of memantine in combination with alcohol in moderate drinkers
    • Bisaga, A.; Evans, S.M. Acute effects of memantine in combination with alcohol in moderate drinkers. Psychopharmacology 2004, 16-24.
    • (2004) Psychopharmacology , pp. 16-24
    • Bisaga, A.1    Evans, S.M.2
  • 53
    • 34249908640 scopus 로고    scopus 로고
    • Memantine for alcohol dependence: An openlabel pilot study Addict
    • Arias, A.J.; Feinn, R.; Covault, J.; Kranzler, H.R. Memantine for alcohol dependence: an openlabel pilot study Addict. Disord. Treat. 2007, 77-83.
    • (2007) Disord. Treat. , pp. 77-83
    • Arias, A.J.1    Feinn, R.2    Covault, J.3    Kranzler, H.R.4
  • 54
    • 34247120166 scopus 로고    scopus 로고
    • A pilot double-blind treatment trial of memantine for alcohol dependence
    • Evans, S.M.; Levin, F.R.; Brooks, D.J.; Garawi, F. A pilot double-blind treatment trial of memantine for alcohol dependence. Alcohol. Clin. Exp. Res. 2007, 31, 775-782.
    • (2007) Alcohol. Clin. Exp. Res. , vol.31 , pp. 775-782
    • Evans, S.M.1    Levin, F.R.2    Brooks, D.J.3    Garawi, F.4
  • 55
    • 0036449515 scopus 로고    scopus 로고
    • Effects of the NMDA antagonist memantine on human methamphetamine discrimination
    • Hart, C.L.; Haney, M.; Foltin, R.W.; Fischman, M.W. Effects of the NMDA antagonist memantine on human methamphetamine discrimination. Psychopharmacology 2002, 164, 376-384.
    • (2002) Psychopharmacology , vol.164 , pp. 376-384
    • Hart, C.L.1    Haney, M.2    Foltin, R.W.3    Fischman, M.W.4
  • 56
    • 77955607962 scopus 로고    scopus 로고
    • Acamprosate: How, where, and for whom does it work? Mechanism of action, treatment targets, and individualized therapy
    • Kiefer, F.; Mann, K. Acamprosate: how, where, and for whom does it work? Mechanism of action, treatment targets, and individualized therapy. Curr. Pharm. Des. 2010, 16, 2098-2102.
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 2098-2102
    • Kiefer, F.1    Mann, K.2
  • 58
    • 0030000009 scopus 로고    scopus 로고
    • Acamprosate (calcium acetylhomotaurinate) enhances the N-methyl-D-aspartate component of excitatory neurotransmission in rat hippocampal CA1 neurons in vitro
    • Madamba, S.G.; Schweitzer, P.; Zieglgänsberger, W.; Siggins, G.R. Acamprosate (calcium acetylhomotaurinate) enhances the N-methyl-D-aspartate component of excitatory neurotransmission in rat hippocampal CA1 neurons in vitro. Alcohol. Clin. Exp. Res. 1996, 20, 651-658.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20 , pp. 651-658
    • Madamba, S.G.1    Schweitzer, P.2    Zieglgänsberger, W.3    Siggins, G.R.4
  • 59
    • 0031885253 scopus 로고    scopus 로고
    • Acamprosate enhances N-methyl-D-apartate receptor-mediated neurotransmission but inhibits presynaptic GABAB receptors in nucleus accumbens neurons
    • Berton, F.; Francesconi, W.G.; Madamba, S.G.; Zieglgänsberger, W.; Siggins, G.R. Acamprosate enhances N-methyl-D-apartate receptor-mediated neurotransmission but inhibits presynaptic GABAB receptors in nucleus accumbens neurons. Alcohol. Clin. Exp. Res. 1998, 22, 183-191.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 183-191
    • Berton, F.1    Francesconi, W.G.2    Madamba, S.G.3    Zieglgänsberger, W.4    Siggins, G.R.5
  • 60
    • 0027402518 scopus 로고
    • Acamprosate (calciumacetylhomotaurinate) decreases postsynaptic potentials in the rat neocortex: Possible involvement of excitatory amino acid receptors
    • Zeise, M.L.; Kasparov, S.; Capogna, M.; Zieglgänsberger, W. Acamprosate (calciumacetylhomotaurinate) decreases postsynaptic potentials in the rat neocortex: possible involvement of excitatory amino acid receptors. Eur. J. Pharmacol. 1993, 231, 47-52.
    • (1993) Eur. J. Pharmacol. , vol.231 , pp. 47-52
    • Zeise, M.L.1    Kasparov, S.2    Capogna, M.3    Zieglgänsberger, W.4
  • 61
    • 0025035137 scopus 로고
    • Calcium diacetylhomotaurinate (CA-AOTA) decreases the action of excitatory amino acids in the rat neocortex in vitro
    • Zeise, M.L.; Kasparow, S.; Capogna, M.; Zieglgänsberger, W. Calcium diacetylhomotaurinate (CA-AOTA) decreases the action of excitatory amino acids in the rat neocortex in vitro. Prog. Clin. Biol. Res. 1990, 351, 237-242.
    • (1990) Prog. Clin. Biol. Res. , vol.351 , pp. 237-242
    • Zeise, M.L.1    Kasparow, S.2    Capogna, M.3    Zieglgänsberger, W.4
  • 62
    • 0035001893 scopus 로고    scopus 로고
    • The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801
    • Rammes, G.; Mahal, B.; Putzke, J.; Parsons, C.; Spielmanns, P.; Pestel, E.; Spanagel, R.; Zieglgansberger, W.; Schadrack, J. The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. Neuropharmacology 2001, 40, 749-760.
    • (2001) Neuropharmacology , vol.40 , pp. 749-760
    • Rammes, G.1    Mahal, B.2    Putzke, J.3    Parsons, C.4    Spielmanns, P.5    Pestel, E.6    Spanagel, R.7    Zieglgansberger, W.8    Schadrack, J.9
  • 63
    • 0033626509 scopus 로고    scopus 로고
    • Acamprosate inhibits Ca2+ influx mediated by NMDA receptors and voltage-sensitive Ca2+ channels in cultured rat mesencephalic neurones
    • Allgaier, C.; Franke, H.; Sobottka, H.; Scheibler, P. Acamprosate inhibits Ca2+ influx mediated by NMDA receptors and voltage-sensitive Ca2+ channels in cultured rat mesencephalic neurones. Naunyn-Schmied. Arch. Pharmacol. 2000, 362, 440-443.
    • (2000) Naunyn-Schmied. Arch. Pharmacol. , vol.362 , pp. 440-443
    • Allgaier, C.1    Franke, H.2    Sobottka, H.3    Scheibler, P.4
  • 64
    • 0034646855 scopus 로고    scopus 로고
    • Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons
    • Popp, R.L.; Lovinger, D.M. Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur. J. Pharmacol. 2000, 394, 221-231.
    • (2000) Eur. J. Pharmacol. , vol.394 , pp. 221-231
    • Popp, R.L.1    Lovinger, D.M.2
  • 65
    • 23044516183 scopus 로고    scopus 로고
    • Neuroprotective and abstinence-promoting effects of acamprosate: Elucidating the mechanism of action
    • De Witte, P.; Littleton, J.; Parot, P.; Koob, G. Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action. CNS Drugs 2005, 19, 517-537.
    • (2005) CNS Drugs , vol.19 , pp. 517-537
    • de Witte, P.1    Littleton, J.2    Parot, P.3    Koob, G.4
  • 66
    • 0031813519 scopus 로고    scopus 로고
    • Mechanism of action of acamprosate. Part II. Ethanol dependence modifies effects of acamprosate on NMDA receptor binding in membranes from rat cerebral cortex
    • Al Qatari, M.; Bouchenafa, O.; Littleton, J. Mechanism of action of acamprosate. Part II. Ethanol dependence modifies effects of acamprosate on NMDA receptor binding in membranes from rat cerebral cortex. Alcohol. Clin. Exp. Res. 1998, 22, 810-814.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 810-814
    • Al Qatari, M.1    Bouchenafa, O.2    Littleton, J.3
  • 69
    • 0037275407 scopus 로고    scopus 로고
    • The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine
    • Mcgeehan, A.J.; Olive, M.F. The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine. Br. J. Pharmacol. 2003, 138, 9-12.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 9-12
    • McGeehan, A.J.1    Olive, M.F.2
  • 70
    • 33747472833 scopus 로고    scopus 로고
    • Attenuation of cocaine-induced reinstatement of cocaine conditioned place preference by acamprosate
    • Mcgeehan, A.J.; Olive, M.F. Attenuation of cocaine-induced reinstatement of cocaine conditioned place preference by acamprosate. Behav. Pharmacol. 2006, 17, 363-367.
    • (2006) Behav. Pharmacol. , vol.17 , pp. 363-367
    • McGeehan, A.J.1    Olive, M.F.2
  • 72
    • 0031697417 scopus 로고    scopus 로고
    • Acamprosate suppresses the expression of morphine-induced sensitization in rats but does not affect heroin self-administration or relapse induced by heroin or stress
    • Spanagel, R.; Sillaber, I.; Zieglgansberger, W.; Corrigall, W.A.; Stewart, J.; Shaham, Y. Acamprosate suppresses the expression of morphine-induced sensitization in rats but does not affect heroin self-administration or relapse induced by heroin or stress. Psychopharmacology 1998, 139, 391-401.
    • (1998) Psychopharmacology , vol.139 , pp. 391-401
    • Spanagel, R.1    Sillaber, I.2    Zieglgansberger, W.3    Corrigall, W.A.4    Stewart, J.5    Shaham, Y.6
  • 73
    • 74349102754 scopus 로고    scopus 로고
    • The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence
    • Mason, B.J.; Heyser, C.J. The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence. Expert Opin. Drug Saf. 2010, 177-188.
    • (2010) Expert Opin. Drug Saf. , pp. 177-188
    • Mason, B.J.1    Heyser, C.J.2
  • 74
    • 77955607962 scopus 로고    scopus 로고
    • Acamprosate: How, Where, and for Whom does it work? Mechanism of Action, Treatment Targets and Individualized Therapy
    • Kiefer, F.; Mann, K. Acamprosate: How, Where, and for Whom does it work? Mechanism of Action, Treatment Targets and Individualized Therapy. Current Pharmaceut. Des. 2010, 2098-2102.
    • (2010) Current Pharmaceut. Des. , pp. 2098-2102
    • Kiefer, F.1    Mann, K.2
  • 76
    • 74349102754 scopus 로고    scopus 로고
    • The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence
    • Mason, B.J.; Heyser, C.J. The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence. Expert Opin. Drug Saf. 2010, 9, 177-188.
    • (2010) Expert Opin. Drug Saf. , vol.9 , pp. 177-188
    • Mason, B.J.1    Heyser, C.J.2
  • 77
    • 78650910189 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled pilot trial of acamprosate for the treatment of cocaine dependence
    • Kampman, K.M.; Dackis, C.; Pettinati, H.M.; Lynch, K.G.; Sparkman, T.; O'Brien, C.P. A double-blind, placebo-controlled pilot trial of acamprosate for the treatment of cocaine dependence. Addict. Behav. 2011, 36, 217-221.
    • (2011) Addict. Behav. , vol.36 , pp. 217-221
    • Kampman, K.M.1    Dackis, C.2    Pettinati, H.M.3    Lynch, K.G.4    Sparkman, T.5    O'Brien, C.P.6
  • 78
    • 84861043513 scopus 로고    scopus 로고
    • D-cycloserine effects on extinction of conditioned responses to drug-related cues
    • Myers, K.M.; Carlezon, W.A.J. D-cycloserine effects on extinction of conditioned responses to drug-related cues. Biol. Psychiatry 2012, 71, 947-955.
    • (2012) Biol. Psychiatry , vol.71 , pp. 947-955
    • Myers, K.M.1    Carlezon, W.A.J.2
  • 79
    • 0034898096 scopus 로고    scopus 로고
    • Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine
    • Sheinin, A.; Shavit, S.; Benveniste, M. Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine. Neuropharmacology 2001, 41, 151-158.
    • (2001) Neuropharmacology , vol.41 , pp. 151-158
    • Sheinin, A.1    Shavit, S.2    Benveniste, M.3
  • 80
    • 33747083749 scopus 로고    scopus 로고
    • Effects of D-cycloserine on extinction: Translation from preclinical to clinical work
    • Davis, M.; Ressler, K.; Rothbaum, B.O.; Richardson, R. Effects of D-cycloserine on extinction: translation from preclinical to clinical work. Biol. Psychiatry 2006, 60, 369-375.
    • (2006) Biol. Psychiatry , vol.60 , pp. 369-375
    • Davis, M.1    Ressler, K.2    Rothbaum, B.O.3    Richardson, R.4
  • 81
    • 33745861725 scopus 로고    scopus 로고
    • d-Cycloserine facilitates extinction of a cocaine-induced conditioned place preference
    • Botreau, F.; Paolone, G.; Stewart, J. d-Cycloserine facilitates extinction of a cocaine-induced conditioned place preference. Behav. Brain Res. 2006, 172, 173-178.
    • (2006) Behav. Brain Res. , vol.172 , pp. 173-178
    • Botreau, F.1    Paolone, G.2    Stewart, J.3
  • 82
    • 61349103638 scopus 로고    scopus 로고
    • D-Cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57BL/c mice
    • Thanos, P.K.; Bermeo, C.; Wang, G.J.; Volkow, N.D. D-Cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57BL/c mice. Behav. Brain Res. 2009, 199, 345-349.
    • (2009) Behav. Brain Res. , vol.199 , pp. 345-349
    • Thanos, P.K.1    Bermeo, C.2    Wang, G.J.3    Volkow, N.D.4
  • 83
    • 79960023576 scopus 로고    scopus 로고
    • D-cycloserine facilitates extinction of cocaine self-administration in rats
    • Thanos, P.K.; Bermeo, C.; Wang, G.J.; Volkow, N.D. D-cycloserine facilitates extinction of cocaine self-administration in rats. Synapse 2011, 65, 938-944.
    • (2011) Synapse , vol.65 , pp. 938-944
    • Thanos, P.K.1    Bermeo, C.2    Wang, G.J.3    Volkow, N.D.4
  • 85
    • 77955363553 scopus 로고    scopus 로고
    • D-cycloserine reduces the context specificity of Pavlovian extinction of cocaine cues through actions in the nucleus accumbens
    • Torregrossa, M.M.; Sanchez, H.; Taylor, J.R. D-cycloserine reduces the context specificity of Pavlovian extinction of cocaine cues through actions in the nucleus accumbens. J. Neurosci. 2010, 30, 10526-10533.
    • (2010) J. Neurosci. , vol.30 , pp. 10526-10533
    • Torregrossa, M.M.1    Sanchez, H.2    Taylor, J.R.3
  • 86
    • 61949084079 scopus 로고    scopus 로고
    • D-cycloserine potentiates the reconsolidation of cocaine-associated memories
    • Lee, J.L.; Gardner, R.J.; Butler, V.J.; Everitt, B.J. D-cycloserine potentiates the reconsolidation of cocaine-associated memories. Learn. Mem. 2009, 16, 82-85.
    • (2009) Learn. Mem. , vol.16 , pp. 82-85
    • Lee, J.L.1    Gardner, R.J.2    Butler, V.J.3    Everitt, B.J.4
  • 87
    • 33846478897 scopus 로고    scopus 로고
    • Mechanisms of fear extinction
    • Myers, K.M.; Davis, M. Mechanisms of fear extinction. Mol. Psychiatry 2007, 12, 120-150.
    • (2007) Mol. Psychiatry , vol.12 , pp. 120-150
    • Myers, K.M.1    Davis, M.2
  • 89
    • 85047681206 scopus 로고    scopus 로고
    • Applying laboratory research: Drug anticipation and the treatment of drug addiction
    • Siegel, S.; Ramos, B.M. Applying laboratory research: drug anticipation and the treatment of drug addiction. Exp. Clin. Psychopharmacol. 2002, 10, 162-183.
    • (2002) Exp. Clin. Psychopharmacol. , vol.10 , pp. 162-183
    • Siegel, S.1    Ramos, B.M.2
  • 91
    • 84862680157 scopus 로고    scopus 로고
    • Cue exposure and response prevention with heavy smokers: A laboratory-based randomised placebo-controlled trial examining the effects of D-cycloserine on cue reactivity and attentional bias
    • Kamboj, S.K.; Joye, A.; Das, R.K.; Gibson, A.J.; Morgan, C.J.; Curran, H.V. Cue exposure and response prevention with heavy smokers: a laboratory-based randomised placebo-controlled trial examining the effects of D-cycloserine on cue reactivity and attentional bias. Psychopharmacology 2012, 221, 273-284.
    • (2012) Psychopharmacology , vol.221 , pp. 273-284
    • Kamboj, S.K.1    Joye, A.2    Das, R.K.3    Gibson, A.J.4    Morgan, C.J.5    Curran, H.V.6
  • 95
    • 84857536606 scopus 로고    scopus 로고
    • Effects of D-cycloserine on craving to alcohol cues in problem drinkers: Preliminary findings
    • Hofmann, S.G.; Huweler, R.; MacKillop, J.; Kantak, K.M. Effects of D-cycloserine on craving to alcohol cues in problem drinkers: preliminary findings. Am. J. Drug Alcohol Abuse 2012, 38, 101-107.
    • (2012) Am. J. Drug Alcohol Abuse , vol.38 , pp. 101-107
    • Hofmann, S.G.1    Huweler, R.2    McKillop, J.3    Kantak, K.M.4
  • 96
    • 64549086850 scopus 로고    scopus 로고
    • Effects of D-cycloserine on extinction and reconditioning of ethanol-seeking behavior in mice
    • Groblewski, P.A.; Lattal, K.M.; Cunningham, C.L. Effects of D-cycloserine on extinction and reconditioning of ethanol-seeking behavior in mice. Alcohol. Clin. Exp. Res. 2009, 33, 772-782.
    • (2009) Alcohol. Clin. Exp. Res. , vol.33 , pp. 772-782
    • Groblewski, P.A.1    Lattal, K.M.2    Cunningham, C.L.3
  • 97
    • 84868206229 scopus 로고    scopus 로고
    • Maintaining clinical relevance: Considerations for the future of research into d-cycloserine and cue exposure therapy for addiction
    • Das, R.K.; Kamboj, S.K. Maintaining clinical relevance: considerations for the future of research into d-cycloserine and cue exposure therapy for addiction. Biol. Psychiatry 2012, 72, e29-30.
    • (2012) Biol. Psychiatry , vol.72
    • Das, R.K.1    Kamboj, S.K.2
  • 98
    • 62749122197 scopus 로고    scopus 로고
    • Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory
    • Gass, J.T.; Olive, M.F. Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory. Biol. Psychiatry 2009, 65, 717-720.
    • (2009) Biol. Psychiatry , vol.65 , pp. 717-720
    • Gass, J.T.1    Olive, M.F.2
  • 101
    • 79951516164 scopus 로고    scopus 로고
    • Loss of object recognition memory produced by exteded access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5
    • Reichel, C.M.; Schwendt, M.; McGinty, J.F.; Olive, M.F.; See, R.E. Loss of object recognition memory produced by exteded access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5. Neuropsychopharmacology 2011, 36, 782-792.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 782-792
    • Reichel, C.M.1    Schwendt, M.2    McGinty, J.F.3    Olive, M.F.4    See, R.E.5
  • 102
    • 77949516412 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Physiology, pharmacology, and disease
    • Niswender, C.M.; Conn, P.J. Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu. Rev. Pharmacol. Toxicol. 2010, 50, 295-322.
    • (2010) Annu. Rev. Pharmacol. Toxicol. , vol.50 , pp. 295-322
    • Niswender, C.M.1    Conn, P.J.2
  • 103
    • 70449675086 scopus 로고    scopus 로고
    • The promiscuous mGlu5 receptor-a range of partners for therapeutic possibilities?
    • Bird, M.K.; Lawrence, A.J. The promiscuous mGlu5 receptor-a range of partners for therapeutic possibilities? Trends Pharmacol. Sci. 2009, 30, 617-623.
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 617-623
    • Bird, M.K.1    Lawrence, A.J.2
  • 104
    • 77953612697 scopus 로고    scopus 로고
    • Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction
    • Olive, M.F. Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction. Eur. J. Pharmacol. 2010, 639, 47-58.
    • (2010) Eur. J. Pharmacol. , vol.639 , pp. 47-58
    • Olive, M.F.1
  • 105
    • 70349782435 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor ligands as potential therapeutics for drug addiction
    • Olive, M.F. Metabotropic glutamate receptor ligands as potential therapeutics for drug addiction. Curr. Drug Abuse Rev. 2009, 2, 83-98.
    • (2009) Curr. Drug Abuse Rev. , vol.2 , pp. 83-98
    • Olive, M.F.1
  • 106
    • 55049123814 scopus 로고    scopus 로고
    • Antagonists at metabotropic glutamate receptor subtype 5: Structure activity relationships and therapeutic potential for addiction
    • Carroll, F.I. Antagonists at metabotropic glutamate receptor subtype 5: structure activity relationships and therapeutic potential for addiction. Ann. NY Acad. Sci. 2008, 1141, 221-232.
    • (2008) Ann. NY Acad. Sci. , vol.1141 , pp. 221-232
    • Carroll, F.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.