메뉴 건너뛰기




Volumn 61, Issue 1, 2013, Pages 22-26

The rs9939609 gene variant in FTO modified the metabolic response of weight loss after a 3-month intervention with a hypocaloric diet

Author keywords

Adipokines; Hypocaloric diet; Obesity; Rs9939609 gene variant

Indexed keywords

ADIPOCYTOKINE; INSULIN; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; RESISTIN; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84873628546     PISSN: 17088267     EISSN: 17088267     Source Type: Journal    
DOI: 10.2310/JIM.0b013e318276161d     Document Type: Article
Times cited : (23)

References (38)
  • 1
    • 41749090524 scopus 로고    scopus 로고
    • Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
    • Hinney A, Nguyen TT, Scherag A, et al. Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One. 2007;2:e1361.
    • (2007) PLoS One. , vol.2
    • Hinney, A.1    Nguyen, T.T.2    Scherag, A.3
  • 3
    • 55249098087 scopus 로고    scopus 로고
    • FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women
    • Song Y, You NC, Hsu YH, et al. FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women. Obesity (Silver Spring). 2008;16:2472-2480.
    • (2008) Obesity (Silver Spring). , vol.16 , pp. 2472-2480
    • Song, Y.1    You, N.C.2    Hsu, Y.H.3
  • 4
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science. 2007;316:889-894.
    • (2007) Science. , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 5
    • 65249108267 scopus 로고    scopus 로고
    • FTO genotype is associated with body mass index after the age of 7 years but not with energy intake or leisure-time physical activity
    • Hakanen M, Raitakari OT, Lehtimaki T, et al. FTO genotype is associated with body mass index after the age of 7 years but not with energy intake or leisure-time physical activity. J Clin Endocrinol Metab. 2009;94:1281-1287.
    • (2009) J Clin Endocrinol Metab. , vol.94 , pp. 1281-1287
    • Hakanen, M.1    Raitakari, O.T.2    Lehtimaki, T.3
  • 6
    • 53049097172 scopus 로고    scopus 로고
    • Fat mass and obesity associated gene (FTO): No significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents
    • Muller TD, Hinney A, Scherag A, et al. Fat mass and obesity associated gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents. BMC Med Genet. 2008;9:85.
    • (2008) BMC Med Genet. , vol.9 , pp. 85
    • Muller, T.D.1    Hinney, A.2    Scherag, A.3
  • 7
    • 55649096648 scopus 로고    scopus 로고
    • Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program
    • Franks PW, Jablonski KA, Delahanty LM, et al. Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program. Diabetologia. 2008;51:2214-2223.
    • (2008) Diabetologia. , vol.51 , pp. 2214-2223
    • Franks, P.W.1    Jablonski, K.A.2    Delahanty, L.M.3
  • 8
    • 63049108553 scopus 로고    scopus 로고
    • The common variant in the FTO gene did not modify the effect of lifestyle changes on body weight: The Finnish Diabetes Prevention Study
    • Lappalainen TJ, Tolppanen AM, Kolehmainen M, et al. The common variant in the FTO gene did not modify the effect of lifestyle changes on body weight: the Finnish Diabetes Prevention Study. Obesity (Silver Spring). 2009;17:832-836.
    • (2009) Obesity (Silver Spring). , vol.17 , pp. 832-836
    • Lappalainen, T.J.1    Tolppanen, A.M.2    Kolehmainen, M.3
  • 9
    • 76749144532 scopus 로고    scopus 로고
    • A 3-year intervention with a Mediterranean diet modified the association between the rs9939609 gene variant in FTO and body weight changes
    • Razquin C, Martinez JA, Martinez-Gonzalez MA, et al. A 3-year intervention with a Mediterranean diet modified the association between the rs9939609 gene variant in FTO and body weight changes. Int J Obes (Lond). 2010;34:266-272.
    • (2010) Int J Obes (Lond). , vol.34 , pp. 266-272
    • Razquin, C.1    Martinez, J.A.2    Martinez-Gonzalez, M.A.3
  • 10
    • 70450273183 scopus 로고    scopus 로고
    • Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans
    • Grau G. Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans. Int J Obes (Lond). 2010;33:1227-1234.
    • (2010) Int J Obes (Lond). , vol.33 , pp. 1227-1234
    • Grau, G.1
  • 11
    • 70350647201 scopus 로고    scopus 로고
    • Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO
    • den Hoed M, Westerterp-Plantenga MS, Bouwman FG, et al. Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. Am J Clin Nutr. 2009;90:1426-1432.
    • (2009) Am J Clin Nutr. , vol.90 , pp. 1426-1432
    • Den Hoed, M.1    Westerterp-Plantenga, M.S.2    Bouwman, F.G.3
  • 12
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis. The missing link of adipo-Vascular axis
    • Matsuda M, Shimomura I, Sata M. Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem. 2002;277:37487-37491.
    • (2002) J Biol Chem. , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3
  • 13
    • 0037231459 scopus 로고    scopus 로고
    • Association of hypoadiponectinemia with coronary artery disease in men
    • Kumada M, Kihara S, Sumitsuji S. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol. 2003;23:85-89.
    • (2003) Arterioscler Thromb Vasc Biol. , vol.23 , pp. 85-89
    • Kumada, M.1    Kihara, S.2    Sumitsuji, S.3
  • 14
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • Shimomoura I, Hammer RE, Ikemoto S. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature. 1999;401:73-76.
    • (1999) Nature. , vol.401 , pp. 73-76
    • Shimomoura, I.1    Hammer, R.E.2    Ikemoto, S.3
  • 15
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan CM, Bailey ST, Bhat S. The hormone resistin links obesity to diabetes. Nature. 2001;409:307-312.
    • (2001) Nature. , vol.409 , pp. 307-312
    • Steppan, C.M.1    Bailey, S.T.2    Bhat, S.3
  • 16
    • 15444373847 scopus 로고    scopus 로고
    • Adipocytokines: Emerging therapeutic targets
    • Matsuzawa Y. Adipocytokines: emerging therapeutic targets. Curr Atheroscler Rep. 2005;7:58-62.
    • (2005) Curr Atheroscler Rep. , vol.7 , pp. 58-62
    • Matsuzawa, Y.1
  • 18
    • 0036909707 scopus 로고    scopus 로고
    • Validation of an insulin model for the reactions in RIA
    • Duart MJ, Arroyo CO, Moreno JL. Validation of an insulin model for the reactions in RIA. Clin Chem Lab Med. 2002;40:1161-1167.
    • (2002) Clin Chem Lab Med. , vol.40 , pp. 1161-1167
    • Duart, M.J.1    Arroyo, C.O.2    Moreno, J.L.3
  • 19
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man
    • Mathews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-414.
    • (1985) Diabetologia. , vol.28 , pp. 412-414
    • Mathews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 20
    • 17544404866 scopus 로고    scopus 로고
    • Evaluation of human resistin assays with serum from patients with type 2 diabetes and different degrees of insulin resistance
    • Pfutzner A, Langefeld M, Kunt T, et al. Evaluation of human resistin assays with serum from patients with type 2 diabetes and different degrees of insulin resistance. Clin Lab. 2003;49:571-576.
    • (2003) Clin Lab. , vol.49 , pp. 571-576
    • Pfutzner, A.1    Langefeld, M.2    Kunt, T.3
  • 21
    • 4344607526 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, Ghrelin, adiponectin, and resistin
    • Meier U, Gressner M. Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, Ghrelin, adiponectin, and resistin. Clin Chem. 2004;50:1511-1525.
    • (2004) Clin Chem. , vol.50 , pp. 1511-1525
    • Meier, U.1    Gressner, M.2
  • 22
    • 1642533456 scopus 로고    scopus 로고
    • Evaluation of an enzyme immunometric assay to measure serum adiponectin concentrations
    • Suominen P. Evaluation of an enzyme immunometric assay to measure serum adiponectin concentrations. Clin Chem. 2004;50:219-221.
    • (2004) Clin Chem. , vol.50 , pp. 219-221
    • Suominen, P.1
  • 23
    • 19744379901 scopus 로고    scopus 로고
    • Usefulness of high Ysensitivity IL6 measurement for clinical characterization of patients with coronary artery disease
    • Lubrano V, Cocci F, Battaglia D, et al. Usefulness of high Ysensitivity IL6 measurement for clinical characterization of patients with coronary artery disease. J Clin Lab Anal. 2005;19:110-114.
    • (2005) J Clin Lab Anal. , vol.19 , pp. 110-114
    • Lubrano, V.1    Cocci, F.2    Battaglia, D.3
  • 24
    • 0006843644 scopus 로고
    • Bioimpedance analysis: An improved method for nutritional follow up
    • Pichard C, Slosman D, Hirschel B, et al. Bioimpedance analysis: an improved method for nutritional follow up. Clin Res. 1993;41:53.
    • (1993) Clin Res. , vol.41 , pp. 53
    • Pichard, C.1    Slosman, D.2    Hirschel, B.3
  • 25
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 2007;3:e115.
    • (2007) PLoS Genet. , vol.3
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3
  • 26
    • 73249139060 scopus 로고    scopus 로고
    • Aggravating effect of INSIG2 and FTO on overweight reduction in a one-year lifestyle intervention
    • Reinehr T, Hinney A, Toschke AM, et al. Aggravating effect of INSIG2 and FTO on overweight reduction in a one-year lifestyle intervention. Arch Dis Child. 2009;94:965-967.
    • (2009) Arch Dis Child. , vol.94 , pp. 965-967
    • Reinehr, T.1    Hinney, A.2    Toschke, A.M.3
  • 27
    • 79955852303 scopus 로고    scopus 로고
    • Body mass index change in females after short time life style intervention is not dependent on the FTO polymorphisms
    • Dlouha D, Suchanek P, Lanska V, et al. Body mass index change in females after short time life style intervention is not dependent on the FTO polymorphisms. Physiol Res. 2011;60:199-202.
    • (2011) Physiol Res. , vol.60 , pp. 199-202
    • Dlouha, D.1    Suchanek, P.2    Lanska, V.3
  • 28
    • 58149340093 scopus 로고    scopus 로고
    • Fat mass- and obesity-associated (FTO) gene variant is associated with obesity: Longitudinal analyses in two cohort studies and functional test
    • Qi L, Kang K, Zhang C, et al. Fat mass- and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. Diabetes. 2008;57:3145-3151.
    • (2008) Diabetes. , vol.57 , pp. 3145-3151
    • Qi, L.1    Kang, K.2    Zhang, C.3
  • 29
    • 47249157778 scopus 로고    scopus 로고
    • Influence of lys656Asn polymorphism of leptin receptor gene on leptin response secondary to two hypocaloric diets: A randomized clinical trial
    • de Luis DA, Aller R, Izaola O, et al. Influence of lys656Asn polymorphism of leptin receptor gene on leptin response secondary to two hypocaloric diets: a randomized clinical trial. Ann Nutr Metab. 2008;52:209-214.
    • (2008) Ann Nutr Metab. , vol.52 , pp. 209-214
    • De Luis, D.A.1    Aller, R.2    Izaola, O.3
  • 30
    • 61949159194 scopus 로고    scopus 로고
    • Modulation of insulin concentrations and metabolic parameters in obese patients by -55CT polymorphism of the UCP3 gene secondary to two hypocaloric diets
    • de Luis DA, Aller R, Izaola O, et al. Modulation of insulin concentrations and metabolic parameters in obese patients by -55CT polymorphism of the UCP3 gene secondary to two hypocaloric diets. Horm Metab Res. 2009;41:62-66.
    • (2009) Horm Metab Res. , vol.41 , pp. 62-66
    • De Luis, D.A.1    Aller, R.2    Izaola, O.3
  • 31
    • 77956624141 scopus 로고    scopus 로고
    • Effects of C358A missense polymorphism of degrading enzyme fatty acid amide hydrolase on weight loss, adipocytokines, and insulin resistance after 2 hypocaloric diets
    • de Luis DA, Sagrado MG, Aller R, et al. Effects of C358A missense polymorphism of degrading enzyme fatty acid amide hydrolase on weight loss, adipocytokines, and insulin resistance after 2 hypocaloric diets. Metabolism. 2010;59:1387-1392.
    • (2010) Metabolism. , vol.59 , pp. 1387-1392
    • De Luis, D.A.1    Sagrado, M.G.2    Aller, R.3
  • 32
    • 34249777814 scopus 로고    scopus 로고
    • Variation in FTO contributes to childhood obesity and severe adult obesity
    • Dina C, Meyre D, Gallina S. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet. 2007;3:724-726.
    • (2007) Nat Genet. , vol.3 , pp. 724-726
    • Dina, C.1    Meyre, D.2    Gallina, S.3
  • 33
    • 73949129674 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue FTO gene expression and adiposity, insulin action, glucose metabolism, and inflammatory adipokines in type 2 diabetes mellitus and in Health
    • Samaras K, Botelho N, Chisholm R, et al. Subcutaneous and visceral adipose tissue FTO gene expression and adiposity, insulin action, glucose metabolism, and inflammatory adipokines in type 2 diabetes mellitus and in Health. Obes Surg. 2010;20:108-113.
    • (2010) Obes Surg. , vol.20 , pp. 108-113
    • Samaras, K.1    Botelho, N.2    Chisholm, R.3
  • 34
    • 38449098674 scopus 로고    scopus 로고
    • Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
    • Andreasesn CH, Stender Petersen KL, Mogensen MS, et al. Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes. 2008;57:95-101.
    • (2008) Diabetes. , vol.57 , pp. 95-101
    • Andreasesn, C.H.1    Stender Petersen, K.L.2    Mogensen, M.S.3
  • 35
    • 58149302895 scopus 로고    scopus 로고
    • The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients
    • Zabena C, Gonzalez Sanchez JL, Martinez Larrad MT. The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients. Obes Surg. 2008;19:87-95.
    • (2008) Obes Surg. , vol.19 , pp. 87-95
    • Zabena, C.1    Gonzalez Sanchez, J.L.2    Martinez Larrad, M.T.3
  • 36
    • 79251575560 scopus 로고    scopus 로고
    • Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of BMI
    • Zimmermann E, Skogstrand K, Hougaard D, et al. Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of BMI. PLoS One. 2011;6:e15958-159619.
    • (2011) PLoS One. , vol.6
    • Zimmermann, E.1    Skogstrand, K.2    Hougaard, D.3
  • 37
    • 78651253434 scopus 로고    scopus 로고
    • Anti-inflammatory profile of FTO gene expression in adipose tissues from morbidly obese women
    • Terra X, Auguet T, Porras J, et al. Anti-inflammatory profile of FTO gene expression in adipose tissues from morbidly obese women. Cell Physiol Biochem. 2010;26:1041-1050.
    • (2010) Cell Physiol Biochem. , vol.26 , pp. 1041-1050
    • Terra, X.1    Auguet, T.2    Porras, J.3
  • 38
    • 77949467881 scopus 로고    scopus 로고
    • Association of FTO gene with hyperandrogenemia and metabolic parameters in women with polycystic ovary syndrome
    • Wehr E, Schweighofer N, Möller R, et al. Association of FTO gene with hyperandrogenemia and metabolic parameters in women with polycystic ovary syndrome. Metabolism. 2010;59:575-580.
    • (2010) Metabolism. , vol.59 , pp. 575-580
    • Wehr, E.1    Schweighofer, N.2    Möller, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.