메뉴 건너뛰기




Volumn 133, Issue 3, 2013, Pages 668-676

Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; SPHINGOLIPID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CTIP2; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 84873627687     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.358     Document Type: Article
Times cited : (26)

References (57)
  • 1
    • 0034616171 scopus 로고    scopus 로고
    • Isolation of a novel family of C2)H2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors
    • Avram D, Fields A, Pretty On Top K et al. (2000) Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J Biol Chem Apr 275: 10315-22
    • (2000) J Biol Chem Apr , vol.275 , pp. 10315-10322
    • Avram, D.1    Fields, A.2    Pretty On Top, K.3
  • 2
    • 0036901409 scopus 로고    scopus 로고
    • COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein
    • Avram D, Fields A, Senawong T et al. (2002) COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. Biochem J 368: 555-63
    • (2002) Biochem J , vol.368 , pp. 555-563
    • Avram, D.1    Fields, A.2    Senawong, T.3
  • 3
    • 84859778986 scopus 로고    scopus 로고
    • Structure and function of the epidermis related to barrier properties
    • Baroni A, Buommino E, De Gregorio V et al. (2012) Structure and function of the epidermis related to barrier properties. Clinics in Dermatology 30: 257-62
    • (2012) Clinics in Dermatology , vol.30 , pp. 257-262
    • Baroni, A.1    Buommino, E.2    De Gregorio, V.3
  • 4
    • 13244259440 scopus 로고    scopus 로고
    • Selective inhibition of juxtanuclear translocation of protein kinase C II by a negative feedback mechanism involving ceramide formed from the salvage pathway
    • Becker KP (2004) Selective inhibition of juxtanuclear translocation of protein kinase C II by a negative feedback mechanism involving ceramide formed from the salvage pathway. J Biol Chem 280: 2606-12
    • (2004) J Biol Chem , vol.280 , pp. 2606-2612
    • Becker, K.P.1
  • 5
    • 0029070822 scopus 로고
    • Purification, characterization, and biosynthesis of human acid ceramidase
    • Bernardo K, Hurwitz R, Zenk T et al. (1995) Purification, characterization, and biosynthesis of human acid ceramidase. J Biol Chem 270: 11098-102
    • (1995) J Biol Chem , vol.270 , pp. 11098-11102
    • Bernardo, K.1    Hurwitz, R.2    Zenk, T.3
  • 6
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-7
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 7
    • 1442323635 scopus 로고    scopus 로고
    • The epidermal permeability barrier: From the early days at Harvard to emerging concepts
    • Elias PM (2004) The epidermal permeability barrier: from the early days at Harvard to emerging concepts. J Invest Dermatol 122: xxxvi-ix
    • (2004) J Invest Dermatol , vol.122
    • Elias, P.M.1
  • 8
    • 0026265525 scopus 로고
    • Structural and lipid biochemical correlates of the epidermal permeability barrier
    • Elias PM, Menon GK (1991) Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 24: 1-26
    • (1991) Adv Lipid Res , vol.24 , pp. 1-26
    • Elias, P.M.1    Menon, G.K.2
  • 9
    • 37249053783 scopus 로고    scopus 로고
    • Thematic review series: Skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis
    • Feingold KR (2007) Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis. J Lipid Res 48: 2531-46
    • (2007) J Lipid Res , vol.48 , pp. 2531-2546
    • Feingold, K.R.1
  • 10
    • 66349097798 scopus 로고    scopus 로고
    • The outer frontier: The importance of lipid metabolism in the skin
    • Feingold KR (2009) The outer frontier: the importance of lipid metabolism in the skin. J Lipid Res 50(Suppl): S417-22
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Feingold, K.R.1
  • 11
    • 79956086824 scopus 로고    scopus 로고
    • Lipid metabolism in the epidermis
    • Feingold KR (2011) Lipid metabolism in the epidermis. Dermatoendocrinology 2: 52
    • (2011) Dermatoendocrinology , vol.2 , pp. 52
    • Feingold, K.R.1
  • 12
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 13
    • 0036245242 scopus 로고    scopus 로고
    • Getting under the skin of epidermal morphogenesis
    • Fuchs E, Raghavan S (2002) Getting under the skin of epidermal morphogenesis. Nat Rev Genet 3: 199-209
    • (2002) Nat Rev Genet , vol.3 , pp. 199-209
    • Fuchs, E.1    Raghavan, S.2
  • 14
    • 0037128938 scopus 로고    scopus 로고
    • Claudin-based tight junctions are crucial for the mammalian epidermal barrier: A lesson from claudin-1-deficient mice
    • Furuse M, Hata M, Furuse K et al. (2002) Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 156: 1099-111
    • (2002) J Cell Biol , vol.156 , pp. 1099-1111
    • Furuse, M.1    Hata, M.2    Furuse, K.3
  • 15
    • 20444363393 scopus 로고    scopus 로고
    • The ins and outs of sphingolipid synthesis
    • Futerman AH, Riezman H (2005) The ins and outs of sphingolipid synthesis. Trends Cell Biol 15: 312-8
    • (2005) Trends Cell Biol , vol.15 , pp. 312-318
    • Futerman, A.H.1    Riezman, H.2
  • 16
    • 67349110481 scopus 로고    scopus 로고
    • Dual role of COUP-TFinteracting protein 2 in epidermal homeostasis and permeability barrier formation
    • Golonzhka O, Liang X, Messaddeq N et al. (2008) Dual role of COUP-TFinteracting protein 2 in epidermal homeostasis and permeability barrier formation. J Invest Dermatol 129: 1459-70
    • (2008) J Invest Dermatol , vol.129 , pp. 1459-1470
    • Golonzhka, O.1    Liang, X.2    Messaddeq, N.3
  • 17
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • Hannun YA (1996) Functions of Ceramide in Coordinating Cellular Responses to Stress. Science 274: 1855-9
    • (1996) Science , vol.274 , pp. 1855-1859
    • Hannun, Y.A.1
  • 18
    • 34547895876 scopus 로고    scopus 로고
    • On the role of the epidermal differentiation complex in ichthyosis vulgaris, atopic dermatitis and psoriasis
    • Hoffjan S, Stemmler S (2007) On the role of the epidermal differentiation complex in ichthyosis vulgaris, atopic dermatitis and psoriasis. British J Dermatol 157: 441-9
    • (2007) British J Dermatol , vol.157 , pp. 441-449
    • Hoffjan, S.1    Stemmler, S.2
  • 19
    • 0028331151 scopus 로고
    • Consequences of betaglucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease
    • Holleran WM, Ginns EI, Menon GK et al. (1994) Consequences of betaglucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease. J Clin Invest 93: 1756-64
    • (1994) J Clin Invest , vol.93 , pp. 1756-1764
    • Holleran, W.M.1    Ginns, E.I.2    Menon, G.K.3
  • 20
    • 33749049791 scopus 로고    scopus 로고
    • Epidermal sphingolipids: Metabolism, function, and roles in skin disorders
    • Holleran WM, Takagi Y, Uchida Y (2006) Epidermal sphingolipids: metabolism, function, and roles in skin disorders. FEBS Lett 580: 5456-66
    • (2006) FEBS Lett , vol.580 , pp. 5456-5466
    • Holleran, W.M.1    Takagi, Y.2    Uchida, Y.3
  • 21
    • 77956323599 scopus 로고    scopus 로고
    • Loss of nuclear receptor RXRa in epidermal keratinocytes promotes the formation of Cdk4-activated invasive melanomas
    • Hyter S, Bajaj G, Liang X et al. (2010) Loss of nuclear receptor RXRa in epidermal keratinocytes promotes the formation of Cdk4-activated invasive melanomas. Pigment Cell Melanoma Res 23: 635-48
    • (2010) Pigment Cell Melanoma Res , vol.23 , pp. 635-648
    • Hyter, S.1    Bajaj, G.2    Liang, X.3
  • 22
    • 65649131175 scopus 로고    scopus 로고
    • A possible mechanism underlying the ceramide deficiency in atopic dermatitis: Expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide
    • Imokawa G (2009) A possible mechanism underlying the ceramide deficiency in atopic dermatitis: Expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide. J Dermatol Sci 55: 1-9
    • (2009) J Dermatol Sci , vol.55 , pp. 1-9
    • Imokawa, G.1
  • 23
    • 27744534349 scopus 로고    scopus 로고
    • Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation
    • Indra AK, Dupe V, Bornert JM et al. (2005a) Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation. Development 132: 4533-44
    • (2005) Development , vol.132 , pp. 4533-4544
    • Indra, A.K.1    Dupe, V.2    Bornert, J.M.3
  • 24
    • 24144439091 scopus 로고    scopus 로고
    • TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis
    • Indra AK, Mohan WS, Frontini M et al. (2005b) TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis. Dev Biol 285: 28-37
    • (2005) Dev Biol , vol.285 , pp. 28-37
    • Indra, A.K.1    Mohan, W.S.2    Frontini, M.3
  • 25
    • 77956878030 scopus 로고    scopus 로고
    • Changes in the ceramide profile of atopic dermatitis patients
    • Ishikawa J, Narita H, Kondo N et al. (2010) Changes in the ceramide profile of atopic dermatitis patients. J Invest Dermatol 130: 2511-4
    • (2010) J Invest Dermatol , vol.130 , pp. 2511-2514
    • Ishikawa, J.1    Narita, H.2    Kondo, N.3
  • 26
    • 80052850712 scopus 로고    scopus 로고
    • Lamellar lipid organization and ceramide composition in the stratum corneum of patients with atopic eczema
    • Janssens M, van Smeden J, Gooris GS et al. (2011) Lamellar lipid organization and ceramide composition in the stratum corneum of patients with atopic eczema. J Invest Dermatol 131: 2136-8
    • (2011) J Invest Dermatol , vol.131 , pp. 2136-2138
    • Janssens, M.1    Van Smeden, J.2    Gooris, G.S.3
  • 27
    • 84855916623 scopus 로고    scopus 로고
    • Loss of ceramide synthase 3 causes lethal skin barrier disruption
    • Jennemann R, Rabionet M, Gorgas K et al. (2012) Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet 21: 586-608
    • (2012) Hum Mol Genet , vol.21 , pp. 586-608
    • Jennemann, R.1    Rabionet, M.2    Gorgas, K.3
  • 28
    • 22744447509 scopus 로고    scopus 로고
    • Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging
    • Jensen J-M, Förl M, Winoto-Morbach S et al. (2005) Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging. Exp Dermatol 14: 609-18
    • (2005) Exp Dermatol , vol.14 , pp. 609-618
    • Jensen, J.-M.1    Förl, M.2    Winoto-Morbach, S.3
  • 30
    • 42249105215 scopus 로고    scopus 로고
    • The sphingolipid salvage pathway in ceramide metabolism and signaling
    • Kitatani K, Idkowiak-Baldys J, Hannun YA (2008) The sphingolipid salvage pathway in ceramide metabolism and signaling. Cell Signal 20: 1010-8
    • (2008) Cell Signal , vol.20 , pp. 1010-1018
    • Kitatani, K.1    Idkowiak-Baldys, J.2    Hannun, Y.A.3
  • 31
    • 84861974838 scopus 로고    scopus 로고
    • Barriers and more: Functions of tight junction proteins in the skin
    • Kirschner N, Brandner JM (2012) Barriers and more: functions of tight junction proteins in the skin. Ann N Y Acad Sci 1257: 158-66
    • (2012) Ann N y Acad Sci , vol.1257 , pp. 158-166
    • Kirschner, N.1    Brandner, J.M.2
  • 32
    • 0030479325 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease
    • Koch J, Gärtner S, Li CM et al. (1996) Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease. J Biol Chem 271: 33110-5
    • (1996) J Biol Chem , vol.271 , pp. 33110-33115
    • Koch, J.1    Gärtner, S.2    Li, C.M.3
  • 33
    • 0032104250 scopus 로고    scopus 로고
    • Cloning and characterization of the fulllength cDNA and genomic sequences encoding murine acid ceramidase
    • Li CM, Hong SB, Kopal G et al. (1998) Cloning and characterization of the fulllength cDNA and genomic sequences encoding murine acid ceramidase. Genomics 50: 267-74
    • (1998) Genomics , vol.50 , pp. 267-274
    • Li, C.M.1    Hong, S.B.2    Kopal, G.3
  • 34
    • 50049090026 scopus 로고    scopus 로고
    • Ceramidases: Regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate
    • Mao C, Obeid LM (2008) Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate. Biochimica et Biophysica Acta (BBA)-Mol Cell Biol Lipids 1781: 424-34
    • (2008) Biochimica et Biophysica Acta (BBA)-Mol Cell Biol Lipids , vol.1781 , pp. 424-434
    • Mao, C.1    Obeid, L.M.2
  • 35
    • 2342570273 scopus 로고    scopus 로고
    • Acid and neutral sphingomyelinases: Roles and mechanisms of regulation
    • Marchesini N, Hannun YA (2004) Acid and neutral sphingomyelinases: roles and mechanisms of regulation. Biochem Cell Biol 82: 27-44
    • (2004) Biochem Cell Biol , vol.82 , pp. 27-44
    • Marchesini, N.1    Hannun, Y.A.2
  • 36
    • 50949109754 scopus 로고    scopus 로고
    • Characterization of overall ceramide species in human stratum corneum
    • Masukawa Y, Narita H, Shimizu E et al. (2008) Characterization of overall ceramide species in human stratum corneum. J Lipid Res 49: 1466-76
    • (2008) J Lipid Res , vol.49 , pp. 1466-1476
    • Masukawa, Y.1    Narita, H.2    Shimizu, E.3
  • 37
    • 0037135536 scopus 로고    scopus 로고
    • De novo sphingolipid biosynthesis a necessary, but dangerous, pathway
    • Merrill AH (2002) De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway. J Biol Chem 277: 25843-6
    • (2002) J Biol Chem , vol.277 , pp. 25843-25846
    • Merrill, A.H.1
  • 38
    • 19444380734 scopus 로고    scopus 로고
    • Sphingolipidomics: Highthroughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry
    • Merrilljr A, Sullards M, Allegood J et al. (2005) Sphingolipidomics: highthroughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. Methods 36: 207-24
    • (2005) Methods , vol.36 , pp. 207-224
    • Merrilljr, A.1    Sullards, M.2    Allegood, J.3
  • 39
    • 67349094025 scopus 로고    scopus 로고
    • Ceramide biosynthesis in keratinocyte and its role in skin function
    • Mizutani Y, Mitsutake S, Tsuji K et al. (2009) Ceramide biosynthesis in keratinocyte and its role in skin function. Biochimie 91: 784-90
    • (2009) Biochimie , vol.91 , pp. 784-790
    • Mizutani, Y.1    Mitsutake, S.2    Tsuji, K.3
  • 40
    • 77955055151 scopus 로고    scopus 로고
    • Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulations
    • Monette JS, Gómez LA, Moreau RF et al. (2010) Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulations. Biochem Biophys Res Commun 398: 272-7
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 272-277
    • Monette, J.S.1    Gómez, L.A.2    Moreau, R.F.3
  • 41
    • 79151474880 scopus 로고    scopus 로고
    • R-a-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria
    • Monette JS, Gómez LA, Moreau RF et al. (2011) (R)-a-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria. Pharmacol Res 63: 23-9
    • (2011) Pharmacol Res , vol.63 , pp. 23-29
    • Monette, J.S.1    Gómez, L.A.2    Moreau, R.F.3
  • 42
    • 0027323115 scopus 로고
    • Ceramide composition of the psoriatic scale
    • Motta S, Monti M, Sesana S et al. (1993) Ceramide composition of the psoriatic scale. Biochim Biophys Acta S1182: 147-51
    • (1993) Biochim Biophys Acta , vol.S1182 , pp. 147-151
    • Motta, S.1    Monti, M.2    Sesana, S.3
  • 43
    • 0039004404 scopus 로고    scopus 로고
    • Cholesterol 3-sulfate interferes with cornified envelope assembly by diverting transglutaminase 1 activity from the formation of cross-links and esters to the hydrolysis of glutamine
    • Nemes Z, Demény M, Marekov LN et al. (2000) Cholesterol 3-sulfate interferes with cornified envelope assembly by diverting transglutaminase 1 activity from the formation of cross-links and esters to the hydrolysis of glutamine. J Biol Chem 275: 2636-46
    • (2000) J Biol Chem , vol.275 , pp. 2636-2646
    • Nemes, Z.1    Demény, M.2    Marekov, L.N.3
  • 44
    • 0033620472 scopus 로고    scopus 로고
    • Bricks and mortar of the epidermal barrier
    • Nemes Z, Steinert PM (1999) Bricks and mortar of the epidermal barrier. Exp Mol Med 31: 5-19
    • (1999) Exp Mol Med , vol.31 , pp. 5-19
    • Nemes, Z.1    Steinert, P.M.2
  • 45
    • 67349174964 scopus 로고    scopus 로고
    • Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation
    • Oda Y, Uchida Y, Moradian S et al. (2008) Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation. J Invest Dermatol 129: 1367-78
    • (2008) J Invest Dermatol , vol.129 , pp. 1367-1378
    • Oda, Y.1    Uchida, Y.2    Moradian, S.3
  • 46
    • 0037066756 scopus 로고    scopus 로고
    • Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. role for endogenous ceramide in mediating the action of exogenous ceramide
    • Ogretmen B (2002) Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. role for endogenous ceramide in mediating the action of exogenous ceramide. J Biol Chem 277: 12960-9
    • (2002) J Biol Chem , vol.277 , pp. 12960-12969
    • Ogretmen, B.1
  • 47
    • 3543114272 scopus 로고    scopus 로고
    • Biologically active sphingolipids in cancer pathogenesis and treatment
    • Ogretmen B, Hannun YA (2004) Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer 4: 604-16
    • (2004) Nat Rev Cancer , vol.4 , pp. 604-616
    • Ogretmen, B.1    Hannun, Y.A.2
  • 48
    • 77950612993 scopus 로고    scopus 로고
    • Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies
    • Park H, Haynes CA, Nairn AV et al. (2009) Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. J Lipid Res 51: 480-9
    • (2009) J Lipid Res , vol.51 , pp. 480-489
    • Park, H.1    Haynes, C.A.2    Nairn, A.V.3
  • 49
    • 0028073181 scopus 로고
    • 6-Hydroxy-4-sphingenine in human epidermal ceramides
    • Robson KJ, Stewart ME, Michelsen S et al. (1994) 6-Hydroxy-4-sphingenine in human epidermal ceramides. J Lipid Res 35: 2060-8
    • (1994) J Lipid Res , vol.35 , pp. 2060-2068
    • Robson, K.J.1    Stewart, M.E.2    Michelsen, S.3
  • 50
    • 0033832624 scopus 로고    scopus 로고
    • Permeability barrier disorder in Niemann-Pick disease: Sphingomyelin-ceramide processing required for normal barrier homeostasis
    • Schmuth M, Man MQ, Weber F et al. (2000) Permeability barrier disorder in Niemann-Pick disease: sphingomyelin-ceramide processing required for normal barrier homeostasis. J Invest Dermatol 115: 459-66
    • (2000) J Invest Dermatol , vol.115 , pp. 459-466
    • Schmuth, M.1    Man, M.Q.2    Weber, F.3
  • 51
    • 79956041030 scopus 로고    scopus 로고
    • LC/MS analysis of stratum corneum lipids: Ceramide profiling and discovery
    • van Smeden J, Hoppel L, van der Heijden R et al. (2011) LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery. J Lipid Res 52: 1211-21
    • (2011) J Lipid Res , vol.52 , pp. 1211-1221
    • Van Smeden, J.1    Hoppel, L.2    Van Der Heijden, R.3
  • 52
    • 30744433121 scopus 로고    scopus 로고
    • Regulation of the sphingosinerecycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function
    • Sultan I, Senkal CE, Ponnusamy S et al. (2006) Regulation of the sphingosinerecycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function. Biochem J 393: 513
    • (2006) Biochem J , vol.393 , pp. 513
    • Sultan, I.1    Senkal, C.E.2    Ponnusamy, S.3
  • 53
    • 0034646698 scopus 로고    scopus 로고
    • Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases
    • Tani M, Okino N, Mori K et al. (2000) Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases. J Biol Chem 275: 11229-34
    • (2000) J Biol Chem , vol.275 , pp. 11229-11234
    • Tani, M.1    Okino, N.2    Mori, K.3
  • 54
    • 0034526215 scopus 로고    scopus 로고
    • Epidermal sphingomyelins are precursors for selected stratum corneum ceramides
    • Uchida Y, Hara M, Nishio H et al. (2000) Epidermal sphingomyelins are precursors for selected stratum corneum ceramides. J Lipid Res 41: 2071-82
    • (2000) J Lipid Res , vol.41 , pp. 2071-2082
    • Uchida, Y.1    Hara, M.2    Nishio, H.3
  • 55
    • 0037377677 scopus 로고    scopus 로고
    • De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes
    • Uchida Y, Nardo AD, Collins V et al. (2003) De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. J Invest Dermatol 120: 662-9
    • (2003) J Invest Dermatol , vol.120 , pp. 662-669
    • Uchida, Y.1    Nardo, A.D.2    Collins, V.3
  • 56
    • 78650279241 scopus 로고    scopus 로고
    • RXRa ablation in epidermal keratinocytes enhances UVR-induced DNA damage, apoptosis, and proliferation of keratinocytes and melanocytes
    • Wang Z, Coleman DJ, Bajaj G et al. (2011) RXRa ablation in epidermal keratinocytes enhances UVR-induced DNA damage, apoptosis, and proliferation of keratinocytes and melanocytes. J Invest Dermatol 131: 177-87
    • (2011) J Invest Dermatol , vol.131 , pp. 177-187
    • Wang, Z.1    Coleman, D.J.2    Bajaj, G.3
  • 57
    • 79959906412 scopus 로고    scopus 로고
    • Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: A proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope
    • Zheng Y, Yin H, Boeglin WE et al. (2011) Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope. J Biol Chem 286: 24046-56
    • (2011) J Biol Chem , vol.286 , pp. 24046-24056
    • Zheng, Y.1    Yin, H.2    Boeglin, W.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.