The correlation between pain-related behaviour and spinal microgliosis in four distinct models of peripheral neuropathy

European Journal of Pain (United Kingdom)

Volumn 16, Issue 10, 2012, Pages 1357-1367

  Blackbeard, J ^a   Wallace, V C J ^a   O'Dea, K P ^a   Hasnie, F ^a   Segerdahl, A ^a   Pheby, T ^a   Field, M J ^b,c   Takata, M ^a   Rice, A S C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c GRÜNENTHAL GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; GLYCOPROTEIN GP 120; ZALCITABINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CELL COUNT; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOSIS; HERPES ZOSTER; HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; SPINE; VARICELLA ZOSTER VIRUS;

ANIMALS; ANTI-HIV AGENTS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GLIOSIS; HERPES ZOSTER; HERPESVIRUS 3, HUMAN; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; PERIPHERAL NERVE INJURIES; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, WISTAR; SPINAL CORD; SPINAL NERVES; ZALCITABINE;

EID: 84873621049     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1002/j.1532-2149.2012.00140.x     Document Type: Article

References (34)

1. Authier, N., Gillet, J.P., Fialip, J., Eschalier, A., Coudore, F. (2003). A new animal model of vincristine-induced nociceptive peripheral neuropathy. Neurotoxicology 24, 797-805.
2. Baron, R., Tolle, T.R., Gockel, U., Brosz, M., Freynhagen, R. (2009). A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: Differences in demographic data and sensory symptoms. Pain 146, 34-40.
3. Bennett, G.J., Xie, Y.K. (1988). A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33, 87-107.
4. Blackbeard, J., O'Dea, K.P., Wallace, V.C.J., Lever, I.J., Hasnie, F.S., Segerdahl, A., Pheby, T., Field, M.J., Rice, A.S.C. (2007). Quantification of the rat spinal microglial response to peripheral nerve injury as revealed by immunohistochemical image analysis and flow cytometry. J Neurosci Methods 164, 207-217.
5. Bridges, D., Ahmad, K., Rice, A.S.C. (2001). The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Br J Pharmacol 133, 586-594.
6. Clark, A.K., Gentry, C., Bradbury, E.J., McMahon, S.B., Malcangio, M. (2007). Role of spinal microglia in rat models of peripheral nerve injury and inflammation. Eur J Pain 11, 223-230.
7. Colburn, R.W., DeLeo, J.A., Rickman, A.J., Yeager, M.P., Kwon, P., Hickey, W.F. (1997). Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat. J Neuroimmunol 79, 163-175.
8. Cryan, J.F., Holmes, A. (2005). The ascent of mouse: Advances in modelling human depression and anxiety. Nat Rev Drug Discov 4, 775-790.
9. Dworkin, R.H., O'Connor, A.B., Backonja, M., Farrar, J.T., Finnerup, N.B., Jensen, T.S., Kalso, E.A., Loeser, J.D., Miaskowski, C., Nurmikko, T.J., Portenoy, R.K., Rice, A.S.C., Stacey, B.R., Treede, R-D., Turk, D.C., Wallace, M.S. (2007) Pharmacologic management of neuropathic pain: evidencebased recommendations. Pain 132, 237-251.
10. Fialip, J., Eschalier, A., Coudore, F. (2003). A new animal model of vincristine-induced nociceptive peripheral neuropathy. Neurotoxicology 24, 797-805.
11. Finnerup, N.B., Sindrup, S.H., Jensen, T.S. (2010). The evidence for pharmacological treatment of neuropathic pain. Pain 150, 573-581.
12. Flatters, S.J.L., Bennett, G.J. (2004). Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy. Pain 109, 150-161.
13. Gonzalez, J.C., Egea, J., Del Carmen, Godino M., Fernandez-Gomez, F.J., Sanchez-Prieto, J., Gandia, L., Garcia, A.G., Jordan, J., Hernandez-Guijo, J.M. (2007). Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca2+ signalling in hippocampal neurons. Eur J Neurosci 26, 2481-2495.
14. Guasti, L., Richardson, D., Jhaveri, M., Eldeeb, K., Barrett, D., Elphick, M.R., Alexander, S.P., Kendall, D., Michael, G.J., Chapman, V. (2009). Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. Mol Pain 5, 35. doi:10.1186/1744-8069-5-35.
15. Hasnie, F.S., Breuer, J., Parker, S., Wallace, V., Blackbeard, J., Lever, I., Kinchington, P.R., Dickenson, A.H., Pheby, T., Rice, A.S.C. (2007). Further characterization of a rat model of varicella zoster virus-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs. Neuroscience 144, 1495-1508.
16. Hempenstall, K., Nurmikko, T.J., Johnston, R.W., A'hern, R., Rice, A.S.C. (2005). Analgesic therapy in postherpetic neuralgia: a quantitative systematic review. Public Library of Science (PLoS) - Medicine 2(7), 628-644.
17. Joseph, E.K., Chen, X., Khasar, S.G., Levine, J.D. (2004). Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Pain 107, 147-158.
18. Kim, S.H., Chung, J.M. (1992). An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50, 355-363.
19. Kim, T.H., Kim, H.I., Kim, J., Park, M., Song, J.H. (2011). Effects of minocycline on Na+ currents in rat dorsal root ganglion neurons. Brain Res 1370, 34-42.
20. Maier, C., Baron, R., Tölle, T.R., Binder, A., Birbaumer, N., Birklein, F., Gierthmühlen, J., Flor, H., Geber, C., Huge, V., Krumova, E.K., Landwehrmeyer, G.B., Magerl, W., Maihöfner, C., Richter, H., Rolke, R., Scherens, A., Schwarz, A., Sommer, C., Tronnier, V., Uçeyler, N., Valet, M., Wasner, G., Treede, R.D. (2010). Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain 150, 439-450.
21. Maratou, K., Wallace, V.C., Hasnie, F.S., Okuse, K., Hosseini, R., Jina, N., Blackbeard, J., Pheby, T., Orengo, C., Dickenson, A.H., McMahon, S.B., Rice, A.S.C. (2009). Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain. Eur J Pain 13, 387-398.
22. Marchand, F., Perretti, M., McMahon, S.B. (2005). Role of the immune system in chronic pain. Nat Rev Neurosci 6, 521-532.
23. Polomano, R.C., Mannes, A.J., Clark, U.S., Bennett, G.J. (2001). A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel. Pain 94, 293-304.
24. Phillips, T.J.C., Cherry, C.L., Cox, S., Marshall, S.J., Rice, A.S.C. (2010). Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials. PLoS ONE 5, e14433.
25. Raghavendra, V., Tanga, F., DeLeo, J.A. (2003). Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J Pharmacol Exp Ther 306, 624-630.
26. Scholz, J., Mannion, R.J., Hord, D.E., Griffin, R.S., Rawal, B., Zheng, H., Scoffings, D., Phillips, A., Guo, J., Laing, R.J.C., Abdi, S., Decosterd, I., Woolf, C.J. (2009). A novel tool for the assessment of pain: Validation in low back pain. PLoS Med 6, e1000047.
27. Scholz, J., Woolf, C.J. (2007). The neuropathic pain triad: Neurons, immune cells and glia. Nat Neurosci 10, 1361-1368.
28. Tikka, T., Fiebich, B.L., Goldsteins, G., Keinanen, R., Koistinaho, J. (2001). Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 21, 2580-2588.
29. Tsuda, M., Inoue, K., Salter, M.W. (2005). Neuropathic pain and spinal microglia: A big problem from molecules in 'small' glia. Trends Neurosci 28, 101-107.
30. Wallace, V.C.J., Blackbeard, J., Pheby, T., Segerdahl, A.R., Davies, M., Hasnie, F., Hall, S., McMahon, S.B., Rice, A.S.C. (2007a). Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy. Pain 133, 47-63.
31. Wallace, V.C.J., Blackbeard, J., Segerdahl, A., Hasnie, F.S., Pheby, T., McMahon, S.B., Rice, A.S.C. (2007b). Characterisation of rodent models of HIV-gp120 and anti-retroviral associated neuropathic pain. Brain 130, 2688-2702.
32. Wallace, V.C.J., Segerdahl, A.R., Blackbeard, J., Pheby, T., Rice, A.S.C. (2008). Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. Neurosci Lett 448, 153-156.
33. Wallace, V.C.J., Segerdahl, A.R., Lambert, D.M., Vandevoorde, S., Blackbeard, J., Hasnie, P.T., Rice, A.S.C. (2007c). The effect of the palmitoylethanolamide analogue, palmitoylallylamide (L-29) on pain behaviour in rodent models of neuropathy. Br J Pharmacol 151(7), 1117-1128.
34. Zheng, F.Y., Xiao, W.H., Bennett, G.J. (2011). The response of spinal microglia to chemotherapy-evoked painful peripheral neuropathies is distinct from that evoked by traumatic nerve injuries. Neuroscience 176, 447-454.