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Volumn 68, Issue 3, 2013, Pages 577-586

In vitro effects of the CCR5 inhibitor maraviroc on human T cell function

Author keywords

CCR5 blockade; Chemotaxis; Immunological effects; T cell activation

Indexed keywords

CD38 ANTIGEN; CD69 ANTIGEN; CHEMOATTRACTANT; CHEMOKINE RECEPTOR CCR5; HLA DR ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MARAVIROC;

EID: 84873600564     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks432     Document Type: Article
Times cited : (36)

References (30)
  • 1
    • 77953616686 scopus 로고    scopus 로고
    • Pharmacotherapy of HIV-1 infection: focus on CCR5 antagonist maraviroc
    • Latinovic O, Kuruppu J, Davis C et al. Pharmacotherapy of HIV-1 infection: focus on CCR5 antagonist maraviroc. Clin Med Ther 2009; 1: 1497-510.
    • (2009) Clin Med Ther , vol.1 , pp. 1497-1510
    • Latinovic, O.1    Kuruppu, J.2    Davis, C.3
  • 2
    • 77749271329 scopus 로고    scopus 로고
    • Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection
    • Cooper DA, Heera J, Goodrich J et al. Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection. J Infect Dis 2010; 201: 803-13.
    • (2010) J Infect Dis , vol.201 , pp. 803-813
    • Cooper, D.A.1    Heera, J.2    Goodrich, J.3
  • 3
    • 78049319407 scopus 로고    scopus 로고
    • Effects of maraviroc and efavirenz on markers of immune activation and inflammation and associations with CD4+ cell rises in HIV-infected patients
    • Funderburg N, Kalinowska M, Eason J et al. Effects of maraviroc and efavirenz on markers of immune activation and inflammation and associations with CD4+ cell rises in HIV-infected patients. PLoS ONE 2010; 5: e13188.
    • (2010) PLoS ONE , vol.5
    • Funderburg, N.1    Kalinowska, M.2    Eason, J.3
  • 4
    • 70249120408 scopus 로고    scopus 로고
    • Impact of adding maraviroc to antiretroviral regimens in patients with full viral suppression but impaired CD4 recovery
    • Stepanyuk O, Chiang TS, Dever LL et al. Impact of adding maraviroc to antiretroviral regimens in patients with full viral suppression but impaired CD4 recovery. AIDS 2009; 23: 1911-3.
    • (2009) AIDS , vol.23 , pp. 1911-1913
    • Stepanyuk, O.1    Chiang, T.S.2    Dever, L.L.3
  • 5
    • 84858439283 scopus 로고    scopus 로고
    • T-cell changes after a short-term exposure to maraviroc in HIV-infected patients are related to antiviral activity
    • Pulido I, Machmach K, Romero-Sanchez MC et al. T-cell changes after a short-term exposure to maraviroc in HIV-infected patients are related to antiviral activity. J Infect 2012; 64: 417-23.
    • (2012) J Infect , vol.64 , pp. 417-423
    • Pulido, I.1    Machmach, K.2    Romero-Sanchez, M.C.3
  • 6
    • 84871201750 scopus 로고    scopus 로고
    • Maraviroc as intensification strategy in immunological non-responder HIV+ patients with virologic success on HAART
    • Seattle, 2012. Abstract p630. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
    • Vitiello P, Merlini E, Colella E et al. Maraviroc as intensification strategy in immunological non-responder HIV+ patients with virologic success on HAART. In: Abstracts of the Nineteenth Conference on Retroviruses and Opportunistic Infections, Seattle, 2012. Abstract p630, p. 308. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
    • Abstracts of the Nineteenth Conference on Retroviruses and Opportunistic Infections , pp. 308
    • Vitiello, P.1    Merlini, E.2    Colella, E.3
  • 7
    • 33747132429 scopus 로고    scopus 로고
    • Biology of CCR5 and its role in HIV infection and treatment
    • Lederman MM, Penn-Nicholson A, Cho M et al. Biology of CCR5 and its role in HIV infection and treatment. JAMA 2006; 296: 815-26.
    • (2006) JAMA , vol.296 , pp. 815-826
    • Lederman, M.M.1    Penn-Nicholson, A.2    Cho, M.3
  • 8
    • 65549096796 scopus 로고    scopus 로고
    • The biology of CCR5 and CXCR4
    • Alkhatib G. The biology of CCR5 and CXCR4. Curr Opin HIV AIDS 2009; 4: 96-103.
    • (2009) Curr Opin HIV AIDS , vol.4 , pp. 96-103
    • Alkhatib, G.1
  • 9
    • 18244389686 scopus 로고    scopus 로고
    • T cell costimulation by chemokine receptors
    • Molon B, Gri G, Bettella M et al. T cell costimulation by chemokine receptors. Nat Immunol 2005; 6: 465-71.
    • (2005) Nat Immunol , vol.6 , pp. 465-471
    • Molon, B.1    Gri, G.2    Bettella, M.3
  • 10
    • 70349758505 scopus 로고    scopus 로고
    • CCR5 antagonism in HIV infection: ways, effects, and side effects
    • Corbeau P, Reynes J. CCR5 antagonism in HIV infection: ways, effects, and side effects. AIDS 2009; 23: 1931-43.
    • (2009) AIDS , vol.23 , pp. 1931-1943
    • Corbeau, P.1    Reynes, J.2
  • 11
    • 33746862177 scopus 로고    scopus 로고
    • CCR5 in T cell-mediated liver diseases: what's going on?
    • Ajuebor MN, Carey JA, Swain MG. CCR5 in T cell-mediated liver diseases: what's going on? J Immunol 2006; 177: 2039-45.
    • (2006) J Immunol , vol.177 , pp. 2039-2045
    • Ajuebor, M.N.1    Carey, J.A.2    Swain, M.G.3
  • 12
    • 0035876068 scopus 로고    scopus 로고
    • The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection
    • Garcia F, Plana M, Ortiz GM et al. The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection. AIDS 2001; 15: F29-40.
    • (2001) AIDS , vol.15
    • Garcia, F.1    Plana, M.2    Ortiz, G.M.3
  • 13
    • 72949119327 scopus 로고    scopus 로고
    • Assessment of the pharmacokinetics of co-administered maraviroc and raltegravir
    • Andrews E, Glue P, Fang J et al. Assessment of the pharmacokinetics of co-administered maraviroc and raltegravir. Br J Clin Pharmacol 2010; 69: 51-7.
    • (2010) Br J Clin Pharmacol , vol.69 , pp. 51-57
    • Andrews, E.1    Glue, P.2    Fang, J.3
  • 14
    • 67650694310 scopus 로고    scopus 로고
    • A double-blind, placebocontrolled trial of maraviroc in treatment-experienced patients infected with non-R5 HIV-1
    • Saag M, Goodrich J, Fatkenheuer G et al. A double-blind, placebocontrolled trial of maraviroc in treatment-experienced patients infected with non-R5 HIV-1. J Infect Dis 2009; 199: 1638-47.
    • (2009) J Infect Dis , vol.199 , pp. 1638-1647
    • Saag, M.1    Goodrich, J.2    Fatkenheuer, G.3
  • 15
    • 77955501291 scopus 로고    scopus 로고
    • CD4+ T-cell restoration after weeks in the maraviroc treatment-experienced trials MOTIVATE 1 and 2
    • Asmuth DM, Goodrich J, Cooper DA et al. CD4+ T-cell restoration after weeks in the maraviroc treatment-experienced trials MOTIVATE 1 and 2. J Acquir Immune Defic Syndr 2010; 54: 394-7.
    • (2010) J Acquir Immune Defic Syndr , vol.54 , pp. 394-397
    • Asmuth, D.M.1    Goodrich, J.2    Cooper, D.A.3
  • 16
    • 0034623019 scopus 로고    scopus 로고
    • Immunological benefits of antiretroviral therapy in very early stages of asymptomatic chronic HIV-1 infection
    • Plana M, Garcia F, Gallart T et al. Immunological benefits of antiretroviral therapy in very early stages of asymptomatic chronic HIV-1 infection. AIDS 2000; 14: 1921-33.
    • (2000) AIDS , vol.14 , pp. 1921-1933
    • Plana, M.1    Garcia, F.2    Gallart, T.3
  • 17
    • 59849088257 scopus 로고    scopus 로고
    • CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation
    • Camargo JF, Quinones MP, Mummidi S et al. CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation. J Immunol 2009; 182: 171-82.
    • (2009) J Immunol , vol.182 , pp. 171-182
    • Camargo, J.F.1    Quinones, M.P.2    Mummidi, S.3
  • 18
    • 0037059049 scopus 로고    scopus 로고
    • Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
    • Reeves JD, Gallo SA, Ahmad N et al. Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci USA 2002; 99: 16249-54.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16249-16254
    • Reeves, J.D.1    Gallo, S.A.2    Ahmad, N.3
  • 19
    • 80053968742 scopus 로고    scopus 로고
    • HLA-DR+ CD38+ CD4+ T lymphocytes have elevated CCR5 expression and produce the majority of R5-tropic HIV-1 RNA in vivo
    • Meditz AL, Haas MK, Folkvord JM et al. HLA-DR+ CD38+ CD4+ T lymphocytes have elevated CCR5 expression and produce the majority of R5-tropic HIV-1 RNA in vivo. J Virol 2011; 85: 10189-200.
    • (2011) J Virol , vol.85 , pp. 10189-10200
    • Meditz, A.L.1    Haas, M.K.2    Folkvord, J.M.3
  • 20
    • 3843056825 scopus 로고    scopus 로고
    • Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load
    • Deeks SG, Kitchen CM, Liu L et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood 2004; 104: 942-7.
    • (2004) Blood , vol.104 , pp. 942-947
    • Deeks, S.G.1    Kitchen, C.M.2    Liu, L.3
  • 21
    • 80052038585 scopus 로고    scopus 로고
    • Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells
    • Feau S, Arens R, Togher S et al. Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells. Nat Immunol 2011; 12: 908-13.
    • (2011) Nat Immunol , vol.12 , pp. 908-913
    • Feau, S.1    Arens, R.2    Togher, S.3
  • 22
    • 0031002027 scopus 로고    scopus 로고
    • Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells
    • Carroll RG, Riley JL, Levine BL et al. Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells. Science 1997; 276: 273-6.
    • (1997) Science , vol.276 , pp. 273-276
    • Carroll, R.G.1    Riley, J.L.2    Levine, B.L.3
  • 23
    • 38149067432 scopus 로고    scopus 로고
    • The chemokine CCL5 regulates the in vivo cell surface expression of its receptor CCR5
    • Lin YL, Mettling C, Portales P et al. The chemokine CCL5 regulates the in vivo cell surface expression of its receptor, CCR5. AIDS 2008; 22: 430-2.
    • (2008) AIDS , vol.22 , pp. 430-432
    • Lin, Y.L.1    Mettling, C.2    Portales, P.3
  • 24
    • 0036485214 scopus 로고    scopus 로고
    • Chemokine receptors: multifaceted therapeutic targets
    • Proudfoot AE. Chemokine receptors: multifaceted therapeutic targets. Nat Rev Immunol 2002; 2: 106-15.
    • (2002) Nat Rev Immunol , vol.2 , pp. 106-115
    • Proudfoot, A.E.1
  • 25
    • 80053644416 scopus 로고    scopus 로고
    • vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells
    • Rossi R, Lichtner M, De RA et al. In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells. Clin Exp Immunol 2011; 166: 184-90.
    • (2011) Clin Exp Immunol , vol.166 , pp. 184-190
    • Rossi, R.1    Lichtner, M.2    De, R.A.3
  • 26
    • 61349189684 scopus 로고    scopus 로고
    • The chemokine system and CCR5 antagonists: potential in HIV treatment and other novel therapies
    • Dhami H, Fritz CE, Gankin B et al. The chemokine system and CCR5 antagonists: potential in HIV treatment and other novel therapies. J Clin Pharm Ther 2009; 34: 147-60.
    • (2009) J Clin Pharm Ther , vol.34 , pp. 147-160
    • Dhami, H.1    Fritz, C.E.2    Gankin, B.3
  • 27
    • 0035796003 scopus 로고    scopus 로고
    • CC chemokine receptor 5 and renal-transplant survival
    • Fischereder M, Luckow B, Hocher B et al. CC chemokine receptor 5 and renal-transplant survival. Lancet 2001; 357: 1758-61.
    • (2001) Lancet , vol.357 , pp. 1758-1761
    • Fischereder, M.1    Luckow, B.2    Hocher, B.3
  • 28
    • 84863375179 scopus 로고    scopus 로고
    • Frequency of T cell expressing Th1 and Th2 associated chemokine receptor in patients with renal allograft dysfunction
    • Saxena A, Panigrahi A, Gupta S et al. Frequency of T cell expressing Th1 and Th2 associated chemokine receptor in patients with renal allograft dysfunction. Transplant Proc 2012; 44: 290-5.
    • (2012) Transplant Proc , vol.44 , pp. 290-295
    • Saxena, A.1    Panigrahi, A.2    Gupta, S.3
  • 29
    • 20444375419 scopus 로고    scopus 로고
    • The clinical potential of chemokine receptor antagonists
    • Ribeiro S, Horuk R. The clinical potential of chemokine receptor antagonists. Pharmacol Ther 2005; 107: 44-58.
    • (2005) Pharmacol Ther , vol.107 , pp. 44-58
    • Ribeiro, S.1    Horuk, R.2
  • 30
    • 79957634073 scopus 로고    scopus 로고
    • Maraviroc intensification for suboptimal CD4 T cell response in a perinatally HIV-infected adolescent
    • Espiau M, Soler-Palacin P, Paredes R et al. Maraviroc intensification for suboptimal CD4 T cell response in a perinatally HIV-infected adolescent. AIDS 2011; 25: 1243-4.
    • (2011) AIDS , vol.25 , pp. 1243-1244
    • Espiau, M.1    Soler-Palacin, P.2    Paredes, R.3


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